메뉴 건너뛰기




Volumn 738, Issue 2, 1996, Pages 249-256

Single-channel and whole-cell analysis of ethanol inhibition of NMDA-activated currents in cultured mouse cortical and hippocampal neurons

Author keywords

ethanol; inbred strain C57BL 6; kinetic analysis; mouse; N methyl D aspartate; single channel recording; whole cell recording

Indexed keywords

ALCOHOL; N METHYL DEXTRO ASPARTIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR;

EID: 0030569408     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(96)00780-9     Document Type: Article
Times cited : (96)

References (49)
  • 1
    • 0023876916 scopus 로고
    • N-methyl-D-aspartate-activated channels of mouse central neurons in magnesium-free solutions
    • [1] Ascher, P., Bregestovski, P. and Nowak, L., N-methyl-D-aspartate-activated channels of mouse central neurons in magnesium-free solutions, J. Physiol. (Lond.), 399 (1988) 207-226.
    • (1988) J. Physiol. (Lond.) , vol.399 , pp. 207-226
    • Ascher, P.1    Bregestovski, P.2    Nowak, L.3
  • 2
    • 0029074490 scopus 로고
    • Ethanol inhibition of recombinant heteromeric NMDA channels in the presence and absence of modulators
    • [2] Chu, B., Anantharam, V. and Treistman, S.N., Ethanol inhibition of recombinant heteromeric NMDA channels in the presence and absence of modulators, J. Neurochem., 65 (1995) 140-148.
    • (1995) J. Neurochem. , vol.65 , pp. 140-148
    • Chu, B.1    Anantharam, V.2    Treistman, S.N.3
  • 3
    • 0024829451 scopus 로고
    • Excitatory amino acid receptors in the vertebrate central nervous system
    • [3] Collingridge, G.L. and Lester, R.A.J., Excitatory amino acid receptors in the vertebrate central nervous system, Pharmacol. Rev., 40 (1989) 143-210.
    • (1989) Pharmacol. Rev. , vol.40 , pp. 143-210
    • Collingridge, G.L.1    Lester, R.A.J.2
  • 4
    • 0022272338 scopus 로고
    • Fast events in single-channel currents activated by acetylcholine and its analogues at the frog muscle end-plate
    • [4] Colquhoun, D. and Sakmann, B., Fast events in single-channel currents activated by acetylcholine and its analogues at the frog muscle end-plate, J. Physiol. (Lond.), 369 (1985) 501-557.
    • (1985) J. Physiol. (Lond.) , vol.369 , pp. 501-557
    • Colquhoun, D.1    Sakmann, B.2
  • 5
    • 0027466062 scopus 로고
    • The role of NMDA receptors in information processing
    • [5] Daw, N.W., Stein, P.S.G. and Fox, K., The role of NMDA receptors in information processing, Annu. Rev. Neurosci., 16 (1993) 207-222.
    • (1993) Annu. Rev. Neurosci. , vol.16 , pp. 207-222
    • Daw, N.W.1    Stein, P.S.G.2    Fox, K.3
  • 6
    • 0018001339 scopus 로고
    • Simultaneous analysis of families of sigmoidal curves: Application to bioassay, radioligand assay, and physiological dose-response curves
    • [6] De Lean, A., Munson, P.J. and Rodbard, D., Simultaneous analysis of families of sigmoidal curves: application to bioassay, radioligand assay, and physiological dose-response curves, Am. J. Physiol., 235 (1978) E97-E102.
    • (1978) Am. J. Physiol. , vol.235
    • De Lean, A.1    Munson, P.J.2    Rodbard, D.3
  • 8
    • 0023856147 scopus 로고
    • Slow excitatory postsynaptic currents mediated by N-methyl-D-aspartate receptors on cultured mouse central neurones
    • [8] Forsythe, I.D. and Westbrook, G.L., Slow excitatory postsynaptic currents mediated by N-methyl-D-aspartate receptors on cultured mouse central neurones, J. Physiol. (Lond.), 396 (1988) 515-533.
