메뉴 건너뛰기




Volumn 18, Issue 8, 2013, Pages 668-673

Association between leptin gene G-2548A polymorphism with metabolic syndrome

Author keywords

2548G A polymorphism; Leptin; Metabolic syndrome

Indexed keywords

GLUCOSE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LEPTIN; TRIACYLGLYCEROL;

EID: 84884760275     PISSN: 17351995     EISSN: 17357136     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (12)

References (38)
  • 1
    • 0842277242 scopus 로고    scopus 로고
    • Definition of metabolic syndrome: Report of the National Heart, Lung, and Blood Institute/ American Heart Association conference on scientifc issues related to defnition
    • American Heart Association, et al
    • Grundy SM, Brewer HB Jr, Cleeman JI, Smith SC Jr, Lenfant C, American Heart Association, et al. Definition of metabolic syndrome: Report of the National Heart, Lung, and Blood Institute/ American Heart Association conference on scientifc issues related to defnition. Circulation 2004;109:433-438.
    • (2004) Circulation , vol.109 , pp. 433-438
    • Grundy, S.M.1    Brewer Jr., H.B.2    Cleeman, J.I.3    Smith Jr., S.C.4    Lenfant, C.5
  • 2
    • 59049085845 scopus 로고    scopus 로고
    • Genetics of the cardiometabolic syndrome: New insights and therapeutic implications
    • Sookoian S, Pirola CJ. Genetics of the cardiometabolic syndrome: New insights and therapeutic implications. Ther Adv Cardiovasc Dis 2007;1:37-47.
    • (2007) Ther Adv Cardiovasc Dis , vol.1 , pp. 37-47
    • Sookoian, S.1    Pirola, C.J.2
  • 3
    • 38449120612 scopus 로고    scopus 로고
    • Genetic variants within the LPIN1 gene, encoding lipin, are infuencing phenotypes of the metabolic syndrome in humans
    • Wiedmann S, Fischer M, Koehler M, Neureuther K, Riegger G, Doering A, et al. Genetic variants within the LPIN1 gene, encoding lipin, are infuencing phenotypes of the metabolic syndrome in humans. Diabetes 2008;57:209-217.
    • (2008) Diabetes , vol.57 , pp. 209-217
    • Wiedmann, S.1    Fischer, M.2    Koehler, M.3    Neureuther, K.4    Riegger, G.5    Doering, A.6
  • 4
    • 77956869772 scopus 로고    scopus 로고
    • Infammation, a link between obesity and cardiovascular disease
    • Wang Z, Nakayama T. Infammation, a link between obesity and cardiovascular disease. Mediators Infamm 2010;2010:535918.
    • (2010) Mediators Infamm 2010 , pp. 535918
    • Wang, Z.1    Nakayama, T.2
  • 5
    • 36348982246 scopus 로고    scopus 로고
    • One common polymorphism of cholesteryl ester transfer protein gene in Iranian subjects with and without primary hypertriglyceridemia
    • Ghasabeh TH, Firoozrai M, Zonouz AE, Radmehr H, Zavarehee A, Paoli M. One common polymorphism of cholesteryl ester transfer protein gene in Iranian subjects with and without primary hypertriglyceridemia. Pak J Biol Sci 2007;10:4224-4229.
    • (2007) Pak J Biol Sci , vol.10 , pp. 4224-4229
    • Ghasabeh, T.H.1    Firoozrai, M.2    Zonouz, A.E.3    Radmehr, H.4    Zavarehee, A.5    Paoli, M.6
  • 6
    • 77953165868 scopus 로고    scopus 로고
    • Butyrylcholinesterase K variant and the APOE-epsilon 4 allele work in synergy to increase the risk of coronary artery disease especially in diabetic patients
    • Vaisi-Raygani A, Rahimi Z, Tavilani H, Pourmotabbed T. Butyrylcholinesterase K variant and the APOE-epsilon 4 allele work in synergy to increase the risk of coronary artery disease especially in diabetic patients. Mol Biol Rep 2010;37:2083-2091.
    • (2010) Mol Biol Rep , vol.37 , pp. 2083-2091
    • Vaisi-Raygani, A.1    Rahimi, Z.2    Tavilani, H.3    Pourmotabbed, T.4
  • 7
    • 79951581875 scopus 로고    scopus 로고
    • The frequency of factor V Leiden mutation, ACE gene polymorphism, serum ACE activity and response to ACE inhibitor and angiotensin II receptor antagonist drugs in Iranians type II diabetic patients with microalbuminuria
