메뉴 건너뛰기




Volumn 4, Issue OCT, 2013, Pages

Messages from the inside. The dynamic environment that favors intestinal homeostasis

Author keywords

DCs; Intestinal epithelial cells; Intestinal evolution; Intestinal inflammation; Mucosal immunology

Indexed keywords

APRIL PROTEIN; CD103 ANTIGEN; CD11B ANTIGEN; CHEMOKINE RECEPTOR CX3CR1; GLYCOPROTEIN P 15095; MUCIN 2; RETINOL; THYMIC STROMAL LYMPHOPOIETIN;

EID: 84885391816     PISSN: None     EISSN: 16643224     Source Type: Journal    
DOI: 10.3389/fimmu.2013.00323     Document Type: Review
Times cited : (31)

References (71)
  • 1
    • 0003660899 scopus 로고
    • From molecules to organic diversity
    • Mayr E. From molecules to organic diversity. Fed Proc (1964) 23:1231-5.
    • (1964) Fed Proc , vol.23 , pp. 1231-1235
    • Mayr, E.1
  • 2
    • 40349101808 scopus 로고    scopus 로고
    • Six major steps in animal evolution: are we derived sponge larvae?
    • doi:10.1111/j.1525-142X.2008.00231.x
    • Nielsen C. Six major steps in animal evolution: are we derived sponge larvae? Evol Dev (2008) 10:241-57. doi:10.1111/j.1525-142X.2008.00231.x.
    • (2008) Evol Dev , vol.10 , pp. 241-257
    • Nielsen, C.1
  • 3
    • 0030937838 scopus 로고    scopus 로고
    • The ctenophore Mnemiopsis leidyi has a flow-through system for digestion with three consecutive phases of extracellular digestion
    • Bumann D, Puls G. The ctenophore Mnemiopsis leidyi has a flow-through system for digestion with three consecutive phases of extracellular digestion. Physiol Zool (1997) 70:1-6.
    • (1997) Physiol Zool , vol.70 , pp. 1-6
    • Bumann, D.1    Puls, G.2
  • 4
    • 0019971522 scopus 로고
    • Phagosome-lysosome fusion inhibited by algal symbionts of Hydra viridis
    • doi:10.1083/jcb.94.1.56
    • Hohman TC, McNeil PL, Muscatine L. Phagosome-lysosome fusion inhibited by algal symbionts of Hydra viridis. J Cell Biol (1982) 94:56-63. doi:10.1083/jcb.94.1.56.
    • (1982) J Cell Biol , vol.94 , pp. 56-63
    • Hohman, T.C.1    McNeil, P.L.2    Muscatine, L.3
  • 5
    • 0036214923 scopus 로고    scopus 로고
    • The gut microflora and intestinal epithelial cells: a continuing dialogue
    • doi:10.1016/S1286-4579(02)01543-5
    • Neish AS. The gut microflora and intestinal epithelial cells: a continuing dialogue. Microbes Infect (2002) 4:309-17. doi:10.1016/S1286-4579(02)01543-5.
    • (2002) Microbes Infect , vol.4 , pp. 309-317
    • Neish, A.S.1
  • 6
    • 0036399823 scopus 로고    scopus 로고
    • How host-microbial interactions shape the nutrient environment of the mammalian intestine
    • doi:10.1146/annurev.nutr.22.011602.092259
    • Hooper LV, Midtvedt T, Gordon JI. How host-microbial interactions shape the nutrient environment of the mammalian intestine. Annu Rev Nutr (2002) 22:283-307. doi:10.1146/annurev.nutr.22.011602.092259.
    • (2002) Annu Rev Nutr , vol.22 , pp. 283-307
    • Hooper, L.V.1    Midtvedt, T.2    Gordon, J.I.3
  • 7
    • 84866168894 scopus 로고    scopus 로고
    • Functional interactions between the gut microbiota and host metabolism
    • doi:10.1038/nature11552
    • Tremaroli V, Backhed F. Functional interactions between the gut microbiota and host metabolism. Nature (2012) 489:242-9. doi:10.1038/nature11552.
    • (2012) Nature , vol.489 , pp. 242-249
    • Tremaroli, V.1    Backhed, F.2
  • 8
    • 84866528138 scopus 로고    scopus 로고
    • The price of immunity
    • doi:10.1038/ni.2422
    • Goldszmid RS, Trinchieri G. The price of immunity. Nat Immunol (2012) 13:932-8. doi:10.1038/ni.2422.
    • (2012) Nat Immunol , vol.13 , pp. 932-938
    • Goldszmid, R.S.1    Trinchieri, G.2
  • 9
    • 16244368464 scopus 로고    scopus 로고
    • Gut-level decisions in peace and war
    • doi:10.1038/nm0305-254
    • Rescigno M, Chieppa M. Gut-level decisions in peace and war. Nat Med (2005) 11:254-5. doi:10.1038/nm0305-254.
    • (2005) Nat Med , vol.11 , pp. 254-255
    • Rescigno, M.1    Chieppa, M.2
  • 10
    • 18244387204 scopus 로고    scopus 로고
    • Intestinal immune homeostasis is regulated by the crosstalk between epithelial cells and dendritic cells
    • doi:10.1038/ni1192
    • Rimoldi M, Chieppa M, Salucci V, Avogadri F, Sonzogni A, Sampietro GM, et al. Intestinal immune homeostasis is regulated by the crosstalk between epithelial cells and dendritic cells. Nat Immunol (2005) 6:507-14. doi:10.1038/ni1192.
