메뉴 건너뛰기




Volumn 27, Issue 19, 2013, Pages 2065-2071

Exploiting the bad eating habits of Ras-driven cancers

Author keywords

Autophagy; Cancer metabolism; Glutamine; Macropinocytosis; Ras; Scavenging

Indexed keywords

GLUCOSE; GLUTAMINE; LIPID; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; SERUM ALBUMIN; PROTEIN; RAS PROTEIN;

EID: 84885357137     PISSN: 08909369     EISSN: 15495477     Source Type: Journal    
DOI: 10.1101/gad.228122.113     Document Type: Review
Times cited : (151)

References (49)
  • 2
    • 0022470480 scopus 로고
    • Induction of membrane ruffling and fluid-phase pinocytosis in quiescent fibroblasts by ras proteins
    • Bar-Sagi D, Feramisco JR. 1986. Induction of membrane ruffling and fluid-phase pinocytosis in quiescent fibroblasts by ras proteins. Science 233: 1061-1068.
    • (1986) Science , vol.233 , pp. 1061-1068
    • Bar-Sagi, D.1    Feramisco, J.R.2
  • 3
    • 79956328903 scopus 로고    scopus 로고
    • Molecular mechanisms and clinical applications of angiogenesis
    • Carmeliet P, Jain RK. 2011. Molecular mechanisms and clinical applications of angiogenesis. Nature 473: 298-307.
    • (2011) Nature , vol.473 , pp. 298-307
    • Carmeliet, P.1    Jain, R.K.2
  • 4
    • 77951209414 scopus 로고    scopus 로고
    • The role of p53 in glucose metabolism
    • Cheung EC, Vousden KH. 2010. The role of p53 in glucose metabolism. Curr Opin Cell Biol 22: 186-191.
    • (2010) Curr Opin Cell Biol , vol.22 , pp. 186-191
    • Cheung, E.C.1    Vousden, K.H.2
  • 8
    • 84860512005 scopus 로고    scopus 로고
    • Links between metabolism and cancer
    • Dang CV. 2012. Links between metabolism and cancer. Genes Dev 26: 877-890.
    • (2012) Genes Dev , vol.26 , pp. 877-890
    • Dang, C.V.1
  • 9
    • 37449034854 scopus 로고    scopus 로고
    • Beyond aerobic glycolysis: Transformed cells can engage in glutamine metabolism that exceeds the requirement for protein and nucleotide synthesis
    • DeBerardinis RJ, Mancuso A, Daikhin E, Nissim I, Yudkoff M, Wehrli S, Thompson CB. 2007. Beyond aerobic glycolysis: Transformed cells can engage in glutamine metabolism that exceeds the requirement for protein and nucleotide synthesis. Proc Natl Acad Sci 104: 19345-19350.
    • (2007) Proc Natl Acad Sci , vol.104 , pp. 19345-19350
    • Deberardinis, R.J.1    Mancuso, A.2    Daikhin, E.3    Nissim, I.4    Yudkoff, M.5    Wehrli, S.6    Thompson, C.B.7
  • 11
    • 0023158728 scopus 로고
    • Elevated levels of glucose transport and transporter messenger RNA are induced by ras or src oncogenes
    • Flier JS, Mueckler MM, Usher P, Lodish HF. 1987. Elevated levels of glucose transport and transporter messenger RNA are induced by ras or src oncogenes. Science 235: 1492-1495.
    • (1987) Science , vol.235 , pp. 1492-1495
    • Flier, J.S.1    Mueckler, M.M.2    Usher, P.3    Lodish, H.F.4
  • 12
    • 61849162778 scopus 로고    scopus 로고
    • Glutamine deprivation induces abortive S-phase rescued by deoxyribonucleotides in k-ras transformed fibroblasts
    • Gaglio D, Soldati C, Vanoni M, Alberghina L, Chiaradonna F. 2009. Glutamine deprivation induces abortive S-phase rescued by deoxyribonucleotides in k-ras transformed fibroblasts. PLoS ONE 4: e4715.
    • (2009) PLoS ONE , vol.4
    • Gaglio, D.1    Soldati, C.2    Vanoni, M.3    Alberghina, L.4    Chiaradonna, F.5
  • 14
  • 15
    • 84867142011 scopus 로고    scopus 로고
    • Regulation of lipid metabolism by p53-fighting two villains with one sword
    • Goldstein I, Rotter V. 2012. Regulation of lipid metabolism by p53-fighting two villains with one sword. Trends Endocrinol Metab 23: 567-575.
    • (2012) Trends Endocrinol Metab , vol.23 , pp. 567-575
    • Goldstein, I.1    Rotter, V.2
  • 18
    • 82555185566 scopus 로고    scopus 로고
    • Liquid chromatography-high resolution mass spectrometry analysis of fatty acid metabolism
    • Kamphorst JJ, Fan J, Lu W, White E, Rabinowitz JD. 2011. Liquid chromatography-high resolution mass spectrometry analysis of fatty acid metabolism. Anal Chem 83: 9114-9122.
    • (2011) Anal Chem , vol.83 , pp. 9114-9122
    • Kamphorst, J.J.1    Fan, J.2    Lu, W.3    White, E.4    Rabinowitz, J.D.5
  • 27
    • 81055144784 scopus 로고    scopus 로고
    • Autophagy: Renovation of cells and tissues
