Effects of amino acid substitutions in transmembrane domains of the NR1 subunit on the ethanol inhibition recombinant N-methyl-D-aspartate receptors

Alcoholism: Clinical and Experimental Research

Volumn 30, Issue 3, 2006, Pages 523-530

  Thetford Smothers, C ^a   Woodward, John J ^a,b  

^a MUSC Center for Drug and Alcohol Programs   (United States)

^b MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

Author keywords

Ethanol; Mutagenesis; NMDA Receptor; Transmembrane Domain

Indexed keywords

ALANINE; ALCOHOL; GLYCINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 1; PHENYLALANINE; PROTEIN SUBUNIT; TRYPTOPHAN;

AMINO ACID SUBSTITUTION; ARTICLE; CELL STRAIN HEK293; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CORRELATION ANALYSIS; ELECTROPHYSIOLOGY; GENE MUTATION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN STRUCTURE; SENSITIVITY ANALYSIS; SEQUENCE HOMOLOGY; SITE DIRECTED MUTAGENESIS; STATISTICAL SIGNIFICANCE; VOLTAGE CLAMP; WHOLE CELL;

AMINO ACID SUBSTITUTION; CELL LINE; CENTRAL NERVOUS SYSTEM DEPRESSANTS; DNA, COMPLEMENTARY; ELECTROPHYSIOLOGY; ETHANOL; EXCITATORY AMINO ACID ANTAGONISTS; HUMANS; MEMBRANE POTENTIALS; MUTAGENESIS, SITE-DIRECTED; PATCH-CLAMP TECHNIQUES; RECEPTORS, N-METHYL-D-ASPARTATE; RECOMBINANT PROTEINS;

EID: 33644777700     PISSN: 01456008     EISSN: 15300277     Source Type: Journal    
DOI: 10.1111/j.1530-0277.2006.00058.x     Document Type: Article

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