    • (1988) J. Physiol. (Lond.) , vol.396 , pp. 515-533
    • Forsythe, I.D.1    Westbrook, G.L.2
  • 9
    • 0026596478 scopus 로고
    • Molecular neurobiology of glutamate receptors
    • [9] Gasic, G.P. and Hollmann, M., Molecular neurobiology of glutamate receptors, Annu. Rev. Physiol., 54 (1992) 507-536.
    • (1992) Annu. Rev. Physiol. , vol.54 , pp. 507-536
    • Gasic, G.P.1    Hollmann, M.2
  • 11
    • 0024426896 scopus 로고
    • Inhibition of N-methyl-D-aspartate(NMDA) and L-glutamate-induced noradrenaline and acetylcholine release in the rat brain by ethanol
    • [11] Göthert, M. and Fink, K., Inhibition of N-methyl-D-aspartate(NMDA) and L-glutamate-induced noradrenaline and acetylcholine release in the rat brain by ethanol, Naunyn Schmiedebergs Arch. Pharmacol., 340 (1989) 516-521.
    • (1989) Naunyn Schmiedebergs Arch. Pharmacol. , vol.340 , pp. 516-521
    • Göthert, M.1    Fink, K.2
  • 12
    • 0028075026 scopus 로고
    • Emerging neurochemical concepts in the actions of ethanol at ligand-gated ion channels
    • [12] Grant, K.A., Emerging neurochemical concepts in the actions of ethanol at ligand-gated ion channels, Behav. Pharmacol., 5 (1994) 383-404.
    • (1994) Behav. Pharmacol. , vol.5 , pp. 383-404
    • Grant, K.A.1
  • 13
    • 0028269524 scopus 로고
    • Acute tolerance to ethanol inhibition of NMDA-mediated EPSPs in the CA1 region of the rat hippocampus
    • [13] Grover, C.A., Frye, G.D. and Griffith, W.H., Acute tolerance to ethanol inhibition of NMDA-mediated EPSPs in the CA1 region of the rat hippocampus, Brain Res., 642 (1994) 70-76.
    • (1994) Brain Res. , vol.642 , pp. 70-76
    • Grover, C.A.1    Frye, G.D.2    Griffith, W.H.3
  • 14
    • 0019441262 scopus 로고
    • Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches
    • [14] Hamill, O.P., Marty, A., Neher, E., Sakmann, B. and Sigworth, F.J., Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches, Pflügers Arch., 391 (1981) 85-100.
    • (1981) Pflügers Arch. , vol.391 , pp. 85-100
    • Hamill, O.P.1    Marty, A.2    Neher, E.3    Sakmann, B.4    Sigworth, F.J.5
  • 17
    • 0027717219 scopus 로고
    • Ethanol inhibits glutamate-induced currents in heteromeric NMDA receptor subtypes
    • [17] Kuner, T., Schoepfer, R. and Korpi, E.R., Ethanol inhibits glutamate-induced currents in heteromeric NMDA receptor subtypes, NeuroReport, 5 (1993) 297-300.
    • (1993) NeuroReport , vol.5 , pp. 297-300
    • Kuner, T.1    Schoepfer, R.2    Korpi, E.R.3
  • 18
    • 0024601948 scopus 로고
    • Ethanol potentiates and blocks NMDA-activated single-channel currents in rat hippocampal pyramidal cells
    • [18] Lima-Landman, M.T.R. and Albuquerque, E.X., Ethanol potentiates and blocks NMDA-activated single-channel currents in rat hippocampal pyramidal cells, FEBS Lett., 247 (1989) 61-67.
    • (1989) FEBS Lett. , vol.247 , pp. 61-67
    • Lima-Landman, M.T.R.1    Albuquerque, E.X.2
  • 19
    • 0026569410 scopus 로고
    • Models of neuronal injury in AIDS: Another role for the NMDA receptor?
    • [19] Lipton, S.A., Models of neuronal injury in AIDS: another role for the NMDA receptor?, Trends Pharmacol. Sci., 15 (1992) 75-79.
    • (1992) Trends Pharmacol. Sci. , vol.15 , pp. 75-79
    • Lipton, S.A.1
  • 20
    • 0028762647 scopus 로고
    • Excitatory amino acids as a final common pathway for neurologic disorders
    • [20] Lipton, S.A. and Rosenberg, P.A., Excitatory amino acids as a final common pathway for neurologic disorders, New Engl. J. Med., 330 (1994) 613-622.