    • Rahimi Z, Felehgari V, Rahimi M, Mozafari H, Yari K, Vaisi-Raygani A, et al. The frequency of factor V Leiden mutation, ACE gene polymorphism, serum ACE activity and response to ACE inhibitor and angiotensin II receptor antagonist drugs in Iranians type II diabetic patients with microalbuminuria. Mol Biol Rep 2011;38:2117-2123.
    • (2011) Mol Biol Rep , vol.38 , pp. 2117-2123
    • Rahimi, Z.1    Felehgari, V.2    Rahimi, M.3    Mozafari, H.4    Yari, K.5    Vaisi-Raygani, A.6
  • 8
    • 54549108987 scopus 로고    scopus 로고
    • Association between cholesteryl ester transfer protein Taq1B polymorphism with lipid levels in primary hyperlipidemic patients
    • Ghasabeh TH, Firoozrai M, Zonouz AE, Radmehr H, Zavarehee A, Paoli M. Association between cholesteryl ester transfer protein Taq1B polymorphism with lipid levels in primary hyperlipidemic patients. Eur J Lipid Sci Technol 2008;110:225-231.
    • (2008) Eur J Lipid Sci Technol , vol.110 , pp. 225-231
    • Ghasabeh, T.H.1    Firoozrai, M.2    Zonouz, A.E.3    Radmehr, H.4    Zavarehee, A.5    Paoli, M.6
  • 9
    • 67649643640 scopus 로고    scopus 로고
    • Taq1B polymorphism of cholesteryl ester transfer protein (CETP) gene in primary combined hyperlipidaemia
    • Hassanzadeh T, Firoozrai M, Zonouz AE, Zavarehee A, Paoli M. Taq1B polymorphism of cholesteryl ester transfer protein (CETP) gene in primary combined hyperlipidaemia. Indian J Med Res 2009;129:293-8.
    • (2009) Indian J Med Res , vol.129 , pp. 293-298
    • Hassanzadeh, T.1    Firoozrai, M.2    Zonouz, A.E.3    Zavarehee, A.4    Paoli, M.5
  • 10
    • 84856984057 scopus 로고    scopus 로고
    • Association between cholestryl ester transfer protein D442G polymorphism on serum lipid levels and CETP activity in hypercholesterolemic patients
    • Barkhordari A, Hassanzadeh T, Saidiam M, Esmaeili R, Paoli M. Association between cholestryl ester transfer protein D442G polymorphism on serum lipid levels and CETP activity in hypercholesterolemic patients. TUMJ 2012;69:737-743.
    • (2012) TUMJ , vol.69 , pp. 737-743
    • Barkhordari, A.1    Hassanzadeh, T.2    Saidiam, M.3    Esmaeili, R.4    Paoli, M.5
  • 11
    • 0033794850 scopus 로고    scopus 로고
    • Human leptin: From an adipocyte hormone to an endocrine mediator
    • Wauters M, Considine RV, Van Gaal LF. Human leptin: From an adipocyte hormone to an endocrine mediator. Eur J Endocrinol 2000;143:293-311.
    • (2000) Eur J Endocrinol , vol.143 , pp. 293-311
    • Wauters, M.1    Considine, R.V.2    van Gaal, L.F.3
  • 13
    • 19344373130 scopus 로고    scopus 로고
    • Human leptin: An adipocyte hormone with weight-regulatory and endocrine functions
    • Considine RV. Human leptin: An adipocyte hormone with weight-regulatory and endocrine functions. Semin Vasc Med 2005;5:15-24.
    • (2005) Semin Vasc Med , vol.5 , pp. 15-24
    • Considine, R.V.1
  • 14
    • 30044434035 scopus 로고    scopus 로고
    • Intracellular signalling pathways activated by leptin
    • Frühbeck G. Intracellular signalling pathways activated by leptin. Biochem J 2006;393:7-20.
    • (2006) Biochem J , vol.393 , pp. 7-20
    • Frühbeck, G.1
  • 15
    • 78650802927 scopus 로고    scopus 로고
    • The polymorphism -2548G/A in leptin and severity of chronic obstructive pulmonary disease
    • Ye XW, Xiao M, Ye J, Zhang XY, Xiao J, Feng YL, et al. The polymorphism -2548G/A in leptin and severity of chronic obstructive pulmonary disease. Int J Immunogenet 2011;38:45-50.
    • (2011) Int J Immunogenet , vol.38 , pp. 45-50
    • Ye, X.W.1    Xiao, M.2    Ye, J.3    Zhang, X.Y.4    Xiao, J.5    Feng, Y.L.6
  • 16
    • 0028845877 scopus 로고
    • Leptin levels in human and rodent: Measurement of plasma leptin and ob RNA in obese and weight-reduced subjects
    • Mafei M, Halaas J, Ravussin E, Pratley RE, Lee GH, Zhang Y, et al. Leptin levels in human and rodent: Measurement of plasma leptin and ob RNA in obese and weight-reduced subjects. Nat Med 1995;1:1155-1161.
