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Volumn 50, Issue 2, 2013, Pages 92-100

Modeling human hematopoietic stem cell biology in the mouse

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE RECEPTOR CXCR4; MONOCLONAL ANTIBODY;

EID: 84884682635     PISSN: 00371963     EISSN: 15328686     Source Type: Journal    
DOI: 10.1053/j.seminhematol.2013.03.029     Document Type: Article
Times cited : (25)

References (80)
  • 1
    • 0030942527 scopus 로고    scopus 로고
    • A common precursor for primitive erythropoiesis and definitive haematopoiesis
    • Kennedy M., Firpo M., Choi K. A common precursor for primitive erythropoiesis and definitive haematopoiesis. Nature 1997, 386:488-493.
    • (1997) Nature , vol.386 , pp. 488-493
    • Kennedy, M.1    Firpo, M.2    Choi, K.3
  • 3
    • 0033405452 scopus 로고    scopus 로고
    • Development of erythroid and myeloid progenitors in the yolk sac and embryo proper of the mouse
    • Palis J., Robertson S., Kennedy M., Wall C., Keller G. Development of erythroid and myeloid progenitors in the yolk sac and embryo proper of the mouse. Development 1999, 126:5073-5084.
    • (1999) Development , vol.126 , pp. 5073-5084
    • Palis, J.1    Robertson, S.2    Kennedy, M.3    Wall, C.4    Keller, G.5
  • 4
    • 34247601504 scopus 로고    scopus 로고
    • Cell tracing shows the contribution of the yolk sac to adult haematopoiesis
    • Samokhvalov I.M., Samokhvalova N.I., Nishikawa S. Cell tracing shows the contribution of the yolk sac to adult haematopoiesis. Nature 2007, 446:1056-1061.
    • (2007) Nature , vol.446 , pp. 1056-1061
    • Samokhvalov, I.M.1    Samokhvalova, N.I.2    Nishikawa, S.3
  • 5
    • 0030595341 scopus 로고    scopus 로고
    • Definitive hematopoiesis is autonomously initiated by the AGM region
    • Medvinsky A., Dzierzak E. Definitive hematopoiesis is autonomously initiated by the AGM region. Cell 1996, 86:897-906.
    • (1996) Cell , vol.86 , pp. 897-906
    • Medvinsky, A.1    Dzierzak, E.2
  • 6
    • 84855487703 scopus 로고    scopus 로고
    • Highly potent human hematopoietic stem cells first emerge in the intraembryonic aorta-gonad-mesonephros region
    • Ivanovs A., Rybtsov S., Welch L., et al. Highly potent human hematopoietic stem cells first emerge in the intraembryonic aorta-gonad-mesonephros region. J Exp Med 2011, 208:2417-2427.
    • (2011) J Exp Med , vol.208 , pp. 2417-2427
    • Ivanovs, A.1    Rybtsov, S.2    Welch, L.3
  • 8
    • 0343236268 scopus 로고
    • The radiation sensitivity of normal mouse bone marrow cells, determined by quantitative marrow transplantation into irradiated mice
    • McCulloch E.A., Till J.E. The radiation sensitivity of normal mouse bone marrow cells, determined by quantitative marrow transplantation into irradiated mice. Radiat Res 1960, 13:115-125.
    • (1960) Radiat Res , vol.13 , pp. 115-125
    • McCulloch, E.A.1    Till, J.E.2
  • 9
    • 0000062301 scopus 로고
    • Cytological demonstration of the clonal nature of spleen colonies derived from transplanted mouse marrow cells
    • Becker A.J., McCulloch EA., Till J.E. Cytological demonstration of the clonal nature of spleen colonies derived from transplanted mouse marrow cells. Nature 1963, 197:452-454.
    • (1963) Nature , vol.197 , pp. 452-454
    • Becker, A.J.1    McCulloch, E.A.2    Till, J.E.3
  • 10
    • 78651158197 scopus 로고
    • A stochastic model of stem cell proliferation, based on the growth of spleen colony-forming cells
    • Till J.E., McCulloch E.A., Siminovitch L. A stochastic model of stem cell proliferation, based on the growth of spleen colony-forming cells. Proc Natl Acad Sci U S A 1964, 51:29-36.
