Testosterone and farnesoid X receptor agonist INT-747 counteract high fat diet-induced bladder alterations in a rabbit model of metabolic syndrome

Journal of Steroid Biochemistry and Molecular Biology

Volumn 132, Issue 1-2, 2012, Pages 80-92

  Morelli, Annamaria ^a   Comeglio, Paolo ^a   Filippi, Sandra ^a   Sarchielli, Erica ^a   Cellai, Ilaria ^a   Vignozzi, Linda ^a   Yehiely Cohen, Ravit ^a   Maneschi, Elena ^a   Gacci, Mauro ^a   Carini, Marco ^a   Adorini, Luciano ^b   Vannelli, Gabriella B ^a   Maggi, Mario ^a  

^a UNIVERSITY OF FLORENCE   (Italy)

^b INTERCEPT PHARMACEUTICALS   (United States)

Author keywords

Bladder steroid receptors; FXR agonist; Metabolic syndrome related hypogonadism; Metabolic syndrome related LUTS; RhoA ROCK signaling

Indexed keywords

4 (1 AMINOETHYL) N (4 PYRIDYL)CYCLOHEXANECARBOXAMIDE; CARBACHOL; OBETICHOLIC ACID; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; TESTOSTERONE;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLADDER DISEASE; BLADDER FIBROSIS; BLADDER FUNCTION; BLADDER HYPOXIA; CELL INFILTRATION; CONTROLLED STUDY; DRUG EFFECT; FIBROSIS; GLUCOSE INTOLERANCE; HYPOXIA; IN VITRO STUDY; INTRAABDOMINAL FAT; LIPID DIET; MALE; METABOLIC SYNDROME X; NONHUMAN; SMOOTH MUSCLE;

ANDROGENS; ANIMALS; BLOOD GLUCOSE; CELL MOVEMENT; CHENODEOXYCHOLIC ACID; CHOLESTEROL; DIET, HIGH-FAT; DISEASE MODELS, ANIMAL; HYPOGONADISM; MALE; METABOLIC SYNDROME X; MUSCLE CONTRACTION; MYOCYTES, SMOOTH MUSCLE; PROSTATE; RABBITS; RECEPTORS, ANDROGEN; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RNA, MESSENGER; TESTOSTERONE; TRIGLYCERIDES; TRIPTORELIN PAMOATE; URINARY BLADDER;

ORYCTOLAGUS CUNICULUS;

EID: 84864310696     PISSN: 09600760     EISSN: 18791220     Source Type: Journal    
DOI: 10.1016/j.jsbmb.2012.02.007     Document Type: Article

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