메뉴 건너뛰기




Volumn 45, Issue 4, 2011, Pages 373-380

Effects of ethanol on phosphorylation site mutants of recombinant N-methyl-d-aspartate receptors

Author keywords

Alcohol; Electrophysiology; Mutagenesis; Phosphorylation; PKA; PKC

Indexed keywords

ALANINE; ALCOHOL; ASPARTIC ACID; CYCLIC AMP DEPENDENT PROTEIN KINASE; GLUTAMIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 1; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 1A; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 1B; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 2A; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 2B; PROTEIN KINASE C; RECOMBINANT PROTEIN; SERINE; THREONINE; UNCLASSIFIED DRUG;

EID: 79955949857     PISSN: 07418329     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.alcohol.2010.08.015     Document Type: Article
Times cited : (15)

References (38)
  • 1
    • 0034685878 scopus 로고    scopus 로고
    • Reduced ethanol inhibition of N-methyl-D-aspartate receptors by deletion of the NR1 C0 domain or overexpression of alpha-actinin-2 proteins
    • Anders D.L., Blevins T., Smothers C.T., Woodward J.J. Reduced ethanol inhibition of N-methyl-D-aspartate receptors by deletion of the NR1 C0 domain or overexpression of alpha-actinin-2 proteins. J. Biol. Chem. 2000, 275:15019-15024.
    • (2000) J. Biol. Chem. , vol.275 , pp. 15019-15024
    • Anders, D.L.1    Blevins, T.2    Smothers, C.T.3    Woodward, J.J.4
  • 2
    • 0033027998 scopus 로고    scopus 로고
    • Effects of c-Src tyrosine kinase on ethanol sensitivity of recombinant NMDA receptors expressed in HEK 293 cells
    • Anders D.L., Blevins T., Sutton G., Chandler L.J., Woodward J.J. Effects of c-Src tyrosine kinase on ethanol sensitivity of recombinant NMDA receptors expressed in HEK 293 cells. Alcohol. Clin. Exp. Res. 1999, 23:357-362.
    • (1999) Alcohol. Clin. Exp. Res. , vol.23 , pp. 357-362
    • Anders, D.L.1    Blevins, T.2    Sutton, G.3    Chandler, L.J.4    Woodward, J.J.5
  • 3
    • 0033034784 scopus 로고    scopus 로고
    • Fyn tyrosine kinase reduces the ethanol inhibition of recombinant NR1/NR2A but not NR1/NR2B NMDA receptors expressed in HEK 293 cells
    • Anders D.L., Blevins T., Sutton G., Swope S., Chandler L.J., Woodward J.J. Fyn tyrosine kinase reduces the ethanol inhibition of recombinant NR1/NR2A but not NR1/NR2B NMDA receptors expressed in HEK 293 cells. J. Neurochem. 1999, 72:1389-1393.
    • (1999) J. Neurochem. , vol.72 , pp. 1389-1393
    • Anders, D.L.1    Blevins, T.2    Sutton, G.3    Swope, S.4    Chandler, L.J.5    Woodward, J.J.6
  • 5
    • 0028157126 scopus 로고
    • Expression of NMDAR1-1a (N598Q)/NMDAR2A receptors results in decreased cell mortality
    • Cik M., Chazot P.L., Stephenson F.A. Expression of NMDAR1-1a (N598Q)/NMDAR2A receptors results in decreased cell mortality. Eur. J. Pharmacol. 1994, 266:R1-R3.
    • (1994) Eur. J. Pharmacol. , vol.266
    • Cik, M.1    Chazot, P.L.2    Stephenson, F.A.3
  • 6
    • 0033637782 scopus 로고    scopus 로고
    • Effects of volatile solvents on recombinant N-methyl-D-aspartate receptors expressed in Xenopus oocytes
    • Cruz S.L., Balster R.L., Woodward J.J. Effects of volatile solvents on recombinant N-methyl-D-aspartate receptors expressed in Xenopus oocytes. Br. J. Pharmacol. 2000, 131:1303-1308.
