메뉴 건너뛰기




Volumn 4, Issue 4, 2013, Pages 499-521

Genes involved in type 1 diabetes: An update

Author keywords

Genome wide association studies (GWAS); Immune system; Natural killer (NK) cells; Pancreatic cells; Susceptibility loci; Type 1 diabetes (T1D)

Indexed keywords

ADAPTIVE IMMUNITY; ADCY3 GENE; C2ORF79 GENE; CENPO GENE; CLEC16A GENE; CUX2 GENE; DIABETOGENESIS; DLL1 GENE; DNAJC27 GENE; DNMT3A GENE; EFR3B GENE; FAM120B GENE; GENE; GENE IDENTIFICATION; GENE LOCUS; GENETIC ANALYSIS; GENETIC ASSOCIATION; GENETIC PREDISPOSITION; HTR1A GENE; HUMAN; INNATE IMMUNITY; INSULIN DEPENDENT DIABETES MELLITUS; LMO7 GENE; NCOA1 GENE; NONHUMAN; PDCD2 GENE; PHF10 GENE; POMC GENE; PSMB1 GENE; REVIEW; SINGLE NUCLEOTIDE POLYMORPHISM; TBP GENE; TCTE3 GENE; ADENYLATE CYCLASE 3 GENE; CENTROMERE PROTEIN O GENE; CHROMOSOME 12Q; CHROMOSOME 13Q; CHROMOSOME 2Q; CHROMOSOME 5P; CHROMOSOME 6Q; CHROMOSOME STRUCTURE; GENETIC SUSCEPTIBILITY; IMMUNE SYSTEM; MOLECULAR PATHOLOGY; PROOPIOMELANOCORTIN GENE;

EID: 84884889492     PISSN: None     EISSN: 20734425     Source Type: Journal    
DOI: 10.3390/genes4030499     Document Type: Review
Times cited : (65)

References (116)
  • 1
    • 65549158358 scopus 로고    scopus 로고
    • Conference on "multidisciplinary approaches to nutritional problems". Symposium on "diabetes and health". Nutrition interventions for the prevention of type 2 diabetes
    • Steyn, N.P.; Lambert, E.V.; Tabana, H. Conference on "multidisciplinary approaches to nutritional problems". Symposium on "diabetes and health". Nutrition interventions for the prevention of type 2 diabetes. Proc. Nutr. Soc.2009, 68, 55-70.
    • (2009) Proc. Nutr. Soc , vol.68 , pp. 55-70
    • Steyn, N.P.1    Lambert, E.V.2    Tabana, H.3
  • 2
    • 84884897469 scopus 로고    scopus 로고
    • International Diabetes Federation. Available online, accessed on 11 July 2013
    • International Diabetes Federation. Available online: http://www.idf.org/diabetesatlas/ (accessed on 11 July 2013).
  • 3
    • 0034635768 scopus 로고    scopus 로고
    • Variation and trends in incidence of childhood diabetes in europe
    • Eurodiab ACE study group
    • Eurodiab ACE study group. Variation and trends in incidence of childhood diabetes in europe. Lancet 2000, 355, 873-876.
    • (2000) Lancet , vol.355 , pp. 873-876
  • 4
    • 0033429304 scopus 로고    scopus 로고
    • Worldwide increase in incidence of type I{cyrillic, ukrainian} diabetes-The analysis of the data on published incidence trends
    • Onkamo, P.; Vaananen, S.; Karvonen, M.; Tuomilehto, J. Worldwide increase in incidence of type I{cyrillic, ukrainian} diabetes-The analysis of the data on published incidence trends. Diabetologia 1999, 42, 1395-1403.
    • (1999) Diabetologia , vol.42 , pp. 1395-1403
    • Onkamo, P.1    Vaananen, S.2    Karvonen, M.3    Tuomilehto, J.4
  • 5
    • 0035076548 scopus 로고    scopus 로고
    • Heterogeneity of type I diabetes: Analysis of monozygotic twins in great britain and the united states
    • Redondo, M.J.; Yu, L.; Hawa, M.; Mackenzie, T.; Pyke, D.A.; Eisenbarth, G.S.; Leslie, R.D. Heterogeneity of type I diabetes: Analysis of monozygotic twins in great britain and the united states. Diabetologia 2001, 44, 354-362.
    • (2001) Diabetologia , vol.44 , pp. 354-362
    • Redondo, M.J.1    Yu, L.2    Hawa, M.3    Mackenzie, T.4    Pyke, D.A.5    Eisenbarth, G.S.6    Leslie, R.D.7
  • 6
    • 68249108329 scopus 로고    scopus 로고
    • Prediction and interaction in complex disease genetics: Experience in type 1 diabetes
    • Clayton, D.G. Prediction and interaction in complex disease genetics: Experience in type 1 diabetes. PLoS Genet. 2009, 5, e1000540.
    • (2009) PLoS Genet , vol.5
    • Clayton, D.G.1
  • 7
    • 0025094344 scopus 로고
    • Mapping genes in diabetes. Genetic epidemiological perspective
    • Rich, S.S. Mapping genes in diabetes. Genetic epidemiological perspective. Diabetes 1990, 39, 1315-1319.
    • (1990) Diabetes , vol.39 , pp. 1315-1319
    • Rich, S.S.1
  • 8
    • 0016746677 scopus 로고
    • Evidence for hl-a-linked genes in "juvenile" diabetes mellitus
    • Cudworth, A.G.; Woodrow, J.C. Evidence for hl-a-linked genes in "juvenile" diabetes mellitus. Br. Med. J. 1975, 3, 133-135.
