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Volumn 9, Issue 7, 2013, Pages

Cytotoxic T Cells Mediate Pathology and Metastasis in Cutaneous Leishmaniasis

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; GRANZYME B; INTERLEUKIN 17; LYSOSOME ASSOCIATED MEMBRANE PROTEIN 1; PERFORIN; TRANSCRIPTOME;

EID: 84884810689     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1003504     Document Type: Article
Times cited : (125)

References (59)
  • 1
    • 77956252678 scopus 로고    scopus 로고
    • Regulation of CD8+ T cell responses to infection with parasitic protozoa
    • Jordan KA, Hunter CA, (2010) Regulation of CD8+ T cell responses to infection with parasitic protozoa. Experimental parasitology 126: 318-325.
    • (2010) Experimental Parasitology , vol.126 , pp. 318-325
    • Jordan, K.A.1    Hunter, C.A.2
  • 3
    • 69449095507 scopus 로고    scopus 로고
    • IL-17-producing CD8+ T lymphocytes from psoriasis skin plaques are cytotoxic effector cells that secrete Th17-related cytokines
    • Ortega C, Fernandez AS, Carrillo JM, Romero P, Molina IJ, et al. (2009) IL-17-producing CD8+ T lymphocytes from psoriasis skin plaques are cytotoxic effector cells that secrete Th17-related cytokines. Journal of leukocyte biology 86: 435-443.
    • (2009) Journal of Leukocyte Biology , vol.86 , pp. 435-443
    • Ortega, C.1    Fernandez, A.S.2    Carrillo, J.M.3    Romero, P.4    Molina, I.J.5
  • 4
    • 78649666553 scopus 로고    scopus 로고
    • Overrepresentation of IL-17A and IL-22 producing CD8 T cells in lesional skin suggests their involvement in the pathogenesis of psoriasis
    • Res PC, Piskin G, de Boer OJ, van der Loos CM, Teeling P, et al. (2010) Overrepresentation of IL-17A and IL-22 producing CD8 T cells in lesional skin suggests their involvement in the pathogenesis of psoriasis. PloS one 5: e14108.
    • (2010) PloS One , vol.5
    • Res, P.C.1    Piskin, G.2    de Boer, O.J.3    van der Loos, C.M.4    Teeling, P.5
  • 5
    • 0031830709 scopus 로고    scopus 로고
    • Coxsackievirus B3-induced myocarditis: perforin exacerbates disease, but plays no detectable role in virus clearance
    • Gebhard JR, Perry CM, Harkins S, Lane T, Mena I, et al. (1998) Coxsackievirus B3-induced myocarditis: perforin exacerbates disease, but plays no detectable role in virus clearance. The American journal of pathology 153: 417-428.
    • (1998) The American Journal of Pathology , vol.153 , pp. 417-428
    • Gebhard, J.R.1    Perry, C.M.2    Harkins, S.3    Lane, T.4    Mena, I.5
  • 6
    • 79958031319 scopus 로고    scopus 로고
    • Granzyme B expression by CD8+ T cells is required for the development of experimental cerebral malaria
    • Haque A, Best SE, Unosson K, Amante FH, de Labastida F, et al. (2011) Granzyme B expression by CD8+ T cells is required for the development of experimental cerebral malaria. Journal of immunology 186: 6148-6156.
    • (2011) Journal of Immunology , vol.186 , pp. 6148-6156
    • Haque, A.1    Best, S.E.2    Unosson, K.3    Amante, F.H.4    de Labastida, F.5
  • 7
    • 0037442024 scopus 로고    scopus 로고
    • Perforin-dependent brain-infiltrating cytotoxic CD8+ T lymphocytes mediate experimental cerebral malaria pathogenesis
    • Nitcheu J, Bonduelle O, Combadiere C, Tefit M, Seilhean D, et al. (2003) Perforin-dependent brain-infiltrating cytotoxic CD8+ T lymphocytes mediate experimental cerebral malaria pathogenesis. Journal of immunology 170: 2221-2228.
