Differential actions of ethanol and trichloroethanol at sites in the M3 and M4 domains of the NMDA receptor GluN2A (NR2A) subunit

British Journal of Pharmacology

Volumn 158, Issue 5, 2009, Pages 1395-1404

  Salous, A K ^a   Ren, H ^a   Lamb, K A ^a   Hu, X Q ^a   Lipsky, R H ^b,c   Peoples, R W ^a  

^a MARQUETTE UNIVERSITY   (United States)

^b INOVA FAIRFAX HOSPITAL   (United States)

^c GEORGE MASON UNIVERSITY   (United States)

Author keywords

Alcohol; Electrophysiology; Glutamate receptor; Membrane associated domains; Mutant; Sedative hypnotic

Indexed keywords

ALANINE; ALCOHOL; GLUTAMIC ACID; GLYCINE; METHIONINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 2A; OCTANOL; PHENYLALANINE; PROTEIN SUBUNIT; TRICHLOROETHANOL;

AMINO ACID SUBSTITUTION; ARTICLE; BINDING SITE; CELL STRAIN HEK293; CONTROLLED STUDY; HUMAN; HUMAN CELL; HYDROPHOBICITY; IC 50; PATCH CLAMP; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; PROTEIN DOMAIN; SITE DIRECTED MUTAGENESIS;

CELL LINE; ETHANOL; ETHYLENE CHLOROHYDRIN; HUMANS; MUTATION; PROTEIN STRUCTURE, TERTIARY; PROTEIN SUBUNITS; RECEPTORS, N-METHYL-D-ASPARTATE;

EID: 70849113229     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/j.1476-5381.2009.00397.x     Document Type: Article

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