    • (2005) Nat Immunol , vol.6 , pp. 507-514
    • Rimoldi, M.1    Chieppa, M.2    Salucci, V.3    Avogadri, F.4    Sonzogni, A.5    Sampietro, G.M.6
  • 11
    • 14544304003 scopus 로고    scopus 로고
    • Intestinal epithelial cells control dendritic cell function
    • doi:10.1196/annals.1309.009
    • Rimoldi M, Chieppa M, Vulcano M, Allavena P, Rescigno M. Intestinal epithelial cells control dendritic cell function. Ann N Y Acad Sci (2004) 1029:66-74. doi:10.1196/annals.1309.009.
    • (2004) Ann N Y Acad Sci , vol.1029 , pp. 66-74
    • Rimoldi, M.1    Chieppa, M.2    Vulcano, M.3    Allavena, P.4    Rescigno, M.5
  • 12
    • 0000733534 scopus 로고
    • Organization for physiological homeostasis
    • Cannon WB. Organization for physiological homeostasis. Physiol Rev (1929) 9(3):399-431.
    • (1929) Physiol Rev , vol.9 , Issue.3 , pp. 399-431
    • Cannon, W.B.1
  • 13
    • 36148975338 scopus 로고    scopus 로고
    • Do most lymphocytes in humans really reside in the gut?
    • doi:10.1016/j.it.2007.08.009
    • Ganusov VV, De Boer RJ. Do most lymphocytes in humans really reside in the gut? Trends Immunol (2007) 28:514-8. doi:10.1016/j.it.2007.08.009.
    • (2007) Trends Immunol , vol.28 , pp. 514-518
    • Ganusov, V.V.1    De Boer, R.J.2
  • 14
    • 1242296822 scopus 로고    scopus 로고
    • Aberrant expansion of segmented filamentous bacteria in IgA-deficient gut
    • doi:10.1073/pnas.0307317101
    • Suzuki K, Meek B, Doi Y, Muramatsu M, Chiba T, Honjo T, et al. Aberrant expansion of segmented filamentous bacteria in IgA-deficient gut. Proc Natl Acad Sci U S A (2004) 101:1981-6. doi:10.1073/pnas.0307317101.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 1981-1986
    • Suzuki, K.1    Meek, B.2    Doi, Y.3    Muramatsu, M.4    Chiba, T.5    Honjo, T.6
  • 15
    • 0034999247 scopus 로고    scopus 로고
    • Timing, localization, and persistence of colonization by segmented filamentous bacteria in the neonatal mouse gut depend on immune status of mothers and pups
    • doi:10.1128/IAI.69.6.3611-3617.2001
    • Jiang HQ, Bos NA, Cebra JJ. Timing, localization, and persistence of colonization by segmented filamentous bacteria in the neonatal mouse gut depend on immune status of mothers and pups. Infect Immun (2001) 69:3611-7. doi:10.1128/IAI.69.6.3611-3617.2001.
    • (2001) Infect Immun , vol.69 , pp. 3611-3617
    • Jiang, H.Q.1    Bos, N.A.2    Cebra, J.J.3
  • 16
    • 77954051526 scopus 로고    scopus 로고
    • Reversible microbial colonization of germ-free mice reveals the dynamics of IgA immune responses
    • doi:10.1126/science.1188454
    • Hapfelmeier S, Lawson MA, Slack E, Kirundi JK, Stoel M, Heikenwalder M, et al. Reversible microbial colonization of germ-free mice reveals the dynamics of IgA immune responses. Science (2010) 328:1705-9. doi:10.1126/science.1188454.
    • (2010) Science , vol.328 , pp. 1705-1709
    • Hapfelmeier, S.1    Lawson, M.A.2    Slack, E.3    Kirundi, J.K.4    Stoel, M.5    Heikenwalder, M.6
  • 17
    • 48549103766 scopus 로고    scopus 로고
    • Toll-like receptor signaling in small intestinal epithelium promotes B-cell recruitment and IgA production in lamina propria
    • doi:10.1053/j.gastro.2008.04.020
    • Shang L, Fukata M, Thirunarayanan N, Martin AP, Arnaboldi P, Maussang D, et al. Toll-like receptor signaling in small intestinal epithelium promotes B-cell recruitment and IgA production in lamina propria. Gastroenterology (2008) 135:529-38. doi:10.1053/j.gastro.2008.04.020.
    • (2008) Gastroenterology , vol.135 , pp. 529-538
    • Shang, L.1    Fukata, M.2    Thirunarayanan, N.3    Martin, A.P.4    Arnaboldi, P.5    Maussang, D.6
  • 19
    • 0037302651 scopus 로고    scopus 로고
    • Novel functions of the polymeric Ig receptor: well beyond transport of immunoglobulins
    • doi:10.1016/S1471-4906(02)00031-5
    • Phalipon A, Corthesy B. Novel functions of the polymeric Ig receptor: well beyond transport of immunoglobulins. Trends Immunol (2003) 24:55-8. doi:10.1016/S1471-4906(02)00031-5.
    • (2003) Trends Immunol , vol.24 , pp. 55-58
    • Phalipon, A.1    Corthesy, B.2
  • 20
    • 79959459365 scopus 로고    scopus 로고
    • Regulation of the polymeric immunoglobulin receptor by the classical and alternative NF-kappaB pathways in intestinal epithelial cells
    • doi:10.1038/mi.2011.8
    • Bruno ME, Frantz AL, Rogier EW, Johansen FE, Kaetzel CS. Regulation of the polymeric immunoglobulin receptor by the classical and alternative NF-kappaB pathways in intestinal epithelial cells. Mucosal Immunol (2011) 4:468-78. doi:10.1038/mi.2011.8.
