Evaluation of long-term vitamin e insufficiency or excess on bone mass, density, and microarchitecture in rodents

Free Radical Biology and Medicine

Volumn 65, Issue , 2013, Pages 1209-1214

  Iwaniec, Urszula T ^a   Turner, Russell T ^a   Smith, Brenda J ^b   Stoecker, Barbara J ^b   Rust, Allison ^a   Zhang, Bo ^a   Vasu, Vihas T ^c   Gohil, Kishorchandra ^c   Cross, Carroll E ^c   Traber, Maret G ^d  

^a OREGON STATE UNIVERSITY   (United States)

^b OKLAHOMA STATE UNIVERSITY   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d OREGON STATE UNIVERSITY   (United States)

Author keywords

Free radicals; Osteoporosis; Oxidative stress; Rodent; Skeleton; Vitamin E

Indexed keywords

ALPHA TOCOPHEROL;

ANIMAL EXPERIMENT; ARTICLE; BONE DENSITY; BONE MASS; BONE STRUCTURE; CONTROLLED STUDY; CORTICAL BONE; DUAL ENERGY X RAY ABSORPTIOMETRY; FEMALE; FEMUR; MALE; MICRO-COMPUTED TOMOGRAPHY; MOUSE; NONHUMAN; OSTEOLYSIS; PRIORITY JOURNAL; RAT; TRABECULAR BONE;

MUS; RATTUS; RODENTIA;

FREE RADICALS; OSTEOPOROSIS; OXIDATIVE STRESS; RODENT; SKELETON; VITAMIN E;

ABSORPTIOMETRY, PHOTON; AGING; ALPHA-TOCOPHEROL; ANIMALS; BONE DENSITY; CARRIER PROTEINS; DIET; FEMALE; FEMUR; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; OSTEOPOROSIS; OXIDATIVE STRESS; RATS; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES; VITAMIN E DEFICIENCY; X-RAY MICROTOMOGRAPHY;

EID: 84885336664     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2013.09.004     Document Type: Article

References (46)

