Genomic DNA methylation changes in response to folic acid supplementation in a population-based intervention study among women of reproductive age

PLoS ONE

Volumn 6, Issue 12, 2011, Pages

  Crider, Krista S ^a   Quinlivan, Eoin P ^b   Berry, Robert J ^a   Hao, Ling ^c   Li, Zhu ^c   Maneval, David ^d   Yang, Thomas P ^e   Rasmussen, Sonja A ^a   Yang, Quanhe ^a   Zhu, Jiang Hui ^d   Hu, Dale J ^a   Bailey, Lynn B ^d  

^a NATIONAL CENTER ON BIRTH DEFECTS AND DEVELOPMENTAL DISABILITIES   (United States)

^b UNIVERSITY OF FLORIDA   (United States)

^c PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

^d UNIVERSITY OF FLORIDA   (United States)

^e UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOSINE; FOLIC ACID; GENOMIC DNA; THYMINE; CYANOCOBALAMIN; HEMOGLOBIN; METHYLENETETRAHYDROFOLATE DEHYDROGENASE (NAD);

ADULT; ARTICLE; BLOOD CLOTTING; CONTROLLED STUDY; DIET SUPPLEMENTATION; DNA ISOLATION; DNA METHYLATION; DOSE RESPONSE; DOUBLE BLIND PROCEDURE; DRUG BLOOD LEVEL; DRUG WITHDRAWAL; FEMALE; GENE; GENOTYPE; HUMAN; HUMAN CELL; INTERVENTION STUDY; MATERNAL AGE; MTHFR GENE; PHARMACOGENOMICS; POPULATION RESEARCH; RANDOMIZED CONTROLLED TRIAL; REPRODUCTION; TIME; TIME DEPENDENT; TREATMENT DURATION; TREATMENT RESPONSE; VITAMIN SUPPLEMENTATION; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; GENE EXPRESSION REGULATION; GENETIC EPIGENESIS; GENETIC VARIABILITY; GENETICS; METABOLISM; RISK;

ADULT; BLOOD COAGULATION; DIETARY SUPPLEMENTS; DNA METHYLATION; DOUBLE-BLIND METHOD; EPIGENESIS, GENETIC; FEMALE; FOLIC ACID; GENE EXPRESSION REGULATION, NEOPLASTIC; GENETIC VARIATION; GENOTYPE; HEMOGLOBINS; HUMANS; INTERVENTION STUDIES; METHYLENETETRAHYDROFOLATE DEHYDROGENASE (NAD+); ODDS RATIO; TIME FACTORS; VITAMIN B 12;

EID: 82855168079     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0028144     Document Type: Article

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