    • Mizushima N, Komatsu M. 2011. Autophagy: Renovation of cells and tissues. Cell 147: 728-741.
    • (2011) Cell , vol.147 , pp. 728-741
    • Mizushima, N.1    Komatsu, M.2
  • 28
    • 1542283812 scopus 로고    scopus 로고
    • In vivo analysis of autophagy in response to nutrient starvation using transgenic mice expressing a fluorescent autophagosome marker
    • Mizushima N, Yamamoto A, Matsui M, Yoshimori T, Ohsumi Y. 2004. In vivo analysis of autophagy in response to nutrient starvation using transgenic mice expressing a fluorescent autophagosome marker. Mol Biol Cell 15: 1101-1111.
    • (2004) Mol Biol Cell , vol.15 , pp. 1101-1111
    • Mizushima, N.1    Yamamoto, A.2    Matsui, M.3    Yoshimori, T.4    Ohsumi, Y.5
  • 30
    • 41649085148 scopus 로고    scopus 로고
    • A unique platform for H-Ras signaling involving clathrin-independent endocytosis
    • Porat-Shliom N, Kloog Y, Donaldson JG. 2008. A unique platform for H-Ras signaling involving clathrin-independent endocytosis. Mol Biol Cell 19: 765-775.
    • (2008) Mol Biol Cell , vol.19 , pp. 765-775
    • Porat-Shliom, N.1    Kloog, Y.2    Donaldson, J.G.3
  • 32
    • 78649704325 scopus 로고    scopus 로고
    • Autophagy and metabolism
    • Rabinowitz JD, White E. 2010. Autophagy and metabolism. Science 330: 1344-1348.
    • (2010) Science , vol.330 , pp. 1344-1348
    • Rabinowitz, J.D.1    White, E.2
  • 33
    • 0022364146 scopus 로고
    • Glycolysis and methylaminoisobutyrate uptake in rat-1 cells transfected with ras or myc oncogenes
    • Racker E, Resnick RJ, Feldman R. 1985. Glycolysis and methylaminoisobutyrate uptake in rat-1 cells transfected with ras or myc oncogenes. Proc Natl Acad Sci 82: 3535-3538.
    • (1985) Proc Natl Acad Sci , vol.82 , pp. 3535-3538
    • Racker, E.1    Resnick, R.J.2    Feldman, R.3
  • 34
    • 84859445000 scopus 로고    scopus 로고
    • Hypoxia-inducible factors: Mediators of cancer progression and targets for cancer therapy
    • Semenza GL. 2012. Hypoxia-inducible factors: Mediators of cancer progression and targets for cancer therapy. Trends Pharmacol Sci 33: 207-214.
    • (2012) Trends Pharmacol Sci , vol.33 , pp. 207-214
    • Semenza, G.L.1
  • 37
    • 66249108601 scopus 로고    scopus 로고
    • Understanding the Warburg effect: The metabolic requirements of cell proliferation
    • Vander Heiden MG, Cantley LC, Thompson CB. 2009. Understanding the Warburg effect: The metabolic requirements of cell proliferation. Science 324: 1029-1033.
    • (2009) Science , vol.324 , pp. 1029-1033
    • Vander Heiden, M.G.1    Cantley, L.C.2    Thompson, C.B.3
  • 40
    • 0035844149 scopus 로고    scopus 로고
    • Differential activation of the Rac pathway by Ha-Ras and K-Ras
    • Walsh AB, Bar-Sagi D. 2001. Differential activation of the Rac pathway by Ha-Ras and K-Ras. J Biol Chem 276: 15609-15615.
    • (2001) J Biol Chem , vol.276 , pp. 15609-15615
    • Walsh, A.B.1    Bar-Sagi, D.2
  • 41
    • 12444279265 scopus 로고
    • On the origin of cancer cells
    • Warburg O. 1956. On the origin of cancer cells. Science 123: 309-314.
    • (1956) Science , vol.123 , pp. 309-314
    • Warburg, O.1
  • 43
    • 84861526009 scopus 로고    scopus 로고
    • Deconvoluting the context-dependent role for autophagy in cancer
    • White E. 2012. Deconvoluting the context-dependent role for autophagy in cancer. Nat Rev Cancer 12: 401-410.
    • (2012) Nat Rev Cancer , vol.12 , pp. 401-410
    • White, E.1
  • 45
    • 0018123526 scopus 로고
    • Mechanism of sensitivity of cultured pancreatic carcinoma to asparaginase
    • Wu MC, Arimura GK, Yunis AA. 1978. Mechanism of sensitivity of cultured pancreatic carcinoma to asparaginase. Int J Cancer 22: 728-733.
    • (1978) Int J Cancer , vol.22 , pp. 728-733
    • Wu, M.C.1    Arimura, G.K.2    Yunis, A.A.3
  • 49
    • 34347402459 scopus 로고    scopus 로고
    • Deficiency in glutamine but not glucose induces MYC-dependent apoptosis in human cells
    • Yuneva M, Zamboni N, Oefner P, Sachidanandam R, Lazebnik Y. 2007. Deficiency in glutamine but not glucose induces MYC-dependent apoptosis in human cells. J Cell Biol 178: 93-105.
    • (2007) J Cell Biol , vol.178 , pp. 93-105
    • Yuneva, M.1    Zamboni, N.2    Oefner, P.3    Sachidanandam, R.4    Lazebnik, Y.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.