    • (1975) Br. Med. J , vol.3 , pp. 133-135
    • Cudworth, A.G.1    Woodrow, J.C.2
  • 10
    • 0015883122 scopus 로고
    • Histocompatibility (hl-a) antigens, lymphocytotoxic antibodies and tissue antibodies in patients with diabetes mellitus
    • Singal, D.P.; Blajchman, M.A. Histocompatibility (hl-a) antigens, lymphocytotoxic antibodies and tissue antibodies in patients with diabetes mellitus. Diabetes 1973, 22, 429-432.
    • (1973) Diabetes , vol.22 , pp. 429-432
    • Singal, D.P.1    Blajchman, M.A.2
  • 11
    • 0021343570 scopus 로고
    • A polymorphic locus near the human insulin gene is associated with insulin-dependent diabetes mellitus
    • Bell, G.I.; Horita, S.; Karam, J.H. A polymorphic locus near the human insulin gene is associated with insulin-dependent diabetes mellitus. Diabetes 1984, 33, 176-183.
    • (1984) Diabetes , vol.33 , pp. 176-183
    • Bell, G.I.1    Horita, S.2    Karam, J.H.3
  • 15
    • 33745240931 scopus 로고    scopus 로고
    • A genome-wide association study of nonsynonymous snps identifies a type 1 diabetes locus in the interferon-induced helicase (ifih1) region
    • Smyth, D.J.; Cooper, J.D.; Bailey, R.; Field, S.; Burren, O.; Smink, L.J.; Guja, C.; Ionescu-Tirgoviste, C.; Widmer, B.; Dunger, D.B. et al. A genome-wide association study of nonsynonymous snps identifies a type 1 diabetes locus in the interferon-induced helicase (ifih1) region. Nat. Genet. 2006, 38, 617-619.
    • (2006) Nat. Genet , vol.38 , pp. 617-619
    • Smyth, D.J.1    Cooper, J.D.2    Bailey, R.3    Field, S.4    Burren, O.5    Smink, L.J.6    Guja, C.7    Ionescu-Tirgoviste, C.8    Widmer, B.9    Dunger, D.B.10
  • 16
    • 79959503826 scopus 로고    scopus 로고
    • The international hapmap project
    • International HapMap Consortium
    • International HapMap Consortium. The international hapmap project. Nature 2003, 426, 789-796.
    • (2003) Nature , vol.426 , pp. 789-796
  • 17
    • 79959524146 scopus 로고    scopus 로고
    • A haplotype map of the human genome
    • International HapMap Consortium
    • International HapMap Consortium. A haplotype map of the human genome. Nature 2005, 437, 1299-1320.
    • (2005) Nature , vol.437 , pp. 1299-1320
  • 19
    • 84969213492 scopus 로고    scopus 로고
    • Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls
    • Wellcome Trust Case Control Consortium
    • Wellcome Trust Case Control Consortium. Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature 2007, 447, 661-678.
    • (2007) Nature , vol.447 , pp. 661-678
  • 23
    • 45549099440 scopus 로고    scopus 로고
    • Multidomain sts/tula proteins are novel cellular regulators
    • Tsygankov, A.Y. Multidomain sts/tula proteins are novel cellular regulators. IUBMB Life 2008, 60, 224-231.
    • (2008) IUBMB Life , vol.60 , pp. 224-231
    • Tsygankov, A.Y.1
  • 24
    • 0033559313 scopus 로고    scopus 로고
    • Cloning and characterization of a lymphoid-specific, inducible human protein tyrosine phosphatase, lyp
    • Cohen, S.; Dadi, H.; Shaoul, E.; Sharfe, N.; Roifman, C.M. Cloning and characterization of a lymphoid-specific, inducible human protein tyrosine phosphatase, lyp. Blood 1999, 93, 2013-2024.
    • (1999) Blood , vol.93 , pp. 2013-2024
    • Cohen, S.1    Dadi, H.2    Shaoul, E.3    Sharfe, N.4    Roifman, C.M.5
  • 25
    • 75649103221 scopus 로고    scopus 로고
    • Follow-up of 1715 snps from the wellcome trust case control consortium genome-wide association study in type I{cyrillic, ukrainian} diabetes families
    • Cooper, J.D.; Walker, N.M.; Smyth, D.J.; Downes, K.; Healy, B.C.; Todd, J.A. Follow-up of 1715 snps from the wellcome trust case control consortium genome-wide association study in type I{cyrillic, ukrainian} diabetes families. Genes Immun. 2009, 10, S85-S94.
    • (2009) Genes Immun , vol.10
    • Cooper, J.D.1    Walker, N.M.2    Smyth, D.J.3    Downes, K.4    Healy, B.C.5    Todd, J.A.6
  • 26
    • 84870063293 scopus 로고    scopus 로고
    • Rs11203203 is associated with type 1 diabetes risk in population pre-screened for high-risk hla-dr,dq genotypes
    • Johnson, K.; Wong, R.; Barriga, K.J.; Klingensmith, G.; Ziegler, A.G.; Rewers, M.J.; Steck, A.K. Rs11203203 is associated with type 1 diabetes risk in population pre-screened for high-risk hla-dr,dq genotypes. Pediatr. Diabetes 2012, 13, 611-615.
    • (2012) Pediatr. Diabetes , vol.13 , pp. 611-615
    • Johnson, K.1    Wong, R.2    Barriga, K.J.3    Klingensmith, G.4    Ziegler, A.G.5    Rewers, M.J.6    Steck, A.K.7
  • 28
    • 33745827044 scopus 로고    scopus 로고
    • Genetics of kidneys in diabetes (gokind) study: A genetics collection available for identifying genetic susceptibility factors for diabetic nephropathy in type 1 diabetes
    • Mueller, P.W.; Rogus, J.J.; Cleary, P.A.; Zhao, Y.; Smiles, A.M.; Steffes, M.W.; Bucksa, J.; Gibson, T.B.; Cordovado, S.K.; Krolewski, A.S. et al. Genetics of kidneys in diabetes (gokind) study: A genetics collection available for identifying genetic susceptibility factors for diabetic nephropathy in type 1 diabetes. J. Am. Soc. Nephrol. JASN 2006, 17, 1782-1790.
