메뉴 건너뛰기




Volumn 13, Issue 6, 2013, Pages 637-646

Berberine reverts hepatic mitochondrial dysfunction in high-fat fed rats: A possible role for SirT3 activation

Author keywords

Berberine; Liver bioenergetics; Mitochondrial function; Obesity; SirT3

Indexed keywords

ADENOSINE TRIPHOSPHATASE; ADENOSINE TRIPHOSPHATE; BERBERINE; CALCIUM; CYTOCHROME C OXIDASE; OXYGEN; REACTIVE OXYGEN METABOLITE; RNA; SIRTUIN 3; SUCCINATE DEHYDROGENASE;

EID: 84884937949     PISSN: 15677249     EISSN: 18728278     Source Type: Journal    
DOI: 10.1016/j.mito.2013.09.002     Document Type: Article
Times cited : (99)

References (61)
  • 2
    • 0018065969 scopus 로고
    • Mitochondrial cytochrome c: preparation and activity of native and chemically modified cytochromes c
    • Brautigan D.L., Ferguson-Miller S., Margoliash E. Mitochondrial cytochrome c: preparation and activity of native and chemically modified cytochromes c. Meth. Enzymol. 1978, 53:128-164.
    • (1978) Meth. Enzymol. , vol.53 , pp. 128-164
    • Brautigan, D.L.1    Ferguson-Miller, S.2    Margoliash, E.3
  • 3
    • 33744804815 scopus 로고    scopus 로고
    • Inhibition of lipid synthesis through activation of AMP kinase: an additional mechanism for the hypolipidemic effects of berberine
    • Brusq J., Ancellin N., Grondin P., Guillard R., Martin S., Saintillan Y., Issandou M. Inhibition of lipid synthesis through activation of AMP kinase: an additional mechanism for the hypolipidemic effects of berberine. J. Lipid Res. 2006, 47:1281.
    • (2006) J. Lipid Res. , vol.47 , pp. 1281
    • Brusq, J.1    Ancellin, N.2    Grondin, P.3    Guillard, R.4    Martin, S.5    Saintillan, Y.6    Issandou, M.7
  • 4
    • 34047197114 scopus 로고    scopus 로고
    • Regulation of adiponectin and its receptors in response to development of diet-induced obesity in mice
    • Bullen J.W., Bluher S., Kelesidis T., Mantzoros C.S. Regulation of adiponectin and its receptors in response to development of diet-induced obesity in mice. Am. J. Physiol. Endocrinol. Metab. 2007, 292:E1079-E1086.
    • (2007) Am. J. Physiol. Endocrinol. Metab. , vol.292
    • Bullen, J.W.1    Bluher, S.2    Kelesidis, T.3    Mantzoros, C.S.4
  • 6
    • 19444384446 scopus 로고    scopus 로고
    • Fatty acid metabolism is enhanced in type 2 diabetic hearts
    • Carley A.N., Severson D.L. Fatty acid metabolism is enhanced in type 2 diabetic hearts. Biochim. Biophys. Acta 2005, 1734:112-126.
    • (2005) Biochim. Biophys. Acta , vol.1734 , pp. 112-126
    • Carley, A.N.1    Severson, D.L.2
  • 9
    • 79959567900 scopus 로고    scopus 로고
    • Reduced mitochondrial function in obesity-associated fatty liver: SIRT3 takes on the fat
    • Choudhury M., Jonscher K.R., Friedman J.E. Reduced mitochondrial function in obesity-associated fatty liver: SIRT3 takes on the fat. Aging 2011, 3:175-178.
    • (2011) Aging , vol.3 , pp. 175-178
    • Choudhury, M.1    Jonscher, K.R.2    Friedman, J.E.3
  • 10
    • 75349111140 scopus 로고    scopus 로고
    • Regulation of succinate dehydrogenase activity by SIRT3 in mammalian mitochondria
    • Cimen H., Han M.-J., Yang Y., Tong Q., Koc H., Koc E.C. Regulation of succinate dehydrogenase activity by SIRT3 in mammalian mitochondria. Biochemistry 2010, 49:304-311.