    • (2000) Br. J. Pharmacol. , vol.131 , pp. 1303-1308
    • Cruz, S.L.1    Balster, R.L.2    Woodward, J.J.3
  • 8
    • 0029147928 scopus 로고
    • Regulated subcellular distribution of the NR1 subunit of the NMDA receptor
    • Ehlers M.D., Tingley W.G., Huganir R.L. Regulated subcellular distribution of the NR1 subunit of the NMDA receptor. Science 1995, 269:1734-1737.
    • (1995) Science , vol.269 , pp. 1734-1737
    • Ehlers, M.D.1    Tingley, W.G.2    Huganir, R.L.3
  • 9
    • 1442275393 scopus 로고    scopus 로고
    • Sites in the fourth membrane-associated domain regulate alcohol sensitivity of the NMDA receptor
    • Honse Y., Ren H., Lipsky R.H., Peoples R.W. Sites in the fourth membrane-associated domain regulate alcohol sensitivity of the NMDA receptor. Neuropharmacology 2004, 46:647-654.
    • (2004) Neuropharmacology , vol.46 , pp. 647-654
    • Honse, Y.1    Ren, H.2    Lipsky, R.H.3    Peoples, R.W.4
  • 10
    • 44349168838 scopus 로고    scopus 로고
    • Enhanced ethanol inhibition of recombinant N-methyl-D-aspartate receptors by magnesium: role of NR3A subunits
    • Jin C., Smothers C.T., Woodward J.J. Enhanced ethanol inhibition of recombinant N-methyl-D-aspartate receptors by magnesium: role of NR3A subunits. Alcohol. Clin. Exp. Res. 2008, 32:1059-1066.
    • (2008) Alcohol. Clin. Exp. Res. , vol.32 , pp. 1059-1066
    • Jin, C.1    Smothers, C.T.2    Woodward, J.J.3
  • 11
    • 33645343292 scopus 로고    scopus 로고
    • Effects of 8 different NR1 splice variants on the ethanol inhibition of recombinant NMDA receptors
    • Jin C., Woodward J.J. Effects of 8 different NR1 splice variants on the ethanol inhibition of recombinant NMDA receptors. Alcohol. Clin. Exp. Res. 2006, 30:673-679.
    • (2006) Alcohol. Clin. Exp. Res. , vol.30 , pp. 673-679
    • Jin, C.1    Woodward, J.J.2
  • 12
    • 0035040079 scopus 로고    scopus 로고
    • Evidence for direct protein kinase-C mediated modulation of N-methyl-D-aspartate receptor current
    • Liao G.Y., Wagner D.A., Hsu M.H., Leonard J.P. Evidence for direct protein kinase-C mediated modulation of N-methyl-D-aspartate receptor current. Mol. Pharmacol. 2001, 59:960-964.
    • (2001) Mol. Pharmacol. , vol.59 , pp. 960-964
    • Liao, G.Y.1    Wagner, D.A.2    Hsu, M.H.3    Leonard, J.P.4
  • 13
    • 29444433657 scopus 로고    scopus 로고
    • CaM kinase II phosphorylation of slo Thr107 regulates activity and ethanol responses of BK channels
    • Liu J., Asuncion-Chin M., Liu P., Dopico A.M. CaM kinase II phosphorylation of slo Thr107 regulates activity and ethanol responses of BK channels. Nat. Neurosci. 2006, 9:41-49.
    • (2006) Nat. Neurosci. , vol.9 , pp. 41-49
    • Liu, J.1    Asuncion-Chin, M.2    Liu, P.3    Dopico, A.M.4
  • 14
    • 2642526203 scopus 로고    scopus 로고
    • Distinct expression of phosphorylated N-methyl-D-aspartate receptor NR1 subunits by projection neurons and interneurons in the striatum of normal and amphetamine-treated rats
    • Liu Z., Mao L., Parelkar N.K., Tang Q., Samdani S., Wang J.Q. Distinct expression of phosphorylated N-methyl-D-aspartate receptor NR1 subunits by projection neurons and interneurons in the striatum of normal and amphetamine-treated rats. J. Comp. Neurol. 2004, 474:393-406.
    • (2004) J. Comp. Neurol. , vol.474 , pp. 393-406
    • Liu, Z.1    Mao, L.2    Parelkar, N.K.3    Tang, Q.4    Samdani, S.5    Wang, J.Q.6
  • 15
    • 0024535962 scopus 로고
    • Ethanol inhibits NMDA-activated ion current in hippocampal neurons
    • Lovinger D.M., White G., Weight F.F. Ethanol inhibits NMDA-activated ion current in hippocampal neurons. Science 1989, 243:1721-1724.