    • (2006) J. Am. Soc. Nephrol. JASN , vol.17 , pp. 1782-1790
    • Mueller, P.W.1    Rogus, J.J.2    Cleary, P.A.3    Zhao, Y.4    Smiles, A.M.5    Steffes, M.W.6    Bucksa, J.7    Gibson, T.B.8    Cordovado, S.K.9    Krolewski, A.S.10
  • 32
    • 75649122271 scopus 로고    scopus 로고
    • Analysis of 55 autoimmune disease and type ii diabetes loci: Further confirmation of chromosomes 4q27, 12q13.2 and 12q24.13 as type i diabetes loci, and support for a new locus, 12q13.3-q14.1
    • Cooper, J.D.; Walker, N.M.; Healy, B.C.; Smyth, D.J.; Downes, K.; Todd, J.A. Analysis of 55 autoimmune disease and type ii diabetes loci: Further confirmation of chromosomes 4q27, 12q13.2 and 12q24.13 as type i diabetes loci, and support for a new locus, 12q13.3-q14.1. Genes Immun. 2009, 10, S95-S120.
    • (2009) Genes Immun , vol.10
    • Cooper, J.D.1    Walker, N.M.2    Healy, B.C.3    Smyth, D.J.4    Downes, K.5    Todd, J.A.6
  • 33
    • 61849117976 scopus 로고    scopus 로고
    • Analysis of 17 autoimmune disease-associated variants in type 1 diabetes identifies 6q23/tnfaip3 as a susceptibility locus
    • Fung, E.Y.; Smyth, D.J.; Howson, J.M.; Cooper, J.D.; Walker, N.M.; Stevens, H.; Wicker, L.S.; Todd, J.A. Analysis of 17 autoimmune disease-associated variants in type 1 diabetes identifies 6q23/tnfaip3 as a susceptibility locus. Genes Immun. 2009, 10, 188-191.
    • (2009) Genes Immun , vol.10 , pp. 188-191
    • Fung, E.Y.1    Smyth, D.J.2    Howson, J.M.3    Cooper, J.D.4    Walker, N.M.5    Stevens, H.6    Wicker, L.S.7    Todd, J.A.8
  • 40
    • 59149093799 scopus 로고    scopus 로고
    • Variation within the clec16a gene shows consistent disease association with both multiple sclerosis and type 1 diabetes in sardinia
    • Zoledziewska, M.; Costa, G.; Pitzalis, M.; Cocco, E.; Melis, C.; Moi, L.; Zavattari, P.; Murru, R.; Lampis, R.; Morelli, L. et al. Variation within the clec16a gene shows consistent disease association with both multiple sclerosis and type 1 diabetes in sardinia. Genes Immun. 2009, 10, 15-17.
    • (2009) Genes Immun , vol.10 , pp. 15-17
    • Zoledziewska, M.1    Costa, G.2    Pitzalis, M.3    Cocco, E.4    Melis, C.5    Moi, L.6    Zavattari, P.7    Murru, R.8    Lampis, R.9    Morelli, L.10
  • 41
    • 66949120294 scopus 로고    scopus 로고
    • Intron polymorphism in the kiaa0350 gene is reproducibly associated with susceptibility to type 1 diabetes (t1d) in the han chinese population
    • Wu, X.; Zhu, X.; Wang, X.; Ma, J.; Zhu, S.; Li, J.; Liu, Y. Intron polymorphism in the kiaa0350 gene is reproducibly associated with susceptibility to type 1 diabetes (t1d) in the han chinese population. Clin. Endocrinol. 2009, 71, 46-49.
    • (2009) Clin. Endocrinol , vol.71 , pp. 46-49
    • Wu, X.1    Zhu, X.2    Wang, X.3    Ma, J.4    Zhu, S.5    Li, J.6    Liu, Y.7
  • 42
    • 73349115848 scopus 로고    scopus 로고
    • The imprinted dlk1-meg3 gene region on chromosome 14q32.2 alters susceptibility to type 1 diabetes
    • Wallace, C.; Smyth, D.J.; Maisuria-Armer, M.; Walker, N.M.; Todd, J.A.; Clayton, D.G. The imprinted dlk1-meg3 gene region on chromosome 14q32.2 alters susceptibility to type 1 diabetes. Nat. Genet. 2010, 42, 68-71.
    • (2010) Nat. Genet , vol.42 , pp. 68-71
    • Wallace, C.1    Smyth, D.J.2    Maisuria-Armer, M.3    Walker, N.M.4    Todd, J.A.5    Clayton, D.G.6
  • 46
    • 84863724842 scopus 로고    scopus 로고
    • 1,000 genomes-based imputation identifies novel and refined associations for the wellcome trust case control consortium phase 1 data
    • Huang, J.; Ellinghaus, D.; Franke, A.; Howie, B.; Li, Y. 1,000 genomes-based imputation identifies novel and refined associations for the wellcome trust case control consortium phase 1 data. Eur. J. Hum. Genet.2012, 20, 801-805.
