Negatively charged metal oxide nanoparticles interact with the 20S proteasome and differentially modulate its biologic functional effects

ACS Nano

Volumn 7, Issue 9, 2013, Pages 7759-7772

  Falaschetti, Christine A ^a   Paunesku, Tatjana ^a   Kurepa, Jasmina ^b   Nanavati, Dhaval ^c   Chou, Stanley S ^d   De, Mrinmoy ^d   Song, Minha ^e   Jang, Jung Tak ^e   Wu, Aiguo ^f   Dravid, Vinayak P ^d   Cheon, Jinwoo ^e   Smalle, Jan ^b   Woloschak, Gayle E ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

^b UNIVERSITY OF KENTUCKY   (United States)

^c NORTHWESTERN UNIVERSITY   (United States)

^d Northwestern University   (United States)

^e Yonsei University   (South Korea)

^f NINGBO INSTITUTE OF MATERIALS TECHNOLOGY AND ENGINEERING   (China)

Author keywords

iron oxide nanoparticles; proteasome activation; protein adsorption; titanium dioxide nanoparticles; ubiquitin proteasome system

Indexed keywords

IRON OXIDE NANOPARTICLE; PROTEASOMES; PROTEIN ADSORPTION; TITANIUM DIOXIDE NANOPARTICLES; UBIQUITIN-PROTEASOME SYSTEM;

METALLIC COMPOUNDS; NEURODEGENERATIVE DISEASES; PLANTS (BOTANY);

NANOPARTICLES;

ANION; METAL NANOPARTICLE; OXIDE; PROTEASOME;

ARTICLE; BINDING SITE; CHEMISTRY; COMPARATIVE STUDY; ENZYME ACTIVATION; MATERIALS TESTING; PARTICLE SIZE; PROTEIN BINDING; STATIC ELECTRICITY; ULTRASTRUCTURE;

ANIONS; BINDING SITES; ENZYME ACTIVATION; MATERIALS TESTING; METAL NANOPARTICLES; OXIDES; PARTICLE SIZE; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN BINDING; STATIC ELECTRICITY;

EID: 84884961734     PISSN: 19360851     EISSN: 1936086X     Source Type: Journal    
DOI: 10.1021/nn402416h     Document Type: Article

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