Lower vitamin e serum levels are associated with osteoporosis in early postmenopausal women: A cross-sectional study

Journal of Bone and Mineral Metabolism

Volumn 31, Issue 4, 2013, Pages 455-460

  Mata Granados, José M ^a,b   Cuenca Acebedo, Rafael ^b,c   Luque De Castro, María Dolores ^b   Quesada Gómez, José M ^a,b,c  

^a Sanyres Group   (Spain)

^b UNIVERSITY OF CÓRDOBA   (Spain)

^c HOSPITAL UNIVERSITARIO REINA SOFÍA   (Spain)

Author keywords

Bone mineral density; Early postmenopausal women; Osteoporosis; Vitamin E

Indexed keywords

25 HYDROXYVITAMIN D; ALKALINE PHOSPHATASE; ALPHA TOCOPHEROL; CALCIUM; LIPID; OSTEOCALCIN;

ADULT; AGE; ALCOHOL CONSUMPTION; ALPHA TOCOPHEROL BLOOD LEVEL; ANTHROPOMETRIC PARAMETERS; ARTICLE; BODY MASS; BONE DENSITY; CLINICAL ARTICLE; CROSS-SECTIONAL STUDY; DISEASE ASSOCIATION; FEMALE; HUMAN; LEISURE; LUMBAR SPINE; OSTEOPENIA; PHYSICAL ACTIVITY; POSTMENOPAUSE OSTEOPOROSIS; PRIORITY JOURNAL; RISK ASSESSMENT; RISK FACTOR; SMOKING; VITAMIN BLOOD LEVEL; ANTHROPOMETRY; BLOOD; FEMUR NECK; LUMBAR VERTEBRA; MIDDLE AGED; MULTIVARIATE ANALYSIS; OSTEOPOROSIS, POSTMENOPAUSAL; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; STATISTICAL MODEL;

ANTHROPOMETRY; BONE DENSITY; CROSS-SECTIONAL STUDIES; FEMALE; FEMUR NECK; HUMANS; LINEAR MODELS; LUMBAR VERTEBRAE; MIDDLE AGED; MULTIVARIATE ANALYSIS; OSTEOPOROSIS, POSTMENOPAUSAL; VITAMIN E;

EID: 84880275561     PISSN: 09148779     EISSN: 14355604     Source Type: Journal    
DOI: 10.1007/s00774-013-0432-2     Document Type: Article

References (36)

