A novel alcohol-sensitive position in the N-methyl-D-aspartate receptor GluN2A subunit M3 domain regulates agonist affinity and ion channel gating

Molecular Pharmacology

Volumn 84, Issue 4, 2013, Pages 501-510

  Ren, Hong ^a   Zhao, Yulin ^a   Wu, Man ^a   Peoples, Robert W ^a  

^a MARQUETTE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALCOHOL; GLUTAMIC ACID; ION CHANNEL; ISOLEUCINE; LEUCINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 2A; N METHYL DEXTRO ASPARTIC ACID RECEPTOR STIMULATING AGENT;

AMINO ACID SUBSTITUTION; ARTICLE; CHANNEL GATING; DESENSITIZATION; HUMAN; HUMAN CELL; IC 50; ISOMERISM; MUTANT; MUTATION; PRIORITY JOURNAL; PROTEIN DOMAIN; RECEPTOR AFFINITY; RECEPTOR SENSITIVITY; REGULATORY MECHANISM; STEADY STATE;

AMINO ACID SEQUENCE; DOSE-RESPONSE RELATIONSHIP, DRUG; ETHANOL; EXCITATORY AMINO ACID AGONISTS; HEK293 CELLS; HUMANS; ION CHANNEL GATING; MOLECULAR SEQUENCE DATA; MUTATION; PROTEIN BINDING; PROTEIN SUBUNITS; RECEPTORS, N-METHYL-D-ASPARTATE;

EID: 84884695488     PISSN: 0026895X     EISSN: 15210111     Source Type: Journal    
DOI: 10.1124/mol.113.085993     Document Type: Article

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