CD8+ T-cells expressing interferon gamma or perforin play antagonistic roles in heart injury in experimental trypanosoma cruzi-elicited cardiomyopathy

PLoS Pathogens

Volumn 8, Issue 4, 2012, Pages

  Silverio, Jaline Coutinho ^a   Pereira, Isabela Resende ^a   Cipitelli, Márcio da Costa ^a   Vinagre, Nathália Ferreira ^a   Rodrigues, Maurício Martins ^b   Gazzinelli, Ricardo Tostes ^a,c   Lannes Vieira, Joseli ^a  

^a INSTITUTO OSWALDO CRUZ   (Brazil)

^b FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

^c FEDERAL UNIVERSITY OF MINAS GERAIS   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

CREATINE KINASE MB; GAMMA INTERFERON; INTERLEUKIN 10; PERFORIN; PERFORIN, MOUSE; PORE FORMING CYTOTOXIC PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARDIOMYOPATHY; CD8+ T LYMPHOCYTE; CELL TRANSFER; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOTOXICITY; ELECTROCARDIOGRAM; FEMALE; HEART ARRHYTHMIA; HEART INJURY; HEART MUSCLE CELL; HEART MUSCLE POTENTIAL; HEART RATE; HEART WEIGHT; IN VIVO STUDY; LEUKOCYTE MIGRATION; MOUSE; MYOCARDITIS; NONHUMAN; PARASITEMIA; PARASITISM; PR INTERVAL; QRS COMPLEX; SPLEEN; TRYPANOSOMA CRUZI; ACUTE DISEASE; ANIMAL; BIOSYNTHESIS; CELL MOTION; CHAGAS DISEASE; GENE EXPRESSION REGULATION; GENETICS; HEART MUSCLE; IMMUNOLOGY; MALE; METABOLISM; MOUSE MUTANT; PATHOLOGY;

MUS; TRYPANOSOMA CRUZI;

ACUTE DISEASE; ANIMALS; CD8-POSITIVE T-LYMPHOCYTES; CELL MOVEMENT; CHAGAS CARDIOMYOPATHY; FEMALE; GENE EXPRESSION REGULATION; INTERFERON-GAMMA; MALE; MICE; MICE, KNOCKOUT; MYOCARDIUM; MYOCYTES, CARDIAC; PORE FORMING CYTOTOXIC PROTEINS; TRYPANOSOMA CRUZI;

EID: 84861207371     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1002645     Document Type: Article

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