    • (2003) Journal of Immunology , vol.170 , pp. 2221-2228
    • Nitcheu, J.1    Bonduelle, O.2    Combadiere, C.3    Tefit, M.4    Seilhean, D.5
  • 8
    • 84861207371 scopus 로고    scopus 로고
    • CD8+ T-cells expressing interferon gamma or perforin play antagonistic roles in heart injury in experimental Trypanosoma cruzi-elicited cardiomyopathy
    • Silverio JC, Pereira IR, Cipitelli Mda C, Vinagre NF, Rodrigues MM, et al. (2012) CD8+ T-cells expressing interferon gamma or perforin play antagonistic roles in heart injury in experimental Trypanosoma cruzi-elicited cardiomyopathy. PLoS pathogens 8: e1002645.
    • (2012) PLoS Pathogens , vol.8
    • Silverio, J.C.1    Pereira, I.R.2    Cipitelli Mda, C.3    Vinagre, N.F.4    Rodrigues, M.M.5
  • 9
    • 79960392640 scopus 로고    scopus 로고
    • Leishmaniasis: complexity at the host-pathogen interface
    • Kaye P, Scott P, (2011) Leishmaniasis: complexity at the host-pathogen interface. Nat Rev Microbiol 9: 604-615.
    • (2011) Nat Rev Microbiol , vol.9 , pp. 604-615
    • Kaye, P.1    Scott, P.2
  • 10
    • 0036831673 scopus 로고    scopus 로고
    • The immunology of susceptibility and resistance to Leishmania major in mice
    • Sacks D, Noben-Trauth N, (2002) The immunology of susceptibility and resistance to Leishmania major in mice. Nature reviews Immunology 2: 845-858.
    • (2002) Nature Reviews Immunology , vol.2 , pp. 845-858
    • Sacks, D.1    Noben-Trauth, N.2
  • 11
    • 0037090268 scopus 로고    scopus 로고
    • CD8+ T cells are required for primary immunity in C57BL/6 mice following low-dose, intradermal challenge with Leishmania major
    • Belkaid Y, Von Stebut E, Mendez S, Lira R, Caler E, et al. (2002) CD8+ T cells are required for primary immunity in C57BL/6 mice following low-dose, intradermal challenge with Leishmania major. Journal of immunology 168: 3992-4000.
    • (2002) Journal of Immunology , vol.168 , pp. 3992-4000
    • Belkaid, Y.1    Von Stebut, E.2    Mendez, S.3    Lira, R.4    Caler, E.5
  • 12
    • 2942679337 scopus 로고    scopus 로고
    • Low dose Leishmania major promotes a transient T helper cell type 2 response that is down-regulated by interferon gamma-producing CD8+ T cells
    • Uzonna JE, Joyce KL, Scott P, (2004) Low dose Leishmania major promotes a transient T helper cell type 2 response that is down-regulated by interferon gamma-producing CD8+ T cells. The Journal of experimental medicine 199: 1559-1566.
    • (2004) The Journal of Experimental Medicine , vol.199 , pp. 1559-1566
    • Uzonna, J.E.1    Joyce, K.L.2    Scott, P.3
  • 14
    • 28444434128 scopus 로고    scopus 로고
    • Decreased in situ expression of interleukin-10 receptor is correlated with the exacerbated inflammatory and cytotoxic responses observed in mucosal leishmaniasis
    • Faria DR, Gollob KJ, Barbosa J Jr, Schriefer A, Machado PR, et al. (2005) Decreased in situ expression of interleukin-10 receptor is correlated with the exacerbated inflammatory and cytotoxic responses observed in mucosal leishmaniasis. Infection and immunity 73: 7853-7859.
    • (2005) Infection and Immunity , vol.73 , pp. 7853-7859
    • Faria, D.R.1    Gollob, K.J.2    Barbosa Jr., J.3    Schriefer, A.4    Machado, P.R.5
  • 15
    • 68249135239 scopus 로고    scopus 로고
    • Recruitment of CD8(+) T cells expressing granzyme A is associated with lesion progression in human cutaneous leishmaniasis
    • Faria DR, Souza PE, Duraes FV, Carvalho EM, Gollob KJ, et al. (2009) Recruitment of CD8(+) T cells expressing granzyme A is associated with lesion progression in human cutaneous leishmaniasis. Parasite immunology 31: 432-439.