    • (1995) Nat Med , vol.1 , pp. 1155-1161
    • Mafei, M.1    Halaas, J.2    Ravussin, E.3    Pratley, R.E.4    Lee, G.H.5    Zhang, Y.6
  • 17
    • 0031892748 scopus 로고    scopus 로고
    • Novel polymorphisms in the 5' region of the LEP gene: Association with leptin levels and response to low-calorie diet in human obesity
    • Mammès O, Betoulle D, Aubert R, Giraud V, Tuzet S, Petiet A, et al. Novel polymorphisms in the 5' region of the LEP gene: Association with leptin levels and response to low-calorie diet in human obesity. Diabetes 1998;47:487-489.
    • (1998) Diabetes , vol.47 , pp. 487-489
    • Mammès, O.1    Betoulle, D.2    Aubert, R.3    Giraud, V.4    Tuzet, S.5    Petiet, A.6
  • 18
    • 0034527931 scopus 로고    scopus 로고
    • Association of the G-2548A polymorphism in the 5' region of the LEP gene with overweight
    • Mammès O, Betoulle D, Aubert R, Herbeth B, Siest G, Fumeron F. Association of the G-2548A polymorphism in the 5' region of the LEP gene with overweight. Ann Hum Genet 2000;64:391-394.
    • (2000) Ann Hum Genet , vol.64 , pp. 391-394
    • Mammès, O.1    Betoulle, D.2    Aubert, R.3    Herbeth, B.4    Siest, G.5    Fumeron, F.6
  • 19
    • 0036628931 scopus 로고    scopus 로고
    • A polymorphism in the leptin promoter region (-2548 G/A) influences gene expression and adipose tissue secretion of leptin
    • Hofstedt J, Eriksson P, Motagui-Tabar S, Arner P. A polymorphism in the leptin promoter region (-2548 G/A) influences gene expression and adipose tissue secretion of leptin. Horm Metab Res 2002;34:355-359.
    • (2002) Horm Metab Res , vol.34 , pp. 355-359
    • Hofstedt, J.1    Eriksson, P.2    Motagui-Tabar, S.3    Arner, P.4
  • 20
    • 0033661267 scopus 로고    scopus 로고
    • A common promoter variant of the leptin gene is associated with changes in the relationship between serum leptin and fat mass in obese girls
    • Le Stunf C, Le Bihan C, Schork NJ, Bougnères P. A common promoter variant of the leptin gene is associated with changes in the relationship between serum leptin and fat mass in obese girls. Diabetes 2000;49:2196-200.
    • (2000) Diabetes , vol.49 , pp. 2196-2200
    • Le Stunf, C.1    Le Bihan, C.2    Schork, N.J.3    Bougnères, P.4
  • 21
    • 0032871802 scopus 로고    scopus 로고
    • Sequence variants in the 5' fanking region of the leptin gene are associated with obesity in women
    • Li WD, Reed DR, Lee JH, Xu W, Kilker RL, Sodam BR, et al. Sequence variants in the 5' fanking region of the leptin gene are associated with obesity in women. Ann Hum Genet 1999;63:227-234.
    • (1999) Ann Hum Genet , vol.63 , pp. 227-234
    • Li, W.D.1    Reed, D.R.2    Lee, J.H.3    Xu, W.4    Kilker, R.L.5    Sodam, B.R.6
  • 22
    • 78149249515 scopus 로고    scopus 로고
    • Appropriate definition of metabolic syndrome among Iranian adults: Report of the Iranian national committee of obesity
    • Azizi F, Hadaegh F, Khalili D, Esteghamati A, Hosseinpanah F, Delavari A, et al. Appropriate definition of metabolic syndrome among Iranian adults: Report of the Iranian national committee of obesity. Arch Iran Med 2010;13:426-428.
    • (2010) Arch Iran Med , vol.13 , pp. 426-428
    • Azizi, F.1    Hadaegh, F.2    Khalili, D.3    Esteghamati, A.4    Hosseinpanah, F.5    Delavari, A.6
  • 23
    • 0033782028 scopus 로고    scopus 로고
    • Leptin in the regulation of immunity, inflammation, and hematopoiesis
    • Fantuzzi G, Faggioni R. Leptin in the regulation of immunity, inflammation, and hematopoiesis. J Leukoc Biol 2000;68:437-446.
    • (2000) J Leukoc Biol , vol.68 , pp. 437-446
    • Fantuzzi, G.1    Faggioni, R.2
  • 24
    • 0034457109 scopus 로고    scopus 로고
    • Leptin and aging: Correlation with endocrine changes in male and female healthy adult populations of diferent body weights
