Ca2+-dependent inactivation of NMDA receptors: Fast kinetics and high Ca2+ sensitivity in rat dorsal horn neurons

Journal of Physiology

Volumn 495, Issue 2, 1996, Pages 449-463

  Kyrozis, Andreas ^a   Albuquerque, Cristóvão ^a   Gu, Jianguo ^a   MacDermott, Amy B ^a  

^a Columbia University ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CAFFEINE; CALCIUM CHANNEL; CALCIUM ION; GLYCINE; N METHYL DEXTRO ASPARTIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; RYANODINE;

ANIMAL CELL; ARTICLE; CALCIUM CELL LEVEL; CALCIUM CURRENT; CALCIUM TRANSPORT; CONTROLLED STUDY; DOSE RESPONSE; EMBRYO; EVOKED RESPONSE; KINETICS; NERVE CELL CULTURE; NERVOUS SYSTEM DEVELOPMENT; NONHUMAN; PATCH CLAMP; PRIORITY JOURNAL; RAT; RECEPTOR AFFINITY; SECOND MESSENGER; SPINAL CORD DORSAL HORN; VOLTAGE CLAMP;

EID: 0029742334     PISSN: 00223751     EISSN: None     Source Type: Journal    
DOI: 10.1113/jphysiol.1996.sp021606     Document Type: Article

References (41)