    • (1964) Proc Natl Acad Sci U S A , vol.51 , pp. 29-36
    • Till, J.E.1    McCulloch, E.A.2    Siminovitch, L.3
  • 11
    • 0023922373 scopus 로고
    • Purification and characterization of mouse hematopoietic stem cells
    • Spangrude G.J., Heimfeld S., Weissman I.L. Purification and characterization of mouse hematopoietic stem cells. Science 1988, 241:58-62.
    • (1988) Science , vol.241 , pp. 58-62
    • Spangrude, G.J.1    Heimfeld, S.2    Weissman, I.L.3
  • 12
    • 0026041826 scopus 로고
    • Enrichment and characterization of murine hematopoietic stem cells that express c-kit molecule
    • Okada S., Nakauchi H., Nagayoshi K., et al. Enrichment and characterization of murine hematopoietic stem cells that express c-kit molecule. Blood 1991, 78:1706-1712.
    • (1991) Blood , vol.78 , pp. 1706-1712
    • Okada, S.1    Nakauchi, H.2    Nagayoshi, K.3
  • 13
    • 21244463426 scopus 로고    scopus 로고
    • SLAM family receptors distinguish hematopoietic stem and progenitor cells and reveal endothelial niches for stem cells
    • Kiel M.J., Yilmaz O.H., Iwashita T., Terhorst C., Morrison S.J. SLAM family receptors distinguish hematopoietic stem and progenitor cells and reveal endothelial niches for stem cells. Cell 2005, 121:1109-1121.
    • (2005) Cell , vol.121 , pp. 1109-1121
    • Kiel, M.J.1    Yilmaz, O.H.2    Iwashita, T.3    Terhorst, C.4    Morrison, S.J.5
  • 14
    • 0029796633 scopus 로고    scopus 로고
    • Long-term lymphohematopoietic reconstitution by a single CD34-low/negative hematopoietic stem cell
    • Osawa M., Hanada K., Hamada H., Nakauchi H. Long-term lymphohematopoietic reconstitution by a single CD34-low/negative hematopoietic stem cell. Science 1996, 273:242-245.
    • (1996) Science , vol.273 , pp. 242-245
    • Osawa, M.1    Hanada, K.2    Hamada, H.3    Nakauchi, H.4
  • 15
    • 18344418672 scopus 로고    scopus 로고
    • Functional and phenotypic characterization of cord blood and bone marrow subsets expressing FLT3 (CD135) receptor tyrosine kinase
    • Rappold I., Ziegler B.L., Köhler I. Functional and phenotypic characterization of cord blood and bone marrow subsets expressing FLT3 (CD135) receptor tyrosine kinase. Blood 1997, 90:111-125.
    • (1997) Blood , vol.90 , pp. 111-125
    • Rappold, I.1    Ziegler, B.L.2    Köhler, I.3
  • 16
    • 70349611262 scopus 로고    scopus 로고
    • Estimating dormant and active hematopoietic stem cell kinetics through extensive modeling of bromodeoxyuridine label-retaining cell dynamics
    • van der Wath R.C., Wilson A., Laurenti E., Trumpp A., Lio P. Estimating dormant and active hematopoietic stem cell kinetics through extensive modeling of bromodeoxyuridine label-retaining cell dynamics. PloS One 2009, 4:e6972.
    • (2009) PloS One , vol.4
    • van der Wath, R.C.1    Wilson, A.2    Laurenti, E.3    Trumpp, A.4    Lio, P.5
  • 17
    • 0025761861 scopus 로고
    • Separation of functionally distinct subpopulations of primitive human hematopoietic cells using rhodamine-123
    • Udomsakdi C., Eaves C.J., Sutherland H.J., Lansdorp P.M. Separation of functionally distinct subpopulations of primitive human hematopoietic cells using rhodamine-123. Exp Hematol 1991, 19:338-342.
    • (1991) Exp Hematol , vol.19 , pp. 338-342
    • Udomsakdi, C.1    Eaves, C.J.2    Sutherland, H.J.3    Lansdorp, P.M.4
  • 18
    • 0029958876 scopus 로고    scopus 로고
    • Isolation and functional properties of murine hematopoietic stem cells that are replicating in vivo
    • Goodell M.A., Brose K., Paradis G., Conner A.S., Mulligan R.C. Isolation and functional properties of murine hematopoietic stem cells that are replicating in vivo. J Exp Med 1996, 183:1797-1806.
