Ursolic acid inhibits colorectal cancer angiogenesis through suppression of multiple signaling pathways

International Journal of Oncology

Volumn 43, Issue 5, 2013, Pages 1666-1674

  Lin, Jiumao ^a   Chen, Youqin ^b   Wei, Lihui ^a   Hong, Zhenfeng ^a   Sferra, Thomas J ^b   Peng, Jun ^a  

^a FUJIAN UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

^b CASE WESTERN RESERVE UNIVERSITY   (United States)

Author keywords

Signal pathway; Tumor angiogenesis; Ursolic acid

Indexed keywords

FIBROBLAST GROWTH FACTOR 2; PROTEIN KINASE B; SONIC HEDGEHOG PROTEIN; STAT3 PROTEIN; URSOLIC ACID; VASCULOTROPIN A;

ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIANGIOGENIC ACTIVITY; ANTINEOPLASTIC ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; ARTICLE; CANCER INHIBITION; CELL MIGRATION; CELL PROLIFERATION; COLON CARCINOMA; COLORECTAL CANCER; CONTROLLED STUDY; DRUG EFFICACY; DRUG MECHANISM; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MALE; MOUSE; NONHUMAN; PHASE 1 CLINICAL TRIAL; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; TUMOR XENOGRAFT; UMBILICAL VEIN ENDOTHELIAL CELL;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; BLOTTING, WESTERN; CELL MOVEMENT; CELL PROLIFERATION; CHICK EMBRYO; CHORIOALLANTOIC MEMBRANE; COLORECTAL NEOPLASMS; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; IMMUNOENZYME TECHNIQUES; MALE; MICE; MICE, INBRED BALB C; MICE, NUDE; NEOVASCULARIZATION, PATHOLOGIC; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SIGNAL TRANSDUCTION; TRITERPENES; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84885067636     PISSN: 10196439     EISSN: 17912423     Source Type: Journal    
DOI: 10.3892/ijo.2013.2101     Document Type: Article

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