    • (2009) Parasite Immunology , vol.31 , pp. 432-439
    • Faria, D.R.1    Souza, P.E.2    Duraes, F.V.3    Carvalho, E.M.4    Gollob, K.J.5
  • 16
  • 17
    • 0031278398 scopus 로고    scopus 로고
    • Parasite-driven in vitro human lymphocyte cytotoxicity against autologous infected macrophages from mucosal leishmaniasis
    • Brodskyn CI, Barral A, Boaventura V, Carvalho E, Barral-Netto M, (1997) Parasite-driven in vitro human lymphocyte cytotoxicity against autologous infected macrophages from mucosal leishmaniasis. Journal of immunology 159: 4467-4473.
    • (1997) Journal of Immunology , vol.159 , pp. 4467-4473
    • Brodskyn, C.I.1    Barral, A.2    Boaventura, V.3    Carvalho, E.4    Barral-Netto, M.5
  • 19
    • 84861793773 scopus 로고    scopus 로고
    • Gene set enrichment analysis: performance evaluation and usage guidelines
    • Hung JH, Yang TH, Hu Z, Weng Z, DeLisi C, (2012) Gene set enrichment analysis: performance evaluation and usage guidelines. Briefings in bioinformatics 13: 281-291.
    • (2012) Briefings in Bioinformatics , vol.13 , pp. 281-291
    • Hung, J.H.1    Yang, T.H.2    Hu, Z.3    Weng, Z.4    DeLisi, C.5
  • 20
    • 0142185336 scopus 로고    scopus 로고
    • Sensitive and viable identification of antigen-specific CD8+ T cells by a flow cytometric assay for degranulation
    • Betts MR, Brenchley JM, Price DA, De Rosa SC, Douek DC, et al. (2003) Sensitive and viable identification of antigen-specific CD8+ T cells by a flow cytometric assay for degranulation. Journal of immunological methods 281: 65-78.
    • (2003) Journal of Immunological Methods , vol.281 , pp. 65-78
    • Betts, M.R.1    Brenchley, J.M.2    Price, D.A.3    De Rosa, S.C.4    Douek, D.C.5
  • 21
    • 23944521372 scopus 로고    scopus 로고
    • Toward a novel experimental model of infection to study American cutaneous leishmaniasis caused by Leishmania braziliensis
    • de Moura TR, Novais FO, Oliveira F, Clarencio J, Noronha A, et al. (2005) Toward a novel experimental model of infection to study American cutaneous leishmaniasis caused by Leishmania braziliensis. Infection and immunity 73: 5827-5834.
    • (2005) Infection and Immunity , vol.73 , pp. 5827-5834
    • de Moura, T.R.1    Novais, F.O.2    Oliveira, F.3    Clarencio, J.4    Noronha, A.5
  • 22
    • 0031156475 scopus 로고    scopus 로고
    • Role of CD4+ T cells in pathogenesis associated with Leishmania amazonensis infection
    • Soong L, Chang CH, Sun J, Longley BJ Jr, Ruddle NH, et al. (1997) Role of CD4+ T cells in pathogenesis associated with Leishmania amazonensis infection. J Immunol 158: 5374-5383.
    • (1997) J Immunol , vol.158 , pp. 5374-5383
    • Soong, L.1    Chang, C.H.2    Sun, J.3    Longley Jr., B.J.4    Ruddle, N.H.5
  • 23
    • 41149118513 scopus 로고    scopus 로고
    • How dying cells alert the immune system to danger
    • Kono H, Rock KL, (2008) How dying cells alert the immune system to danger. Nature reviews Immunology 8: 279-289.
    • (2008) Nature Reviews Immunology , vol.8 , pp. 279-289
    • Kono, H.1    Rock, K.L.2
  • 25
    • 0025772187 scopus 로고
    • Establishment of resistance to Leishmania major infection in susceptible BALB/c mice requires parasite-specific CD8+ T cells
    • Muller I, Pedrazzini T, Kropf P, Louis J, Milon G, (1991) Establishment of resistance to Leishmania major infection in susceptible BALB/c mice requires parasite-specific CD8+ T cells. International immunology 3: 587-597.
