The role of α-tocopherol in motor hypofunction with aging in α-tocopherol transfer protein knockout mice as assessed by oxidative stress biomarkers

Journal of Nutritional Biochemistry

Volumn 21, Issue 1, 2010, Pages 66-76

  Yoshida, Yasukazu ^a   Itoh, Nanako ^a   Hayakawa, Mieko ^a   Habuchi, Yoko ^a   Saito, Yoshiro ^a   Tsukamoto, Yoshitane ^b   Cynshi, Osamu ^c   Jishage, Kou ichi ^c   Arai, Hiroyuki ^d   Niki, Etsuo ^a  

^a NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY AIST   (Japan)

^b HYOGO COLLEGE OF MEDICINE   (Japan)

^c CHUGAI PHARMACEUTICAL CO LTD   (Japan)

^d UNIVERSITY OF TOKYO   (Japan)

Author keywords

Aging; Lipid peroxidation; Motor activity; Stereoisomer ratio; Total hydroxyoctadecadienoic acid (tHODE)

Indexed keywords

8 ISOPROSTAGLANDIN F2 ALPHA; ALPHA TOCOPHEROL; ALPHA TOCOPHEROL TRANSFER PROTEIN; BIOLOGICAL MARKER; CARRIER PROTEIN; STEARIC ACID DERIVATIVE; UNCLASSIFIED DRUG;

AGING; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD LEVEL; BRAIN LEVEL; CONTROLLED STUDY; DIETARY INTAKE; FEMALE; FOOD COMPOSITION; LIPID OXIDATION; LIVER LEVEL; MALE; MOTOR ACTIVITY; MOTOR DYSFUNCTION; MOTOR PERFORMANCE; MOUSE; NONHUMAN; OXIDATIVE STRESS; STEREOISOMERISM;

AGING; ALPHA-TOCOPHEROL; ANIMALS; ASCORBIC ACID; BIOLOGICAL MARKERS; BRAIN CHEMISTRY; CARRIER PROTEINS; DINOPROST; FATTY ACIDS, UNSATURATED; FEMALE; LIPID PEROXIDATION; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MOTOR ACTIVITY; OXIDATIVE STRESS; SPECIFIC PATHOGEN-FREE ORGANISMS; STEREOISOMERISM; THIOBARBITURIC ACID REACTIVE SUBSTANCES; UBIQUINONE; VITAMIN E DEFICIENCY;

MUS;

EID: 71749098399     PISSN: 09552863     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jnutbio.2008.10.006     Document Type: Article

References (28)