    • (1989) Science , vol.243 , pp. 1721-1724
    • Lovinger, D.M.1    White, G.2    Weight, F.F.3
  • 16
    • 0033366541 scopus 로고    scopus 로고
    • G-protein-coupled receptors act via protein kinase C and Src to regulate NMDA receptors
    • Lu W.Y., Xiong Z.G., Lei S., Orser B.A., Dudek E., Browning M.D., et al. G-protein-coupled receptors act via protein kinase C and Src to regulate NMDA receptors. Nat. Neurosci. 1999, 2:331-338.
    • (1999) Nat. Neurosci. , vol.2 , pp. 331-338
    • Lu, W.Y.1    Xiong, Z.G.2    Lei, S.3    Orser, B.A.4    Dudek, E.5    Browning, M.D.6
  • 17
    • 5344241223 scopus 로고    scopus 로고
    • LTP and LTD: an embarrassment of riches
    • Malenka R.C., Bear M.F. LTP and LTD: an embarrassment of riches. Neuron 2004, 44:5-21.
    • (2004) Neuron , vol.44 , pp. 5-21
    • Malenka, R.C.1    Bear, M.F.2
  • 19
    • 0028081936 scopus 로고
    • Differential ethanol sensitivity of recombinant N-methyl-D-aspartate receptor subunits
    • Masood K., Wu C., Brauneis U., Weight F.F. Differential ethanol sensitivity of recombinant N-methyl-D-aspartate receptor subunits. Mol. Pharmacol. 1994, 45:324-329.
    • (1994) Mol. Pharmacol. , vol.45 , pp. 324-329
    • Masood, K.1    Wu, C.2    Brauneis, U.3    Weight, F.F.4
  • 20
    • 0031848644 scopus 로고    scopus 로고
    • Intracellular calcium enhances the ethanol sensitivity of NMDA receptors through an interaction with the C0 domain of the NR1 subunit
    • Mirshahi T., Anders D.L., Ronald K.M., Woodward J.J. Intracellular calcium enhances the ethanol sensitivity of NMDA receptors through an interaction with the C0 domain of the NR1 subunit. J. Neurochem. 1998, 71:1095-1107.
    • (1998) J. Neurochem. , vol.71 , pp. 1095-1107
    • Mirshahi, T.1    Anders, D.L.2    Ronald, K.M.3    Woodward, J.J.4
  • 21
    • 0028930865 scopus 로고
    • Ethanol sensitivity of heteromeric NMDA receptors: effects of subunit assembly, glycine and NMDAR1 Mg2+-insensitive mutants
    • Mirshahi T., Woodward J.J. Ethanol sensitivity of heteromeric NMDA receptors: effects of subunit assembly, glycine and NMDAR1 Mg2+-insensitive mutants. Neuropharmacology 1995, 34:347-355.
    • (1995) Neuropharmacology , vol.34 , pp. 347-355
    • Mirshahi, T.1    Woodward, J.J.2
  • 23
    • 0026501791 scopus 로고
    • Ethanol inhibition of N-methyl-D-aspartate-activated ion current in rat hippocampal neurons is not competitive with glycine
    • Peoples R.W., Weight F.F. Ethanol inhibition of N-methyl-D-aspartate-activated ion current in rat hippocampal neurons is not competitive with glycine. Brain Res. 1992, 571:342-344.
    • (1992) Brain Res. , vol.571 , pp. 342-344
    • Peoples, R.W.1    Weight, F.F.2
  • 24
    • 34249678451 scopus 로고    scopus 로고
    • Phosphorylation of threonine residue 276 is required for acute regulation of serotonin transporter by cyclic GMP
    • Ramamoorthy S., Samuvel D.J., Buck E.R., Rudnick G., Jayanthi L.D. Phosphorylation of threonine residue 276 is required for acute regulation of serotonin transporter by cyclic GMP. J. Biol. Chem. 2007, 282:11639-11647.