    • (2010) Biochemistry , vol.49 , pp. 304-311
    • Cimen, H.1    Han, M.-J.2    Yang, Y.3    Tong, Q.4    Koc, H.5    Koc, E.C.6
  • 11
    • 0038142845 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease
    • Clark J.M., Diehl A.M. Nonalcoholic fatty liver disease. JAMA 2003, 289:3000-3004.
    • (2003) JAMA , vol.289 , pp. 3000-3004
    • Clark, J.M.1    Diehl, A.M.2
  • 12
    • 78650522908 scopus 로고    scopus 로고
    • Hepatoprotective activity of berberine is mediated by inhibition of TNF-α, COX-2, and iNOS expression in CCl(4)-intoxicated mice
    • Domitrović R., Jakovac H., Blagojević G. Hepatoprotective activity of berberine is mediated by inhibition of TNF-α, COX-2, and iNOS expression in CCl(4)-intoxicated mice. Toxicology 2011, 280:33-43.
    • (2011) Toxicology , vol.280 , pp. 33-43
    • Domitrović, R.1    Jakovac, H.2    Blagojević, G.3
  • 13
    • 81055122671 scopus 로고    scopus 로고
    • Sirt5 is a NAD-dependent protein lysine demalonylase and desuccinylase
    • Du J., Zhou Y., Su X., Yu J.J., Khan S., Jiang H., Kim J. Sirt5 is a NAD-dependent protein lysine demalonylase and desuccinylase. Science 2011, 334(6057):806-809.
    • (2011) Science , vol.334 , Issue.6057 , pp. 806-809
    • Du, J.1    Zhou, Y.2    Su, X.3    Yu, J.J.4    Khan, S.5    Jiang, H.6    Kim, J.7
  • 14
    • 77957003282 scopus 로고
    • Mitochondrial respiratory control and the polarographic measurement of ADP:O ratios
    • Estabrook R.W. Mitochondrial respiratory control and the polarographic measurement of ADP:O ratios. Meth. Enzymol. 1967, 10:41-47.
    • (1967) Meth. Enzymol. , vol.10 , pp. 41-47
    • Estabrook, R.W.1
  • 15
    • 84861589885 scopus 로고    scopus 로고
    • Muscle or liver-specific Sirt3 deficiency induces hyperacetylation of mitochondrial proteins without affecting global metabolic homeostasis
    • Fernandez-Marcos P.J., Jeninga E.H., Canto C. Muscle or liver-specific Sirt3 deficiency induces hyperacetylation of mitochondrial proteins without affecting global metabolic homeostasis. Scientific reports 2012.
    • (2012) Scientific reports
    • Fernandez-Marcos, P.J.1    Jeninga, E.H.2    Canto, C.3
  • 18
    • 29744466425 scopus 로고
    • Determination of serum proteins by means of the biuret reaction
    • Gornall A.G., Bardawill C.J., David M.M. Determination of serum proteins by means of the biuret reaction. J. Biol. Chem. 1949, 177:751-766.
    • (1949) J. Biol. Chem. , vol.177 , pp. 751-766
    • Gornall, A.G.1    Bardawill, C.J.2    David, M.M.3
  • 19
    • 0036783050 scopus 로고    scopus 로고
    • The metabolic abnormalities associated with nonalcoholic fatty liver disease
    • Haque M., Sanyal A.J. The metabolic abnormalities associated with nonalcoholic fatty liver disease. Best Pract. Res. Clin. Gastroenterol. 2002, 16:709-731.
    • (2002) Best Pract. Res. Clin. Gastroenterol. , vol.16 , pp. 709-731
    • Haque, M.1    Sanyal, A.J.2
  • 24
    • 0018665167 scopus 로고
    • Membrane potential of mitochondria measured with an electrode sensitive to tetraphenyl phosphonium and relationship between proton electrochemical potential and phosphorylation potential in steady state
    • Kamo N., Muratsugu M., Hongoh R., Kobatake Y. Membrane potential of mitochondria measured with an electrode sensitive to tetraphenyl phosphonium and relationship between proton electrochemical potential and phosphorylation potential in steady state. J. Membr. Biol. 1979, 49:105-121.