    • (1991) International Immunology , vol.3 , pp. 587-597
    • Muller, I.1    Pedrazzini, T.2    Kropf, P.3    Louis, J.4    Milon, G.5
  • 26
    • 84874143982 scopus 로고    scopus 로고
    • CD8(+) T cells in leishmania infections: friends or foes?
    • Stager S, Rafati S, (2012) CD8(+) T cells in leishmania infections: friends or foes? Front Immunol 3: 5.
    • (2012) Front Immunol , vol.3 , pp. 5
    • Stager, S.1    Rafati, S.2
  • 27
    • 0030822043 scopus 로고    scopus 로고
    • Vaccination with DNA encoding the immunodominant LACK parasite antigen confers protective immunity to mice infected with Leishmania major
    • Gurunathan S, Sacks DL, Brown DR, Reiner SL, Charest H, et al. (1997) Vaccination with DNA encoding the immunodominant LACK parasite antigen confers protective immunity to mice infected with Leishmania major. J Exp Med 186: 1137-1147.
    • (1997) J Exp Med , vol.186 , pp. 1137-1147
    • Gurunathan, S.1    Sacks, D.L.2    Brown, D.R.3    Reiner, S.L.4    Charest, H.5
  • 28
    • 84863160177 scopus 로고    scopus 로고
    • Therapeutic vaccination with recombinant adenovirus reduces splenic parasite burden in experimental visceral leishmaniasis
    • Maroof A, Brown N, Smith B, Hodgkinson MR, Maxwell A, et al. (2012) Therapeutic vaccination with recombinant adenovirus reduces splenic parasite burden in experimental visceral leishmaniasis. The Journal of infectious diseases 205: 853-863.
    • (2012) The Journal of Infectious Diseases , vol.205 , pp. 853-863
    • Maroof, A.1    Brown, N.2    Smith, B.3    Hodgkinson, M.R.4    Maxwell, A.5
  • 29
    • 79959853005 scopus 로고    scopus 로고
    • TLR1/2 activation during heterologous prime-boost vaccination (DNA-MVA) enhances CD8+ T Cell responses providing protection against Leishmania (Viannia)
    • Jayakumar A, Castilho TM, Park E, Goldsmith-Pestana K, Blackwell JM, et al. (2011) TLR1/2 activation during heterologous prime-boost vaccination (DNA-MVA) enhances CD8+ T Cell responses providing protection against Leishmania (Viannia). PLoS neglected tropical diseases 5: e1204.
    • (2011) PLoS Neglected Tropical Diseases , vol.5
    • Jayakumar, A.1    Castilho, T.M.2    Park, E.3    Goldsmith-Pestana, K.4    Blackwell, J.M.5
  • 30
    • 77957934708 scopus 로고    scopus 로고
    • Vaccination with TAT-antigen fusion protein induces protective, CD8(+) T cell-mediated immunity against Leishmania major
    • Kronenberg K, Brosch S, Butsch F, Tada Y, Shibagaki N, et al. (2010) Vaccination with TAT-antigen fusion protein induces protective, CD8(+) T cell-mediated immunity against Leishmania major. The Journal of investigative dermatology 130: 2602-2610.
    • (2010) The Journal of Investigative Dermatology , vol.130 , pp. 2602-2610
    • Kronenberg, K.1    Brosch, S.2    Butsch, F.3    Tada, Y.4    Shibagaki, N.5
  • 31
    • 84862015359 scopus 로고    scopus 로고
    • High quality long-term CD4+ and CD8+ effector memory populations stimulated by DNA-LACK/MVA-LACK regimen in Leishmania major BALB/c model of infection
    • Sanchez-Sampedro L, Gomez CE, Mejias-Perez E, Sorzano CO, Esteban M, (2012) High quality long-term CD4+ and CD8+ effector memory populations stimulated by DNA-LACK/MVA-LACK regimen in Leishmania major BALB/c model of infection. PloS one 7: e38859.
