Inter-subunit communication and fast gate integrity are important for common gating in hClC-1

International Journal of Biochemistry and Cell Biology

Volumn 42, Issue 7, 2010, Pages 1182-1188

  Cederholm, Jennie M ^a   Rychkov, Grigori Y ^b   Bagley, Christopher J ^b,c   Bretag, Allan H ^a  

^a UNIVERSITY OF SOUTH AUSTRALIA   (Australia)

^b UNIVERSITY OF ADELAIDE   (Australia)

^c HANSON INSTITUTE   (Australia)

Author keywords

Common gating; Dimerisation interface; Glutamate fast gate; Human skeletal muscle chloride channel hClC 1; Residue volume

Indexed keywords

CHLORIDE CHANNEL; PROTEIN CLC1; UNCLASSIFIED DRUG; CLC-1 CHANNEL; MUTANT PROTEIN; PROTEIN SUBUNIT;

ARTICLE; CELL STRAIN HEK293; CHANNEL GATING; COMPUTER MODEL; CONTROLLED STUDY; CRYSTAL STRUCTURE; CYTOPLASM; ELECTROPHYSIOLOGY; GENE MUTATION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; MOLECULAR MODEL; MUTANT; PATCH CLAMP; PROTEIN FAMILY; SITE DIRECTED MUTAGENESIS; AMINO ACID SUBSTITUTION; CELL LINE; GENETICS; METABOLISM; PROTEIN SUBUNIT;

AMINO ACID SUBSTITUTION; CELL LINE; CHLORIDE CHANNELS; HUMANS; ION CHANNEL GATING; MUTANT PROTEINS; PROTEIN SUBUNITS;

BACTERIA (MICROORGANISMS);

EID: 77953541008     PISSN: 13572725     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biocel.2010.04.004     Document Type: Article

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