Behavior of human cytochromes P450 on lipid membranes

Journal of Physical Chemistry B

Volumn 117, Issue 39, 2013, Pages 11556-11564

  Berka, Karel ^a   Paloncýová, Markéta ^a   Anzenbacher, Pavel ^a   Otyepka, Michal ^a  

^a PALACKÝ UNIVERSITY   (Czech Republic)

Author keywords

[No Author keywords available]

Indexed keywords

BEHAVIORAL RESEARCH; ENZYMES; INTERFACES (MATERIALS); LIPID BILAYERS; MOLECULAR DYNAMICS;

CATALYTIC DOMAINS; HUMAN CYTOCHROMES P450; MEMBRANE-WATER INTERFACE; MOLECULAR DYNAMICS SIMULATIONS; NONPOLAR SUBSTRATES; PARTIALLY IMMERSED; POLAR SUBSTRATES; SUBSTRATE POSITIONS;

SUBSTRATES;

1,2 OLEOYLPHOSPHATIDYLCHOLINE; 1,2-OLEOYLPHOSPHATIDYLCHOLINE; COUMARIN 7 HYDROXYLASE; COUMARIN 7-HYDROXYLASE; CYP1A2 PROTEIN, HUMAN; CYP2C9 PROTEIN, HUMAN; CYP3A4 PROTEIN, HUMAN; CYTOCHROME P450; CYTOCHROME P450 1A2; CYTOCHROME P450 3A; HEME; PHOSPHATIDYLCHOLINE; SOLVENT; UNSPECIFIC MONOOXYGENASE; WATER;

ARTICLE; CHEMISTRY; COMPARATIVE STUDY; ENZYME ACTIVE SITE; HUMAN; LIPID BILAYER; MOLECULAR DYNAMICS; PROTEIN CONFORMATION; TIME;

ARYL HYDROCARBON HYDROXYLASES; CATALYTIC DOMAIN; CYTOCHROME P-450 CYP1A2; CYTOCHROME P-450 CYP3A; CYTOCHROME P-450 ENZYME SYSTEM; HEME; HUMANS; LIPID BILAYERS; MOLECULAR DYNAMICS SIMULATION; PHOSPHATIDYLCHOLINES; PROTEIN CONFORMATION; SOLVENTS; TIME FACTORS; WATER;

EID: 84885112149     PISSN: 15206106     EISSN: 15205207     Source Type: Journal    
DOI: 10.1021/jp4059559     Document Type: Article

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