    • (1979) J. Membr. Biol. , vol.49 , pp. 105-121
    • Kamo, N.1    Muratsugu, M.2    Hongoh, R.3    Kobatake, Y.4
  • 25
    • 0036788293 scopus 로고    scopus 로고
    • Dysfunction of mitochondria in human skeletal muscle in type 2 diabetes
    • Kelley D.E., He J., Menshikova E.V., Ritov V.B. Dysfunction of mitochondria in human skeletal muscle in type 2 diabetes. Diabetes 2002, 51:2944-2950.
    • (2002) Diabetes , vol.51 , pp. 2944-2950
    • Kelley, D.E.1    He, J.2    Menshikova, E.V.3    Ritov, V.B.4
  • 29
    • 77955347446 scopus 로고    scopus 로고
    • Sirtuin 3, a new target of PGC-1α, plays an important role in the suppression of ROS and mitochondrial biogenesis
    • Kong X., Wang R., Xue Y., Liu X., Zhang H., Chen Y., Fang F., Chang Y. Sirtuin 3, a new target of PGC-1α, plays an important role in the suppression of ROS and mitochondrial biogenesis. PLoS One 2010, 5:e11707.
    • (2010) PLoS One , vol.5
    • Kong, X.1    Wang, R.2    Xue, Y.3    Liu, X.4    Zhang, H.5    Chen, Y.6    Fang, F.7    Chang, Y.8
  • 31
    • 33749336146 scopus 로고    scopus 로고
    • Berberine, a natural plant product, activates AMP-activated protein kinase with beneficial metabolic effects in diabetic and insulin resistant states
    • Lee Y., Kim W., Kim K., Yoon M., Cho H., Shen Y., Ye J., Lee C., Oh W., Kim C. Berberine, a natural plant product, activates AMP-activated protein kinase with beneficial metabolic effects in diabetic and insulin resistant states. Diabetes 2006, 55:2256.
    • (2006) Diabetes , vol.55 , pp. 2256
    • Lee, Y.1    Kim, W.2    Kim, K.3    Yoon, M.4    Cho, H.5    Shen, Y.6    Ye, J.7    Lee, C.8    Oh, W.9    Kim, C.10
  • 32
    • 1842708890 scopus 로고    scopus 로고
    • Therapeutic effects of berberine in impaired glucose tolerance rats and its influence on insulin secretion
    • Leng S.H., Lu F.E., Xu L.J. Therapeutic effects of berberine in impaired glucose tolerance rats and its influence on insulin secretion. Acta Pharmacol. Sin. 2004, 25:496-502.
    • (2004) Acta Pharmacol. Sin. , vol.25 , pp. 496-502
    • Leng, S.H.1    Lu, F.E.2    Xu, L.J.3
  • 33
    • 0014968250 scopus 로고
    • Carbohydrate homeostasis
    • Levine R., Haft D.E. Carbohydrate homeostasis. N. Engl. J. Med. 1970, 283:237-246.
    • (1970) N. Engl. J. Med. , vol.283 , pp. 237-246
    • Levine, R.1    Haft, D.E.2
  • 34
    • 78649385842 scopus 로고    scopus 로고
    • Beneficial effect of berberine on hepatic insulin resistance in diabetic hamsters possibly involves in SREBPs, LXRα and PPARα transcriptional programs
    • Liu X., Li G., Zhu H., Huang L., Liu Y., Ma C., Qin C. Beneficial effect of berberine on hepatic insulin resistance in diabetic hamsters possibly involves in SREBPs, LXRα and PPARα transcriptional programs. Endocr. J. 2010, 57:881-893.