    • (2011) Mucosal Immunol , vol.4 , pp. 468-478
    • Bruno, M.E.1    Frantz, A.L.2    Rogier, E.W.3    Johansen, F.E.4    Kaetzel, C.S.5
  • 22
    • 0028210351 scopus 로고
    • A thymic stromal cell line supports in vitro development of surface IgM+ B cells and produces a novel growth factor affecting B and T lineage cells
    • Friend SL, Hosier S, Nelson A, Foxworthe D, Williams DE, Farr A. A thymic stromal cell line supports in vitro development of surface IgM+ B cells and produces a novel growth factor affecting B and T lineage cells. Exp Hematol (1994) 22:321-8.
    • (1994) Exp Hematol , vol.22 , pp. 321-328
    • Friend, S.L.1    Hosier, S.2    Nelson, A.3    Foxworthe, D.4    Williams, D.E.5    Farr, A.6
  • 23
    • 34250205694 scopus 로고    scopus 로고
    • Intestinal bacteria trigger T cell-independent immunoglobulin A(2) class switching by inducing epithelial-cell secretion of the cytokine APRIL
    • doi:10.1016/j.immuni.2007.04.014
    • He B, Xu W, Santini PA, Polydorides AD, Chiu A, Estrella J, et al. Intestinal bacteria trigger T cell-independent immunoglobulin A(2) class switching by inducing epithelial-cell secretion of the cytokine APRIL. Immunity (2007) 26:812-26. doi:10.1016/j.immuni.2007.04.014.
    • (2007) Immunity , vol.26 , pp. 812-826
    • He, B.1    Xu, W.2    Santini, P.A.3    Polydorides, A.D.4    Chiu, A.5    Estrella, J.6
  • 24
    • 27744510433 scopus 로고    scopus 로고
    • TSLP-activated dendritic cells induce an inflammatory T helper type 2 cell response through OX40 ligand
    • doi:10.1084/jem.20051135
    • Ito T, Wang YH, Duramad O, Hori T, Delespesse GJ, Watanabe N, et al. TSLP-activated dendritic cells induce an inflammatory T helper type 2 cell response through OX40 ligand. J Exp Med (2005) 202:1213-23. doi:10.1084/jem.20051135.
    • (2005) J Exp Med , vol.202 , pp. 1213-1223
    • Ito, T.1    Wang, Y.H.2    Duramad, O.3    Hori, T.4    Delespesse, G.J.5    Watanabe, N.6
  • 25
    • 77951897845 scopus 로고    scopus 로고
    • Thymic stromal lymphopoietin-activated plasmacytoid dendritic cells induce the generation of FOXP3+ regulatory T cells in human thymus
    • doi:10.4049/jimmunol.0804106
    • Hanabuchi S, Ito T, Park WR, Watanabe N, Shaw JL, Roman E, et al. Thymic stromal lymphopoietin-activated plasmacytoid dendritic cells induce the generation of FOXP3+ regulatory T cells in human thymus. J Immunol (2010) 184:2999-3007. doi:10.4049/jimmunol.0804106.
    • (2010) J Immunol , vol.184 , pp. 2999-3007
    • Hanabuchi, S.1    Ito, T.2    Park, W.R.3    Watanabe, N.4    Shaw, J.L.5    Roman, E.6
  • 26
    • 84857221390 scopus 로고    scopus 로고
    • Dendritic cells produce TSLP that limits the differentiation of Th17 cells, fosters Treg development, and protects against colitis
    • doi:10.1038/mi.2011.64
    • Spadoni I, Iliev ID, Rossi G, Rescigno M. Dendritic cells produce TSLP that limits the differentiation of Th17 cells, fosters Treg development, and protects against colitis. Mucosal Immunol (2012) 5:184-93. doi:10.1038/mi.2011.64.
    • (2012) Mucosal Immunol , vol.5 , pp. 184-193
    • Spadoni, I.1    Iliev, I.D.2    Rossi, G.3    Rescigno, M.4
  • 27
    • 63449112387 scopus 로고    scopus 로고
    • TSLP regulates intestinal immunity and inflammation in mouse models of helminth infection and colitis
    • doi:10.1084/jem.20081499
    • Taylor BC, Zaph C, Troy AE, Du Y, Guild KJ, Comeau MR, et al. TSLP regulates intestinal immunity and inflammation in mouse models of helminth infection and colitis. J Exp Med (2009) 206:655-67. doi:10.1084/jem.20081499.
    • (2009) J Exp Med , vol.206 , pp. 655-667
    • Taylor, B.C.1    Zaph, C.2    Troy, A.E.3    Du, Y.4    Guild, K.J.5    Comeau, M.R.6
  • 28
    • 79952748335 scopus 로고    scopus 로고
    • The two mucus layers of colon are organized by the MUC2 mucin, whereas the outer layer is a legislator of host-microbial interactions
    • doi:10.1073/pnas.1006451107
    • Johansson ME, Larsson JM, Hansson GC. The two mucus layers of colon are organized by the MUC2 mucin, whereas the outer layer is a legislator of host-microbial interactions. Proc Natl Acad Sci U S A (2011) 108(Suppl 1):4659-65. doi:10.1073/pnas.1006451107.
    • (2011) Proc Natl Acad Sci U S A , vol.108 , Issue.SUPPL. 1 , pp. 4659-4665
    • Johansson, M.E.1    Larsson, J.M.2    Hansson, G.C.3
  • 29
    • 77954858707 scopus 로고    scopus 로고
    • The inner of the two Muc2 mucin-dependent mucus layers in colon is devoid of bacteria
    • doi:10.4161/gmic.1.1.10470
    • Hansson GC, Johansson ME. The inner of the two Muc2 mucin-dependent mucus layers in colon is devoid of bacteria. Gut Microbes (2010) 1:51-4. doi:10.4161/gmic.1.1.10470.
