-
1
-
-
79952814836
-
Osteoarthritis year 2010 in review: pathomechanisms
-
van den Berg WB. Osteoarthritis year 2010 in review: pathomechanisms. Osteoarthritis Cartilage 2011; 19: 338-341.
-
(2011)
Osteoarthritis Cartilage
, vol.19
, pp. 338-341
-
-
van den Berg, W.B.1
-
2
-
-
0345211445
-
Purification and cloning of aggrecanase-1: a member of the ADAMTS family of proteins
-
Tortorella MD, Burn TC, Pratta MA, et al. Purification and cloning of aggrecanase-1: a member of the ADAMTS family of proteins. Science 1999; 284: 1664-1666.
-
(1999)
Science
, vol.284
, pp. 1664-1666
-
-
Tortorella, M.D.1
Burn, T.C.2
Pratta, M.A.3
-
3
-
-
4143112912
-
A disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motifs: the ADAMTS family
-
Apte SS. A disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motifs: the ADAMTS family. Int J Biochem Cell Biol 2004; 36: 981-985.
-
(2004)
Int J Biochem Cell Biol
, vol.36
, pp. 981-985
-
-
Apte, S.S.1
-
4
-
-
12144290656
-
Dose-dependent biphasic induction and transcriptional activity of nuclear factor kappa B (NF-kappa B) in EA.hy.926 endothelial cells after low-dose X-irradiation
-
Rodel F, Hantschel M, Hildebrandt G, et al. Dose-dependent biphasic induction and transcriptional activity of nuclear factor kappa B (NF-kappa B) in EA.hy.926 endothelial cells after low-dose X-irradiation. Int J Radiat Biol 2004; 80: 115-123.
-
(2004)
Int J Radiat Biol
, vol.80
, pp. 115-123
-
-
Rodel, F.1
Hantschel, M.2
Hildebrandt, G.3
-
5
-
-
0031897632
-
NF-kappa B and rel proteins: evolutionarily conserved mediators of immune responses
-
Ghosh S, May MJ, Kopp EB. NF-kappa B and rel proteins: evolutionarily conserved mediators of immune responses. Ann Rev Immunol 1998; 16: 225-260.
-
(1998)
Ann Rev Immunol
, vol.16
, pp. 225-260
-
-
Ghosh, S.1
May, M.J.2
Kopp, E.B.3
-
6
-
-
70350586944
-
Mitogen activated protein kinases: a role in inflammatory bowel disease?
-
Broom OJ, Widjaya B, Troelsen J, et al. Mitogen activated protein kinases: a role in inflammatory bowel disease? Clin Exp Immunol 2009; 158: 272-280.
-
(2009)
Clin Exp Immunol
, vol.158
, pp. 272-280
-
-
Broom, O.J.1
Widjaya, B.2
Troelsen, J.3
-
7
-
-
84871005375
-
The p38 MAPK pathway in rheumatoid arthritis: a sideways look
-
Clark AR, Dean JL. The p38 MAPK pathway in rheumatoid arthritis: a sideways look. Open Rheumatol J 2012; 6: 209-219.
-
(2012)
Open Rheumatol J
, vol.6
, pp. 209-219
-
-
Clark, A.R.1
Dean, J.L.2
-
8
-
-
0036143654
-
p38-dependent marking of inflammatory genes for increased NF-kappa B recruitment
-
Saccani S, Pantano S, Natoli G. p38-dependent marking of inflammatory genes for increased NF-kappa B recruitment. Nat Immunol 2002; 3: 69-75.
-
(2002)
Nat Immunol
, vol.3
, pp. 69-75
-
-
Saccani, S.1
Pantano, S.2
Natoli, G.3
-
9
-
-
77952705182
-
Biology and pathology of Rho GTPase, PI-3 kinase-Akt, and MAP kinase signaling pathways in chondrocytes
-
Beier F, Loeser RF. Biology and pathology of Rho GTPase, PI-3 kinase-Akt, and MAP kinase signaling pathways in chondrocytes. J Cell Biochem 2010; 110: 573-580.
-
(2010)
J Cell Biochem
, vol.110
, pp. 573-580
-
-
Beier, F.1
Loeser, R.F.2
-
10
-
-
33746257209
-
The evolution of phosphatidylinositol 3-kinases as regulators of growth and metabolism
-
Engelman JA, Luo J, Cantley LC. The evolution of phosphatidylinositol 3-kinases as regulators of growth and metabolism. Nat Rev Genetics 2006; 7: 606-619.
-
(2006)
Nat Rev Genetics
, vol.7
, pp. 606-619
-
-
Engelman, J.A.1
Luo, J.2
Cantley, L.C.3
-
11
-
-
84870984149
-
The therapeutic potential for PI3K inhibitors in autoimmune rheumatic diseases
-
Banham-Hall E, Clatworthy MR, Okkenhaug K. The therapeutic potential for PI3K inhibitors in autoimmune rheumatic diseases. Open Rheumatol J 2012; 6: 245-258.