    • (2010) Endocr. J. , vol.57 , pp. 881-893
    • Liu, X.1    Li, G.2    Zhu, H.3    Huang, L.4    Liu, Y.5    Ma, C.6    Qin, C.7
  • 35
    • 67449164807 scopus 로고    scopus 로고
    • Berberine promotes glucagon-like peptide-1 (7-36) amide secretion in streptozotocin-induced diabetic rats
    • Lu S.-S., Yu Y.-L., Zhu H.-J., Liu X.-D., Liu L., Liu Y.-W., Wang P., Xie L., Wang G.-J. Berberine promotes glucagon-like peptide-1 (7-36) amide secretion in streptozotocin-induced diabetic rats. J. Endocrinol. 2009, 200:159-165.
    • (2009) J. Endocrinol. , vol.200 , pp. 159-165
    • Lu, S.-S.1    Yu, Y.-L.2    Zhu, H.-J.3    Liu, X.-D.4    Liu, L.5    Liu, Y.-W.6    Wang, P.7    Xie, L.8    Wang, G.-J.9
  • 36
    • 0030932708 scopus 로고    scopus 로고
    • Benzoquinone inhibits the voltage-dependent induction of the mitochondrial permeability transition caused by redox-cycling naphthoquinones
    • Palmeira C.M., Wallace K.B. Benzoquinone inhibits the voltage-dependent induction of the mitochondrial permeability transition caused by redox-cycling naphthoquinones. Toxicol. Appl. Pharmacol. 1997, 143:338-347.
    • (1997) Toxicol. Appl. Pharmacol. , vol.143 , pp. 338-347
    • Palmeira, C.M.1    Wallace, K.B.2
  • 37
    • 0028146853 scopus 로고
    • Interactions of herbicides 2, 4-D and dinoseb with liver mitochondrial bioenergetics
    • Palmeira C.M., Moreno A.J., Madeira V. Interactions of herbicides 2, 4-D and dinoseb with liver mitochondrial bioenergetics. Toxicol. Appl. Pharmacol. 1994, 127:50-57.
    • (1994) Toxicol. Appl. Pharmacol. , vol.127 , pp. 50-57
    • Palmeira, C.M.1    Moreno, A.J.2    Madeira, V.3
  • 38
    • 4744350801 scopus 로고    scopus 로고
    • A comparative study of plant and animal mitochondria exposed to paraquat reveals that hydrogen peroxide is not related to the observed toxicity
    • Peixoto F., Vicente J., Madeira V. A comparative study of plant and animal mitochondria exposed to paraquat reveals that hydrogen peroxide is not related to the observed toxicity. Toxicol. In Vitro 2004, 18:733-739.
    • (2004) Toxicol. In Vitro , vol.18 , pp. 733-739
    • Peixoto, F.1    Vicente, J.2    Madeira, V.3
  • 39
    • 34249792393 scopus 로고    scopus 로고
    • Role of mitochondria in non-alcoholic fatty liver disease
    • Pessayre D. Role of mitochondria in non-alcoholic fatty liver disease. J. Gastroenterol. Hepatol. 2007, 22(Suppl. 1):S20-S27.
    • (2007) J. Gastroenterol. Hepatol. , vol.22 , Issue.SUPPL. 1
    • Pessayre, D.1
  • 41
    • 0033852206 scopus 로고    scopus 로고
    • Bile acids affect liver mitochondrial bioenergetics: possible relevance for cholestasis therapy
    • Rolo A.P., Oliveira P.J., Moreno A.J., Palmeira C.M. Bile acids affect liver mitochondrial bioenergetics: possible relevance for cholestasis therapy. Toxicol. Sci. 2000, 57:177-185.
    • (2000) Toxicol. Sci. , vol.57 , pp. 177-185
    • Rolo, A.P.1    Oliveira, P.J.2    Moreno, A.J.3    Palmeira, C.M.4
  • 42
    • 0037223317 scopus 로고    scopus 로고
    • Elevated free fatty acids impair glucose metabolism in women: decreased stimulation of muscle glucose uptake and suppression of splanchnic glucose production during combined hyperinsulinemia and hyperglycemia
    • Shah P., Vella A., Basu A., Basu R., Adkins A., Schwenk W.F., Johnson C.M., Nair K.S., Jensen M.D., Rizza R.A. Elevated free fatty acids impair glucose metabolism in women: decreased stimulation of muscle glucose uptake and suppression of splanchnic glucose production during combined hyperinsulinemia and hyperglycemia. Diabetes 2003, 52:38-42.