    • (2012) PloS One , vol.7
    • Sanchez-Sampedro, L.1    Gomez, C.E.2    Mejias-Perez, E.3    Sorzano, C.O.4    Esteban, M.5
  • 32
    • 34547636180 scopus 로고    scopus 로고
    • Cytokines, signaling pathways, and effector molecules required for the control of Leishmania (Viannia) braziliensis in mice
    • Rocha FJ, Schleicher U, Mattner J, Alber G, Bogdan C, (2007) Cytokines, signaling pathways, and effector molecules required for the control of Leishmania (Viannia) braziliensis in mice. Infection and immunity 75: 3823-3832.
    • (2007) Infection and Immunity , vol.75 , pp. 3823-3832
    • Rocha, F.J.1    Schleicher, U.2    Mattner, J.3    Alber, G.4    Bogdan, C.5
  • 33
    • 84878588072 scopus 로고    scopus 로고
    • CD8+ Granzyme B+ T cells-mediated tissue injury versus CD4+ IFN-g+ T cells-mediated parasite killing in human cutaneous leishmaniasis
    • Silva C, Boaventura VS, Cardoso CR, Tavares NM, Lordelo MJ, et al. (2013) CD8+ Granzyme B+ T cells-mediated tissue injury versus CD4+ IFN-g+ T cells-mediated parasite killing in human cutaneous leishmaniasis. Journal of Investigative Dermatology In press.
    • (2013) Journal of Investigative Dermatology
    • Silva, C.1    Boaventura, V.S.2    Cardoso, C.R.3    Tavares, N.M.4    Lordelo, M.J.5
  • 34
    • 1842586922 scopus 로고    scopus 로고
    • CD8(+) T cells with parasite-specific cytotoxic activity and a Tc1 profile of cytokine and chemokine secretion develop in experimental visceral leishmaniasis
    • Tsagozis P, Karagouni E, Dotsika E, (2003) CD8(+) T cells with parasite-specific cytotoxic activity and a Tc1 profile of cytokine and chemokine secretion develop in experimental visceral leishmaniasis. Parasite immunology 25: 569-579.
    • (2003) Parasite Immunology , vol.25 , pp. 569-579
    • Tsagozis, P.1    Karagouni, E.2    Dotsika, E.3
  • 35
    • 84866489404 scopus 로고    scopus 로고
    • Inflammatory Monocytes Activate Memory CD8(+) T and Innate NK Lymphocytes Independent of Cognate Antigen during Microbial Pathogen Invasion
    • Soudja SM, Ruiz AL, Marie JC, Lauvau G, (2012) Inflammatory Monocytes Activate Memory CD8(+) T and Innate NK Lymphocytes Independent of Cognate Antigen during Microbial Pathogen Invasion. Immunity 37: 549-562.
    • (2012) Immunity , vol.37 , pp. 549-562
    • Soudja, S.M.1    Ruiz, A.L.2    Marie, J.C.3    Lauvau, G.4
  • 37
    • 0031571199 scopus 로고    scopus 로고
    • Presentation via the class I pathway by Leishmania amazonensis-infected macrophages of an endogenous leishmanial antigen to CD8+ T cells
    • Kima PE, Ruddle NH, McMahon-Pratt D, (1997) Presentation via the class I pathway by Leishmania amazonensis-infected macrophages of an endogenous leishmanial antigen to CD8+ T cells. Journal of immunology 159: 1828-1834.
    • (1997) Journal of Immunology , vol.159 , pp. 1828-1834
    • Kima, P.E.1    Ruddle, N.H.2    McMahon-Pratt, D.3
  • 38
    • 0029068371 scopus 로고
    • Leishmania infantum-specific T cell lines derived from asymptomatic dogs that lyse infected macrophages in a major histocompatibility complex-restricted manner
    • Pinelli E, Gonzalo RM, Boog CJ, Rutten VP, Gebhard D, et al. (1995) Leishmania infantum-specific T cell lines derived from asymptomatic dogs that lyse infected macrophages in a major histocompatibility complex-restricted manner. European journal of immunology 25: 1594-1600.