    • (2007) J. Biol. Chem. , vol.282 , pp. 11639-11647
    • Ramamoorthy, S.1    Samuvel, D.J.2    Buck, E.R.3    Rudnick, G.4    Jayanthi, L.D.5
  • 25
    • 1442267292 scopus 로고    scopus 로고
    • A site of alcohol action in the fourth membrane-associated domain of the N-methyl-D-aspartate receptor
    • Ren H., Honse Y., Peoples R.W. A site of alcohol action in the fourth membrane-associated domain of the N-methyl-D-aspartate receptor. J. Biol. Chem. 2003, 278:48815-48820.
    • (2003) J. Biol. Chem. , vol.278 , pp. 48815-48820
    • Ren, H.1    Honse, Y.2    Peoples, R.W.3
  • 26
    • 0035976931 scopus 로고    scopus 로고
    • Ethanol inhibition of N-methyl-D-aspartate receptors is reduced by site-directed mutagenesis of a transmembrane domain phenylalanine residue
    • Ronald K.M., Mirshahi T., Woodward J.J. Ethanol inhibition of N-methyl-D-aspartate receptors is reduced by site-directed mutagenesis of a transmembrane domain phenylalanine residue. J. Biol. Chem. 2001, 276:44729-44735.
    • (2001) J. Biol. Chem. , vol.276 , pp. 44729-44735
    • Ronald, K.M.1    Mirshahi, T.2    Woodward, J.J.3
  • 27
    • 20544432404 scopus 로고    scopus 로고
    • Serines 890 and 896 of the NMDA receptor subunit NR1 are differentially phosphorylated by protein kinase C isoforms
    • Sanchez-Perez A.M., Felipo V. Serines 890 and 896 of the NMDA receptor subunit NR1 are differentially phosphorylated by protein kinase C isoforms. Neurochem. Int. 2005, 47:84-91.
    • (2005) Neurochem. Int. , vol.47 , pp. 84-91
    • Sanchez-Perez, A.M.1    Felipo, V.2
  • 28
    • 1542614144 scopus 로고    scopus 로고
    • Coordinated PKA and PKC phosphorylation suppresses RXR-mediated ER retention and regulates the surface delivery of NMDA receptors
    • Scott D.B., Blanpied T.A., Ehlers M.D. Coordinated PKA and PKC phosphorylation suppresses RXR-mediated ER retention and regulates the surface delivery of NMDA receptors. Neuropharmacology 2003, 45:755-767.
    • (2003) Neuropharmacology , vol.45 , pp. 755-767
    • Scott, D.B.1    Blanpied, T.A.2    Ehlers, M.D.3
  • 29
    • 33644777700 scopus 로고    scopus 로고
    • Effects of amino acid substitutions in transmembrane domains of the NR1 subunit on the ethanol inhibition of recombinant N-methyl-D-aspartate receptors
    • Smothers C.T., Woodward J.J. Effects of amino acid substitutions in transmembrane domains of the NR1 subunit on the ethanol inhibition of recombinant N-methyl-D-aspartate receptors. Alcohol. Clin. Exp. Res. 2006, 30:523-530.
    • (2006) Alcohol. Clin. Exp. Res. , vol.30 , pp. 523-530
    • Smothers, C.T.1    Woodward, J.J.2
  • 30
    • 34547093859 scopus 로고    scopus 로고
    • Pharmacological characterization of glycine-activated currents in HEK 293 cells expressing N-methyl-D-aspartate NR1 and NR3 subunits
    • Smothers C.T., Woodward J.J. Pharmacological characterization of glycine-activated currents in HEK 293 cells expressing N-methyl-D-aspartate NR1 and NR3 subunits. J. Pharmacol. Exp. Ther. 2007, 322:739-748.
    • (2007) J. Pharmacol. Exp. Ther. , vol.322 , pp. 739-748
    • Smothers, C.T.1    Woodward, J.J.2
  • 31
    • 0031040615 scopus 로고    scopus 로고
    • Characterization of protein kinase A and protein kinase C phosphorylation of the N-methyl-D-aspartate receptor NR1 subunit using phosphorylation site-specific antibodies
    • Tingley W.G., Ehlers M.D., Kameyama K., Doherty C., Ptak J.B., Riley C.T., et al. Characterization of protein kinase A and protein kinase C phosphorylation of the N-methyl-D-aspartate receptor NR1 subunit using phosphorylation site-specific antibodies. J. Biol. Chem. 1997, 272:5157-5166.