    • (2012) Eur. J. Hum. Genet , vol.20 , pp. 801-805
    • Huang, J.1    Ellinghaus, D.2    Franke, A.3    Howie, B.4    Li, Y.5
  • 47
    • 27744492083 scopus 로고    scopus 로고
    • Reconstructing immune phylogeny: New perspectives
    • Litman, G.W.; Cannon, J.P.; Dishaw, L.J. Reconstructing immune phylogeny: New perspectives. Nat. Rev. Immunol. 2005, 5, 866-879.
    • (2005) Nat. Rev. Immunol , vol.5 , pp. 866-879
    • Litman, G.W.1    Cannon, J.P.2    Dishaw, L.J.3
  • 48
    • 84884590165 scopus 로고    scopus 로고
    • Candidate genes expressed in human islets and their role in the pathogenesis of type 1 diabetes
    • in press
    • Storling, J.; Brorsson, C.A. Candidate genes expressed in human islets and their role in the pathogenesis of type 1 diabetes. Curr. Diab. Rep. 2013, in press.
    • (2013) Curr. Diab. Rep
    • Storling, J.1    Brorsson, C.A.2
  • 49
    • 78751662679 scopus 로고    scopus 로고
    • Type 1 diabetes: Etiology, immunology, and therapeutic strategies
    • Van Belle, T.L.; Coppieters, K.T.; von Herrath, M.G. Type 1 diabetes: Etiology, immunology, and therapeutic strategies. Physiol. Rev. 2011, 91, 79-118.
    • (2011) Physiol. Rev , vol.91 , pp. 79-118
    • van Belle, T.L.1    Coppieters, K.T.2    von Herrath, M.G.3
  • 50
    • 84872728861 scopus 로고    scopus 로고
    • Immunological pathways to β-cell damage in type 1 diabetes
    • Peakman, M. Immunological pathways to β-cell damage in type 1 diabetes. Diabet. Med. 2013, 30, 147-154.
    • (2013) Diabet. Med , vol.30 , pp. 147-154
    • Peakman, M.1
  • 53
    • 0141533076 scopus 로고    scopus 로고
    • Dual function of c-type lectin-like receptors in the immune system
    • Cambi, A.; Figdor, C.G. Dual function of c-type lectin-like receptors in the immune system. Curr. Opin. Cell Biol. 2003, 15, 539-546.
    • (2003) Curr. Opin. Cell Biol , vol.15 , pp. 539-546
    • Cambi, A.1    Figdor, C.G.2
  • 55
    • 84863655786 scopus 로고    scopus 로고
    • The correlation between the clec16a gene and genetic susceptibility to type 1 diabetes in chinese children
    • 2012, Article ID 245384
    • Sang, Y.; Zong, W.; Yan, J.; Liu, M. The correlation between the clec16a gene and genetic susceptibility to type 1 diabetes in chinese children. Int. J. Endocrinol. 2012, 2012, Article ID 245384.
    • (2012) Int. J. Endocrinol
    • Sang, Y.1    Zong, W.2    Yan, J.3    Liu, M.4
  • 59
    • 80051706384 scopus 로고    scopus 로고
    • Interrogating the complex role of chromosome 16p13.13 in multiple sclerosis susceptibility: Independent genetic signals in the ciita-clec16a-socs1 gene complex
    • Zuvich, R.L.; Bush, W.S.; McCauley, J.L.; Beecham, A.H.; de Jager, P.L.; Ivinson, A.J.; Compston, A.; Hafler, D.A.; Hauser, S.L.; Sawcer, S.J. et al. Interrogating the complex role of chromosome 16p13.13 in multiple sclerosis susceptibility: Independent genetic signals in the ciita-clec16a-socs1 gene complex. Hum. Mol. Genet. 2011, 20, 3517-3524.
    • (2011) Hum. Mol. Genet , vol.20 , pp. 3517-3524
    • Zuvich, R.L.1    Bush, W.S.2    McCauley, J.L.3    Beecham, A.H.4    de Jager, P.L.5    Ivinson, A.J.6    Compston, A.7    Hafler, D.A.8    Hauser, S.L.9    Sawcer, S.J.10
  • 61
    • 70350650472 scopus 로고    scopus 로고
    • A large-scale replication study identifies tnip1, prdm1, jazf1, uhrf1bp1 and il10 as risk loci for systemic lupus erythematosus
    • Gateva, V.; Sandling, J.K.; Hom, G.; Taylor, K.E.; Chung, S.A.; Sun, X.; Ortmann, W.; Kosoy, R.; Ferreira, R.C.; Nordmark, G. et al. A large-scale replication study identifies tnip1, prdm1, jazf1, uhrf1bp1 and il10 as risk loci for systemic lupus erythematosus. Nat. Genet. 2009, 41, 1228-1233.
    • (2009) Nat. Genet , vol.41 , pp. 1228-1233
    • Gateva, V.1    Sandling, J.K.2    Hom, G.3    Taylor, K.E.4    Chung, S.A.5    Sun, X.6    Ortmann, W.7    Kosoy, R.8    Ferreira, R.C.9    Nordmark, G.10
  • 62
    • 78751689465 scopus 로고    scopus 로고
    • Polymorphisms at 16p13 are associated with systemic lupus erythematosus in the chinese population
    • Zhang, Z.; Cheng, Y.; Zhou, X.; Li, Y.; Gao, J.; Han, J.; Quan, C.; He, S.; Lv, Y.; Hu, D. et al. Polymorphisms at 16p13 are associated with systemic lupus erythematosus in the chinese population. J. Med. Genet. 2011, 48, 69-72.