    • (1995) European Journal of Immunology , vol.25 , pp. 1594-1600
    • Pinelli, E.1    Gonzalo, R.M.2    Boog, C.J.3    Rutten, V.P.4    Gebhard, D.5
  • 39
    • 0033230519 scopus 로고    scopus 로고
    • Leishmania: naive human T cells sensitized with promastigote antigen and IL-12 develop into potent Th1 and CD8(+) cytotoxic effectors
    • Russo DM, Chakrabarti P, Higgins AY, (1999) Leishmania: naive human T cells sensitized with promastigote antigen and IL-12 develop into potent Th1 and CD8(+) cytotoxic effectors. Experimental parasitology 93: 161-170.
    • (1999) Experimental Parasitology , vol.93 , pp. 161-170
    • Russo, D.M.1    Chakrabarti, P.2    Higgins, A.Y.3
  • 40
    • 0025887827 scopus 로고
    • The interaction between CD8+ cytotoxic T cells and Leishmania-infected macrophages
    • Smith LE, Rodrigues M, Russell DG, (1991) The interaction between CD8+ cytotoxic T cells and Leishmania-infected macrophages. The Journal of experimental medicine 174: 499-505.
    • (1991) The Journal of Experimental Medicine , vol.174 , pp. 499-505
    • Smith, L.E.1    Rodrigues, M.2    Russell, D.G.3
  • 41
    • 33745978399 scopus 로고    scopus 로고
    • Regulatory T cells reversibly suppress cytotoxic T cell function independent of effector differentiation
    • Mempel TR, Pittet MJ, Khazaie K, Weninger W, Weissleder R, et al. (2006) Regulatory T cells reversibly suppress cytotoxic T cell function independent of effector differentiation. Immunity 25: 129-141.
    • (2006) Immunity , vol.25 , pp. 129-141
    • Mempel, T.R.1    Pittet, M.J.2    Khazaie, K.3    Weninger, W.4    Weissleder, R.5
  • 42
    • 30444457915 scopus 로고    scopus 로고
    • Apoptotic vesicles crossprime CD8 T cells and protect against tuberculosis
    • Winau F, Weber S, Sad S, de Diego J, Hoops SL, et al. (2006) Apoptotic vesicles crossprime CD8 T cells and protect against tuberculosis. Immunity 24: 105-117.
    • (2006) Immunity , vol.24 , pp. 105-117
    • Winau, F.1    Weber, S.2    Sad, S.3    de Diego, J.4    Hoops, S.L.5
  • 44
    • 0026536194 scopus 로고
    • Susceptibility of beta 2-microglobulin-deficient mice to Trypanosoma cruzi infection
    • Tarleton RL, Koller BH, Latour A, Postan M, (1992) Susceptibility of beta 2-microglobulin-deficient mice to Trypanosoma cruzi infection. Nature 356: 338-340.
    • (1992) Nature , vol.356 , pp. 338-340
    • Tarleton, R.L.1    Koller, B.H.2    Latour, A.3    Postan, M.4
  • 45
    • 29644446928 scopus 로고    scopus 로고
    • Adoptive immunotherapy against experimental visceral leishmaniasis with CD8+ T cells requires the presence of cognate antigen
    • Polley R, Stager S, Prickett S, Maroof A, Zubairi S, et al. (2006) Adoptive immunotherapy against experimental visceral leishmaniasis with CD8+ T cells requires the presence of cognate antigen. Infection and immunity 74: 773-776.
    • (2006) Infection and Immunity , vol.74 , pp. 773-776
    • Polley, R.1    Stager, S.2    Prickett, S.3    Maroof, A.4    Zubairi, S.5
  • 48
    • 0036884424 scopus 로고    scopus 로고
    • A blast from the past: clearance of apoptotic cells regulates immune responses
    • Savill J, Dransfield I, Gregory C, Haslett C, (2002) A blast from the past: clearance of apoptotic cells regulates immune responses. Nature reviews Immunology 2: 965-975.
    • (2002) Nature Reviews Immunology , vol.2 , pp. 965-975
    • Savill, J.1    Dransfield, I.2    Gregory, C.3    Haslett, C.4
  • 49
    • 84857640602 scopus 로고    scopus 로고
    • The alarmin interleukin-33 drives protective antiviral CD8(+) T cell responses
    • Bonilla WV, Frohlich A, Senn K, Kallert S, Fernandez M, et al. (2012) The alarmin interleukin-33 drives protective antiviral CD8(+) T cell responses. Science 335: 984-989.
