A disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motifs: The ADAMTS family

International Journal of Biochemistry and Cell Biology

Volumn 36, Issue 6, 2004, Pages 981-985

  Apte, Suneel S ^a  

^a LERNER RESEARCH INSTITUTE   (United States)

Author keywords

A disintegrin and metalloprotease domain; A disintegrin like and metalloprotease domain (reprolysin type) with thrombospondin type 1 motifs; a.a.; ADAM; ADAMTS; Amino acid; Matrix metalloprotease; Metalloprotease; MMP; Thrombospondin type 1 repeat; TSR

Indexed keywords

A DISINTEGRIN LIKE AND METALLOPROTEASE DOMAIN (REPROLYSIN TYPE) WITH THROMBOSPONDIN TYPE 1 MOTIF; A DISINTEGRIN LIKE AND METALLOPROTEASE DOMAIN (REPROLYSIN TYPE) WITH THROMBOSPONDIN TYPE 1 MOTIF 1; A DISINTEGRIN LIKE AND METALLOPROTEASE DOMAIN (REPROLYSIN TYPE) WITH THROMBOSPONDIN TYPE 1 MOTIF 14; A DISINTEGRIN LIKE AND METALLOPROTEASE DOMAIN (REPROLYSIN TYPE) WITH THROMBOSPONDIN TYPE 1 MOTIF 3; A DISINTEGRIN LIKE AND METALLOPROTEASE DOMAIN (REPROLYSIN TYPE) WITH THROMBOSPONDIN TYPE 1 MOTIF 8; AGGRECANASE; ANGIOGENESIS INHIBITOR; BREVICAN; ENZYME PRECURSOR; GLYCOSAMINOGLYCAN; MEMBRANE PROTEIN; METALLOPROTEINASE INHIBITOR; PROCOLLAGEN; PROTEINASE; TISSUE INHIBITOR OF METALLOPROTEINASE 3; UNCLASSIFIED DRUG; VON WILLEBRAND FACTOR;

AMINO ACID SEQUENCE; ARTHRITIS; BLOOD CLOTTING DISORDER; BRAIN TUMOR; CANCER; CARBOXY TERMINAL SEQUENCE; CATALYSIS; CELL MIGRATION; CLINICAL TRIAL; EHLERS DANLOS SYNDROME; GENE MUTATION; HUMAN; NONHUMAN; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN MOTIF; PROTEIN SECRETION; PROTEIN STRUCTURE; PROTEIN SYNTHESIS; PROTEIN TARGETING; REVIEW; SIDE EFFECT; SKIN DISEASE; THROMBOCYTOPENIC PURPURA;

EID: 4143112912     PISSN: 13572725     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biocel.2004.01.014     Document Type: Short Survey

References (18)