-
(2012)
Open Rheumatol J
, vol.6
, pp. 245-258
-
-
Banham-Hall, E.1
Clatworthy, M.R.2
Okkenhaug, K.3
-
12
-
-
84867788302
-
Adenovirus-mediated overexpression of BMP-9 inhibits human osteosarcoma cell growth and migration through downregulation of the PI3K/AKT pathway
-
Li B, Yang Y, Jiang S, et al. Adenovirus-mediated overexpression of BMP-9 inhibits human osteosarcoma cell growth and migration through downregulation of the PI3K/AKT pathway. Int J Oncol 2012; 41: 1809-1819.
-
(2012)
Int J Oncol
, vol.41
, pp. 1809-1819
-
-
Li, B.1
Yang, Y.2
Jiang, S.3
-
13
-
-
33847239467
-
PI3K delta and PI3K gamma: partners in crime in inflammation in rheumatoid arthritis and beyond?
-
Rommel C, Camps M, Ji H. PI3K delta and PI3K gamma: partners in crime in inflammation in rheumatoid arthritis and beyond? Nat Rev Immunol 2007; 7: 191-201.
-
(2007)
Nat Rev Immunol
, vol.7
, pp. 191-201
-
-
Rommel, C.1
Camps, M.2
Ji, H.3
-
14
-
-
84860847334
-
Osteoarthritis: genetic factors, animal models, mechanisms, and therapies
-
Bian Q, Wang YJ, Liu SF, et al. Osteoarthritis: genetic factors, animal models, mechanisms, and therapies. Front Biosci (Elite Ed) 2012; 4: 74-100.
-
(2012)
Front Biosci (Elite Ed)
, vol.4
, pp. 74-100
-
-
Bian, Q.1
Wang, Y.J.2
Liu, S.F.3
-
15
-
-
18644370594
-
ADAMTS-9 is synergistically induced by interleukin-1 beta and tumor necrosis factor alpha in OUMS-27 chondrosarcoma cells and in human chondrocytes
-
Demircan K, Hirohata S, Nishida K, et al. ADAMTS-9 is synergistically induced by interleukin-1 beta and tumor necrosis factor alpha in OUMS-27 chondrosarcoma cells and in human chondrocytes. Arthritis Rheum 2005; 52: 1451-1460.
-
(2005)
Arthritis Rheum
, vol.52
, pp. 1451-1460
-
-
Demircan, K.1
Hirohata, S.2
Nishida, K.3
-
16
-
-
18644375615
-
Increased AP-1 and NF-kappa B activation and recruitment with the combination of the proinflammatory cytokines IL-1 beta, tumor necrosis factor alpha and IL-17 in rheumatoid synoviocytes
-
Granet C, Maslinski W, Miossec P. Increased AP-1 and NF-kappa B activation and recruitment with the combination of the proinflammatory cytokines IL-1 beta, tumor necrosis factor alpha and IL-17 in rheumatoid synoviocytes. Arthritis Res Ther 2004; 6: R190-R198.
-
(2004)
Arthritis Res Ther
, vol.6
-
-
Granet, C.1
Maslinski, W.2
Miossec, P.3
-
17
-
-
2442621078
-
Combination of the pro-inflammatory cytokines IL-1, TNF-alpha and IL-17 leads to enhanced expression and additional recruitment of AP-1 family members, Egr-1 and NF-kappa B in osteoblast-like cells
-
Granet C, Miossec P. Combination of the pro-inflammatory cytokines IL-1, TNF-alpha and IL-17 leads to enhanced expression and additional recruitment of AP-1 family members, Egr-1 and NF-kappa B in osteoblast-like cells. Cytokine 2004; 26: 169-177.
-
(2004)
Cytokine
, vol.26
, pp. 169-177
-
-
Granet, C.1
Miossec, P.2
-
18
-
-
0036252640
-
Inhibition of interleukin-1-stimulated MAP kinases, activating protein-1 (AP-1) and nuclear factor kappa B (NF-kappa B) transcription factors down-regulates matrix metalloproteinase gene expression in articular chondrocytes
-
Liacini A, Sylvester J, Li WQ, et al. Inhibition of interleukin-1-stimulated MAP kinases, activating protein-1 (AP-1) and nuclear factor kappa B (NF-kappa B) transcription factors down-regulates matrix metalloproteinase gene expression in articular chondrocytes. Matrix Biol 2002; 21: 251-262.
-
(2002)
Matrix Biol
, vol.21
, pp. 251-262
-
-
Liacini, A.1
Sylvester, J.2
Li, W.Q.3
-
19
-
-
0030615201
-
Mechanisms of disease - Nuclear factor-kappa b - A pivotal transcription factor in chronic inflammatory diseases
-
Barnes PJ, Larin M. Mechanisms of disease - Nuclear factor-kappa b - A pivotal transcription factor in chronic inflammatory diseases. N Engl J Med 1997; 336: 1066-1071.
