Regulation of enzyme activity through interactions with nanoparticles

International Journal of Molecular Sciences

Volumn 10, Issue 10, 2009, Pages 4198-4209

  Wu, Zhaochun ^a   Zhang, Bin ^a   Yan, Bing ^a,b  

^a SHANDONG UNIVERSITY   (China)

^b ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

Author keywords

Enzyme activity; Nanoparticle; Regulation

Indexed keywords

NANOPARTICLE;

BINDING AFFINITY; CONFORMATIONAL TRANSITION; ENZYME ACTIVITY; ENZYME REGULATION; MOLECULAR INTERACTION; PROTEIN BINDING; PROTEIN INTERACTION; REVIEW; SURFACE PROPERTY;

ENZYME ACTIVITY; NANOPARTICLE; REGULATION;

CARBONIC ANHYDRASES; CHYMOTRYPSIN; ENZYME INHIBITORS; ENZYMES; HUMANS; NANOPARTICLES; PARTICLE SIZE; PROTEIN BINDING;

EID: 71649103479     PISSN: None     EISSN: 14220067     Source Type: Journal    
DOI: 10.3390/ijms10104198     Document Type: Review

References (42)

1. Gadek, T.R.; Nicholas, J.B. Small molecule antagonists of proteins. Biochem. Parmacol. 2003, 65, 1-8.
2. Toogood, P.L. Inhibition of protein-protein association by small molecules: Approaches and progress. J. Med. Chem. 2002, 45, 1543-1558.
3. Armbruster, B.N.; Banik, S.S.R.; Guo, C.H.; Smith, A.C.; Counter, C. N-Terminal domains of the human telomerase catalytic subunit required for enzyme activity in vivo. Mol. Cell. Biol. 2001, 21, 7775-7786. (Pubitemid 32988786)
4. Shultz, M.D.; Ham, Y.-W.; Lee, S.-G.; Davis, D.A.; Brown, C.; Chemielewski, J. Small-molecule dimerization inhibitors of wild-type and mutant HIV protease: A focused library approach. J. Am. Chem. Soc. 2004, 126, 9886-9887.
5. Longthorne, V.L.; Williams, G.T. Caspase activity is required for commitment to fas-mediated apoptosis. EMBO J. 1997, 16, 3805-3812. (Pubitemid 27280996)
6. Singh, I. Biochemistry of peroxisomes in health and disease. Mol. Cell. Biochem. 1997, 167, 1-29.
7. D'Armiento, J. Matrix metalloproteinase disruption of the extracellular matrix and cardiac dysfunction. Trends Cardiovasc. Med. 2002, 12, 97-101. (Pubitemid 34462178)
8. Erkizan, H.V.; Kong, Y.L.; Merchant, M.; Schlottmann, S.; Barber-Rotenberg, J.S.; Yuan, L.S.; Abaan, O.D.; Chou, T.-H.; Dakshanamurthy, S.; Brown, M.L.; Ueren, A.; Toretsky, J.A. A small molecule blocking oncogenic protein EWS-FLI1 interaction with RNA helicase A inhibits growth of Ewing's sarcoma. Nature Med. 2009, 15, 750-757.
9. Lo Conte, L.; Chothia, C.; Janin, J. The atomic structure of protein-protein recognition sites. Mol. Bio. 1999, 285, 2177-2198. (Pubitemid 29078179)
10. Porter, A.E.; Gass, M.; Muller, K.; Skepper, J.N.; Midgley, P.A.; Welland, M. Direct imaging of single-walled carbon nanotubes in cells. Nat. Nanotechnol. 2007, 2, 713-717. (Pubitemid 350071068)
11. Mu, Q.X.; Liu, W.; Xing, Y.H.; Zhou, H.Y.; Li, Z.W.; Zhang, Y.; Ji, L.H.; Wang, F.; Si, Z.K.; Zhang, B.; Yan, B. Protein binding by functionalized multiwalled carbon nanotubes is governed by the surface chemistry of both parties and the nanotube diameter. J. Phys. Chem. C 2008, 112, 3300-3307.