    • (1996) J Exp Med , vol.183 , pp. 1797-1806
    • Goodell, M.A.1    Brose, K.2    Paradis, G.3    Conner, A.S.4    Mulligan, R.C.5
  • 19
    • 0024213526 scopus 로고
    • Engraftment of immune-deficient mice with human hematopoietic stem cells
    • Kamel-Reid S., Dick J.E. Engraftment of immune-deficient mice with human hematopoietic stem cells. Science 1988, 242:1706-1709.
    • (1988) Science , vol.242 , pp. 1706-1709
    • Kamel-Reid, S.1    Dick, J.E.2
  • 20
    • 79551630105 scopus 로고    scopus 로고
    • Human and rhesus macaque hematopoietic stem cells cannot be purified based only on SLAM family markers
    • Larochelle A., Savona M., Wiggins M. Human and rhesus macaque hematopoietic stem cells cannot be purified based only on SLAM family markers. Blood 2011, 117:1550-1554.
    • (2011) Blood , vol.117 , pp. 1550-1554
    • Larochelle, A.1    Savona, M.2    Wiggins, M.3
  • 21
    • 0034795256 scopus 로고    scopus 로고
    • The ABC transporter Bcrp1/ABCG2 is expressed in a wide variety of stem cells and is a molecular determinant of the side-population phenotype
    • Zhou S., Schuetz J.D., Bunting K.D. The ABC transporter Bcrp1/ABCG2 is expressed in a wide variety of stem cells and is a molecular determinant of the side-population phenotype. Nat Med 2001, 7:1028-1034.
    • (2001) Nat Med , vol.7 , pp. 1028-1034
    • Zhou, S.1    Schuetz, J.D.2    Bunting, K.D.3
  • 22
    • 0028966584 scopus 로고
    • Functional isolation and characterization of human hematopoietic stem cells
    • Berardi A.C., Wang A., Levine J.D., Lopez P., Scadden D.T. Functional isolation and characterization of human hematopoietic stem cells. Science 1995, 267:104-108.
    • (1995) Science , vol.267 , pp. 104-108
    • Berardi, A.C.1    Wang, A.2    Levine, J.D.3    Lopez, P.4    Scadden, D.T.5
  • 23
    • 0036788712 scopus 로고    scopus 로고
    • Evidence that the number of hematopoietic stem cells per animal is conserved in mammals
    • Abkowitz J.L., Catlin S.N., McCallie M.T., Guttorp P. Evidence that the number of hematopoietic stem cells per animal is conserved in mammals. Blood 2002, 100:2665-2667.
    • (2002) Blood , vol.100 , pp. 2665-2667
    • Abkowitz, J.L.1    Catlin, S.N.2    McCallie, M.T.3    Guttorp, P.4
  • 24
    • 0025016163 scopus 로고
    • Resting and activated subsets of mouse multipotent hematopoietic stem cells
    • Spangrude G.J., Johnson G.R. Resting and activated subsets of mouse multipotent hematopoietic stem cells. Proc Natl Acad Sci U S A 1990, 87:7433-7437.
    • (1990) Proc Natl Acad Sci U S A , vol.87 , pp. 7433-7437
    • Spangrude, G.J.1    Johnson, G.R.2
  • 25
    • 28544436371 scopus 로고    scopus 로고
    • Global analysis of proliferation and cell cycle gene expression in the regulation of hematopoietic stem and progenitor cell fates
    • Passegue E., Wagers A.J., Giuriato S., Anderson W.C., Weissman I.L. Global analysis of proliferation and cell cycle gene expression in the regulation of hematopoietic stem and progenitor cell fates. J Exp Med 2005, 202:1599-1611.
    • (2005) J Exp Med , vol.202 , pp. 1599-1611
    • Passegue, E.1    Wagers, A.J.2    Giuriato, S.3    Anderson, W.C.4    Weissman, I.L.5
  • 26
    • 0032980506 scopus 로고    scopus 로고
    • In vivo proliferation and cell cycle kinetics of long-term self-renewing hematopoietic stem cells
    • Cheshier S.H., Morrison S.J., Liao X., Weissman I.L. In vivo proliferation and cell cycle kinetics of long-term self-renewing hematopoietic stem cells. Proc Natl Acad Sci U S A 1999, 96:3120-3125.