    • (2010) Gut Microbes , vol.1 , pp. 51-54
    • Hansson, G.C.1    Johansson, M.E.2
  • 31
    • 79955106916 scopus 로고    scopus 로고
    • An intestinal epithelial defect conferring ER stress results in inflammation involving both innate and adaptive immunity
    • doi:10.1038/mi.2010.74
    • Eri RD, Adams RJ, Tran TV, Tong H, Das I, Roche DK, et al. An intestinal epithelial defect conferring ER stress results in inflammation involving both innate and adaptive immunity. Mucosal Immunol (2011) 4:354-64. doi:10.1038/mi.2010.74.
    • (2011) Mucosal Immunol , vol.4 , pp. 354-364
    • Eri, R.D.1    Adams, R.J.2    Tran, T.V.3    Tong, H.4    Das, I.5    Roche, D.K.6
  • 32
    • 59749092589 scopus 로고    scopus 로고
    • Elevated human beta-defensin-2 levels indicate an activation of the innate immune system in patients with irritable bowel syndrome
    • doi:10.1038/ajg.2008.86
    • Langhorst J, Junge A, Rueffer A, Wehkamp J, Foell D, Michalsen A, et al. Elevated human beta-defensin-2 levels indicate an activation of the innate immune system in patients with irritable bowel syndrome. Am J Gastroenterol (2009) 104:404-10. doi:10.1038/ajg.2008.86.
    • (2009) Am J Gastroenterol , vol.104 , pp. 404-410
    • Langhorst, J.1    Junge, A.2    Rueffer, A.3    Wehkamp, J.4    Foell, D.5    Michalsen, A.6
  • 33
    • 77649086402 scopus 로고    scopus 로고
    • Immune adaptations that maintain homeostasis with the intestinal microbiota
    • doi:10.1038/nri2710
    • Hooper LV, Macpherson AJ. Immune adaptations that maintain homeostasis with the intestinal microbiota. Nat Rev Immunol (2010) 10:159-69. doi:10.1038/nri2710.
    • (2010) Nat Rev Immunol , vol.10 , pp. 159-169
    • Hooper, L.V.1    Macpherson, A.J.2
  • 34
    • 84862862332 scopus 로고    scopus 로고
    • Epithelial antimicrobial defence of the skin and intestine
    • doi:10.1038/nri3228
    • Gallo RL, Hooper LV. Epithelial antimicrobial defence of the skin and intestine. Nat Rev Immunol (2012) 12:503-16. doi:10.1038/nri3228.
    • (2012) Nat Rev Immunol , vol.12 , pp. 503-516
    • Gallo, R.L.1    Hooper, L.V.2
  • 35
    • 0037340434 scopus 로고    scopus 로고
    • Angiogenins: a new class of microbicidal proteins involved in innate immunity
    • doi:10.1038/ni888
    • Hooper LV, Stappenbeck TS, Hong CV, Gordon JI. Angiogenins: a new class of microbicidal proteins involved in innate immunity. Nat Immunol (2003) 4:269-73. doi:10.1038/ni888.
    • (2003) Nat Immunol , vol.4 , pp. 269-273
    • Hooper, L.V.1    Stappenbeck, T.S.2    Hong, C.V.3    Gordon, J.I.4
  • 36
    • 58549111588 scopus 로고    scopus 로고
    • Paneth cells directly sense gut commensals and maintain homeostasis at the intestinal host-microbial interface
    • doi:10.1073/pnas.0808723105
    • Vaishnava S, Behrendt CL, Ismail AS, Eckmann L, Hooper LV. Paneth cells directly sense gut commensals and maintain homeostasis at the intestinal host-microbial interface. Proc Natl Acad Sci U S A (2008) 105:20858-63. doi:10.1073/pnas.0808723105.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 20858-63
    • Vaishnava, S.1    Behrendt, C.L.2    Ismail, A.S.3    Eckmann, L.4    Hooper, L.V.5
  • 37
    • 69249158954 scopus 로고    scopus 로고
    • Human defensins activate monocyte-derived dendritic cells, promote the production of proinflammatory cytokines, and up-regulate the surface expression of CD91
    • doi:10.1189/jlb.0708412
    • Presicce P, Giannelli S, Taddeo A, Villa ML, Della BS. Human defensins activate monocyte-derived dendritic cells, promote the production of proinflammatory cytokines, and up-regulate the surface expression of CD91. J Leukoc Biol (2009) 86:941-8. doi:10.1189/jlb.0708412.
    • (2009) J Leukoc Biol , vol.86 , pp. 941-948
    • Presicce, P.1    Giannelli, S.2    Taddeo, A.3    Villa, M.L.4    Della, B.S.5
  • 38
    • 0000810758 scopus 로고
    • Lymphoid dendritic cells are potent stimulators of the primary mixed leukocyte reaction in mice
    • doi:10.1073/pnas.75.10.5132
    • Steinman RM, Witmer MD. Lymphoid dendritic cells are potent stimulators of the primary mixed leukocyte reaction in mice. Proc Natl Acad Sci U S A (1978) 75:5132-6. doi:10.1073/pnas.75.10.5132.