    • (2011) J. Med. Genet , vol.48 , pp. 69-72
    • Zhang, Z.1    Cheng, Y.2    Zhou, X.3    Li, Y.4    Gao, J.5    Han, J.6    Quan, C.7    He, S.8    Lv, Y.9    Hu, D.10
  • 65
  • 66
    • 77955463306 scopus 로고    scopus 로고
    • A clec16a variant confers risk for juvenile idiopathic arthritis and anti-cyclic citrullinated peptide antibody negative rheumatoid arthritis
    • Skinningsrud, B.; Lie, B.A.; Husebye, E.S.; Kvien, T.K.; Forre, O.; Flato, B.; Stormyr, A.; Joner, G.; Njolstad, P.R.; Egeland, T. et al. A clec16a variant confers risk for juvenile idiopathic arthritis and anti-cyclic citrullinated peptide antibody negative rheumatoid arthritis. Ann. Rheum. Dis. 2010, 69, 1471-1474.
    • (2010) Ann. Rheum. Dis , vol.69 , pp. 1471-1474
    • Skinningsrud, B.1    Lie, B.A.2    Husebye, E.S.3    Kvien, T.K.4    Forre, O.5    Flato, B.6    Stormyr, A.7    Joner, G.8    Njolstad, P.R.9    Egeland, T.10
  • 70
    • 77949361027 scopus 로고    scopus 로고
    • The novel endosomal membrane protein ema interacts with the class c vps-hops complex to promote endosomal maturation
    • Kim, S.; Wairkar, Y.P.; Daniels, R.W.; DiAntonio, A. The novel endosomal membrane protein ema interacts with the class c vps-hops complex to promote endosomal maturation. J. Cell Biol. 2010, 188, 717-734.
    • (2010) J. Cell Biol , vol.188 , pp. 717-734
    • Kim, S.1    Wairkar, Y.P.2    Daniels, R.W.3    Diantonio, A.4
  • 71
    • 84860811842 scopus 로고    scopus 로고
    • Drosophila golgi membrane protein ema promotes autophagosomal growth and function
    • Kim, S.; Naylor, S.A.; DiAntonio, A. Drosophila golgi membrane protein ema promotes autophagosomal growth and function. Proc. Natl. Acad. Sci. USA 2012, 109, E1072-E1081.
    • (2012) Proc. Natl. Acad. Sci. USA , vol.109
    • Kim, S.1    Naylor, S.A.2    Diantonio, A.3
  • 73
    • 3242743242 scopus 로고    scopus 로고
    • Involvement of lmo7 in the association of two cell-cell adhesion molecules, nectin and e-cadherin, through afadin and alpha-actinin in epithelial cells
    • Ooshio, T.; Irie, K.; Morimoto, K.; Fukuhara, A.; Imai, T.; Takai, Y. Involvement of lmo7 in the association of two cell-cell adhesion molecules, nectin and e-cadherin, through afadin and alpha-actinin in epithelial cells. J. Biol. Chem.2004, 279, 31365-31373.
    • (2004) J. Biol. Chem , vol.279 , pp. 31365-31373
    • Ooshio, T.1    Irie, K.2    Morimoto, K.3    Fukuhara, A.4    Imai, T.5    Takai, Y.6
  • 74
    • 4444253507 scopus 로고    scopus 로고
    • Requirement of the actin cytoskeleton for the association of nectins with other cell adhesion molecules at adherens and tight junctions in mdck cells
    • Yamada, A.; Irie, K.; Fukuhara, A.; Ooshio, T.; Takai, Y. Requirement of the actin cytoskeleton for the association of nectins with other cell adhesion molecules at adherens and tight junctions in mdck cells. Genes Cells 2004, 9, 843-855.
    • (2004) Genes Cells , vol.9 , pp. 843-855
    • Yamada, A.1    Irie, K.2    Fukuhara, A.3    Ooshio, T.4    Takai, Y.5
  • 75
    • 0036875910 scopus 로고    scopus 로고
    • A novel gene containing pdz and lim domains, pcd1, is overexpressed in human colorectal cancer
    • Furuya, M.; Tsuji, N.; Endoh, T.; Moriai, R.; Kobayashi, D.; Yagihashi, A.; Watanabe, N. A novel gene containing pdz and lim domains, pcd1, is overexpressed in human colorectal cancer. Anticancer Res. 2002, 22, 4183-4186.
    • (2002) Anticancer Res , vol.22 , pp. 4183-4186
    • Furuya, M.1    Tsuji, N.2    Endoh, T.3    Moriai, R.4    Kobayashi, D.5    Yagihashi, A.6    Watanabe, N.7
  • 76
    • 0034665547 scopus 로고    scopus 로고
    • Pcd1, a novel gene containing pdz and lim domains, is overexpressed in several human cancers
    • Kang, S.; Xu, H.; Duan, X.; Liu, J.J.; He, Z.; Yu, F.; Zhou, S.; Meng, X.Q.; Cao, M.; Kennedy, G.C. Pcd1, a novel gene containing pdz and lim domains, is overexpressed in several human cancers. Cancer Res. 2000, 60, 5296-5302.
    • (2000) Cancer Res , vol.60 , pp. 5296-5302
    • Kang, S.1    Xu, H.2    Duan, X.3    Liu, J.J.4    He, Z.5    Yu, F.6    Zhou, S.7    Meng, X.Q.8    Cao, M.9    Kennedy, G.C.10
  • 77
    • 26944450881 scopus 로고    scopus 로고
    • Differential expression and molecular characterisation of lmo7, myo1e, sash1, and mcoln2 genes in btk-defective b-cells
    • Lindvall, J.M.; Blomberg, K.E.; Wennborg, A.; Smith, C.I. Differential expression and molecular characterisation of lmo7, myo1e, sash1, and mcoln2 genes in btk-defective b-cells. Cell. Immunol. 2005, 235, 46-55.