12. Peng, X.G.; Manna, L.; Yang, W.D.; Wickham, J.; Scher, E.; Kadavanich, A.; Alivisatos, A.P. Shape control of CdSe nanocrystals. Nature 2000, 404, 59-61.
13. Strano, M.S.; Dyke, C.A.; Usrey, M.L.; Barone, P.W.; Allen, M.J.; Shan, H.W.; Kittrell, C.; Hauge, R.H.; Tour, J.M.; Smalley, R.E. Electronic structure control of single-walled carbon nanotube functionalization. Science 2003, 301, 1519-1522. (Pubitemid 37128540)
14. You, C.C.; Arvizo, R.R.; Rotello, V.M. Regulation of α-chymotrypsin activity on the surface of substrate-functionalized gold nanoparticles. Chem. Comm. 2006, 2905-2907.
15. Erlanger, B.F.; Chen, B.X.; Zhu, M.; Brus, L. Binding of an anti-fullerene IgG monoclonal antibody to single wall carbon nanotubes. Nano Lett. 2001, 1, 465-467. (Pubitemid 33673967)
16. Lin, Y.; Allard, L.F.; Sun, Y.-P. Protein-affinity of single-walled carbon nanotubes in water. J. Phy. Chem. B. 2004, 108, 3760-3764.
17. Stina, L.; Lynch, I.; Eva, T. Systematic investigation of the thermodynamics of HSA adsorption to N-iso-propylacrylamine/N-tert- butylacrylamide copolymer nanoparticles. Effects of particle size and hydrophobicity. Nano Lett. 2007, 7, 914-920.
18. Li, X.J.; Chen, W.; Zhan, Q.W.; Dai, L.M. Direct measurements of interactions between polypeptides and carbon nanotubes. J. Phys. Chem. B 2006, 110, 12621-12625. (Pubitemid 44139450)
19. Irle, S.; Zheng, G.S.; Elstner, M.; Morokuma, K. Formation of fullerene molecules from carbon nanotubes: A quantum chemical molecular dynamics study. Nano Lett. 2003, 3, 465-470. (Pubitemid 37140646)
20. Chen, R.J.; Zhang, Y.G.; Wang, D.W.; Dai, H.J. Noncovalent sidewall functionalization of single-walled carbon nanotubes for protein immobilization. J. Am. Chem. Soc. 2001, 123, 3838-3839.
21. Hong, R.; Emrick, T.; Rotello, V.M. Monolayer-controlled substrate selectivity using noncovalent enzyme-nanoparticle conjugates. J. Am. Chem. Soc. 2004, 126, 13572-13573.
22. You, C.-C.; Arvizo, R.R.; Rotello, V.M. Regulation of α-chymotrypsin activity on the surface of substrate-functionalized gold nanoparticles. Chem. Comm. 2006, 2905-2907.
23. Bradley, K.; Briman, M.; Star, A.; Gruner, G. Charge transfer from adsorbed proteins. Nano Lett. 2004, 4, 253-256.
24. Hostetler, M.J.; Green, S.J.; Stoke, J.J.; Murray, R.W. Monolayers in three dimensions: Synthesis and electrochemistry of ω-functionalized alkanethiolate-stabilized gold clusters compound. J. Am. Chem. Soc. 1996, 118, 4212-4213.
25. Fischer, N.O.; Mclntosh, C.M.; Simard, J.M.; Rotello, V.M. Inhibition of chymotrypsin through surface binding using nanoparticle-based receptors. Proc. Nat. Acad. Sci. USA 2002, 99, 5018-5023.
26. Fischer, N.O.; Verma, A.; Goodman, C.M.; Simard, J.M.; Rotello, V.M. Reversible "irreversible" inhibition of chymotrypsin using nanoparticle receptors. J. Am. Chem. Soc. 2003, 125, 13387-13391.
27. Vertegel, A.A.; Siegel, R.W.; Dordick, J.S. Silica nanoparticle size influences the structure and enzymatic activity of adsorded lysozyme. Langmuir 2004, 20, 6800-6807.
28. Shang, W.; Nuffer, H.H.; Dordick, J.S.; Siegel, R.W. Unfolding of ribonuclease A on silica nanoparticle surfaces. Nano Lett. 2007, 7, 1991-1995.
