Characterizing the membrane-bound state of cytochrome P450 3A4: Structure, depth of insertion, and orientation

Journal of the American Chemical Society

Volumn 135, Issue 23, 2013, Pages 8542-8551

  Baylon, Javier L ^a   Lenov, Ivan L ^a   Sligar, Stephen G ^a   Tajkhorshid, Emad ^a  

^a UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CONFORMATIONAL CHANGE; CRYSTALLOGRAPHIC STRUCTURE; CYTOCHROME P450-3A4; FULL-LENGTH ENZYMES; MEMBRANE ORIENTATION; SIMULATION APPROACH; STRUCTURAL INFORMATION; TRANSMEMBRANE HELICES;

COMPUTER SIMULATION; ENZYMES; PROTEINS;

MEMBRANES;

CYTOCHROME P450 3A4; LIPID;

ARTICLE; ENZYME STRUCTURE; HIGHLY MOBILE MEMBRANE MIMETIC; LINEAR DICHROISM; MEMBRANE; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN STRUCTURE; SIMULATION;

CYTOCHROME P-450 CYP3A; HUMANS; MEMBRANE LIPIDS; MODELS, MOLECULAR; MOLECULAR DYNAMICS SIMULATION; MOLECULAR STRUCTURE;

EID: 84878953386     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja4003525     Document Type: Article

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