    • (2005) Cell. Immunol , vol.235 , pp. 46-55
    • Lindvall, J.M.1    Blomberg, K.E.2    Wennborg, A.3    Smith, C.I.4
  • 78
    • 0038683341 scopus 로고    scopus 로고
    • An engineered 800 kilobase deletion of uchl3 and lmo7 on mouse chromosome 14 causes defects in viability, postnatal growth and degeneration of muscle and retina
    • Semenova, E.; Wang, X.; Jablonski, M.M.; Levorse, J.; Tilghman, S.M. An engineered 800 kilobase deletion of uchl3 and lmo7 on mouse chromosome 14 causes defects in viability, postnatal growth and degeneration of muscle and retina. Hum. Mol. Genet. 2003, 12, 1301-1312.
    • (2003) Hum. Mol. Genet , vol.12 , pp. 1301-1312
    • Semenova, E.1    Wang, X.2    Jablonski, M.M.3    Levorse, J.4    Tilghman, S.M.5
  • 83
    • 0034933420 scopus 로고    scopus 로고
    • An atp-binding cassette gene (abcg5) from the abcg (white) gene subfamily maps to human chromosome 2p21 in the region of the sitosterolemia locus
    • Shulenin, S.; Schriml, L.M.; Remaley, A.T.; Fojo, S.; Brewer, B.; Allikmets, R.; Dean, M. An atp-binding cassette gene (abcg5) from the abcg (white) gene subfamily maps to human chromosome 2p21 in the region of the sitosterolemia locus. Cytogenet. Cell Genet. 2001, 92, 204-208.
    • (2001) Cytogenet. Cell Genet , vol.92 , pp. 204-208
    • Shulenin, S.1    Schriml, L.M.2    Remaley, A.T.3    Fojo, S.4    Brewer, B.5    Allikmets, R.6    Dean, M.7
  • 84
    • 0034221041 scopus 로고    scopus 로고
    • Alstrom syndrome: Confirmation of linkage to chromosome 2p12-13 and phenotypic heterogeneity in three affected sibs
    • Zumsteg, U.; Muller, P.Y.; Miserez, A.R. Alstrom syndrome: Confirmation of linkage to chromosome 2p12-13 and phenotypic heterogeneity in three affected sibs. J. Med. Genet. 2000, 37, E8.
    • (2000) J. Med. Genet , vol.37
    • Zumsteg, U.1    Muller, P.Y.2    Miserez, A.R.3
  • 85
    • 0028846193 scopus 로고
    • Sequence and characterization of a coactivator for the steroid hormone receptor superfamily
    • Onate, S.A.; Tsai, S.Y.; Tsai, M.J.; O'Malley, B.W. Sequence and characterization of a coactivator for the steroid hormone receptor superfamily. Science 1995, 270, 1354-1357.
    • (1995) Science , vol.270 , pp. 1354-1357
    • Onate, S.A.1    Tsai, S.Y.2    Tsai, M.J.3    O'Malley, B.W.4
  • 86
    • 0030912539 scopus 로고    scopus 로고
    • The transcriptional co-activator p/cip binds cbp and mediates nuclear-receptor function
    • Torchia, J.; Rose, D.W.; Inostroza, J.; Kamei, Y.; Westin, S.; Glass, C.K.; Rosenfeld, M.G. The transcriptional co-activator p/cip binds cbp and mediates nuclear-receptor function. Nature 1997, 387, 677-684.
    • (1997) Nature , vol.387 , pp. 677-684
    • Torchia, J.1    Rose, D.W.2    Inostroza, J.3    Kamei, Y.4    Westin, S.5    Glass, C.K.6    Rosenfeld, M.G.7
  • 87
  • 88
    • 0036972975 scopus 로고    scopus 로고
    • Characterization of the human adenylyl cyclase gene family: Cdna, gene structure, and tissue distribution of the nine isoforms
    • Ludwig, M.G.; Seuwen, K. Characterization of the human adenylyl cyclase gene family: Cdna, gene structure, and tissue distribution of the nine isoforms. J. Recept. Signal Transduct. Res. 2002, 22, 79-110.
    • (2002) J. Recept. Signal Transduct. Res , vol.22 , pp. 79-110
    • Ludwig, M.G.1    Seuwen, K.2
  • 89
    • 0033681491 scopus 로고    scopus 로고
    • Disruption of the type iii adenylyl cyclase gene leads to peripheral and behavioral anosmia in transgenic mice
    • Wong, S.T.; Trinh, K.; Hacker, B.; Chan, G.C.; Lowe, G.; Gaggar, A.; Xia, Z.; Gold, G.H.; Storm, D.R. Disruption of the type iii adenylyl cyclase gene leads to peripheral and behavioral anosmia in transgenic mice. Neuron 2000, 27, 487-497.
    • (2000) Neuron , vol.27 , pp. 487-497
    • Wong, S.T.1    Trinh, K.2    Hacker, B.3    Chan, G.C.4    Lowe, G.5    Gaggar, A.6    Xia, Z.7    Gold, G.H.8    Storm, D.R.9
  • 91
    • 84863282535 scopus 로고    scopus 로고
    • A case of early-onset obesity, hypocortisolism, and skin pigmentation problem due to a novel homozygous mutation in the proopiomelanocortin (pomc) gene in an indian boy
    • Hung, C.N.; Poon, W.T.; Lee, C.Y.; Law, C.Y.; Chan, A.Y. A case of early-onset obesity, hypocortisolism, and skin pigmentation problem due to a novel homozygous mutation in the proopiomelanocortin (pomc) gene in an indian boy. J. Pediatr. Endocrinol. Metab. 2012, 25, 175-179.