    • (2003) Diabetes , vol.52 , pp. 38-42
    • Shah, P.1    Vella, A.2    Basu, A.3    Basu, R.4    Adkins, A.5    Schwenk, W.F.6    Johnson, C.M.7    Nair, K.S.8    Jensen, M.D.9    Rizza, R.A.10
  • 43
    • 0016378057 scopus 로고
    • Determination of the activity of succinate, NADH, choline, and alpha-glycerophosphate dehydrogenases
    • Singer T.P. Determination of the activity of succinate, NADH, choline, and alpha-glycerophosphate dehydrogenases. Methods Biochem. Anal. 1974, 22:123-175.
    • (1974) Methods Biochem. Anal. , vol.22 , pp. 123-175
    • Singer, T.P.1
  • 45
    • 33645241135 scopus 로고    scopus 로고
    • Decreased ANT content in Zucker fatty rats: relevance for altered hepatic mitochondrial bioenergetics in steatosis
    • Teodoro J., Rolo A.P., Oliveira P.J., Palmeira C.M. Decreased ANT content in Zucker fatty rats: relevance for altered hepatic mitochondrial bioenergetics in steatosis. FEBS Lett. 2006, 580:2153-2157.
    • (2006) FEBS Lett. , vol.580 , pp. 2153-2157
    • Teodoro, J.1    Rolo, A.P.2    Oliveira, P.J.3    Palmeira, C.M.4
  • 46
    • 54949089576 scopus 로고    scopus 로고
    • Differential alterations in mitochondrial function induced by a choline-deficient diet: understanding fatty liver disease progression
    • Teodoro J.S., Rolo A.P., Duarte F.V., Simões A.M., Palmeira C.M. Differential alterations in mitochondrial function induced by a choline-deficient diet: understanding fatty liver disease progression. Mitochondrion 2008, 8:367-376.
    • (2008) Mitochondrion , vol.8 , pp. 367-376
    • Teodoro, J.S.1    Rolo, A.P.2    Duarte, F.V.3    Simões, A.M.4    Palmeira, C.M.5
  • 47
    • 84884942995 scopus 로고    scopus 로고
    • The Global Burden | International Diabetes Federation URL (last accessed 5.20.2013))
    • The Global Burden | International Diabetes Federation [WWW Document].idf.org (URL http://www.idf.org/diabetesatlas/5e/regional-overviews (last accessed 5.20.2013)).
    • [WWW Document].idf.org
  • 49
    • 70349157209 scopus 로고    scopus 로고
    • Ameliorative effect of berberine on endothelial dysfunction in diabetic rats induced by high-fat diet and streptozotocin
    • Wang C., Li J., Lv X., Zhang M., Song Y., Chen L., Liu Y. Ameliorative effect of berberine on endothelial dysfunction in diabetic rats induced by high-fat diet and streptozotocin. Eur. J. Pharmacol. 2009, 620:131-137.
    • (2009) Eur. J. Pharmacol. , vol.620 , pp. 131-137
    • Wang, C.1    Li, J.2    Lv, X.3    Zhang, M.4    Song, Y.5    Chen, L.6    Liu, Y.7
  • 50
    • 66249092436 scopus 로고    scopus 로고
    • Berberine prevents hyperglycemia-induced endothelial injury and enhances vasodilatation via adenosine monophosphate-activated protein kinase and endothelial nitric oxide synthase
    • Wang Y., Huang Y., Lam K.S., Li Y., Wong W.T., Ye H., Lau C.W., Vanhoutte P.M., Xu A. Berberine prevents hyperglycemia-induced endothelial injury and enhances vasodilatation via adenosine monophosphate-activated protein kinase and endothelial nitric oxide synthase. Cardiovasc. Res. 2009, 82:484-492.