    • (1978) Proc Natl Acad Sci U S A , vol.75 , pp. 5132-5136
    • Steinman, R.M.1    Witmer, M.D.2
  • 39
    • 1042290501 scopus 로고    scopus 로고
    • Activation of dendritic cells: translating innate into adaptive immunity
    • doi:10.1016/j.coi.2003.11.007
    • Reis e Sousa C. Activation of dendritic cells: translating innate into adaptive immunity. Curr Opin Immunol (2004) 16:21-5. doi:10.1016/j.coi.2003.11.007.
    • (2004) Curr Opin Immunol , vol.16 , pp. 21-25
    • Reis e Sousa, C.1
  • 40
    • 34547757390 scopus 로고    scopus 로고
    • Small intestine lamina propria dendritic cells promote de novo generation of Foxp3 T reg cells via retinoic acid
    • doi:10.1084/jem.20070602
    • Sun CM, Hall JA, Blank RB, Bouladoux N, Oukka M, Mora JR, et al. Small intestine lamina propria dendritic cells promote de novo generation of Foxp3 T reg cells via retinoic acid. J Exp Med (2007) 204:1775-85. doi:10.1084/jem.20070602.
    • (2007) J Exp Med , vol.204 , pp. 1775-1785
    • Sun, C.M.1    Hall, J.A.2    Blank, R.B.3    Bouladoux, N.4    Oukka, M.5    Mora, J.R.6
  • 41
    • 33645054315 scopus 로고    scopus 로고
    • Oral tolerance originates in the intestinal immune system and relies on antigen carriage by dendritic cells
    • doi:10.1084/jem.20052016
    • Worbs T, Bode U, Yan S, Hoffmann MW, Hintzen G, Bernhardt G, et al. Oral tolerance originates in the intestinal immune system and relies on antigen carriage by dendritic cells. J Exp Med (2006) 203:519-27. doi:10.1084/jem.20052016.
    • (2006) J Exp Med , vol.203 , pp. 519-527
    • Worbs, T.1    Bode, U.2    Yan, S.3    Hoffmann, M.W.4    Hintzen, G.5    Bernhardt, G.6
  • 42
    • 0034678392 scopus 로고    scopus 로고
    • Localization of distinct Peyer's patch dendritic cell subsets and their recruitment by chemokines macrophage inflammatory protein (MIP)-3alpha, MIP-3beta, and secondary lymphoid organ chemokine
    • doi:10.1084/jem.191.8.1381
    • Iwasaki A, Kelsall BL. Localization of distinct Peyer's patch dendritic cell subsets and their recruitment by chemokines macrophage inflammatory protein (MIP)-3alpha, MIP-3beta, and secondary lymphoid organ chemokine. J Exp Med (2000) 191:1381-94. doi:10.1084/jem.191.8.1381.
    • (2000) J Exp Med , vol.191 , pp. 1381-1394
    • Iwasaki, A.1    Kelsall, B.L.2
  • 43
    • 0033584234 scopus 로고    scopus 로고
    • Freshly isolated Peyer's patch, but not spleen, dendritic cells produce interleukin 10 and induce the differentiation of T helper type 2 cells
    • doi:10.1084/jem.190.2.229
    • Iwasaki A, Kelsall BL. Freshly isolated Peyer's patch, but not spleen, dendritic cells produce interleukin 10 and induce the differentiation of T helper type 2 cells. J Exp Med (1999) 190:229-39. doi:10.1084/jem.190.2.229.
    • (1999) J Exp Med , vol.190 , pp. 229-239
    • Iwasaki, A.1    Kelsall, B.L.2
  • 44
    • 34547788180 scopus 로고    scopus 로고
    • A functionally specialized population of mucosal CD103+ DCs induces Foxp3+ regulatory T cells via a TGF-beta and retinoic acid-dependent mechanism
    • doi:10.1084/jem.20070590
    • Coombes JL, Siddiqui KR, Arancibia-Cárcamo CV, Hall J, Sun CM, Belkaid Y, et al. A functionally specialized population of mucosal CD103+ DCs induces Foxp3+ regulatory T cells via a TGF-beta and retinoic acid-dependent mechanism. J Exp Med (2007) 204:1757-64. doi:10.1084/jem.20070590.
    • (2007) J Exp Med , vol.204 , pp. 1757-1764
    • Coombes, J.L.1    Siddiqui, K.R.2    Arancibia-Cárcamo, C.V.3    Hall, J.4    Sun, C.M.5    Belkaid, Y.6
  • 45
    • 84856815290 scopus 로고    scopus 로고
    • Inflammation switches the differentiation program of Ly6Chi monocytes from antiinflammatory macrophages to inflammatory dendritic cells in the colon
    • doi:10.1084/jem.20101387
    • Rivollier A, He J, Kole A, Valatas V, Kelsall BL. Inflammation switches the differentiation program of Ly6Chi monocytes from antiinflammatory macrophages to inflammatory dendritic cells in the colon. J Exp Med (2012) 209:139-55. doi:10.1084/jem.20101387.
    • (2012) J Exp Med , vol.209 , pp. 139-155
    • Rivollier, A.1    He, J.2    Kole, A.3    Valatas, V.4    Kelsall, B.L.5
  • 46
    • 84875489998 scopus 로고    scopus 로고
    • Luminal bacteria recruit CD103+ dendritic cells into the intestinal epithelium to sample bacterial antigens for presentation
    • doi:10.1016/j.immuni.2013.01.009
    • Farache J, Koren I, Milo I, Gurevich I, Kim KW, Zigmond E, et al. Luminal bacteria recruit CD103+ dendritic cells into the intestinal epithelium to sample bacterial antigens for presentation. Immunity (2013) 38:581-95. doi:10.1016/j.immuni.2013.01.009.
