Metabolic syndrome induces inflammation and impairs gonadotropin-releasing hormone neurons in the preoptic area of the hypothalamus in rabbits

Molecular and Cellular Endocrinology

Volumn 382, Issue 1, 2014, Pages 107-119

  Morelli, Annamaria ^a   Sarchielli, Erica ^a   Comeglio, Paolo ^a   Filippi, Sandra ^a   Vignozzi, Linda ^a   Marini, Mirca ^a   Rastrelli, Giulia ^a   Maneschi, Elena ^a   Cellai, Ilaria ^a   Persani, Luca ^b,d   Adorini, Luciano ^c   Vannelli, Gabriella B ^a   Maggi, Mario ^a,d,e  

^a UNIVERSITY OF FLORENCE   (Italy)

^b UNIVERSITY OF MILAN   (Italy)

^c INTERCEPT PHARMACEUTICALS   (United States)

^d CIRMAR   (Italy)

^e NATIONAL INSTITUTE OF BIOSTRUCTURES AND BIOSYSTEMS   (Italy)

Author keywords

Glucose intolerance; GLUT4; Hypogonadotropic hypogonadism; Hypothalamic inflammation; IL 6; Metabolic syndrome

Indexed keywords

CYCLOOXYGENASE 2 INHIBITOR; FARNESOID X RECEPTOR; GLUCOSE TRANSPORTER 4; GONADORELIN; INFLIXIMAB; INTERLEUKIN 6; METASTIN; OBETICHOLIC ACID; TUMOR NECROSIS FACTOR ALPHA ANTIBODY;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; GENE EXPRESSION; GLUCOSE INTOLERANCE; GLUCOSE METABOLISM; HYPOGONADOTROPIC HYPOGONADISM; HYPOTHALAMUS; HYPOTHALAMUS DISEASE; INFLAMMATION; LIPID DIET; MALE; METABOLIC SYNDROME X; MICROGLIA; NERVE CELL STIMULATION; NONHUMAN; PREOPTIC AREA; PRIORITY JOURNAL; PROTEIN EXPRESSION; RABBIT;

GLUCOSE INTOLERANCE; GLUT4; HYPOGONADOTROPIC HYPOGONADISM; HYPOTHALAMIC INFLAMMATION; IL-6; METABOLIC SYNDROME;

ANIMALS; ANTIBODIES, MONOCLONAL; BIOLOGICAL MARKERS; CHENODEOXYCHOLIC ACID; DIET, HIGH-FAT; GENE EXPRESSION REGULATION; GLUCOSE TRANSPORTER TYPE 4; GONADOTROPIN-RELEASING HORMONE; IMMUNOHISTOCHEMISTRY; INFLAMMATION; MALE; METABOLIC SYNDROME X; NEURONS; PREOPTIC AREA; RABBITS; RECEPTORS, G-PROTEIN-COUPLED; RNA, MESSENGER;

EID: 84884931921     PISSN: 03037207     EISSN: 18728057     Source Type: Journal    
DOI: 10.1016/j.mce.2013.09.017     Document Type: Article

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