The effect of STAT3 inhibition on status epilepticus and subsequent spontaneous seizures in the pilocarpine model of acquired epilepsy

Neurobiology of Disease

Volumn 62, Issue , 2014, Pages 73-85

  Grabenstatter, H L ^a   Del Angel, Y Cruz ^a   Carlsen, J ^a   Wempe, M F ^b   White, A M ^a   Cogswell, M ^c   Russek, S J ^c   Brooks Kayal, A R ^a,b,d,e  

^a Children's Hospital Colorado   (United States)

^b UNIVERSITY OF COLORADO   (United States)

^c BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

^e CHILDREN S HOSPITAL COLORADO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR ALPHA1; ANTICONVULSIVE AGENT; CYCLIN D1; DIAZEPAM; JANUS KINASE; JANUS KINASE INHIBITOR; MESSENGER RNA; PILOCARPINE; PROTEIN BCL XL; PROTEIN INHIBITOR; PROTEIN MCL 1; STAT3 PROTEIN; UNCLASSIFIED DRUG; WP 1066;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BCL XL GENE; BIOLOGICAL MONITORING; CELL CYCLE PROGRESSION; CELL DEATH; CELL SURVIVAL; CONTROLLED STUDY; CYCLIN D1 GENE; DISEASE ACTIVITY; DISEASE COURSE; DISEASE SEVERITY; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG HALF LIFE; DRUG MECHANISM; DRUG METABOLISM; DRUG TISSUE LEVEL; DRUG TRANSPORT; ELECTROENCEPHALOGRAPHY; ENZYME INHIBITION; EPILEPTIC STATE; EPILEPTOGENESIS; GABRA1 GENE; GENE; GENE CONTROL; ICER GENE; MCL 1 GENE; NONHUMAN; ONCOGENE C MYC; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN TARGETING; RAT; SEIZURE; TRANSCRIPTION REGULATION;

B-CELL LYMPHOMA 2; B-CELL LYMPHOMA-EXTRA LARGE; BCL-2; BCL-XL; C-MYC; CELLULAR REGULATORY GENE THAT CODES FOR A TRANSCRIPTION FACTOR; CYCLIN D1; G1/S-SPECIFIC CYCLIN-D1 (ENCODED BY CCND1); ICER; INDUCED MYELOID LEUKEMIA CELL DIFFERENTIATION PROTEIN; INDUCIBLE CAMP EARLY REPRESSOR PROTEIN; JAK; JANUS KINASE; MCL-1; SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION; STAT; VASCULAR ENDOTHELIAL GROWTH FACTOR; VEGF;

ANIMALS; BRAIN; CELL DEATH; DENTATE GYRUS; DISEASE MODELS, ANIMAL; ELECTROENCEPHALOGRAPHY; HIPPOCAMPUS; PHOSPHORYLATION; PILOCARPINE; PYRIDINES; RATS; RATS, SPRAGUE-DAWLEY; SEIZURES; SIGNAL TRANSDUCTION; STAT3 TRANSCRIPTION FACTOR; STATUS EPILEPTICUS; TYRPHOSTINS;

EID: 84885170260     PISSN: 09699961     EISSN: 1095953X     Source Type: Journal    
DOI: 10.1016/j.nbd.2013.09.003     Document Type: Article

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