1. Manolagas SC (2010) From estrogen-centric to aging and oxidative stress: a revised perspective of the pathogenesis of osteoporosis. Endocr Rev 31:266-300
2. Balaban RS, Nemoto S, Finkel T (2005) Mitochondria, oxidants, and aging. Cell 120:483-495 (Pubitemid 40269763)
3. Xu H, Watkins BA, Seifert MF (1995) Vitamin E stimulates trabecular bone formation and alters epiphyseal cartilage morphometry. Calcif Tissue Int 57:293-300
4. Ima-Nirwana S, Kiftiah A, Sariza T, Gapor MT, Khalid BAK (1999) Palm vitamin E improves bone metabolism and survival rate in thyrotoxic rats. Gen Pharmacol 32:621-626 (Pubitemid 29219467)
5. Ima-Nirwana S, Norazlina M, Khalid BAK (2000) Palm vitamin E prevents osteoporosis in orchidectomized growing male rats. Nat Prod Sci 694:155-160 (Pubitemid 32249500)
6. Norazlina M, Ima-Nirwana S, Gapor MT, Khalid BAK (2000) Palm vitamin E is comparable to alpha-tocopherol in maintaining bone mineral density in ovariectomised female rats. Exp Clin Endocrinol Diabetes 108:305-310 (Pubitemid 30458603)
7. Ima-Nirwana S, Fakhrurazi H (2002) Palm vitamin E protects bone against dexamethasone-induced osteoporosis in male rats. Med J Malaysia 57:136-144
8. Ahmad NS, Khalid BAK, Luke DA, Ima-Nirwana S (2005) Tocotrienol offers better protection than tocopherol from free radical-induced damage of rat bone. Clin Exp Pharmacol Physiol 32:761-770 (Pubitemid 41603156)
9. Ahmad NS, Zulfadli M, Norazlina M, Norliza M, Ima-Nirwana S (2010) Vitamin E exhibits bone anabolic actions in normal male rats. J Bone Miner Metab 28:149-156
10. Melhus H, Michaëlsson K, Holmberg L, Wolk A, Junghall S (1999) Smoking, antioxidant vitamins, and risk of hip fracture. J Bone Miner Res 14:129-135 (Pubitemid 29021613)
11. Zhang J, Munger RG, West NA, Cutler DR, Wengreen HJ, Corcoran CD (2006) Antioxidant intake and risk of osteoporotic hip fracture in Utah: an effect modified by smoking status. Am J Epidemiol 163:9-17 (Pubitemid 43007110)
12. Maggio D, Barabani M, Pierandrei M, Polidori MC, Catani M, Mecocci P, Senin U, Pacifici R, Cherubini A (2003) Marked decrease in plasma antioxidants in aged osteoporotic women: results of a cross-sectional study. J Clin Endocrinol Metab 88:1523-1527 (Pubitemid 36623364)
13. O′Neill TW, Cooper C, Cannata JB, Díaz López JB, Hoszowski K, Johnell O, Lorenc RS, Nilsson B, Raspe H, Stewart O, Silman AJ, On behalf of the European Vertebral Osteoporosis Study (EVOS) group (1994) Reproducibility of a questionnaire on risk factors for osteoporosis in a multicentre prevalence survey: the European Vertebral Osteoporosis Study. Int J Epidemiol 23:559-565 (Pubitemid 24214862)
14. Mata-Granados JM, Quesada Gómez JM, Luque de Castro MD (2009) Fully automatic method for the determination of fat soluble vitamins and vitamin D metabolites in serum. Clin Chim Acta 403:126-130
15. Thurnham DI, Davies JA, Crump BJ, Situnayake RD, Davis M (1986) The use of different lipids to express serum tocopherol:lipid ratios for the measurement of vitamin E status. Ann Clin Biochem 23:514-520 (Pubitemid 16042484)
16. Kanis JA, Melton LJ, Christiansen C, Johnston CC, Khaltaev N (1994) The diagnosis of osteoporosis. J Bone Miner Res 9:1137-1141 (Pubitemid 24985932)
17. García-Closas R, Berenguer A, José Tormo M, José Sánchez M, Quirós JR, Navarro C, Arnaud R, Dorronsoro M, Dolores Chirlaque M, Barricarte A, Ardanaz E, Amiano P, Martinez C, Agudo A, González CA (2004) Dietary sources of vitamin C, vitamin E and specific carotenoids in Spain. Br J Nutr 91:1005-1011 (Pubitemid 38931465)
18. Olmedilla B, Granado F, Southon S, Wright AJ, Blanco I, Gil-Martinez E, Berg H, Corridan B, Roussel AM, Chopra M, Thurnham DI (2001) Serum concentrations of carotenoids and vitamins A, E, and C in control subjects from five European countries. Br J Nutr 85:227-238 (Pubitemid 32236810)
