Significance of estrogen receptor 1 (ESR-1) gene imbalances in colon and hepatocellular carcinomas based on tissue microarrays analysis

Medical Oncology

Volumn 28, Issue 4, 2011, Pages 934-940

  Tsiambas, Evangelos ^a   Georgiannos, Stavros N ^b   Salemis, Nikolaos ^e   Alexopoulou, Despoina ^c   Lambropoulou, Sofia ^c   Dimo, Blerta ^c   Ioannidis, Ioannis ^c   Kravvaritis, Christos ^d   Karameris, Andreas ^e   Patsouris, Efstratios ^a   Dourakis, Spyridon ^f  

^a UNIVERSITY OF ATHENS MEDICAL SCHOOL   (Greece)

^b Blue Cross Hospital   (Greece)

^c EVANGELISMOS HOSPITAL   (Greece)

^d Department of Forensic Services ^*  (Greece)

^e 417 VA Hospital (NIMTS)   (Greece)

^f UNIVERSITY OF ATHENS   (Greece)

Author keywords

Amplification; Estrogen receptor; Gene; Liquid based cytology; Microarrays

Indexed keywords

ESTROGEN RECEPTOR ALPHA; TAMOXIFEN;

ALLELE; ANEUPLOIDY; ARTICLE; BREAST ADENOCARCINOMA; COLON CARCINOMA; FLUORESCENCE IN SITU HYBRIDIZATION; GENE AMPLIFICATION; GENE OVEREXPRESSION; HISTOGENESIS; HORMONAL THERAPY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LIVER CELL CARCINOMA; PRIORITY JOURNAL; TISSUE MICROARRAY;

ADENOCARCINOMA; BREAST NEOPLASMS; CARCINOMA, HEPATOCELLULAR; COLONIC NEOPLASMS; ESTROGEN RECEPTOR ALPHA; FEMALE; GENE AMPLIFICATION; GENE EXPRESSION PROFILING; HUMANS; IMAGE INTERPRETATION, COMPUTER-ASSISTED; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION, FLUORESCENCE; LIVER NEOPLASMS; NEOPLASM GRADING; NEOPLASM STAGING; TISSUE ARRAY ANALYSIS;

EID: 84655176821     PISSN: 13570560     EISSN: 1559131X     Source Type: Journal    
DOI: 10.1007/s12032-010-9554-8     Document Type: Article

References (28)

1. Ferlay J, Bray F, Pisani P, Parkin DM. GLOBOCAN 2000: Cancer Incidence, Mortality and Prevelence Worldwide. IACR Press, Lyon 2000.
2. DM Parkin F Bray J Ferlay P Pisani 2005 Global cancer statistics, 2002 CA Cancer J Clin 55 74 108
3. JR Pollack 2002 Microarray analysis reveals a major direct role of DNA copy number alteration in the transcriptional program of human breast tumors Proc Natl Acad Sci USA 99 20 12963 12968
4. S Knuutila K Autio Y Aalto 2000 Online access to CGH data of DNA sequence copy number changes Am J Pathol 157 2 689 690
5. R Tubbs 2009 Outcome of patients with early-stage breast cancer treated with doxorubicin-based adjuvant chemotherapy as a function of HER2 and TOP2A status J Clin Oncol 27 24 3881 3886
6. S Chia 2008 Human epidermal growth factor receptor 2 overexpression as a prognostic factor in a large tissue microarray series of node-negative breast cancers J Clin Oncol 26 35 5697 5704
7. M Hashimoto S Inoue M Muramatsu E Masliah 1997 Estrogens stimulate tamoxifen-induced neuronal cell apoptosis in vitro: a possible nongenomic action Biochem Biophys Res Commun 240 2 464 470
8. KS Korach K Chae M Gibson S Curtis 1991 Estrogen receptor stereochemistry: ligand binding and hormonal responsiveness Steroids 56 5 263 270
9. CK Osborne R Schiff 2005 Estrogen-receptor biology: continuing progress and therapeutic implications J Clin Oncol 23 1616 1622
10. F Holst 2007 Estrogen receptor alpha (ESR1) gene amplification is frequent in breast cancer Nat Genet 39 5 655 660
11. S Pancholi 2008 ERBB2 influences the subcellular localization of the estrogen receptor in tamoxifen-resistant MCF-7 cells leading to the activation of AKT and RPS6KA2 Endocr Relat Cancer 15 4 985 1002
12. L Boix 1993 et al. Sex hormone receptors in hepatocellular carcinoma. Is there a rationale for hormonal treatment? J Hepatol 17 187 191
13. Hamilton SR, Aaltonen LA, eds. Pathology and Genetics of Tumours of the Digestive System. Lyon, France: IARC Press, 2000: 221-30.
14. Tavassoli FA, Devilee P. Tumours of the breast and female genital system. Lyon, France: IARC Press, 2003: 12-112.
15. I Skaland 2008 Comparing subjective and digital image analysis HER2/neu expression scores with conventional and modified FISH scores in breast cancer J Clin Pathol 61 1 68 71
16. JS Ross 2009 Breast cancer biomarkers and HER2 testing after 10 years of anti-HER2 therapy Drug News Perspect 22 2 93 106
17. MC Tan 2009 Predictors of complete pathological response after neoadjuvant systemic therapy for breast cancer Am J Surg 198 4 520 525
18. DG Albertson C Collins F McCormick JW Gray 2003 Chromosome aberrations in solid tumors Nat Genet 34 4 369 376
19. A Vincent-Salomon V Raynal C Lucchesi N Gruel O Delattre 2008 ESR1 gene amplification in breast cancer: a common phenomenon? Nat Genet 40 7 809 Author reply 810-2
20. DG Albertson 2008 Conflicting evidence on the frequency of ESR1 amplification in breast cancer Nat Genet 40 7 821 822
21. E Shapiro 2005 Immunolocalization of androgen receptor and estrogen receptors alpha and beta in human fetal testis and epididymis J Urol 174 4 Pt 2 1695 1698
22. X Yuan 2008 Lack of association between the functional polymorphisms in the estrogen-metabolizing genes and risk for hepatocellular carcinoma Cancer Epidemiol Biomarkers Prev 17 12 3621 3627
23. Y Zhai 2006 Estrogen receptor alpha polymorphisms associated with susceptibility to hepatocellular carcinoma in hepatitis B virus carriers Gastroenterology 130 7 2001 2009
24. SF Huang HC Hsu YM Cheng TC Chang 2000 Allelic loss at chromosome band 6q14 correlates with favorable prognosis in hepatocellular carcinoma Cancer Genet Cytogenet 116 1 23 27
25. SF Huang HC Hsu JC Chen WC Chie P Lai 2003 Tetrasomy 6 and 6q14 deletion are associated with better survival in hepatocellular carcinomas. a fluorescence in situ hybridization study of 77 cases Cancer Genet Cytogenet 144 1 23 30
26. A Colantoni 2002 Variant estrogen receptors and their role in liver disease Mol Cell Endocrinol 193 1-2 65 69
27. D Pacchioni 1993 Expression of estrogen receptor mRNA in tumorous and non-tumorous liver tissue as detected by in situ hybridization J Surg Oncol Suppl 3 14 18
28. K Nakao 2004 High-resolution analysis of DNA copy number alterations in colorectal cancer by array-based comparative genomic hybridization Carcinogenesis 25 8 1345 1357