    • (1999) Proc Natl Acad Sci U S A , vol.96 , pp. 3120-3125
    • Cheshier, S.H.1    Morrison, S.J.2    Liao, X.3    Weissman, I.L.4
  • 27
    • 0030914867 scopus 로고    scopus 로고
    • Quiescence, cycling, and turnover in the primitive hematopoietic stem cell compartment
    • Bradford G.B., Williams B., Rossi R., Bertoncello I. Quiescence, cycling, and turnover in the primitive hematopoietic stem cell compartment. Exp Hematol 1997, 25:445-453.
    • (1997) Exp Hematol , vol.25 , pp. 445-453
    • Bradford, G.B.1    Williams, B.2    Rossi, R.3    Bertoncello, I.4
  • 28
    • 34548601610 scopus 로고    scopus 로고
    • Haematopoietic stem cells do not asymmetrically segregate chromosomes or retain BrdU
    • Kiel M.J., He S., Ashkenazi R. Haematopoietic stem cells do not asymmetrically segregate chromosomes or retain BrdU. Nature 2007, 449:238-242.
    • (2007) Nature , vol.449 , pp. 238-242
    • Kiel, M.J.1    He, S.2    Ashkenazi, R.3
  • 29
    • 34548405232 scopus 로고    scopus 로고
    • Dormant and self-renewing hematopoietic stem cells and their niches
    • Wilson A., Oser G.M., Jaworski M. Dormant and self-renewing hematopoietic stem cells and their niches. Ann N Y Acad Sci 2007, 1106:64-75.
    • (2007) Ann N Y Acad Sci , vol.1106 , pp. 64-75
    • Wilson, A.1    Oser, G.M.2    Jaworski, M.3
  • 30
    • 60149104597 scopus 로고    scopus 로고
    • Analysis of histone 2B-GFP retention reveals slowly cycling hematopoietic stem cells
    • Foudi A., Hochedlinger K., Van Buren D. Analysis of histone 2B-GFP retention reveals slowly cycling hematopoietic stem cells. Nat Biotechnol 2009, 27:84-90.
    • (2009) Nat Biotechnol , vol.27 , pp. 84-90
    • Foudi, A.1    Hochedlinger, K.2    Van Buren, D.3
  • 31
    • 0035874515 scopus 로고    scopus 로고
    • The relative quiescence of hematopoietic stem cells in nonhuman primates
    • Mahmud N., Devine S.M., Weller K.P. The relative quiescence of hematopoietic stem cells in nonhuman primates. Blood 2001, 97:3061-3068.
    • (2001) Blood , vol.97 , pp. 3061-3068
    • Mahmud, N.1    Devine, S.M.2    Weller, K.P.3
  • 32
    • 79955974343 scopus 로고    scopus 로고
    • The replication rate of human hematopoietic stem cells in vivo
    • Catlin S.N., Busque L., Gale R.E., Guttorp P., Abkowitz J.L. The replication rate of human hematopoietic stem cells in vivo. Blood 2011, 117:4460-4466.
    • (2011) Blood , vol.117 , pp. 4460-4466
    • Catlin, S.N.1    Busque, L.2    Gale, R.E.3    Guttorp, P.4    Abkowitz, J.L.5
  • 34
    • 0025148776 scopus 로고
    • The architecture of bone marrow cell populations
    • Lord B.I. The architecture of bone marrow cell populations. Int J Cell Cloning 1990, 8:317-331.
    • (1990) Int J Cell Cloning , vol.8 , pp. 317-331
    • Lord, B.I.1
  • 35
    • 0017694555 scopus 로고
    • Conditions controlling the proliferation of hemopoietic stem cells in vitro
    • Dexter T.M., Allen T.D., Lajha L.G. Conditions controlling the proliferation of hemopoietic stem cells in vitro. J Cell Physiol 1977, 91:335-344.
    • (1977) J Cell Physiol , vol.91 , pp. 335-344
    • Dexter, T.M.1    Allen, T.D.2    Lajha, L.G.3
  • 36
    • 0018102359 scopus 로고
    • The relationship between the spleen colony-forming cell and the haemopoietic stem cell
    • Schofield R. The relationship between the spleen colony-forming cell and the haemopoietic stem cell. Blood Cells 1978, 4:7-25.
    • (1978) Blood Cells , vol.4 , pp. 7-25
    • Schofield, R.1
  • 37
    • 0242363225 scopus 로고    scopus 로고
    • Identification of the haematopoietic stem cell niche and control of the niche size
    • Zhang J., Niu C., Ye L., Huang H. Identification of the haematopoietic stem cell niche and control of the niche size. Nature 2003, 425:836-841.