    • (2013) Immunity , vol.38 , pp. 581-595
    • Farache, J.1    Koren, I.2    Milo, I.3    Gurevich, I.4    Kim, K.W.5    Zigmond, E.6
  • 47
    • 84863230541 scopus 로고    scopus 로고
    • Goblet cells deliver luminal antigen to CD103+ dendritic cells in the small intestine
    • doi:10.1038/nature10863
    • McDole JR, Wheeler LW, McDonald KG, Wang B, Konjufca V, Knoop KA, et al. Goblet cells deliver luminal antigen to CD103+ dendritic cells in the small intestine. Nature (2012) 483:345-9. doi:10.1038/nature10863.
    • (2012) Nature , vol.483 , pp. 345-349
    • McDole, J.R.1    Wheeler, L.W.2    McDonald, K.G.3    Wang, B.4    Konjufca, V.5    Knoop, K.A.6
  • 48
    • 12244297799 scopus 로고    scopus 로고
    • CX3CR1-mediated dendritic cell access to the intestinal lumen and bacterial clearance
    • doi:10.1126/science.1102901
    • Niess JH, Brand S, Gu X, Landsman L, Jung S, McCormick BA, et al. CX3CR1-mediated dendritic cell access to the intestinal lumen and bacterial clearance. Science (2005) 307:254-8. doi:10.1126/science.1102901.
    • (2005) Science , vol.307 , pp. 254-258
    • Niess, J.H.1    Brand, S.2    Gu, X.3    Landsman, L.4    Jung, S.5    McCormick, B.A.6
  • 49
    • 0035321325 scopus 로고    scopus 로고
    • Dendritic cells express tight junction proteins and penetrate gut epithelial monolayers to sample bacteria
    • doi:10.1038/86373
    • Rescigno M, Urbano M, Valzasina B, Francolini M, Rotta G, Bonasio R, et al. Dendritic cells express tight junction proteins and penetrate gut epithelial monolayers to sample bacteria. Nat Immunol (2001) 2:361-7. doi:10.1038/86373.
    • (2001) Nat Immunol , vol.2 , pp. 361-367
    • Rescigno, M.1    Urbano, M.2    Valzasina, B.3    Francolini, M.4    Rotta, G.5    Bonasio, R.6
  • 50
    • 84857635052 scopus 로고    scopus 로고
    • Peyer's patch dendritic cells sample antigens by extending dendrites through M cell-specific transcellular pores
    • doi:10.1053/j.gastro.2011.11.039
    • Lelouard H, Fallet M, de Bovis B, Meresse S, Gorvel JP. Peyer's patch dendritic cells sample antigens by extending dendrites through M cell-specific transcellular pores. Gastroenterology (2012) 142:592-601. doi:10.1053/j.gastro.2011.11.039.
    • (2012) Gastroenterology , vol.142 , pp. 592-601
    • Lelouard, H.1    Fallet, M.2    de Bovis, B.3    Meresse, S.4    Gorvel, J.P.5
  • 51
    • 64149087970 scopus 로고    scopus 로고
    • House dust mite allergen induces asthma via Toll-like receptor 4 triggering of airway structural cells
    • doi:10.1038/nm.1946
    • Hammad H, Chieppa M, Perros F, Willart MA, Germain RN, Lambrecht BN. House dust mite allergen induces asthma via Toll-like receptor 4 triggering of airway structural cells. Nat Med (2009) 15:410-6. doi:10.1038/nm.1946.
    • (2009) Nat Med , vol.15 , pp. 410-416
    • Hammad, H.1    Chieppa, M.2    Perros, F.3    Willart, M.A.4    Germain, R.N.5    Lambrecht, B.N.6
  • 52
    • 67650948293 scopus 로고    scopus 로고
    • Salmonella induces flagellin-and MyD88-dependent migration of bacteria-capturing dendritic cells into the gut lumen
    • doi:10.1053/j.gastro.2009.04.010
    • Arques JL, Hautefort I, Ivory K, Bertelli E, Regoli M, Clare S, et al. Salmonella induces flagellin-and MyD88-dependent migration of bacteria-capturing dendritic cells into the gut lumen. Gastroenterology (2009) 137(579-87):587. doi:10.1053/j.gastro.2009.04.010.
    • (2009) Gastroenterology , vol.137 , Issue.579-587 , pp. 587
    • Arques, J.L.1    Hautefort, I.2    Ivory, K.3    Bertelli, E.4    Regoli, M.5    Clare, S.6
  • 53
    • 34247877512 scopus 로고    scopus 로고
    • Mucosal dendritic cells
    • doi:10.1146/annurev.immunol.25.022106.141634
    • Iwasaki A. Mucosal dendritic cells. Annu Rev Immunol (2007) 25:381-418. doi:10.1146/annurev.immunol.25.022106.141634.
    • (2007) Annu Rev Immunol , vol.25 , pp. 381-418
    • Iwasaki, A.1
  • 54
    • 32044447002 scopus 로고    scopus 로고
    • Transepithelial pathogen uptake into the small intestinal lamina propria
    • Vallon-Eberhard A, Landsman L, Yogev N, Verrier B, Jung S. Transepithelial pathogen uptake into the small intestinal lamina propria. J Immunol (2006) 176:2465-9.
    • (2006) J Immunol , vol.176 , pp. 2465-2469
    • Vallon-Eberhard, A.1    Landsman, L.2    Yogev, N.3    Verrier, B.4    Jung, S.5
  • 55
    • 56349139080 scopus 로고    scopus 로고
    • Interactions among dendritic cells, macrophages, and epithelial cells in the gut: implications for immune tolerance
    • doi:10.1016/j.coi.2008.09.007
    • Rescigno M, Lopatin U, Chieppa M. Interactions among dendritic cells, macrophages, and epithelial cells in the gut: implications for immune tolerance. Curr Opin Immunol (2008) 20:669-75. doi:10.1016/j.coi.2008.09.007.