1. Leonarduzzi G., Arkan M.C., Basaga H., Chiarpotto E., Sevanian A., and Poli G. Lipid oxidation products in cell signaling. Free Radic Biol Med 28 (2000) 1370-1378
2. Tang D.G., La E., Kern J., and Kehrer J.P. Fatty acid oxidation and signaling in apoptosis. Biol Chem 383 (2002) 425-442
3. Niki E., Yoshida Y., Saito Y., and Noguchi N. Lipid peroxidation: mechanisms, inhibition, and biological effects. Biochem Biophys Res Commun 338 (2005) 668-676
4. Chen Z.H., Yoshida Y., Saito Y., Noguchi N., and Niki E. Adaptive response induced by lipid peroxidation products in cell cultures. FEBS Lett 580 (2006) 479-483
5. Chen Z.H., Yoshida Y., Saito Y., Sekine A., Noguchi N., and Niki E. Induction of adaptive response and enhancement of PC12 cell tolerance by 7-hydroxycholesterol and 15-deoxy-delta12,14-prostaglandin J2 through up-regulation of cellular glutathione via different mechanisms. J Biol Chem 281 (2006) 14440-14445
6. Traber M.G., and Atkinson J. Vitamin E, antioxidant and nothing more. Free Radic Biol Med 43 (2007) 4-15
7. Azzi A. Molecular mechanism of α-tocopherol action. Free Radic Biol Med 43 (2007) 16-21
8. Roberts II L.J., Oates J.A., Linton M.F., Fazio S., Meador B.P., Gross M.D., et al. The relationship between dose of vitamin E and suppression of oxidative stress in humans. Free Radic Biol Med 43 (2007) 1388-1393
9. Terasawa Y., Ladha Z., Leonard S.W., Morrow J.D., Newland D., Sanan D., et al. Increased atherosclerosis in hyperlipidemic mice deficient in α-tocopherol transfer protein and vitamin E. Proc Natl Acad Sci U S A 97 (2000) 13830-13834
10. Yoshida Y., Hayakawa M., Itoh N., Habuchi Y., Inoue R., Chen Z.H., et al. Antioxidant effects of 2,3-dihydro-5-hydroxy-4,6-di-tert-butyl-2,2-dipentylbenzofuran and α-tocopherol in hyperlipidemic mice as evaluated by hydroxyoctadecadienoic acid and 7-hydroxycholesterol. Biochem Pharmacol 74 (2007) 1010-1019
11. Girotti A.W. Lipid hydroperoxide generation, turnover, and effector action in biological systems. J Lipid Res 39 (1998) 1529-1542
12. Yoshida Y., and Niki E. Detection of lipid peroxidation in vivo: total hydroxyoctadecadienoic acid and 7-hydroxycholesterol as oxidative stress marker. Free Rad Res 38 (2004) 787-794
13. Yoshida Y., Hayakawa M., and Niki E. Hydroxyoctadecadienoic acid as free radical-induced oxidative stress marker in vivo. BioFactors 24 (2005) 7-15
14. Yoshida Y., Itoh N., Hayakawa M., Piga R., Cynshi O., Jishage K., et al. Lipid peroxidation induced by carbon tetrachloride and its inhibition by antioxidant as evaluated by an oxidative stress marker, HODE. Toxicol Appl Pharmacol 208 (2005) 87-97
15. Yoshida Y., Itoh N., Hayakawa M., Habuchi Y., Inoue R., Chen Z.H., et al. Lipid peroxidation in mice fed choline-deficient diet and its inhibition by antioxidants as evaluated by an oxidative stress marker. HODE Nutr 22 (2006) 303-311
16. Yoshida Y., and Niki E. Review: bio-markers of lipid peroxidation in vivo; hydroxyoctadecadienoic acid and hydroxycholesterol. BioFactors 27 (2006) 195-202
17. Yoshida Y., Hayakawa M., Habuchi Y., and Niki E. Evaluation of the dietary effects of coenzyme Q in vivo by the oxidative stress marker, hydroxyoctadecadienoic acid and its stereoisomer ratio. Biochim Biophys Acta 1760 (2006) 1559-1568
18. Yoshida Y., Saito Y., Hayakawa M., Habuchi Y., Imai Y., Sawai Y., et al. Levels of lipid peroxidation in human plasma and erythrocytes: comparison between fatty acids and cholesterol. Lipids 42 (2007) 439-449
19. Yoshida Y., Hayakawa M., Habuchi Y., Itoh N., and Niki E. Evaluation of lipophilic antioxidant efficacy in vivo by the biomarkers hydroxyoctadecadienoic acid and isoprostane. Lipids 42 (2007) 463-472
20. Yokota T., Igarashi K., Uchihara T., Jishage K., Tomita H., Inaba A., et al. Delayed-onset ataxia in mice lacking α-tocopherol transfer protein: model for neuronal degeneration caused by chronic oxidative stress. Proc Natl Acad Sci U S A 98 (2001) 15185-15190
21. Gohil K., Godzdanker R., O'Roark E., Schock B.C., Kaini R.R., Packer L., et al. α-Tocopherol transfer protein deficiency in mice causes multi-organ deregulation of gene networks and behavioral deficits with age. Ann NY Acad Sci 1031 (2004) 109-126
22. Chen Z.H., Saito Y., Yoshida Y., Sekine A., Noguchi N., and Niki E. 4-Hydroxynonenal induced adaptive response and enhances PC12 cell tolerance primarily through induction of thioredoxin reductase 1 via activation of Nrf2. J Biol Chem 280 (2005) 41921-41927
23. Moore K., and Roberts L.J. Measurements of lipid peroxidation. Free Rad Res 28 (1998) 659-671
24. Basu S. Isoprostanes: novel bioactive products of lipid peroxidation. Free Rad Res. 38 (2004) 105-122
25. Cyrus T., Pratico D., Zhao L., Witztum J.L., Rader D.J., Rokach J., et al. Absence of 12/15-lipoxygenase expression decreases lipid peroxidation and atherogenesis in apolipoprotein E-deficient mice. Circulation 103 (2001) 2277-2282
26. Suarna C., Wu B.J., Choy K., Mori T., Croft K., Cynshi O., et al. Protective effect of vitamin E supplements on experimental atherosclerosis is modest and depends on preexisting vitamin E deficiency. Free Radic Biol Med 41 (2006) 722-730
27. Porter N.A., Caldwell S.E., and Mills K.A. Mechanisms of free radical oxidation of unsaturated lipids. Lipids 30 (1995) 277-290
28. Niki E. Antioxidants and atherosclerosis. Biochem Soc Trans 32 (2004) 156-159