    • (2012) J. Pediatr. Endocrinol. Metab , vol.25 , pp. 175-179
    • Hung, C.N.1    Poon, W.T.2    Lee, C.Y.3    Law, C.Y.4    Chan, A.Y.5
  • 92
    • 0031838353 scopus 로고    scopus 로고
    • Severe early-onset obesity, adrenal insufficiency and red hair pigmentation caused by pomc mutations in humans
    • Krude, H.; Biebermann, H.; Luck, W.; Horn, R.; Brabant, G.; Gruters, A. Severe early-onset obesity, adrenal insufficiency and red hair pigmentation caused by pomc mutations in humans. Nat. Genet. 1998, 19, 155-157.
    • (1998) Nat. Genet , vol.19 , pp. 155-157
    • Krude, H.1    Biebermann, H.2    Luck, W.3    Horn, R.4    Brabant, G.5    Gruters, A.6
  • 93
    • 80053131467 scopus 로고    scopus 로고
    • Association analysis of proopiomelanocortin (pomc) haplotypes in type 1 diabetes in a uk population
    • Martin, R.J.; Savage, D.A.; Carson, D.J.; McKnight, A.J.; Maxwell, A.P.; Patterson, C.C. Association analysis of proopiomelanocortin (pomc) haplotypes in type 1 diabetes in a uk population. Diabetes Metab. 2011, 37, 298-304.
    • (2011) Diabetes Metab , vol.37 , pp. 298-304
    • Martin, R.J.1    Savage, D.A.2    Carson, D.J.3    McKnight, A.J.4    Maxwell, A.P.5    Patterson, C.C.6
  • 94
    • 0037184258 scopus 로고    scopus 로고
    • The human DNA methyltransferases dnmt3a and dnmt3b have two types of promoters with different cpg contents
    • Yanagisawa, Y.; Ito, E.; Yuasa, Y.; Maruyama, K. The human DNA methyltransferases dnmt3a and dnmt3b have two types of promoters with different cpg contents. Biochim. Biophys. Acta 2002, 1577, 457-465.
    • (2002) Biochim. Biophys. Acta , vol.1577 , pp. 457-465
    • Yanagisawa, Y.1    Ito, E.2    Yuasa, Y.3    Maruyama, K.4
  • 95
    • 67949083572 scopus 로고    scopus 로고
    • Microrna-mediated switching of chromatin-remodelling complexes in neural development
    • Yoo, A.S.; Staahl, B.T.; Chen, L.; Crabtree, G.R. Microrna-mediated switching of chromatin-remodelling complexes in neural development. Nature 2009, 460, 642-646.
    • (2009) Nature , vol.460 , pp. 642-646
    • Yoo, A.S.1    Staahl, B.T.2    Chen, L.3    Crabtree, G.R.4
  • 96
    • 33644759259 scopus 로고    scopus 로고
    • Delta-like1-induced notch1 signaling regulates the human plasmacytoid dendritic cell versus t-cell lineage decision through control of gata-3 and spi-b
    • Dontje, W.; Schotte, R.; Cupedo, T.; Nagasawa, M.; Scheeren, F.; Gimeno, R.; Spits, H.; Blom, B. Delta-like1-induced notch1 signaling regulates the human plasmacytoid dendritic cell versus t-cell lineage decision through control of gata-3 and spi-b. Blood 2006, 107, 2446-2452.
    • (2006) Blood , vol.107 , pp. 2446-2452
    • Dontje, W.1    Schotte, R.2    Cupedo, T.3    Nagasawa, M.4    Scheeren, F.5    Gimeno, R.6    Spits, H.7    Blom, B.8
  • 99
    • 34948898984 scopus 로고    scopus 로고
    • Constitutive coactivator of peroxisome proliferator-activated receptor (ppargamma), a novel coactivator of ppargamma that promotes adipogenesis
    • Li, D.; Kang, Q.; Wang, D.M. Constitutive coactivator of peroxisome proliferator-activated receptor (ppargamma), a novel coactivator of ppargamma that promotes adipogenesis. Mol. Endocrinol. 2007, 21, 2320-2333.
    • (2007) Mol. Endocrinol , vol.21 , pp. 2320-2333
    • Li, D.1    Kang, Q.2    Wang, D.M.3
  • 100
    • 0031571609 scopus 로고    scopus 로고
    • Linkage of tata-binding protein and proteasome subunit c5 genes in mice and humans reveals synteny conserved between mammals and invertebrates
    • Trachtulec, Z.; Hamvas, R.M.; Forejt, J.; Lehrach, H.R.; Vincek, V.; Klein, J. Linkage of tata-binding protein and proteasome subunit c5 genes in mice and humans reveals synteny conserved between mammals and invertebrates. Genomics 1997, 44, 1-7.
    • (1997) Genomics , vol.44 , pp. 1-7
    • Trachtulec, Z.1    Hamvas, R.M.2    Forejt, J.3    Lehrach, H.R.4    Vincek, V.5    Klein, J.6
  • 103
    • 0024616142 scopus 로고
    • The product of a fos-related gene, fra-1, binds cooperatively to the ap-1 site with jun: Transcription factor ap-1 is comprised of multiple protein complexes
    • Cohen, D.R.; Ferreira, P.C.; Gentz, R.; Franza, B.R., Jr.; Curran, T. The product of a fos-related gene, fra-1, binds cooperatively to the ap-1 site with jun: Transcription factor ap-1 is comprised of multiple protein complexes. Genes Dev. 1989, 3, 173-184.