19. Abhaya A, Khatri K, Pradhan S, Prakash R (2003) Effect of alpha tocopherol on the growth plate of albino rats. J Anat Soc India 52:58-63
20. Maggio D, Polidori MC, Barabani M et al (2006) Low levels of carotenoids and retinol in involutional osteoporosis. Bone 38:244-248 (Pubitemid 43168318)
21. Yang Z, Zhang Z, Penniston KL, Binkley N, Tanumihardjo SA (2008) Serum carotenoid concentrations in postmenopausal women from the United States with and without osteoporosis. Int J Vitam Nutr Res 78:105-111
22. Sahni S, Hannan MT, Blumberg J, Cupples LA, Kiel DP, Tucker KL (2009) Inverse association of carotenoid intakes with 4-y change in bone mineral density in elderly men and women: the Framingham Osteoporosis Study. Am J Clin Nutr 89:416-424
23. Sahni S, Hannan MT, Gagnon D, Blumberg J, Cupples LA, Kiel DP, Tucker KL (2009) Protective effect of total and supplemental vitamin C intake on the risk of hip fracture - a 17-year follow-up from the Framingham Osteoporosis Study. Osteoporos Int 20:1853-1861
24. Basu S, Michaëlsson K, Olofsson H, Johansson S, Melhus H (2001) Association between oxidative stress and bone mineral density. Biochem Biophys Res Commun 288:275-279 (Pubitemid 32999758)
25. Garrett IR, Boyce BF, Oreffo RO, Bonewald L, Poser J, Mundy GR (1996) Oxygen-derived free radicals stimulate osteoclastic bone resorption in rodent bone in vitro and in vivo. J Clin Invest 85:632-639
26. Devaraj S, Jialal I (2005) α-Tocopherol decreases tumor necrosis factor-α mRNA and protein from activated human monocytes by inhibition of 5-lipoxygenase. Free Radic Biol Med 38:1212-1220 (Pubitemid 40445538)
27. Krishnan V, Bryant HU, Macdougald OA (2006) Regulation of bone mass by Wnt signaling. J Clin Invest 116:1202-1209
28. Almeida M, Han L, Martin-Millan M, O'Brien CA, Manolagas SC (2007) Oxidative stress antagonizes Wnt signaling in osteoblast precursors by diverting betacatenin from T cell factor-to forkhead box O-mediated transcription. J Biol Chem 282:27298-27305 (Pubitemid 47501978)
29. Almeida M, Han L, Martin-Millan M, Plotkin LI, Stewart SA, Roberson PK, Kousteni S, O'Brien CA, Bellido T, Parfitt AM, Weinstein RS, Jilka RL, Manolagas SC (2007) Skeletal involution by age-associated oxidative stress and its acceleration by loss of sex steroids. J Biol Chem 282:27285-27297 (Pubitemid 47501960)
30. Mehat MZ, Shuid AN, Mohamed N, Muhammad N, Soelaiman IN (2010) Beneficial effects of vitamin E isomer supplementation on static and dynamic bone histomorphometry parameters in normal male rats. J Bone Miner Metab 28:503-509
31. Kurklu M, Yildiz C, Kose O, Yurttas Y, Karacalioglu O, Serdar M, Deveci S (2011) Effect of alpha-tocopherol on bone formation during distraction osteogenesis: a rabbit model. J Orthop Traumatol 12:153-158
32. Khanduja KL, Avti PK, Kumar S, Pathania V, Pathak CM (2005) Inhibitory effect of vitamin E on proinflammatory cytokines-and endotoxin-induced nitric oxide release in alveolar macrophages. Life Sci 76:2669-2680 (Pubitemid 40404056)
33. Pathania V, Syal N, Pathak CM, Khanduja KL (1999) Vitamin E suppresses the induction of reactive oxygen species release by lipopolysaccharide, interleukin-1β and tumor necrosis factor-α in rat alveolar macrophages. J Nutr Sci Vitaminol 45:675-686 (Pubitemid 30141294)
34. Chuin A, Labonté M, Tessier D, Khalil A, Bobeuf F, Doyon CY, Rieth N, Dionne IJ (2009) Effect of antioxidants combined to resistance training on BMD in elderly women: a pilot study. Osteoporos Int 20:1253-1258
35. Fujita K, Iwasaki M, Ochi H, Fukuda T, Ma C, Miyamoto T, Takitani K, Negishi-Koga T, Sunamura S, Kodama T, Takayanagi H, Tamai H, Kato S, Arai H, Shinomiya K, Itoh H, Okawa A, Takeda S (2012) Vitamin E decreases bone mass by stimulating osteoclast fusion. Nat Med 18:589-594
36. Roodman GD (2012) Vitamin E: good for the heart, bad for the bones? Nat Med 18:491-492