Common gating of both CLC transporter subunits underlies voltage-dependent activation of the 2Cl-/1H+ exchanger ClC-7/Ostm1

Journal of Biological Chemistry

Volumn 288, Issue 40, 2013, Pages 28611-28619

  Ludwig, Carmen F ^a,b   Ullrich, Florian ^a,b   Leisle, Lilia ^a,b,d   Stauber, Tobias ^a,b   Jentsch, Thomas J ^a,b,c  

^a LEIBNIZ INSTITUT FÜR MOLEKULARE PHARMAKOLOGIE   (Germany)

^b MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

^c CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^d UNIVERSITY OF IOWA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

C TERMINUS; CYTOPLASMIC DOMAINS; NONCOVALENT BINDING;

CHLORINE COMPOUNDS;

BINDING ENERGY;

CLC 7 PROTEIN; CYSTATHIONINE BETA SYNTHASE; ION CHANNEL; OSTM1 PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BETA CHAIN; CARBOXY TERMINAL SEQUENCE; CELL MEMBRANE; CHANNEL GATING; CONTROLLED STUDY; CYTOPLASM; FEMALE; NONHUMAN; OOCYTE; POINT MUTATION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN STRUCTURE; PROTEIN SUBUNIT; VOLTAGE CLAMP; XENOPUS LAEVIS;

ALBERS-SCHÖNBERG DISEASE; ANION TRANSPORT; ANTIPORT; CHLORIDE TRANSPORT; GATING; ION CHANNELS; LYSOSOMAL STORAGE DISEASE; SPLIT-CHANNEL;

AMINO ACID SEQUENCE; ANIMALS; ANTIPORTERS; CHLORIDE CHANNELS; CYSTATHIONINE BETA-SYNTHASE; HUMANS; ION CHANNEL GATING; IONS; KINETICS; MEMBRANE PROTEINS; MOLECULAR SEQUENCE DATA; MUTAGENESIS, INSERTIONAL; MUTATION; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, TERTIARY; PROTEIN SUBUNITS; UBIQUITIN-PROTEIN LIGASES; XENOPUS LAEVIS;

EID: 84885103533     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.509364     Document Type: Article

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