    • (2008) Curr Opin Immunol , vol.20 , pp. 669-675
    • Rescigno, M.1    Lopatin, U.2    Chieppa, M.3
  • 56
    • 69449102284 scopus 로고    scopus 로고
    • Innate immune signaling by Toll-like receptor-4 (TLR4) shapes the inflammatory microenvironment in colitis-associated tumors
    • doi:10.1002/ibd.20880
    • Fukata M, Hernandez Y, Conduah D, Cohen J, Chen A, Breglio K, et al. Innate immune signaling by Toll-like receptor-4 (TLR4) shapes the inflammatory microenvironment in colitis-associated tumors. Inflamm Bowel Dis (2009) 15:997-1006. doi:10.1002/ibd.20880.
    • (2009) Inflamm Bowel Dis , vol.15 , pp. 997-1006
    • Fukata, M.1    Hernandez, Y.2    Conduah, D.3    Cohen, J.4    Chen, A.5    Breglio, K.6
  • 57
    • 3242692641 scopus 로고    scopus 로고
    • Toll-like receptor 2 enhances ZO-1-associated intestinal epithelial barrier integrity via protein kinase C
    • doi:10.1053/j.gastro.2004.04.015
    • Cario E, Gerken G, Podolsky DK. Toll-like receptor 2 enhances ZO-1-associated intestinal epithelial barrier integrity via protein kinase C. Gastroenterology (2004) 127:224-38. doi:10.1053/j.gastro.2004.04.015.
    • (2004) Gastroenterology , vol.127 , pp. 224-238
    • Cario, E.1    Gerken, G.2    Podolsky, D.K.3
  • 58
    • 27144526644 scopus 로고    scopus 로고
    • Monocyte-derived dendritic cells activated by bacteria or by bacteria-stimulated epithelial cells are functionally different
    • doi:10.1182/blood-2004-11-4321
    • Rimoldi M, Chieppa M, Larghi P, Vulcano M, Allavena P, Rescigno M. Monocyte-derived dendritic cells activated by bacteria or by bacteria-stimulated epithelial cells are functionally different. Blood (2005) 106:2818-26. doi:10.1182/blood-2004-11-4321.
    • (2005) Blood , vol.106 , pp. 2818-2826
    • Rimoldi, M.1    Chieppa, M.2    Larghi, P.3    Vulcano, M.4    Allavena, P.5    Rescigno, M.6
  • 59
    • 34047173496 scopus 로고    scopus 로고
    • Epithelial NEMO links innate immunity to chronic intestinal inflammation
    • doi:10.1038/nature05698
    • Nenci A, Becker C, Wullaert A, Gareus R, van Loo G, Danese S, et al. Epithelial NEMO links innate immunity to chronic intestinal inflammation. Nature (2007) 446:557-61. doi:10.1038/nature05698.
    • (2007) Nature , vol.446 , pp. 557-561
    • Nenci, A.1    Becker, C.2    Wullaert, A.3    Gareus, R.4    van Loo, G.5    Danese, S.6
  • 60
    • 84864742470 scopus 로고    scopus 로고
    • Mechanisms used by virulent Salmonella to impair dendritic cell function and evade adaptive immunity
    • doi:10.1111/j.1365-2567.2012.03614.x
    • Bueno SM, Riquelme S, Riedel CA, Kalergis AM. Mechanisms used by virulent Salmonella to impair dendritic cell function and evade adaptive immunity. Immunology (2012) 137:28-36. doi:10.1111/j.1365-2567.2012.03614.x.
    • (2012) Immunology , vol.137 , pp. 28-36
    • Bueno, S.M.1    Riquelme, S.2    Riedel, C.A.3    Kalergis, A.M.4
  • 61
    • 0033403066 scopus 로고    scopus 로고
    • Differentiation of phagocytic monocytes into lymph node dendritic cells in vivo
    • doi:10.1016/S1074-7613(00)80149-1
    • Randolph GJ, Inaba K, Robbiani DF, Steinman RM, Muller WA. Differentiation of phagocytic monocytes into lymph node dendritic cells in vivo. Immunity (1999) 11:753-61. doi:10.1016/S1074-7613(00)80149-1.
    • (1999) Immunity , vol.11 , pp. 753-761
    • Randolph, G.J.1    Inaba, K.2    Robbiani, D.F.3    Steinman, R.M.4    Muller, W.A.5
  • 62
    • 80051636834 scopus 로고    scopus 로고
    • Thymic stromal lymphopoietin is produced by dendritic cells
    • doi:10.4049/jimmunol.1100355
    • Kashyap M, Rochman Y, Spolski R, Samsel L, Leonard WJ. Thymic stromal lymphopoietin is produced by dendritic cells. J Immunol (2011) 187:1207-11. doi:10.4049/jimmunol.1100355.
    • (2011) J Immunol , vol.187 , pp. 1207-1211
    • Kashyap, M.1    Rochman, Y.2    Spolski, R.3    Samsel, L.4    Leonard, W.J.5
  • 63
    • 37849032964 scopus 로고    scopus 로고
    • Epithelial cells prime the immune response to an array of gut-derived commensals towards a tolerogenic phenotype through distinct actions of thymic stromal lymphopoietin and transforming growth factor-beta
    • Zeuthen LH, Fink LN, Frokiaer H. Epithelial cells prime the immune response to an array of gut-derived commensals towards a tolerogenic phenotype through distinct actions of thymic stromal lymphopoietin and transforming growth factor-beta. Immunology (2008) 123:197-208.