1. G. Banfi, E.L. Iorio, and M.M. Corsi Oxidative stress, free radicals and bone remodeling Clin. Chem. Lab. Med. 46 2008 1550 1555
2. J.S. Alwood, K. Yumoto, R. Mojarrab, C.L. Limoli, E.A. Almeida, N.D. Searby, and R.K. Globus Heavy ion irradiation and unloading effects on mouse lumbar vertebral microarchitecture, mechanical properties and tissue stresses Bone 47 2010 248 255
3. S. Kousteni FoxOs: unifying links between oxidative stress and skeletal homeostasis Curr. Osteoporosis Rep 9 2011 60 66
4. F.A. Syed, and A.C. Ng The pathophysiology of the aging skeleton Curr. Osteoporosis Rep 8 2010 235 240
5. J. Tsay, Z. Yang, F.P. Ross, S. Cunningham-Rundles, H. Lin, R. Coleman, P. Mayer-Kuckuk, S.B. Doty, R.W. Grady, P.J. Giardina, A.L. Boskey, and M.G. Vogiatzi Bone loss caused by iron overload in a murine model: importance of oxidative stress Blood 116 2010 2582 2589
6. M.G. Traber Vitamin E J. Erdman, I. Macdonald, S. Zeisel, Present Knowledge in Nutrition 10th edition 2012 Wiley-Blackwell Ames 214 229
7. M.G. Traber, and J. Atkinson Vitamin E, antioxidant and nothing more Free Radic. Biol. Med. 43 2007 4 15 (Pubitemid 46874839)
8. N. Kono, U. Ohto, T. Hiramatsu, M. Urabe, Y. Uchida, Y. Satow, and H. Arai Impaired alpha-TTP-PIPs interaction underlies familial vitamin E deficiency Science 340 2013 1106 1110
9. M.G. Traber, L.K. Siddens, S.W. Leonard, B. Schock, K. Gohil, S.K. Krueger, C.E. Cross, and D.E. Williams α-Tocopherol modulates Cyp3a expression, increases γ-CEHC production, and limits tissue γ-tocopherol accumulation in mice fed high γ-tocopherol diets Free Radic. Biol. Med. 38 2005 773 785 (Pubitemid 40249748)
10. Y. Yoshida, N. Itoh, M. Hayakawa, Y. Habuchi, Y. Saito, Y. Tsukamoto, O. Cynshi, K. Jishage, H. Arai, and E. Niki The role of alpha-tocopherol in motor hypofunction with aging in alpha-tocopherol transfer protein knockout mice as assessed by oxidative stress biomarkers J. Nutr. Biochem. 21 2010 66 76
11. C. Cervellati, G. Bonaccorsi, E. Cremonini, C.M. Bergamini, A. Patella, C. Castaldini, S. Ferrazzini, A. Capatti, V. Picarelli, F.S. Pansini, and L. Massari Bone mass density selectively correlates with serum markers of oxidative damage in post-menopausal women. Clin. Chem Lab. Med. 51 2012 333 338
12. Y.F. He, Y. Ma, C. Gao, G.Y. Zhao, L.L. Zhang, G.F. Li, Y.Z. Pan, K. Li, and Y.J. Xu Iron overload inhibits osteoblast biological activity through oxidative stress Biol. Trace Elem. Res. 152 2013 292 296
13. S.J. Mlakar, J. Osredkar, J. Prezelj, and J. Marc Antioxidant enzymes GSR, SOD1, SOD2, and CAT gene variants and bone mineral density values in postmenopausal women: a genetic association analysis Menopause 19 2012 368 376
14. M.A. Sanchez-Rodriguez, M. Ruiz-Ramos, E. Correa-Munoz, and V.M. Mendoza-Nunez Oxidative stress as a risk factor for osteoporosis in elderly Mexicans as characterized by antioxidant enzymes BMC Musculoskeletal Disord. 8 2007 124
15. O.F. Sendur, Y. Turan, E. Tastaban, and M. Serter Antioxidant status in patients with osteoporosis: a controlled study Joint Bone Spine 76 2009 514 518
16. J.S. Tilstra, C.L. Clauson, L.J. Niedernhofer, and P.D. Robbins NF-kappaB in aging and disease Aging Dis. 2 2011 449 465
17. B. Arjmandi, S. Juma, A. Beharka, M. Bapna, M. Akhter, and S. Meydani Vitamin E improves bone quality in the aged but not in young adult male mice J. Nutr. Biochem. 13 2002 543
18. N. Muhammad, D.A. Luke, A.N. Shuid, N. Mohamed, and I.N. Soelaiman Two different isomers of vitamin E prevent bone loss in postmenopausal osteoporosis rat model. Evid. Based Complement Alternat. Med. 2012 2012 161527
19. M. Norazlina, S. Ima-Nirwana, M.T. Gapor, and B.A. Khalid Palm vitamin E is comparable to alpha-tocopherol in maintaining bone mineral density in ovariectomised female rats Exp. Clin. Endocrinol. Diabetes 108 2000 305 310 (Pubitemid 30458603)
20. B.J. Smith, E.A. Lucas, R.T. Turner, G.L. Evans, M.R. Lerner, D.J. Brackett, B.J. Stoecker, and B.H. Arjmandi Vitamin E provides protection for bone in mature hindlimb unloaded male rats Calcif. Tissue Int. 76 2005 272 279 (Pubitemid 40991398)
21. K. Fujita, M. Iwasaki, H. Ochi, T. Fukuda, C. Ma, T. Miyamoto, K. Takitani, T. Negishi-Koga, S. Sunamura, T. Kodama, H. Takayanagi, H. Tamai, S. Kato, H. Arai, K. Shinomiya, H. Itoh, A. Okawa, and S. Takeda Vitamin E decreases bone mass by stimulating osteoclast fusion Nat. Med 18 2012 589 594
22. Y. Terasawa, Z. Ladha, S.W. Leonard, J.D. Morrow, D. Newland, D. Sanan, L. Packer, M.G. Traber, and R.V. Farese Jr. Increased atherosclerosis in hyperlipidemic mice deficient in alpha-tocopherol transfer protein and vitamin E Proc. Natl. Acad. Sci. USA 97 2000 13830 13834
23. V.T. Vasu, S. Ott, B. Hobson, V. Rashidi, S. Oommen, C.E. Cross, and K. Gohil Sarcolipin and ubiquitin carboxy-terminal hydrolase 1 mRNAs are over-expressed in skeletal muscles of alpha-tocopherol deficient mice Free Radic. Res. 43 2009 106 116