1. ARTOLA, A. & SINGER, W. (1993). Long-term depression of excitatory synaptic transmission and its relationship to long-term potentiation. Trends in Neurosciences 16, 480-487.
2. ASCHER, P. & NOWAK, L. (1988). The role of divalent cations in the N-methyl-D-aspartate response of mouse central neurones in culture. Journal of Physiology 399, 247-266.
3. BENVENISTE, M., CLEMENTS, J., VYKLICKÝ, L. JR & MAYER, M. L. (1990). A kinetic analysis of the modulation of the N-methyl-D-aspartic acid receptors by glycine in mouse cultured hippocampal neurones. Journal of Physiology 428, 333-357.
4. BLISS, T. V. P. & COLLINGRIDGE, G. L. (1993). A synaptic model of memory: long-term potentiation in the hippocampus. Nature 361, 31-39.
5. CARMIGNIOTO, G. & VICINI, S. (1992). Activity-dependent decrease in NMDA receptor responses during development of the visual cortex. Science 258, 1007-1011.
6. CLARK, G. D., CLIFFORD, D. B. & ZORUMSKI, C. F. (1990). The effect of agonist concentration, membrane voltage and calcium on N-methyl-D-aspartate receptor desensitization. Neuroscience 39, 787-797.
7. CLEMENTS, J. D., LESTER, R. A. J., TONG, G., JAHR, C. E. & WESTBROOK, G. L. (1992). The time course of glutamate in the synaptic cleft. Science 258, 1498-1501.
8. COAN, E. J., IRVING., A. J. & COLLINGRIDGE, G. L. (1989). Low-frequency activation of the NMDA receptor system can prevent the induction of LTP. Neuroscience Letters 105, 205-210.
9. 2+ indicators with greatly improved fluorescence properties. Journal of Biological Chemistry 260, 3440-3450.
10. 2+-penneable AMPA receptors. Nature 381, 793-796.
11. 2+ in neurons. Neuroscience 46, 251-273.
12. HESTRIN, S. (1992). Developmental regulation of NMDA receptor-mediated synaptic currents at a central synapse. Nature 357, 686-689.
13. HESTRIN, S., SAH, P., PANKAJ, S. & NICOLL, R. A. (1990). Mechanisms generating the time course of dual component excitatory synaptic currents recorded in hippocampal slices. Neuron 5, 247-253.
14. HORN, R. & MARTY, A. (1988). Muscarinic activation of ionic currents measured by a new whole-cell recording method. Journal of General Physiology 92, 145-159.
15. JAHR, C. E. & STEVENS, C. F. (1993). Calcium permeability of the N-methyl-D-aspartate receptor channel in hippocampal neurons in culture. Proceedings of the National Acadamy of Science 90, 11573-11577.
16. KYROZIS, A., GOLDSTEIN, P. A., HEATH, M. J. S. & MACDERMOTT, A. B. (1995). Calcium entry through a subpopulation of AMPA receptors desensitized neighbouring NMDA receptors in rat dorsal horn neurons. Journal of Physiology 485, 373-381.
17. KYROZIS, A. & REICHLING, D. B. (1995). Perforated patch recording with gramicidin avoids artifactual changes in intracellular chloride concentration. Journal of Neuroscience Methods 57, 27-35.
18. LEGENDRE, P., ROSENMUND, C. & WESTBROOK, G. L. (1993). Inactivation of NMDA channels in cultured hippocampal neurons by intracellular calcium. Journal of Neuroscience 13, 674-684.
19. MCMAHON, S. B., LEWIN, G. R. & WALL, P. D. (1993). Central hyper-excitability triggered by noxious inputs. Current Opinion in Neurobiology 3, 602-610.
20. MARKRAM, H. & SEGAL, M. (1991). Calcimycin potentiates responses of rat hippocampal neurons to N-methyl-D-aspartate. Brain Research 540, 322-324.
21. MARKRAM, H. & SEGAL, M. (1992). The inositol 1,4,5-trisphosphate pathway mediates cholinergic potentiation of rat hippocampal neuronal responses to NMDA. Journal of Physiology 447, 513-533.
22. MAYER, M. L., MACDERMOTT, A, B., WESTBROOK, G. L., SMITH, S. J. & BARKER, J. L. (1987). Calcium transients recorded from mouse spinal cord neurons under voltage-clamp. Journal of Neuroscience 7, 3230-3244.
23. MAYER, M. L., VYKLICKÝ, L. JR & CLEMENTS, J. (1989). Regulation of NMDA receptor desensitization in mouse hippocampal neurons by glycine. Nature 338, 425-427.
24. MAYER, M. L. & WESTBROOK, G. L. (1985). The action of N-methyl-D-aspartic acid on mouse spinal neurones in culture. Journal of Physiology 361, 65-90.
25. 2+ in hippocampal neurons. Journal of Neurophysiology 72, 456-465.
26. MURASE, K., RYU, P. D. & RANDIC, M. (1989). Excitatory and inhibitory amino acids and peptide-induced responses in acutely isolated rat spinal doral horn neurons. Neuroscience Letters 103, 56-63.
27. NEHER, E. & AUGUSTINE, G. J. (1992). Calcium gradients and buffers in bovine chromaffin cells. Journal of Physiology 450, 273-301.
28. O'DELL, T. J., HAWKINS, R. D., KANDEL, E. R. & ARANCIO, O. (1991). Tests of the roles of two diffusible substances in long-term potentiation: evidence for nitric oxide as a possible early retrograde messenger. Proceedings of the National Academy of Sciences of the USA 88, 11285-11289.
29. RAE, J., COOPER, K., GATES, P. & WATSKY, M. (1991). Low access resistance perforated patch recordings using amphotericin B. Journal of Neuroscience Methods 37, 15-26.
30. RALL, T. W. (1982). Evolution of the mechanism of action of methylxanthines: from calcium mobilizers to antagonists of adenosine receptors. Pharmacologist 24, 277-287.
31. REGEHR, W. G. & TANK, D. W. (1992). Calcium concentration dynamics produced by synaptic activation of CA1 hippocampal pyramidal cells. Journal of Neuroscience 12, 4202-4223.
32. REICHLING, D. B. & MACDERMOTT, A. B. (1996). NMDA receptor-mediated calcium entry in the absence of AMPA receptor activation in rat dorsal horn neurons. Neuroscience Letters 203, 1-4.
33. ROSENMUND, C., FELTZ, A. & WESTBROOK, G. L. (1995). Calcium-dependent inactivation of synaptic NMDA receptors in hippocampal neurons. Journal of Neurophysiology 73, 427-430.
34. ROSENMUND, C. & WESTBROOK, G. L. (1993). Calcium-induced actin depolymerization reduces NMDA channel activity. Neuron 10, 805-814.
35. SALA, F. & HERNANDEZ-CRUZ, A. (1990). Calcium diffusion modeling in a spherical neuron. Relevance of buffering properties. Biophysical Journal 57, 313-324.
36. SATHER, W., JOHNSON, J. W., HENDERSON, G. & ASCHER, P. (1990). Glycine-insensitive desensitization of NMDA responses in cultured mouse embryonic neurons. Neuron 4, 725-731.
37. SCHIEREN, I. & MACDERMOTT, A. B. (1992). Isolation and characterization of transfected cell lines expressing neurotransmitter receptors using a calcium dye and flow cytometry. In Cell Lines for Neurobiology. A Practical Approach, ed. WOOD, J., pp. 161-179. Oxford University Press, New York.
38. SMITH, S. J., OSSES, L. R. & AUGUSTINE, G. J. (1988). Fura-2 imaging of localized calcium accumulation within squid 'giant' presynaptic terminals. In Calcium and Ion Channel Modulation, ed. GRINNEL, A. D., ARMSTRONG, D. & JACKSON, M. B., pp. 147-155. Plenum Press, New York.
39. VYKLICKV́, L. JR (1993). Calcium-mediated modulation of N-methyl-D-aspartate (NMDA) responses in cultured rat hippocampal neurones. Journal of Physiology 470, 575-600.
40. VYKLICKÝ, L. JR, BENVENISTE, M. & MAYER, M. L. (1990). Modulation of N-methyl-D-aspartic acid receptor desensitization by glycine in mouse cultured hippocampal neurones. Journal of Physiology 428, 313-331.
41. ZILBERTER, Y., UTESHEV, V., SOKOLOVA, S. & KHODOROV, B. (1991). Desensitization of N-methyl-D-aspartate receptors dissociated from adult rat hippocampus. Molecular Pharmacology 40, 337-341.