    • (1994) New Engl. J. Med. , vol.330 , pp. 613-622
    • Lipton, S.A.1    Rosenberg, P.A.2
  • 21
    • 0028998695 scopus 로고
    • Developmental decrease in ethanol inhibition of N-methyl-D-aspartate receptors in rat neocortical neurons: Relation to the actions of ifenprodil
    • [21] Lovinger, D.M., Developmental decrease in ethanol inhibition of N-methyl-D-aspartate receptors in rat neocortical neurons: Relation to the actions of ifenprodil, J. Pharmacol. Exp. Ther., 274 (1995) 164-172.
    • (1995) J. Pharmacol. Exp. Ther. , vol.274 , pp. 164-172
    • Lovinger, D.M.1
  • 23
    • 0024535962 scopus 로고
    • Ethanol inhibits NMDA-activated ion current in hippocampal neurons
    • [23] Lovinger, D.M., White, G. and Weight, F.F., Ethanol inhibits NMDA-activated ion current in hippocampal neurons, Science, 243 (1989) 1721-1724.
    • (1989) Science , vol.243 , pp. 1721-1724
    • Lovinger, D.M.1    White, G.2    Weight, F.F.3
  • 24
    • 4243567027 scopus 로고
    • Ethanol (EtOH) inhibition of NMDA-activated ion current is not voltage-dependent and EtOH does not interact with other binding sites on the NMDA receptor/ionophore complex
    • [24] Lovinger, D.M., White, G. and Weight, F.F., Ethanol (EtOH) inhibition of NMDA-activated ion current is not voltage-dependent and EtOH does not interact with other binding sites on the NMDA receptor/ionophore complex, FASEB J., 4 (1990) A678.
    • (1990) FASEB J. , vol.4
    • Lovinger, D.M.1    White, G.2    Weight, F.F.3
  • 25
    • 0025407309 scopus 로고
    • NMDA receptor-mediated synaptic excitation selectively inhibited by ethanol in hippocampal slice from adult rat
    • [25] Lovinger, D.M., White, G. and Weight, F.F., NMDA receptor-mediated synaptic excitation selectively inhibited by ethanol in hippocampal slice from adult rat, J. Neurosci., 10 (1990) 1372-1379.
    • (1990) J. Neurosci. , vol.10 , pp. 1372-1379
    • Lovinger, D.M.1    White, G.2    Weight, F.F.3
  • 26
    • 0027304782 scopus 로고
    • Diversity of glutamate receptor subunit mRNA expression within live hippocampal CA1 neurons
    • [26] Mackler, S.A. and Eberwine, J.H., Diversity of glutamate receptor subunit mRNA expression within live hippocampal CA1 neurons, Mol. Pharmacol., 44 (1993) 308-315.
    • (1993) Mol. Pharmacol. , vol.44 , pp. 308-315
    • Mackler, S.A.1    Eberwine, J.H.2
  • 27
    • 0028081936 scopus 로고
    • Differential ethanol sensitivity of recombinant N-methyl-D-aspartate receptor subunits
    • [27] Masood, K., Wu, C., Brauneis, U. and Weight, F., Differential ethanol sensitivity of recombinant N-methyl-D-aspartate receptor subunits, Mol. Pharmacol., 45 (1994) 324-329.
    • (1994) Mol. Pharmacol. , vol.45 , pp. 324-329
    • Masood, K.1    Wu, C.2    Brauneis, U.3    Weight, F.4
  • 28
    • 0010548403 scopus 로고
    • Two classes of N-methyl-D-aspartate recognition sites: Differential distribution and differential regulation by glycine
    • [28] Monaghan, D.T., Olverman, H.J., Nguyen, L., Watkins, J.C. and Cotman, C.W., Two classes of N-methyl-D-aspartate recognition sites: differential distribution and differential regulation by glycine, Proc. Natl. Acad. Sci. USA, 85 (1988) 9836-9840.