24. K. Gohil, S. Oommen, H.T. Quach, V.T. Vasu, H.H. Aung, B. Schock, C.E. Cross, and G.T. Vatassery Mice lacking alpha-tocopherol transfer protein gene have severe alpha-tocopherol deficiency in multiple regions of the central nervous system Brain Res. 1201 2008 167 176
25. S.L. Cuddihy, S.S. Ali, E.S. Musiek, J. Lucero, S.J. Kopp, J.D. Morrow, and L.L. Dugan Prolonged alpha-tocopherol deficiency decreases oxidative stress and unmasks alpha-tocopherol-dependent regulation of mitochondrial function in the brain J. Biol. Chem. 283 2008 6915 6924
26. J.R. Hawse, U.T. Iwaniec, S.F. Bensamoun, D.G. Monroe, K.D. Peters, B. Ilharreborde, N.M. Rajamannan, M.J. Oursler, R.T. Turner, T.C. Spelsberg, and M. Subramaniam TIEG-null mice display an osteopenic gender-specific phenotype Bone 42 2008 1025 1031
27. U.T. Iwaniec, S. Boghossian, P.D. Lapke, R.T. Turner, and S.P. Kalra Central leptin gene therapy corrects skeletal abnormalities in leptin-deficient ob/ob mice Peptides 28 2007 1012 1019 (Pubitemid 46654437)
28. U.T. Iwaniec, M.G. Dube, S. Boghossian, H. Song, W.G. Helferich, R.T. Turner, and S.P. Kalra Body mass influences cortical bone mass independent of leptin signaling Bone 44 2009 404 412
29. U.T. Iwaniec, R.T. Turner, S.I. Koo, R. Kaur, E. Ho, C.P. Wong, and R.S. Bruno Consumption of green tea extract results in osteopenia in growing male mice J. Nutr. 139 2009 1914 1919
30. D.J. Rickard, U.T. Iwaniec, G. Evans, T.E. Hefferan, J.C. Hunter, K.M. Waters, J.P. Lydon, B.W. O'Malley, S. Khosla, T.C. Spelsberg, and R.T. Turner Bone growth and turnover in progesterone receptor knockout mice Endocrinology 149 2008 2383 2390 (Pubitemid 351574494)
31. K.M. Wiren, X.W. Zhang, D.A. Olson, R.T. Turner, and U.T. Iwaniec Androgen prevents hypogonadal bone loss via inhibition of resorption mediated by mature osteoblasts/osteocytes Bone 51 2012 835 846
32. B. Ostman, K. Michaelsson, J. Helmersson, L. Byberg, R. Gedeborg, H. Melhus, and S. Basu Oxidative stress and bone mineral density in elderly men: antioxidant activity of α-tocopherol Free Radic. Biol. Med. 47 2009 668 673
33. J.M. Mata-Granados, R. Cuenca-Acebedo, M.D. Luque de Castro, and J.M. Quesada Gomez Lower vitamin E serum levels are associated with osteoporosis in early postmenopausal women: a cross-sectional study J. Bone Miner. Metab. 31 2013 455 460
34. A.K. McNally, and J.M. Anderson Foreign body-type multinucleated giant cell formation is potently induced by alpha-tocopherol and prevented by the diacylglycerol kinase inhibitor R59022 Am. J. Pathol. 163 2003 1147 1156 (Pubitemid 37040150)
35. A. Chuin, M. Labonte, D. Tessier, A. Khalil, F. Bobeuf, C.Y. Doyon, N. Rieth, and I.J. Dionne Effect of antioxidants combined to resistance training on BMD in elderly women: a pilot study Osteoporosis Int. 20 2009 1253 1258
36. M.S. Hamidi, P.N. Corey, and A.M. Cheung Effects of vitamin E on bone turnover markers among US postmenopausal women J. Bone Miner. Res. 27 2012 1368 1380
37. M. Ruiz-Ramos, L.A. Vargas, T.I. Fortoul Van der Goes, A. Cervantes-Sandoval, and V.M. Mendoza-Nunez Supplementation of ascorbic acid and alpha-tocopherol is useful to preventing bone loss linked to oxidative stress in elderly J. Nutr. Health Aging 14 2010 467 472
38. J.A. Pasco, M.J. Henry, L.K. Wilkinson, G.C. Nicholson, H.G. Schneider, and M.A. Kotowicz Antioxidant vitamin supplements and markers of bone turnover in a community sample of nonsmoking women J. Women's Health 15 2006 295 300 (Pubitemid 43891182)
39. U.T. Iwaniec, and R.T. Turner Animal models of osteoporosis R. Marcus, D. Feldman, D.A. Nelson, C.J. Rosen, Osteoporosis 3rd edition 2008 Elsevier Amsterdam 985 1009
40. W.S. Jee, and W. Yao Overview: animal models of osteopenia and osteoporosis J. Musculoskeletal Neuronal Interact. 1 2001 193 207
41. R.G. Erben Trabecular and endocortical bone surfaces in the rat: modeling or remodeling? Anat. Rec. 246 1996 39 46 (Pubitemid 26305130)
42. M. Rusconi, A. Valleriana, J.W.C. Dunlop, J. Kurths, and R. Weinkamer Quantitative approach to the stochastics of bone remodeling Europhys. Lett. 97 2012 28009
43. R.T. Turner, S.P. Kalra, C.P. Wong, K.A. Philbrick, L.B. Lindenmaier, S. Boghossian, and U.T. Iwaniec Peripheral leptin regulates bone formation J. Bone Miner. Res. 28 2013 22 34
44. A.N. Shuid, S. Mohamad, N. Muhammad, F.M. Fadzilah, S.A. Mokhtar, N. Mohamed, and I.N. Soelaiman Effects of alpha-tocopherol on the early phase of osteoporotic fracture healing J. Orthop. Res. 29 2011 1732 1738
45. H.Y. Huang, and L.J. Appel Supplementation of diets with alpha-tocopherol reduces serum concentrations of gamma- and delta-tocopherol in humans J. Nutr. 133 2003 3137 3140 (Pubitemid 37222228)
46. M.G. Traber Mechanisms for the prevention of vitamin E excess J. Lipid Res. 54 2013 2295 2306