1. Blelloch R., Anna-Arriola S.S., Gao D., Li Y., Hodgkin J., Kimble J. The gon-1 gene is required for gonadal morphogenesis in Caenorhabditis elegans. Developmental Biology. 216:1999;382-393.
2. Colige A., Sieron A.L., Li S.W., Schwarze U., Petty E., Wertelecki W., Wilcox W., Krakow D., Cohn D.H., Reardon W., Byers P.H., Lapiere C.M., Prockop D.J., Nusgens B.V. Human Ehlers-Danlos syndrome type VII C and bovine dermatosparaxis are caused by mutations in the procollagen I N-proteinase gene. American Journal of Human Genetics. 65:1999;308-317.
3. Fernandes R.J., Hirohata S., Engle J.M., Colige A., Cohn D.H., Eyre D.R., Apte S.S. Procollagen II amino propeptide processing by ADAMTS-3. Insights on dermatosparaxis. Journal of Biological Chemistry. 276:2001;31502-31509.
4. Gao G., Westling J., Thompson V.P., Howell T.D., Gottschall P.E., Sandy J.D. Activation of the proteolytic activity of ADAMTS4 (aggrecanase-1) by C-terminal truncation. Journal of Biological Chemistry. 277:2002;11034-11041.
5. Hirohata S., Wang L.W., Miyagi M., Yan L., Seldin M.F., Keene D.R., Crabb J.W., Apte S.S. Punctin, a novel ADAMTS-like molecule (ADAMTSL-1) in extracellular matrix. Journal of Biological Chemistry. 22:2002;22.
6. Hurskainen T.L., Hirohata S., Seldin M.F., Apte S.S. ADAM-TS5, ADAM-TS6, and ADAM-TS7, novel members of a new family of zinc metalloproteases. General features and genomic distribution of the ADAM-TS family. Journal of Biological Chemistry. 274:1999;25555-25563.
7. Kashiwagi M., Tortorella M., Nagase H., Brew K. TIMP-3 is a potent inhibitor of aggrecanase 1 (ADAM-TS4) and aggrecanase 2 (ADAM-TS5). Journal of Biological Chemistry. 276:2001;12501-12504.
8. Kramerova I.A., Kawaguchi N., Fessler L.I., Nelson R.E., Chen Y., Kramerov A.A., Kusche-Gullberg M., Kramer J.M., Ackley B.D., Sieron A.L., Prockop D.J., Fessler J.H. Papilin in development; a pericellular protein with a homology to the ADAMTS metalloproteinases. Development. 127:2000;5475-5485.
9. Kuno K., Kanada N., Nakashima E., Fujiki F., Ichimura F., Matsushima K. Molecular cloning of a gene encoding a new type of metalloproteinase-disintegrin family protein with thrombospondin motifs as an inflammation associated gene. Journal of Biological Chemistry. 272:1997;556-562.
10. Levy G.G., Nichols W.C., Lian E.C., Foroud T., McClintick J.N., McGee B.M., Yang A.Y., Siemieniak D.R., Stark K.R., Gruppo R., Sarode R., Shurin S.B., Chandrasekaran V., Stabler S.P., Sabio H., Bouhassira E.E., Upshaw J.D. Jr., Ginsburg D., Tsai H.M. Mutations in a member of the ADAMTS gene family cause thrombotic thrombocytopenic purpura. Nature. 413:2001;488-494.
11. Luque A., Carpizo D.R., Iruela-Arispe S.M. ADAMTS1/METH1 inhibits endothelial cell proliferation by direct binding and sequestration of VEGF165. Journal of Biological Chemistry. 278:2003;23656-23665.
12. Matthews R.T., Gary S.C., Zerillo C., Pratta M., Solomon K., Arner E.C., Hockfield S. Brain-enriched hyaluronan binding (BEHAB)/brevican cleavage in a glioma cell line is mediated by a disintegrin and metalloproteinase with thrombospondin motifs (ADAMTS) family member. Journal of Biological Chemistry. 275:2000;22695-22703.
13. Nagase H., Kashiwagi M. Aggrecanases and cartilage matrix degradation. Arthritis Research Therapy. 5:2003;94-103.
14. Nusgens B.V., Verellen-Dumoulin C., Hermanns-Le T., De Paepe A., Nuytinck L., Pierard G.E., Lapiere C.M. Evidence for a relationship between Ehlers-Danlos type VII C in humans and bovine dermatosparaxis. Nature Genetics. 1:1992;214-217.
15. Rao C., Foernzler D., Loftus S.K., Liu S., McPherson J.D., Jungers K.A., Apte S.S., Pavan W.J., Beier D.R. A defect in a novel ADAMTS family member is the cause of the belted white-spotting mutation. Development. 130:2003;4665-4672.
16. Sandy J.D., Westling J., Kenagy R.D., Iruela-Arispe M.L., Verscharen C., Rodriguez-Mazaneque J.C., Zimmermann D.R., Lemire J.M., Fischer J.W., Wight T.N., Clowes A.W. Versican V1 proteolysis in human aorta in vivo occurs at the Glu441-Ala442 bond, a site that is cleaved by recombinant ADAMTS-1 and ADAMTS-4a. Journal of Biological Chemistry. 276:2001;13372-13378.
17. Somerville R.P., Longpre J.M., Jungers K.A., Engle J.M., Ross M., Evanko S., Wight T.N., Leduc R., Apte S.S. Characterization of ADAMTS-9 and ADAMTS-20 as a distinct ADAMTS subfamily related to Caenorhabditis elegans GON-1. Journal of Biological Chemistry. 278:2003;9503-9513.
18. Zheng X., Majerus E.M., Sadler J.E. ADAMTS13 and TTP. Current Opinion in Hematology. 9:2002;389-394.