Mcl-1 is a key regulator of apoptosis during CNS development and after DNA damage

Journal of Neuroscience

Volumn 28, Issue 24, 2008, Pages 6068-6078

  Arbour, Nicole ^a   Vanderluit, Jacqueline L ^a,e   Le Grand, J Nicole ^a   Jahani Asl, Arezu ^a   Ruzhynsky, Vladimir A ^a   Cheung, Eric C C ^a   Kelly, Melissa A ^a   MacKenzie, Alexander E ^b   Park, David S ^a   Opferman, Joseph T ^c   Slack, Ruth S ^a,d  

^a OTTAWA HOSPITAL RESEARCH INSTITUTE   (Canada)

^b CHILDREN S HOSPITAL OF EASTERN ONTARIO   (Canada)

^c ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^d UNIVERSITY OF OTTAWA   (Canada)

^e MEMORIAL UNIVERSITY OF NEWFOUNDLAND   (Canada)

Author keywords

Apoptosis; Cell death; Development; Neurogenesis; Neuron; Neuronal progenitors

Indexed keywords

CASPASE 3; MESSENGER RNA; PROTEIN BCL 2; PROTEIN MCL 1; BETA3 TUBULIN, MOUSE; GREEN FLUORESCENT PROTEIN; MYELOID CELL LEUKEMIA SEQUENCE 1 PROTEIN; NERVE PROTEIN; TUBULIN;

APOPTOSIS; ARTICLE; AUTONOMIC NERVOUS SYSTEM; BRAIN VENTRICLE; CELL DEATH; CELL DIFFERENTIATION; CELL MIGRATION; CENTRAL NERVOUS SYSTEM; CHEMICAL LABELING; DNA DAMAGE; IN VITRO STUDY; MOUSE; NERVE CELL; NERVOUS SYSTEM DEVELOPMENT; NONHUMAN; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN FUNCTION; REGULATORY MECHANISM; STEM CELL; SURVIVAL RATE; AGE; ANIMAL; CELL CULTURE; CELL MOTION; CELL PROLIFERATION; CYTOLOGY; EMBRYO (ANATOMY); GENE EXPRESSION REGULATION; GENETIC TRANSFECTION; GENETICS; METABOLISM; METHODOLOGY; MUTATION; PHYSIOLOGY; PRENATAL DEVELOPMENT; TRANSGENIC MOUSE;

AGE FACTORS; ANIMALS; APOPTOSIS; CASPASE 3; CELL DIFFERENTIATION; CELL MOVEMENT; CELL PROLIFERATION; CELLS, CULTURED; CENTRAL NERVOUS SYSTEM; DNA DAMAGE; EMBRYO, MAMMALIAN; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GREEN FLUORESCENT PROTEINS; MICE; MICE, TRANSGENIC; MUTATION; NERVE TISSUE PROTEINS; NEURONS; PROTO-ONCOGENE PROTEINS C-BCL-2; STEM CELLS; TRANSFECTION; TUBULIN;

EID: 46749143782     PISSN: 02706474     EISSN: 02706474     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.4940-07.2008     Document Type: Article

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