29. Lundqvist, M.; Sethson, I.; Jonsson, B.H. Protein adsorption onto silica nanoparticles: Conformational changes depend on the particle's curvature and the protein stability. Langmuir 2004, 20, 10639-10647.
30. Asuri, P.; Bale, S.S.; Pangule, R.C.; Shah, D.A.; Kane, R.S.; Dordick, J.S. Structure, function, and stability of enzymes covalently attached to single-walled carbon nanotube. Langmuir 2007, 23, 12318-12321. (Pubitemid 350197408)
31. Karajanagi, S.S.; Vertegel, A.A.; Kane, R.S.; Dordick, J.S. Structure and function of enzymes adsorbed onto single-walled carbon nanotubes. Langmuir 2004, 20, 11594-11599. (Pubitemid 40049633)
32. Lin, Y.; Allard, L.F.; Sun, Y.P. Protein-affinity of single-walled carbon nanotubes in water. J. Phys. Chem. B 2004, 108, 3760-3764.
33. Yi, C.Q.; Fong, C.-C.; Chen, W.W.; Qi, S.J.; Lee, S.-T.; Yang, M.S. Inhibition of biochemical reactions by silica nanowires through modulating enzyme activities. ChemBioChem 2007, 8, 1225-1229.
34. Stiti, M.; Cecchi, A.; Rami, M.; Abdaoui, M.; Barragan-Montero, V.; Scozzafava, A.; Guari, Y.; Winum, J.-Y.; Supuran, C.T. Carbonic anhydrase inhibitor coated gold nanoparticles selectively inhibit the tumor-associated isoform IX over the cytosolic lsozymes I and II. J. Am. Chem. Soc. 2008, 130, 16130-16131.
35. Lu, F.S.; Gu, L.R.; Meziani, M.J.; Wang, X.; Luo, P.J.; Veca, L.M.; Cao, L.; Sun, Y.-P. Advances in bioapplications of carbon nanotubes. Adv. Mater. 2009, 21, 139-152.
36. Tara Elkin, T.; Jiang, X.P.; Taylor, S.; Lin, Y.; Gu, L.R.; Yang, H.; Brown, J.; Collins, S.; Sun, Y.-P. Immuno-carbon nanotubes and recognition of pathogens. ChemBioChem 2005, 6, 640-643.
37. Zhou, H.Y.; Mu, Q.X.; Gao, N.N.; Liu, A.F.; Xing, Y.H.; Gao, S.L.; Zhang, Q.; Qu, G.B.; Chen, Y.Y.; Liu, G.; Zhang, B.; Yan, B. A nano-combinatorial library strategy for the discovery of nanotubes with reduced protein-binding, cytotoxicity, and immune response. Nano Lett. 2008, 8, 859-865.
38. Zhang, B.; Xing, Y.H.; Li, Z.W.; Zhou, H.Y.; Mu, Q.X.; Yan, B. Functionalized carbon nanotubes specifically bind to chymotrypsin catalytic site and regulate its enzymatic function. Nano Lett. 2009, 9, 2280-2284.
39. Hong, R.; Fishcer, N.O.; Verma, A.; Goodman, C.M.; Emrick, T.; Retello, V.M. Control of protein structure and function through surface recognition by tailored nanopartcile scaffolds. J. Am. Chem. Soc. 2004, 126, 739-743.
40. You, C.-C.; De, M.; Rotello, V.M. Contrasting effect of exterior and interior hydrophobic moieties in the complexation of amino acid functionalized gold clusters with α-chymotrypsin. Org. Lett. 2005, 7, 5685-5688.
41. You, C.-C.; De, M.; Han, G.; Rotello, V.M. Tunable inhibition and denaturation of α- chymotrypsin with amino acid-functionalized gold nanoparticles. J. Am. Chem. Soc. 2005, 127, 12873-12881.
42. Bayraktar, H.; Ghosh, P.S.; Rotello, V.M.; Knapp, M.J. Disruption of protein-protein interactions using nanopartciles: Inhibition of cytochrome C peroxidase. Chem. Commun. 2006, 1390-1392.