    • (1997) J. Biol. Chem. , vol.272 , pp. 5157-5166
    • Tingley, W.G.1    Ehlers, M.D.2    Kameyama, K.3    Doherty, C.4    Ptak, J.B.5    Riley, C.T.6
  • 32
    • 0038290732 scopus 로고    scopus 로고
    • Glutamatergic mechanisms in addiction
    • Tzschentke T.M., Schmidt W.J. Glutamatergic mechanisms in addiction. Mol. Psychiatry 2003, 8:373-382.
    • (2003) Mol. Psychiatry , vol.8 , pp. 373-382
    • Tzschentke, T.M.1    Schmidt, W.J.2
  • 33
    • 0025019986 scopus 로고
    • Ethanol inhibition of N-methyl-D-aspartate-stimulated endogenous dopamine release from rat striatal slices: reversal by glycine
    • Woodward J.J., Gonzales R.A. Ethanol inhibition of N-methyl-D-aspartate-stimulated endogenous dopamine release from rat striatal slices: reversal by glycine. J. Neurochem. 1990, 54:712-715.
    • (1990) J. Neurochem. , vol.54 , pp. 712-715
    • Woodward, J.J.1    Gonzales, R.A.2
  • 34
    • 0030569408 scopus 로고    scopus 로고
    • Single-channel and whole-cell analysis of ethanol inhibition of NMDA-activated currents in cultured mouse cortical and hippocampal neurons
    • Wright J.M., Peoples R.W., Weight F.F. Single-channel and whole-cell analysis of ethanol inhibition of NMDA-activated currents in cultured mouse cortical and hippocampal neurons. Brain Res. 1996, 738:249-256.
    • (1996) Brain Res. , vol.738 , pp. 249-256
    • Wright, J.M.1    Peoples, R.W.2    Weight, F.F.3
  • 35
    • 0034788270 scopus 로고    scopus 로고
    • An ER retention signal explains differences in surface expression of NMDA and AMPA receptor subunits
    • Xia H., Hornby Z.D., Malenka R.C. An ER retention signal explains differences in surface expression of NMDA and AMPA receptor subunits. Neuropharmacology 2001, 41:714-723.
    • (2001) Neuropharmacology , vol.41 , pp. 714-723
    • Xia, H.1    Hornby, Z.D.2    Malenka, R.C.3
  • 36
    • 33644798558 scopus 로고    scopus 로고
    • Ethanol inhibition of NMDA receptors under conditions of altered protein kinase A activity
    • Xu M., Woodward J.J. Ethanol inhibition of NMDA receptors under conditions of altered protein kinase A activity. J. Neurochem. 2006, 96:1760-1767.
    • (2006) J. Neurochem. , vol.96 , pp. 1760-1767
    • Xu, M.1    Woodward, J.J.2
  • 37
    • 46449129315 scopus 로고    scopus 로고
    • Ethanol inhibition of recombinant NMDA receptors is not altered by coexpression of CaMKII-alpha or CaMKII-beta
    • Xu M., Chandler L.J., Woodward J.J. Ethanol inhibition of recombinant NMDA receptors is not altered by coexpression of CaMKII-alpha or CaMKII-beta. Alcohol 2008, 42:425-432.
    • (2008) Alcohol , vol.42 , pp. 425-432
    • Xu, M.1    Chandler, L.J.2    Woodward, J.J.3
  • 38
    • 0033592928 scopus 로고    scopus 로고
    • Protein kinase C potentiation of N-methyl-D-aspartate receptor activity is not mediated by phosphorylation of N-methyl-D-aspartate receptor subunits
    • Zheng X., Zhang L., Wang A.P., Bennett M.V., Zukin R.S. Protein kinase C potentiation of N-methyl-D-aspartate receptor activity is not mediated by phosphorylation of N-methyl-D-aspartate receptor subunits. Proc. Natl. Acad. Sci. U. S. A. 1999, 96:15262-15267.
    • (1999) Proc. Natl. Acad. Sci. U. S. A. , vol.96 , pp. 15262-15267
    • Zheng, X.1    Zhang, L.2    Wang, A.P.3    Bennett, M.V.4    Zukin, R.S.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.