    • (2009) Cardiovasc. Res. , vol.82 , pp. 484-492
    • Wang, Y.1    Huang, Y.2    Lam, K.S.3    Li, Y.4    Wong, W.T.5    Ye, H.6    Lau, C.W.7    Vanhoutte, P.M.8    Xu, A.9
  • 51
    • 78751647742 scopus 로고    scopus 로고
    • Hypoglycemic and insulin-sensitizing effects of berberine in high-fat diet-and streptozotocin-induced diabetic rats
    • Wang Y., Campbell T., Perry B. Hypoglycemic and insulin-sensitizing effects of berberine in high-fat diet-and streptozotocin-induced diabetic rats. Metabolism 2011, 60:298-305.
    • (2011) Metabolism , vol.60 , pp. 298-305
    • Wang, Y.1    Campbell, T.2    Perry, B.3
  • 52
    • 79751496044 scopus 로고    scopus 로고
    • Berberine improves glucose metabolism in diabetic rats by inhibition of hepatic gluconeogenesis
    • Xia X., Yan J., Shen Y., Tang K., Yin J., Zhang Y., Yang D., Liang H., Ye J., Weng J. Berberine improves glucose metabolism in diabetic rats by inhibition of hepatic gluconeogenesis. PLoS One 2011, 6:e16556.
    • (2011) PLoS One , vol.6
    • Xia, X.1    Yan, J.2    Shen, Y.3    Tang, K.4    Yin, J.5    Zhang, Y.6    Yang, D.7    Liang, H.8    Ye, J.9    Weng, J.10
  • 56
    • 79952362196 scopus 로고    scopus 로고
    • Protective effect of berberine on antioxidant enzymes and positive transcription elongation factor b expression in diabetic rat liver
    • Zhou J.Y., Zhou S.-W. Protective effect of berberine on antioxidant enzymes and positive transcription elongation factor b expression in diabetic rat liver. Fitoterapia 2011, 82:184-189.
    • (2011) Fitoterapia , vol.82 , pp. 184-189
    • Zhou, J.Y.1    Zhou, S.-W.2
  • 57
    • 0035912594 scopus 로고    scopus 로고
    • Doxorubicin-induced persistent oxidative stress to cardiac myocytes
    • Zhou S., Palmeira C., Wallace K. Doxorubicin-induced persistent oxidative stress to cardiac myocytes. Toxicol. Lett. 2001, 121:151-157.
    • (2001) Toxicol. Lett. , vol.121 , pp. 151-157
    • Zhou, S.1    Palmeira, C.2    Wallace, K.3
  • 59
    • 50449090523 scopus 로고    scopus 로고
    • Berberine acutely inhibits insulin secretion from beta-cells through 3',5-cyclic adenosine 5'-monophosphate signaling pathway
    • Zhou L., Wang X., Shao L., Yang Y., Shang W., Yuan G., Jiang B., Li F., Tang J., Jing H., Chen M. Berberine acutely inhibits insulin secretion from beta-cells through 3',5-cyclic adenosine 5'-monophosphate signaling pathway. Endocrinology 2008, 149:4510-4518.
    • (2008) Endocrinology , vol.149 , pp. 4510-4518
    • Zhou, L.1    Wang, X.2    Shao, L.3    Yang, Y.4    Shang, W.5    Yuan, G.6    Jiang, B.7    Li, F.8    Tang, J.9    Jing, H.10    Chen, M.11
  • 60
    • 60949108484 scopus 로고    scopus 로고
    • Protective effect of berberine on beta cells in streptozotocin- and high-carbohydrate/high-fat diet-induced diabetic rats
    • Zhou J., Zhou S., Tang J., Zhang K., Guang L., Huang Y., Xu Y., Ying Y., Zhang L., Li D. Protective effect of berberine on beta cells in streptozotocin- and high-carbohydrate/high-fat diet-induced diabetic rats. Eur. J. Pharmacol. 2009, 606:262-268.
    • (2009) Eur. J. Pharmacol. , vol.606 , pp. 262-268
    • Zhou, J.1    Zhou, S.2    Tang, J.3    Zhang, K.4    Guang, L.5    Huang, Y.6    Xu, Y.7    Ying, Y.8    Zhang, L.9    Li, D.10


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.