-
(1997)
N Engl J Med
, vol.336
, pp. 1066-1071
-
-
Barnes, P.J.1
Larin, M.2
-
20
-
-
80055024288
-
ADAMTS-4 and ADAMTS-5: key enzymes in osteoarthritis
-
Verma P, Dalal K. ADAMTS-4 and ADAMTS-5: key enzymes in osteoarthritis. J Cell Biochem 2011; 112: 3507-3514.
-
(2011)
J Cell Biochem
, vol.112
, pp. 3507-3514
-
-
Verma, P.1
Dalal, K.2
-
21
-
-
2942541805
-
The carboxyl-terminal half region of ADAMTS-1 suppresses both tumorigenicity and experimental tumor metastatic potential
-
Kuno K, Bannai K, Hakozaki M, et al. The carboxyl-terminal half region of ADAMTS-1 suppresses both tumorigenicity and experimental tumor metastatic potential. Biochem Biophys Res Commun 2004; 319: 1327-1333.
-
(2004)
Biochem Biophys Res Commun
, vol.319
, pp. 1327-1333
-
-
Kuno, K.1
Bannai, K.2
Hakozaki, M.3
-
22
-
-
79151483757
-
Regulation of mechanical stress-induced MMP-13 and ADAMTS-5 expression by RUNX-2 transcriptional factor in SW1353 chondrocyte-like cells
-
Tetsunaga T, Nishida K, Furumatsu T, et al. Regulation of mechanical stress-induced MMP-13 and ADAMTS-5 expression by RUNX-2 transcriptional factor in SW1353 chondrocyte-like cells. Osteoarthritis Cartilage 2011; 19: 222-232.
-
(2011)
Osteoarthritis Cartilage
, vol.19
, pp. 222-232
-
-
Tetsunaga, T.1
Nishida, K.2
Furumatsu, T.3
-
23
-
-
33745623947
-
Differential regulation of cytokine-induced MMP-1 and MMP-13 expression by p38 kinase inhibitors in human chondrosarcoma cells: potential role of Runx2 in mediating p38 effects
-
Pei Y, Harvey A, Yu XP, et al. Differential regulation of cytokine-induced MMP-1 and MMP-13 expression by p38 kinase inhibitors in human chondrosarcoma cells: potential role of Runx2 in mediating p38 effects. Osteoarthritis Cartilage 2006; 14: 749-758.
-
(2006)
Osteoarthritis Cartilage
, vol.14
, pp. 749-758
-
-
Pei, Y.1
Harvey, A.2
Yu, X.P.3
-
24
-
-
0037811204
-
Induction of matrix metalloproteinase-13 gene expression by TNF-alpha is mediated by MAP kinases, AP-1, and NF-kappaB transcription factors in articular chondrocytes
-
Liacini A, Sylvester J, Li WQ, et al. Induction of matrix metalloproteinase-13 gene expression by TNF-alpha is mediated by MAP kinases, AP-1, and NF-kappaB transcription factors in articular chondrocytes. Exp Cell Res 2003; 288: 208-217.
-
(2003)
Exp Cell Res
, vol.288
, pp. 208-217
-
-
Liacini, A.1
Sylvester, J.2
Li, W.Q.3
-
25
-
-
0015785965
-
Pharmacology of diferuloyl methane (curcumin), a non-steroidal anti-inflammatory agent
-
Srimal RC, Dhawan BN. Pharmacology of diferuloyl methane (curcumin), a non-steroidal anti-inflammatory agent. J Pharm Pharmacol 1973; 25: 447-452.
-
(1973)
J Pharm Pharmacol
, vol.25
, pp. 447-452
-
-
Srimal, R.C.1
Dhawan, B.N.2
-
26
-
-
28344447838
-
Curcumin protects human chondrocytes from IL-l1beta-induced inhibition of collagen type II and beta1-integrin expression and activation of caspase-3: an immunomorphological study
-
Shakibaei M, Schulze-Tanzil G, John T, et al. Curcumin protects human chondrocytes from IL-l1beta-induced inhibition of collagen type II and beta1-integrin expression and activation of caspase-3: an immunomorphological study. Ann Anat 2005; 187: 487-497.
-
(2005)
Ann Anat
, vol.187
, pp. 487-497
-
-
Shakibaei, M.1
Schulze-Tanzil, G.2
John, T.3
-
28
-
-
78651458938
-
Bradykinin and B(2) receptor antagonism in rat and human articular chondrocytes
-
Meini S, Cucchi P, Catalani C, et al. Bradykinin and B(2) receptor antagonism in rat and human articular chondrocytes. Br J Pharmacol 2011; 162: 611-622.
-
(2011)
Br J Pharmacol
, vol.162
, pp. 611-622
-
-
Meini, S.1
Cucchi, P.2
Catalani, C.3
|