    • (2008) Immunology , vol.123 , pp. 197-208
    • Zeuthen, L.H.1    Fink, L.N.2    Frokiaer, H.3
  • 64
    • 84872788181 scopus 로고    scopus 로고
    • Circulatory antigen processing by mucosal dendritic cells controls CD8(+) T cell activation
    • doi:10.1016/j.immuni.2012.09.018
    • Chang SY, Song JH, Guleng B, Cotoner CA, Arihiro S, Zhao Y, et al. Circulatory antigen processing by mucosal dendritic cells controls CD8(+) T cell activation. Immunity (2013) 38:153-65. doi:10.1016/j.immuni.2012.09.018.
    • (2013) Immunity , vol.38 , pp. 153-165
    • Chang, S.Y.1    Song, J.H.2    Guleng, B.3    Cotoner, C.A.4    Arihiro, S.5    Zhao, Y.6
  • 65
    • 33751223544 scopus 로고    scopus 로고
    • Generation of gut-homing IgA-secreting B cells by intestinal dendritic cells
    • doi:10.1126/science.1132742
    • Mora JR, Iwata M, Eksteen B, Song SY, Junt T, Senman B, et al. Generation of gut-homing IgA-secreting B cells by intestinal dendritic cells. Science (2006) 314:1157-60. doi:10.1126/science.1132742.
    • (2006) Science , vol.314 , pp. 1157-1160
    • Mora, J.R.1    Iwata, M.2    Eksteen, B.3    Song, S.Y.4    Junt, T.5    Senman, B.6
  • 66
    • 70349635629 scopus 로고    scopus 로고
    • All-trans retinoic acid down-regulates inflammatory responses by shifting the Treg/Th17 profile in human ulcerative and murine colitis
    • doi:10.1189/jlb.0109006
    • Bai A, Lu N, Guo Y, Liu Z, Chen J, Peng Z. All-trans retinoic acid down-regulates inflammatory responses by shifting the Treg/Th17 profile in human ulcerative and murine colitis. J Leukoc Biol (2009) 86:959-69. doi:10.1189/jlb.0109006.
    • (2009) J Leukoc Biol , vol.86 , pp. 959-969
    • Bai, A.1    Lu, N.2    Guo, Y.3    Liu, Z.4    Chen, J.5    Peng, Z.6
  • 67
    • 50249179101 scopus 로고    scopus 로고
    • Vitamin effects on the immune system: vitamins A and D take centre stage
    • doi:10.1038/nri2378
    • Mora JR, Iwata M, von Andrian UH. Vitamin effects on the immune system: vitamins A and D take centre stage. Nat Rev Immunol (2008) 8:685-98. doi:10.1038/nri2378.
    • (2008) Nat Rev Immunol , vol.8 , pp. 685-698
    • Mora, J.R.1    Iwata, M.2    von Andrian, U.H.3
  • 68
    • 34547851729 scopus 로고    scopus 로고
    • Oxidative stress and pathogenesis of inflammatory bowel disease: an epiphenomenon or the cause?
    • doi:10.1007/s10620-006-9622-2
    • Rezaie A, Parker RD, Abdollahi M. Oxidative stress and pathogenesis of inflammatory bowel disease: an epiphenomenon or the cause? Dig Dis Sci (2007) 52:2015-21. doi:10.1007/s10620-006-9622-2.
    • (2007) Dig Dis Sci , vol.52 , pp. 2015-2021
    • Rezaie, A.1    Parker, R.D.2    Abdollahi, M.3
  • 69
    • 84864021447 scopus 로고    scopus 로고
    • EF24 suppresses maturation and inflammatory response in dendritic cells
    • doi:10.1093/intimm/dxr121
    • Vilekar P, Awasthi S, Natarajan A, Anant S, Awasthi V. EF24 suppresses maturation and inflammatory response in dendritic cells. Int Immunol (2012) 24:455-64. doi:10.1093/intimm/dxr121.
    • (2012) Int Immunol , vol.24 , pp. 455-464
    • Vilekar, P.1    Awasthi, S.2    Natarajan, A.3    Anant, S.4    Awasthi, V.5
  • 70
    • 84881068658 scopus 로고    scopus 로고
    • The microbial metabolites, short-chain fatty acids, regulate colonic Treg cell homeostasis
    • doi:10.1126/science.1241165
    • Smith PM, Howitt MR, Panikov N, Michaud M, Gallini CA, Bohlooly-Y M, et al. The microbial metabolites, short-chain fatty acids, regulate colonic Treg cell homeostasis. Science (2013) 341:569-73. doi:10.1126/science.1241165.
    • (2013) Science , vol.341 , pp. 569-573
    • Smith, P.M.1    Howitt, M.R.2    Panikov, N.3    Michaud, M.4    Gallini, C.A.5    Bohlooly, Y.M.6
  • 71
    • 30944442315 scopus 로고    scopus 로고
    • A nutraceutical a day may keep the doctor away. Consumers are turning increasingly to food supplements to improve well-being when pharmaceuticals fail
    • doi:10.1038/sj.embor.7400498
    • Brower V. A nutraceutical a day may keep the doctor away. Consumers are turning increasingly to food supplements to improve well-being when pharmaceuticals fail. EMBO Rep (2005) 6(8):708-11. doi:10.1038/sj.embor.7400498.
    • (2005) EMBO Rep , vol.6 , Issue.8 , pp. 708-711
    • Brower, V.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.