From disease association to risk assessment: An optimistic view from genome-wide association studies on type 1 diabetes

PLoS Genetics

Volumn 5, Issue 10, 2009, Pages

  Wei, Zhi ^a   Wang, Kai ^b   Qu, Hui Qi ^c   Zhang, Haitao ^b   Bradfield, Jonathan ^b   Kim, Cecilia ^b   Frackleton, Edward ^b   Hou, Cuiping ^b   Glessner, Joseph T ^b   Chiavacci, Rosetta ^b   Stanley, Charles ^b   Monos, Dimitri ^b   Grant, Struan F A ^b   Polychronakos, Constantin ^c   Hakonarson, Hakon ^b  

^a University Heights   (United States)

^b CHILDREN S HOSPITAL OF PHILADELPHIA   (United States)

^c MCGILL UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

AREA UNDER THE CURVE; ARTICLE; CONTROL GROUP; CONTROLLED STUDY; DISEASE ASSOCIATION; DISEASE MARKER; GENE INTERACTION; GENE LOCUS; GENETIC ASSOCIATION; GENETIC SUSCEPTIBILITY; GENOTYPE; HUMAN; INSULIN DEPENDENT DIABETES MELLITUS; LOGISTIC REGRESSION ANALYSIS; MACHINE LEARNING; RECEIVER OPERATING CHARACTERISTIC; RISK ASSESSMENT; SENSITIVITY AND SPECIFICITY; SINGLE NUCLEOTIDE POLYMORPHISM; SUPPORT VECTOR MACHINE; ALGORITHM; ARTIFICIAL INTELLIGENCE; BIOLOGICAL MODEL; DNA MICROARRAY; GENETIC DATABASE; GENETIC MARKER; GENETIC PREDISPOSITION; GENETICS; METHODOLOGY; REPRODUCIBILITY;

ALGORITHMS; AREA UNDER CURVE; ARTIFICIAL INTELLIGENCE; DATABASES, GENETIC; DIABETES MELLITUS, TYPE 1; GENETIC MARKERS; GENETIC PREDISPOSITION TO DISEASE; GENOME-WIDE ASSOCIATION STUDY; HUMANS; MODELS, GENETIC; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; POLYMORPHISM, SINGLE NUCLEOTIDE; REPRODUCIBILITY OF RESULTS; RISK ASSESSMENT; ROC CURVE;

EID: 73449129712     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1000678     Document Type: Article

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