    • (1988) Proc. Natl. Acad. Sci. USA , vol.85 , pp. 9836-9840
    • Monaghan, D.T.1    Olverman, H.J.2    Nguyen, L.3    Watkins, J.C.4    Cotman, C.W.5
  • 29
    • 0025947757 scopus 로고
    • Ethanol and magnesium ions inhibit N-methyl-D-aspartate mediated synaptic potentials in an interactive manner
    • [29] Morrisett, R.A., Martin, D., Oetting, T.A., Lewis, D.V., Wilson, W.A. and Swartzwelder, H.S., Ethanol and magnesium ions inhibit N-methyl-D-aspartate mediated synaptic potentials in an interactive manner, Neuropharmacology, 30 (1991) 1173-1178.
    • (1991) Neuropharmacology , vol.30 , pp. 1173-1178
    • Morrisett, R.A.1    Martin, D.2    Oetting, T.A.3    Lewis, D.V.4    Wilson, W.A.5    Swartzwelder, H.S.6
  • 30
    • 0027398931 scopus 로고
    • Attenuation of hippocampal long-term potentiation by ethanol: A patch-clamp analysis of glutamatergic and GABAergic mechanisms
    • [30] Morrisett, R.A. and Swartzwelder, H.S., Attenuation of hippocampal long-term potentiation by ethanol: a patch-clamp analysis of glutamatergic and GABAergic mechanisms, J. Neurosci., 13 (1993) 2264-2272.
    • (1993) J. Neurosci. , vol.13 , pp. 2264-2272
    • Morrisett, R.A.1    Swartzwelder, H.S.2
  • 31
    • 0026779363 scopus 로고
    • Alternative splicing generates functionally distinct N-methyl-D-aspartate receptors
    • [31] Nakanishi, N., Axel, R. and Shneider, N.A., Alternative splicing generates functionally distinct N-methyl-D-aspartate receptors, Proc. Natl. Acad. Sci. USA, 89 (1992) 8552-8556.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 8552-8556
    • Nakanishi, N.1    Axel, R.2    Shneider, N.A.3
  • 32
    • 0027526363 scopus 로고
    • Whole cell and single channel analysis of the kinetics of glycine-sensitive N-methyl-D-aspartate receptor desensitization
    • [32] Parsons, C.G., Zong, X. and Lux, H.D., Whole cell and single channel analysis of the kinetics of glycine-sensitive N-methyl-D-aspartate receptor desensitization, Br. J. Pharmacol., 109 (1993) 213-221.
    • (1993) Br. J. Pharmacol. , vol.109 , pp. 213-221
    • Parsons, C.G.1    Zong, X.2    Lux, H.D.3
  • 33
    • 0026501791 scopus 로고
    • Ethanol inhibition of N-methyl-D-aspartate-activated ion current in rat hippocampal neurons is not competitive with glycine
    • [33] Peoples, R.W. and Weight, F.F., Ethanol inhibition of N-methyl-D-aspartate-activated ion current in rat hippocampal neurons is not competitive with glycine, Brain Res., 571 (1992) 342-344.
    • (1992) Brain Res. , vol.571 , pp. 342-344
    • Peoples, R.W.1    Weight, F.F.2
  • 34
    • 0028920637 scopus 로고
    • Cutoff in potency implicates alcohol inhibition of N-methyl-D-aspartate receptors in alcohol intoxication
    • [34] Peoples, R.W. and Weight, F.F., Cutoff in potency implicates alcohol inhibition of N-methyl-D-aspartate receptors in alcohol intoxication, Proc. Natl. Acad. Sci. USA, 92 (1995) 2825-2829.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 2825-2829
    • Peoples, R.W.1    Weight, F.F.2
  • 35
    • 0025684618 scopus 로고
    • Glycine site-directed agonists reverse the actions of ethanol at the N-methyl-D-aspartate receptor
    • [35] Rabe, C.S. and Tabakoff, B., Glycine site-directed agonists reverse the actions of ethanol at the N-methyl-D-aspartate receptor, Mol. Pharmacol., 38 (1990) 753-757.