    • (2003) Nature , vol.425 , pp. 836-841
    • Zhang, J.1    Niu, C.2    Ye, L.3    Huang, H.4
  • 38
    • 0242268524 scopus 로고    scopus 로고
    • Osteoblastic cells regulate the haematopoietic stem cell niche
    • Calvi L.M., Adams G.B., Weibrecht K.W. Osteoblastic cells regulate the haematopoietic stem cell niche. Nature 2003, 425:841-846.
    • (2003) Nature , vol.425 , pp. 841-846
    • Calvi, L.M.1    Adams, G.B.2    Weibrecht, K.W.3
  • 39
    • 81855183667 scopus 로고    scopus 로고
    • Nonmyelinating Schwann cells maintain hematopoietic stem cell hibernation in the bone marrow niche
    • Yamazaki S., Ema H., Karlsson G. Nonmyelinating Schwann cells maintain hematopoietic stem cell hibernation in the bone marrow niche. Cell 2011, 147:1146-1158.
    • (2011) Cell , vol.147 , pp. 1146-1158
    • Yamazaki, S.1    Ema, H.2    Karlsson, G.3
  • 40
    • 77449121923 scopus 로고    scopus 로고
    • Endothelial cells are essential for the self-renewal and repopulation of Notch-dependent hematopoietic stem cells
    • Butler J.M., Nolan D.J., Vertes E.L. Endothelial cells are essential for the self-renewal and repopulation of Notch-dependent hematopoietic stem cells. Cell Stem Cell 2010, 6:251-264.
    • (2010) Cell Stem Cell , vol.6 , pp. 251-264
    • Butler, J.M.1    Nolan, D.J.2    Vertes, E.L.3
  • 41
    • 84874327921 scopus 로고    scopus 로고
    • Tie2(+) bone marrow endothelial cells regulate hematopoietic stem cell regeneration following radiation injury
    • Doan P.L., Russell J.L., Himburg H.A. Tie2(+) bone marrow endothelial cells regulate hematopoietic stem cell regeneration following radiation injury. Stem Cells 2013, 31:327-337.
    • (2013) Stem Cells , vol.31 , pp. 327-337
    • Doan, P.L.1    Russell, J.L.2    Himburg, H.A.3
  • 42
    • 39749164920 scopus 로고    scopus 로고
    • Haematopoietic stem cell release is regulated by circadian oscillations
    • Mendez-Ferrer S., Lucas D., Battista M., Frenette P.S. Haematopoietic stem cell release is regulated by circadian oscillations. Nature 2008, 452:442-447.
    • (2008) Nature , vol.452 , pp. 442-447
    • Mendez-Ferrer, S.1    Lucas, D.2    Battista, M.3    Frenette, P.S.4
  • 43
    • 77958553682 scopus 로고    scopus 로고
    • Bone marrow macrophages maintain hematopoietic stem cell (HSC) niches and their depletion mobilizes HSCs
    • Winkler I.G., Sims N.A., Pettit A.R. Bone marrow macrophages maintain hematopoietic stem cell (HSC) niches and their depletion mobilizes HSCs. Blood 2010, 116:4815-4828.
    • (2010) Blood , vol.116 , pp. 4815-4828
    • Winkler, I.G.1    Sims, N.A.2    Pettit, A.R.3
  • 44
    • 79951694373 scopus 로고    scopus 로고
    • Bone marrow CD169+ macrophages promote the retention of hematopoietic stem and progenitor cells in the mesenchymal stem cell niche
    • Chow A., Lucas D., Hidalgo A. Bone marrow CD169+ macrophages promote the retention of hematopoietic stem and progenitor cells in the mesenchymal stem cell niche. J Exp Med 2011, 208:261-271.
    • (2011) J Exp Med , vol.208 , pp. 261-271
    • Chow, A.1    Lucas, D.2    Hidalgo, A.3
  • 45
    • 33744983304 scopus 로고    scopus 로고
    • Osteoclasts degrade endosteal components and promote mobilization of hematopoietic progenitor cells
    • Kollet O., Dar A., Shivtiel S. Osteoclasts degrade endosteal components and promote mobilization of hematopoietic progenitor cells. Nat Med 2006, 12:657-664.
