DNA methylation profiling at imprinted loci after periconceptional micronutrient supplementation in humans: Results of a pilot randomized controlled trial

FASEB Journal

Volumn 26, Issue 5, 2012, Pages 1782-1790

  Cooper, Wendy N ^a   Khulan, Batbayar ^a,b   Owens, Stephen ^c   Elks, Cathy E ^d   Seidel, Veronica ^a   Prentice, Andrew M ^c   Belteki, Gusztav ^b,e   Ong, Ken K ^b,d   Affara, Nabeel A ^b   Constância, Miguel ^a,b,f   Dunger, David B ^b,f  

^a DEPARTMENT OF OBSTETRICS AND GYNAECOLOGY   (United Kingdom)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^c MEDICAL RESEARCH COUNCIL   (United Kingdom)

^d INSTITUTE OF METABOLIC SCIENCE   (United Kingdom)

^e Rosie Maternity Hospital   (United Kingdom)

^f Cambridge Biomedical Research Centre ^*  (United Kingdom)

Author keywords

Epigenetics; Fetal programming; Maternal nutrition

Indexed keywords

ALPHA TOCOPHEROL; ASCORBIC ACID; COPPER; CYANOCOBALAMIN; DNA; FOLIC ACID; IODINE; IRON; NICOTINIC ACID; PLACEBO; PYRIDOXINE; RETINOL; RIBOFLAVIN; SELENIUM; THIAMINE; TRACE ELEMENT; VITAMIN D; ZINC;

ADOLESCENT; ADULT; ARTICLE; BLOOD SAMPLING; CARDIOVASCULAR DISEASE; CONTROLLED STUDY; CPG ISLAND; DIET; DIET SUPPLEMENTATION; DISEASE PREDISPOSITION; DNA METHYLATION; DNA SEQUENCE; EPIGENETICS; FEMALE; FETUS GROWTH; HUMAN; INFANT; LINEAR REGRESSION ANALYSIS; MAJOR CLINICAL STUDY; MALE; MOTHER; NEWBORN; NON INSULIN DEPENDENT DIABETES MELLITUS; OBESITY; OUTCOMES RESEARCH; PATIENT COMPLIANCE; PILOT STUDY; POLYMERASE CHAIN REACTION; POSTNATAL DEVELOPMENT; PREGNANCY; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; RISK; UMBILICAL CORD BLOOD;

ADOLESCENT; ADULT; DNA METHYLATION; FEMALE; GENE EXPRESSION PROFILING; HUMANS; MICRONUTRIENTS; MIDDLE AGED; PILOT PROJECTS; PLACEBOS; PRECONCEPTION CARE; YOUNG ADULT;

ANIMALIA;

EID: 84860909449     PISSN: 08926638     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.11-192708     Document Type: Article

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