    • (1990) Mol. Pharmacol. , vol.38 , pp. 753-757
    • Rabe, C.S.1    Tabakoff, B.2
  • 36
    • 0029871926 scopus 로고    scopus 로고
    • N-methyl-D-aspartate-stimulated increases in intracellular calcium exhibit brain regional differences in sensitivity to inhibition by ethanol
    • [36] Randoll, L.A., Wilson, W.R., Weaver, M.S., Spuhler-Phillips, K. and Leslie, S.W., N-methyl-D-aspartate-stimulated increases in intracellular calcium exhibit brain regional differences in sensitivity to inhibition by ethanol, Alcohol. Clin. Exp. Res., 20 (1996) 197-200.
    • (1996) Alcohol. Clin. Exp. Res. , vol.20 , pp. 197-200
    • Randoll, L.A.1    Wilson, W.R.2    Weaver, M.S.3    Spuhler-Phillips, K.4    Leslie, S.W.5
  • 37
    • 0019639322 scopus 로고
    • Nerve outgrowth, synaptogenesis and bioelectric activity in fetal rat cerebral cortex cultured in serum-free, chemically defined medium
    • [37] Romijn, H., Habets, A.M.M.C., Mud, M.T. and Wolters, P.S., Nerve outgrowth, synaptogenesis and bioelectric activity in fetal rat cerebral cortex cultured in serum-free, chemically defined medium, Dev. Brain Res., 2 (1982) 583-589.
    • (1982) Dev. Brain Res. , vol.2 , pp. 583-589
    • Romijn, H.1    Habets, A.M.M.C.2    Mud, M.T.3    Wolters, P.S.4
  • 38
    • 0027258451 scopus 로고
    • Calcium-induced actin depolymerization reduces NMDA channel activity
    • [38] Rosenmund, C. and Westbrook, G.L., Calcium-induced actin depolymerization reduces NMDA channel activity, Neuron, 10 (1993) 805-814.
    • (1993) Neuron , vol.10 , pp. 805-814
    • Rosenmund, C.1    Westbrook, G.L.2
  • 39
    • 0027510699 scopus 로고
    • Inhibition of NMDA-evoked electrophysiological activity by ethanol in selected brain regions: Evidence for ethanol-sensitive and ethanol-insensitive NMDA-evoked responses
    • [39] Simson, P.E., Criswell, H.E. and Breese, G.R., Inhibition of NMDA-evoked electrophysiological activity by ethanol in selected brain regions: evidence for ethanol-sensitive and ethanol-insensitive NMDA-evoked responses, Brain Res., 607 (1993) 9-16.
    • (1993) Brain Res. , vol.607 , pp. 9-16
    • Simson, P.E.1    Criswell, H.E.2    Breese, G.R.3
  • 40
    • 0027405992 scopus 로고
    • Radioligand binding to the N-methyl-D-aspartate receptor/ionophore complex: Alterations by ethanol in vitro and by chronic in vivo ethanol ingestion
    • [40] Snell, L.D., Tabakoff, B. and Hoffman, P.L., Radioligand binding to the N-methyl-D-aspartate receptor/ionophore complex: Alterations by ethanol in vitro and by chronic in vivo ethanol ingestion, Brain Res., 602 (1993) 91-98.
    • (1993) Brain Res. , vol.602 , pp. 91-98
    • Snell, L.D.1    Tabakoff, B.2    Hoffman, P.L.3
  • 41
    • 0026398674 scopus 로고
    • Alcohol inhibition of NMDA channel function
    • [41] Weight, F.F., Lovinger, D.M. and White, G., Alcohol inhibition of NMDA channel function. Alcohol Alcoholism, Suppl. 1 (1991) 163-169.
    • (1991) Alcohol Alcoholism , Issue.SUPPL. 1 , pp. 163-169
    • Weight, F.F.1    Lovinger, D.M.2    White, G.3
  • 42
    • 0002584373 scopus 로고
    • Neurotransmitter-gated ion channels as molecular sites of alcohol action
    • C. Alling, I. Diamond, S.W. Leslie, G.Y. Sun and W.G. Wood (Eds.), Plenum Press, New York
    • [42] Weight, F.F., Peoples, R.W., Wright, J.M., et al. Neurotransmitter-gated ion channels as molecular sites of alcohol action. In C. Alling, I. Diamond, S.W. Leslie, G.Y. Sun and W.G. Wood (Eds.), Alcohol, Cell Membranes, and Signal Transduction in Brain, Plenum Press, New York, 1993, pp. 107-122.
