Pseudomonas putida AlkA and AlkB Proteins Comprise Different Defense Systems for the Repair of Alkylation Damage to DNA - In Vivo, In Vitro, and In Silico Studies

PLoS ONE

Volumn 8, Issue 10, 2013, Pages

  Mielecki, Damian ^a   Saumaa, Signe ^b   Wrzesiński, Michał ^a   Maciejewska, Agnieszka M ^a   Zuchniewicz, Karolina ^a   Sikora, Anna ^a   Piwowarski, Jan ^a   Nieminuszczy, Jadwiga ^a   Kivisaar, Maia ^b   Grzesiuk, Elzbieta ^a  

^a INSTITUTE OF BIOCHEMISTRY AND BIOPHYSICS   (Poland)

^b UNIVERSITY OF TARTU   (Estonia)

Author keywords

[No Author keywords available]

Indexed keywords

ADA PROTEIN; ALKA GLYCOSYLASE; ALKB DIOXYGENASE; BACTERIAL DNA; BACTERIAL PROTEIN; MESYLIC ACID METHYL ESTER; METHYLNITRONITROSOGUANIDINE; UNCLASSIFIED DRUG;

ADA GENE; ADAPTIVE IMMUNITY; ALKA GENE; ALKB GENE; ALKYLATION; ARTICLE; BACTERIAL CELL; BACTERIAL GENE; BACTERIAL IMMUNITY; BACTERIAL STRAIN; BACTERIAL SURVIVAL; CELL PROTECTION; COMPUTER MODEL; CONTROLLED STUDY; CYTOTOXICITY; DNA DAMAGE; DNA REPAIR; ENZYME SPECIFICITY; ENZYME SUBSTRATE; ESCHERICHIA COLI; GENE EXPRESSION REGULATION; GENE FUNCTION; GENE MUTATION; GENETIC CONSERVATION; IN VITRO STUDY; IN VIVO STUDY; MUTAGENESIS; NONHUMAN; NUCLEOTIDE SEQUENCE; PROMOTER REGION; PROTEIN FUNCTION; PSEUDOMONAS PUTIDA; REGULON; STRAIN DIFFERENCE; TOXICITY TESTING; UPREGULATION;

ALKYLATING AGENTS; ALKYLATION; AMINO ACID SEQUENCE; BACTERIAL PROTEINS; CLUSTER ANALYSIS; CONSENSUS SEQUENCE; DNA DAMAGE; DNA GLYCOSYLASES; DNA REPAIR; ESCHERICHIA COLI; GENOME, BACTERIAL; MOLECULAR SEQUENCE DATA; MUTAGENESIS; NUCLEOTIDE MOTIFS; PROMOTER REGIONS, GENETIC; PSEUDOMONAS PUTIDA; SEQUENCE ALIGNMENT; SUBSTRATE SPECIFICITY;

EID: 84884850908     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0076198     Document Type: Article

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