Esophagoprotection mediated by exogenous and endogenous melatonin in an experimental model of reflux esophagitis

Journal of Pineal Research

Volumn 55, Issue 1, 2013, Pages 46-57

  Konturek, Peter C ^a   Brzozowska, Iwona ^b   Targosz, Aneta ^b   Pawlik, Michal ^b   Kania, Joanna ^b   Hess, Thomas ^a   Kwiecien, Slawomir ^b   Konturek, Stanislaw J ^b   Reiter, Russel J ^c   Brzozowski, Tomasz ^b  

^a Teaching Hospital of the University of Jena   (Germany)

^b JAGIELLONIAN UNIVERSITY MEDICAL COLLEGE   (Poland)

^c Mays Cancer Center at UT Health San Antonio   (United States)

Author keywords

Capsaicin sensitive afferent nerves; L tryptophan; Melatonin; Nitric oxide; Pineal gland; Proinflammatory cytokines; Reflux esophagitis; Stress induced gastric lesions

Indexed keywords

ARGININE; CALCITONIN GENE RELATED PEPTIDE; CAPSAICIN; INTERLEUKIN 1BETA; LUZINDOLE; MELATONIN; MELATONIN 2 RECEPTOR; MESSENGER RNA; NITRIC OXIDE; PANTOPRAZOLE; RANITIDINE; TRYPTOPHAN; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG ACTIVITY; EDEMA; ESOPHAGOPROTECTION; ESOPHAGUS MUCOSA; FORESTOMACH; GENE EXPRESSION REGULATION; HORMONE BLOOD LEVEL; HYPEREMIA; LIGATION; MALE; NEUTROPHIL; NONHUMAN; PINEALECTOMY; PROTECTION; PROTEIN BLOOD LEVEL; PYLORUS; RAT; REFLUX ESOPHAGITIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SENSORY NERVE; TISSUE BLOOD FLOW; UPREGULATION;

CAPSAICIN-SENSITIVE AFFERENT NERVES; L-TRYPTOPHAN; MELATONIN; NITRIC OXIDE; PINEAL GLAND; PROINFLAMMATORY CYTOKINES; REFLUX ESOPHAGITIS; STRESS-INDUCED GASTRIC LESIONS;

ANALYSIS OF VARIANCE; ANIMALS; ARGININE; CAPSAICIN; DIGESTIVE SYSTEM SURGICAL PROCEDURES; DISEASE MODELS, ANIMAL; ESOPHAGITIS, PEPTIC; ESOPHAGUS; MALE; MELATONIN; MUCOUS MEMBRANE; NITRIC OXIDE; PINEAL GLAND; PROTECTIVE AGENTS; RATS; RATS, WISTAR; TRYPTOPHAN;

EID: 84885184058     PISSN: 07423098     EISSN: 1600079X     Source Type: Journal    
DOI: 10.1111/jpi.12048     Document Type: Article

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