    • (1993) Alcohol, Cell Membranes, and Signal Transduction in Brain , pp. 107-122
    • Weight, F.F.1    Peoples, R.W.2    Wright, J.M.3
  • 43
    • 0025096750 scopus 로고
    • Ethanol inhibits NMA-activated current but does not alter GABA-activated current in an isolated adult mammalian neuron
    • [43] White, G., Lovinger, D.M. and Weight, F.F., Ethanol inhibits NMA-activated current but does not alter GABA-activated current in an isolated adult mammalian neuron, Brain Res., 507 (1990) 332-336.
    • (1990) Brain Res. , vol.507 , pp. 332-336
    • White, G.1    Lovinger, D.M.2    Weight, F.F.3
  • 44
    • 0028047489 scopus 로고
    • A comparison of the effects of ethanol and the competitive glycine antagonist 7-chlorokynurenic acid on N-methyl-D-aspartate acid-induced neurotransmitter release from rat hippocampal slices
    • [44] Woodward, J.J., A comparison of the effects of ethanol and the competitive glycine antagonist 7-chlorokynurenic acid on N-methyl-D-aspartate acid-induced neurotransmitter release from rat hippocampal slices, J. Neurochem., 62 (1994) 987-991.
    • (1994) J. Neurochem. , vol.62 , pp. 987-991
    • Woodward, J.J.1
  • 45
    • 0025019986 scopus 로고
    • Ethanol inhibition of N-methyl-D-aspartate-stimulated endogenous dopamine release from rat striatal slices: Reversal by glycine
    • [45] Woodward, J.J. and Gonzales, R.A., Ethanol inhibition of N-methyl-D-aspartate-stimulated endogenous dopamine release from rat striatal slices: reversal by glycine, J. Neurochem., 54 (1990) 712-715.
    • (1990) J. Neurochem. , vol.54 , pp. 712-715
    • Woodward, J.J.1    Gonzales, R.A.2
  • 46
    • 4243507186 scopus 로고    scopus 로고
    • Tissue dissociation methods alter the effects of low concentraions of ethanol on NMDA-activated whole-cell currents
    • [46] Wright, J.M., Tissue dissociation methods alter the effects of low concentraions of ethanol on NMDA-activated whole-cell currents, Alcohol. Clin. Exp. Res., 20 (1996) 9A.
    • (1996) Alcohol. Clin. Exp. Res. , vol.20
    • Wright, J.M.1
  • 47
    • 0025744464 scopus 로고
    • Multiple effects of tetraethylammonium on N-methyl-D-aspartate receptor-channels in mouse brain neurons in cell culture
    • [47] Wright, J.M., Kline, P.A. and Nowak, L.M., Multiple effects of tetraethylammonium on N-methyl-D-aspartate receptor-channels in mouse brain neurons in cell culture, J. Physiol. (Lond.), 439 (1991) 579-604.
    • (1991) J. Physiol. (Lond.) , vol.439 , pp. 579-604
    • Wright, J.M.1    Kline, P.A.2    Nowak, L.M.3
  • 48
    • 0011930140 scopus 로고
    • Ethanol decreases both mean open time and frequency of opening of NMDA receptor-channels
    • [48] Wright, J.M., Peoples, R.W. and Weight, F.F., Ethanol decreases both mean open time and frequency of opening of NMDA receptor-channels, Soc. Neurosci. Abstr., 19 (1993) 716.
    • (1993) Soc. Neurosci. Abstr. , vol.19 , pp. 716
    • Wright, J.M.1    Peoples, R.W.2    Weight, F.F.3
  • 49
    • 0011930141 scopus 로고
    • Effects of ethanol on NMDA receptor-channels in single channel recordings
    • [49] Wright, J.M. and Weight, F.F., Effects of ethanol on NMDA receptor-channels in single channel recordings, Soc. Neurosci. Abstr., 18 (1992) 257.
    • (1992) Soc. Neurosci. Abstr. , vol.18 , pp. 257
    • Wright, J.M.1    Weight, F.F.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.