    • Isidori AM, Strollo F, Morè M, Caprio M, Aversa A, Moreti C, et al. Leptin and aging: Correlation with endocrine changes in male and female healthy adult populations of diferent body weights. J Clin Endocrinol Metab 2000;85:1954-1962.
    • (2000) J Clin Endocrinol Metab , vol.85 , pp. 1954-1962
    • Isidori, A.M.1    Strollo, F.2    Morè, M.3    Caprio, M.4    Aversa, A.5    Moreti, C.6
  • 27
    • 63649124935 scopus 로고    scopus 로고
    • Association of G-2548A LEP polymorphism with plasma leptin levels in Tunisian obese patients
    • Ben Ali S, Kallel A, Ftouhi B, Sediri Y, Feki M, Slimane H, et al. Association of G-2548A LEP polymorphism with plasma leptin levels in Tunisian obese patients. Clin Biochem 2009;42:584-588.
    • (2009) Clin Biochem , vol.42 , pp. 584-588
    • Ben Ali, S.1    Kallel, A.2    Ftouhi, B.3    Sediri, Y.4    Feki, M.5    Slimane, H.6
  • 28
    • 72949119318 scopus 로고    scopus 로고
    • Leptin G-2548A and leptin receptor Q223R gene polymorphisms are not associated with obesity in Romanian subjects
    • Constantin A, Costache G, Sima AV, Glavce CS, Vladica M, Popov DL. Leptin G-2548A and leptin receptor Q223R gene polymorphisms are not associated with obesity in Romanian subjects. Biochem Biophys Res Commun 2010;391:282-286.
    • (2010) Biochem Biophys Res Commun , vol.391 , pp. 282-286
    • Constantin, A.1    Costache, G.2    Sima, A.V.3    Glavce, C.S.4    Vladica, M.5    Popov, D.L.6
  • 31
    • 38349080768 scopus 로고    scopus 로고
    • Mechanism of leptin expression in breast cancer cells: Role of hypoxia-inducible factor-1alpha
    • Cascio S, Bartella V, Auriemma A, Johannes GJ, Russo A, Giordano A, et al. Mechanism of leptin expression in breast cancer cells: Role of hypoxia-inducible factor-1alpha. Oncogene 2008;27:540-547.
    • (2008) Oncogene , vol.27 , pp. 540-547
    • Cascio, S.1    Bartella, V.2    Auriemma, A.3    Johannes, G.J.4    Russo, A.5    Giordano, A.6
  • 33
    • 0345599015 scopus 로고    scopus 로고
    • S100C/A11 is a key mediator of Ca (2+)-induced growth inhibition of human epidermal keratinocytes
    • Sakaguchi M, Miyazaki M, Takaishi M, Sakaguchi Y, Makino E, Kataoka N, et al. S100C/A11 is a key mediator of Ca (2+)-induced growth inhibition of human epidermal keratinocytes. J Cell Biol 2003;163:825-835.
    • (2003) J Cell Biol , vol.163 , pp. 825-835
    • Sakaguchi, M.1    Miyazaki, M.2    Takaishi, M.3    Sakaguchi, Y.4    Makino, E.5    Kataoka, N.6
  • 34
    • 67650070739 scopus 로고    scopus 로고
    • Functional analysis of the -2548G/A leptin gene polymorphism in breast cancer cells
    • Terrasi M, Fiorio E, Mercanti A, Koda M, Moncada CA, Sulkowski S, et al. Functional analysis of the -2548G/A leptin gene polymorphism in breast cancer cells. Int J Cancer 2009;125:1038-1044.
    • (2009) Int J Cancer , vol.125 , pp. 1038-1044
    • Terrasi, M.1    Fiorio, E.2    Mercanti, A.3    Koda, M.4    Moncada, C.A.5    Sulkowski, S.6
  • 35
    • 38349173105 scopus 로고    scopus 로고
    • Nucleolin regulates c-Jun/Sp1-dependent transcriptional activation of cPLA2alpha in phorbol ester-treated non-small cell lung cancer A549 cells
    • Tsou JH, Chang KY, Wang WC, Tseng JT, Su WC, Hung LY, et al. Nucleolin regulates c-Jun/Sp1-dependent transcriptional activation of cPLA2alpha in phorbol ester-treated non-small cell lung cancer A549 cells. Nucleic Acids Res 2008;36:217-227.
    • (2008) Nucleic Acids Res , vol.36 , pp. 217-227
    • Tsou, J.H.1    Chang, K.Y.2    Wang, W.C.3    Tseng, J.T.4    Su, W.C.5    Hung, L.Y.6
  • 38
    • 33748970803 scopus 로고    scopus 로고
    • Leptin and atherosclerosis
    • Beltowski J. Leptin and atherosclerosis. Atherosclerosis 2006;189:47-60.
    • (2006) Atherosclerosis , vol.189 , pp. 47-60
    • Beltowski, J.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.