    • (2012) Science , vol.335 , pp. 984-989
    • Bonilla, W.V.1    Frohlich, A.2    Senn, K.3    Kallert, S.4    Fernandez, M.5
  • 50
    • 0141998606 scopus 로고    scopus 로고
    • Molecular identification of a danger signal that alerts the immune system to dying cells
    • Shi Y, Evans JE, Rock KL, (2003) Molecular identification of a danger signal that alerts the immune system to dying cells. Nature 425: 516-521.
    • (2003) Nature , vol.425 , pp. 516-521
    • Shi, Y.1    Evans, J.E.2    Rock, K.L.3
  • 51
    • 70449367124 scopus 로고    scopus 로고
    • Cutaneous and mucocutaneous leishmaniasis
    • David CV, Craft N, (2009) Cutaneous and mucocutaneous leishmaniasis. Dermatologic therapy 22: 491-502.
    • (2009) Dermatologic Therapy , vol.22 , pp. 491-502
    • David, C.V.1    Craft, N.2
  • 52
    • 34247137487 scopus 로고    scopus 로고
    • Differential immune regulation of activated T cells between cutaneous and mucosal leishmaniasis as a model for pathogenesis
    • Carvalho LP, Passos S, Bacellar O, Lessa M, Almeida RP, et al. (2007) Differential immune regulation of activated T cells between cutaneous and mucosal leishmaniasis as a model for pathogenesis. Parasite immunology 29: 251-258.
    • (2007) Parasite Immunology , vol.29 , pp. 251-258
    • Carvalho, L.P.1    Passos, S.2    Bacellar, O.3    Lessa, M.4    Almeida, R.P.5
  • 53
    • 79951488203 scopus 로고    scopus 로고
    • Leishmania RNA virus controls the severity of mucocutaneous leishmaniasis
    • Ives A, Ronet C, Prevel F, Ruzzante G, Fuertes-Marraco S, et al. (2011) Leishmania RNA virus controls the severity of mucocutaneous leishmaniasis. Science 331: 775-778.
    • (2011) Science , vol.331 , pp. 775-778
    • Ives, A.1    Ronet, C.2    Prevel, F.3    Ruzzante, G.4    Fuertes-Marraco, S.5
  • 55
    • 2242423605 scopus 로고    scopus 로고
    • CD4+CD25+ regulatory T cells control Leishmania major persistence and immunity
    • Belkaid Y, Piccirillo CA, Mendez S, Shevach EM, Sacks DL, (2002) CD4+CD25+ regulatory T cells control Leishmania major persistence and immunity. Nature 420: 502-507.
    • (2002) Nature , vol.420 , pp. 502-507
    • Belkaid, Y.1    Piccirillo, C.A.2    Mendez, S.3    Shevach, E.M.4    Sacks, D.L.5
  • 56
    • 33847163271 scopus 로고    scopus 로고
    • CD4(+)CD25(-)Foxp3(-) Th1 cells are the source of IL-10-mediated immune suppression in chronic cutaneous leishmaniasis
    • Anderson CF, Oukka M, Kuchroo VJ, Sacks D, (2007) CD4(+)CD25(-)Foxp3(-) Th1 cells are the source of IL-10-mediated immune suppression in chronic cutaneous leishmaniasis. The Journal of experimental medicine 204: 285-297.
    • (2007) The Journal of Experimental Medicine , vol.204 , pp. 285-297
    • Anderson, C.F.1    Oukka, M.2    Kuchroo, V.J.3    Sacks, D.4
  • 59
    • 0035669096 scopus 로고    scopus 로고
    • A lipophosphoglycan-independent method for isolation of infective Leishmania metacyclic promastigotes by density gradient centrifugation
    • Spath GF, Beverley SM, (2001) A lipophosphoglycan-independent method for isolation of infective Leishmania metacyclic promastigotes by density gradient centrifugation. Experimental parasitology 99: 97-103.
    • (2001) Experimental Parasitology , vol.99 , pp. 97-103
    • Spath, G.F.1    Beverley, S.M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.