    • (1989) Genes Dev , vol.3 , pp. 173-184
    • Cohen, D.R.1    Ferreira, P.C.2    Gentz, R.3    Franza Jr., B.R.4    Curran, T.5
  • 104
    • 12344281173 scopus 로고    scopus 로고
    • Biochemical characterization of the mammalian cux2 protein
    • Gingras, H.; Cases, O.; Krasilnikova, M.; Berube, G.; Nepveu, A. Biochemical characterization of the mammalian cux2 protein. Gene 2005, 344, 273-285.
    • (2005) Gene , vol.344 , pp. 273-285
    • Gingras, H.1    Cases, O.2    Krasilnikova, M.3    Berube, G.4    Nepveu, A.5
  • 105
    • 40949107902 scopus 로고    scopus 로고
    • Cux2 (cutl2) integrates neural progenitor development with cell-cycle progression during spinal cord neurogenesis
    • Iulianella, A.; Sharma, M.; Durnin, M.; Vanden Heuvel, G.B.; Trainor, P.A. Cux2 (cutl2) integrates neural progenitor development with cell-cycle progression during spinal cord neurogenesis. Development 2008, 135, 729-741.
    • (2008) Development , vol.135 , pp. 729-741
    • Iulianella, A.1    Sharma, M.2    Durnin, M.3    Vanden, H.G.B.4    Trainor, P.A.5
  • 107
    • 12944249216 scopus 로고    scopus 로고
    • Ala45thr polymorphism of the neurod1 gene and diabetes susceptibility: A meta-analysis
    • Kavvoura, F.K.; Ioannidis, J.P. Ala45thr polymorphism of the neurod1 gene and diabetes susceptibility: A meta-analysis. Hum. Genet. 2005, 116, 192-199.
    • (2005) Hum. Genet , vol.116 , pp. 192-199
    • Kavvoura, F.K.1    Ioannidis, J.P.2
  • 108
    • 0035212224 scopus 로고    scopus 로고
    • A genomewide scan for type 1-diabetes susceptibility in scandinavian families: Identification of new loci with evidence of interactions
    • Nerup, J.; Pociot, F. A genomewide scan for type 1-diabetes susceptibility in scandinavian families: Identification of new loci with evidence of interactions. Am. J. Hum. Genet. 2001, 69, 1301-1313.
    • (2001) Am. J. Hum. Genet , vol.69 , pp. 1301-1313
    • Nerup, J.1    Pociot, F.2
  • 109
    • 0032970989 scopus 로고    scopus 로고
    • A review of central 5-ht receptors and their function
    • Barnes, N.M.; Sharp, T. A review of central 5-ht receptors and their function. Neuropharmacology 1999, 38, 1083-1152.
    • (1999) Neuropharmacology , vol.38 , pp. 1083-1152
    • Barnes, N.M.1    Sharp, T.2
  • 110
    • 43249113900 scopus 로고    scopus 로고
    • Role of serotonin in the hepato-gastrointestinal tract: An old molecule for new perspectives
    • Lesurtel, M.; Soll, C.; Graf, R.; Clavien, P.A. Role of serotonin in the hepato-gastrointestinal tract: An old molecule for new perspectives. Cell. Mol. life Sci. 2008, 65, 940-952.
    • (2008) Cell. Mol. Life Sci , vol.65 , pp. 940-952
    • Lesurtel, M.1    Soll, C.2    Graf, R.3    Clavien, P.A.4
  • 111
  • 112
    • 2442622503 scopus 로고    scopus 로고
    • Effects of prior 5-hydroxytryptamine exposure on rat islet insulin secretory and phospholipase c responses
    • Zawalich, W.S.; Tesz, G.J.; Zawalich, K.C. Effects of prior 5-hydroxytryptamine exposure on rat islet insulin secretory and phospholipase c responses. Endocrine 2004, 23, 11-16.
    • (2004) Endocrine , vol.23 , pp. 11-16
    • Zawalich, W.S.1    Tesz, G.J.2    Zawalich, K.C.3
  • 113
    • 0031911161 scopus 로고    scopus 로고
    • 5-hydroxytryptamine-1 receptor activation inhibits endocrine pancreatic secretion in humans
    • Coulie, B.; Tack, J.; Bouillon, R.; Peeters, T.; Janssens, J. 5-hydroxytryptamine-1 receptor activation inhibits endocrine pancreatic secretion in humans. Am. J. Physiol. 1998, 274, E317-E320.
    • (1998) Am. J. Physiol , vol.274
    • Coulie, B.1    Tack, J.2    Bouillon, R.3    Peeters, T.4    Janssens, J.5
  • 114
    • 32944464820 scopus 로고    scopus 로고
    • Hypothalamic 5-ht functional regulation through 5-ht1a and 5-ht2c receptors during pancreatic regeneration
    • Mohanan, V.V.; Khan, R.; Paulose, C.S. Hypothalamic 5-ht functional regulation through 5-ht1a and 5-ht2c receptors during pancreatic regeneration. Life Sci. 2006, 78, 1603-1609.
    • (2006) Life Sci , vol.78 , pp. 1603-1609
    • Mohanan, V.V.1    Khan, R.2    Paulose, C.S.3
  • 115
    • 0027326833 scopus 로고
    • Expression of 5ht1a receptors on activated human t cells. Regulation of cyclic amp levels and t cell proliferation by 5-hydroxytryptamine
    • Aune, T.M.; McGrath, K.M.; Sarr, T.; Bombara, M.P.; Kelley, K.A. Expression of 5ht1a receptors on activated human t cells. Regulation of cyclic amp levels and t cell proliferation by 5-hydroxytryptamine. J. Immunol. 1993, 151, 1175-1183.
    • (1993) J. Immunol , vol.151 , pp. 1175-1183
    • Aune, T.M.1    McGrath, K.M.2    Sarr, T.3    Bombara, M.P.4    Kelley, K.A.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.