    • (2006) Nat Med , vol.12 , pp. 657-664
    • Kollet, O.1    Dar, A.2    Shivtiel, S.3
  • 46
    • 27644517442 scopus 로고    scopus 로고
    • G-CSF potently inhibits osteoblast activity and CXCL12 mRNA expression in the bone marrow
    • Semerad C.L., Christopher M.J., Liu F. G-CSF potently inhibits osteoblast activity and CXCL12 mRNA expression in the bone marrow. Blood 2005, 106:3020-3027.
    • (2005) Blood , vol.106 , pp. 3020-3027
    • Semerad, C.L.1    Christopher, M.J.2    Liu, F.3
  • 47
    • 31044450303 scopus 로고    scopus 로고
    • Signals from the sympathetic nervous system regulate hematopoietic stem cell egress from bone marrow
    • Katayama Y., Battista M., Kao W.M. Signals from the sympathetic nervous system regulate hematopoietic stem cell egress from bone marrow. Cell 2006, 124:407-421.
    • (2006) Cell , vol.124 , pp. 407-421
    • Katayama, Y.1    Battista, M.2    Kao, W.M.3
  • 48
    • 67650504733 scopus 로고    scopus 로고
    • Bone-marrow adipocytes as negative regulators of the haematopoietic microenvironment
    • Naveiras O., Nardi V., Wenzel P.L. Bone-marrow adipocytes as negative regulators of the haematopoietic microenvironment. Nature 2009, 460:259-263.
    • (2009) Nature , vol.460 , pp. 259-263
    • Naveiras, O.1    Nardi, V.2    Wenzel, P.L.3
  • 49
    • 77955646193 scopus 로고    scopus 로고
    • Mesenchymal and haematopoietic stem cells form a unique bone marrow niche. Nature
    • Méndez-Ferrer S, Michurina TV, Ferraro F. Mesenchymal and haematopoietic stem cells form a unique bone marrow niche. Nature. 466:829-834.
    • , vol.466 , pp. 829-834
    • Méndez-Ferrer, S.1    Michurina, T.V.2    Ferraro, F.3
  • 50
    • 84856147560 scopus 로고    scopus 로고
    • Endothelial and perivascular cells maintain haematopoietic stem cells
    • Ding L., Saunders T.L., Enikolopov G., Morrison S.J. Endothelial and perivascular cells maintain haematopoietic stem cells. Nature 2012, 481:457-462.
    • (2012) Nature , vol.481 , pp. 457-462
    • Ding, L.1    Saunders, T.L.2    Enikolopov, G.3    Morrison, S.J.4
  • 51
    • 80054035544 scopus 로고    scopus 로고
    • Diabetes impairs hematopoietic stem cell mobilization by altering niche function
    • 104ra101
    • Ferraro F, Lymperi S, Méndez-Ferrer S. Diabetes impairs hematopoietic stem cell mobilization by altering niche function. Sci Translat Med. 2011;3:104ra101.
    • (2011) Sci Translat Med , vol.3
    • Ferraro F.Lymperi, S.1    Méndez-Ferrer, S.2
  • 52
    • 0033119201 scopus 로고    scopus 로고
    • The chemokine receptor CXCR4 is required for the retention of B lineage and granulocytic precursors within the bone marrow microenvironment
    • Ma Q., Jones D., Springer T.A. The chemokine receptor CXCR4 is required for the retention of B lineage and granulocytic precursors within the bone marrow microenvironment. Immunity 1999, 10:463-471.
    • (1999) Immunity , vol.10 , pp. 463-471
    • Ma, Q.1    Jones, D.2    Springer, T.A.3
  • 53
    • 0033545938 scopus 로고    scopus 로고
    • A cell-autonomous requirement for CXCR4 in long-term lymphoid and myeloid reconstitution
    • Kawabata K., Ujikawa M., Egawa T. A cell-autonomous requirement for CXCR4 in long-term lymphoid and myeloid reconstitution. Proc Natl Acad Sci U S A 1999, 96:5663-5667.
    • (1999) Proc Natl Acad Sci U S A , vol.96 , pp. 5663-5667
    • Kawabata, K.1    Ujikawa, M.2    Egawa, T.3
  • 54
    • 0035871880 scopus 로고    scopus 로고
    • CXCR-4 desensitization is associated with tissue localization of hemopoietic progenitor cells
    • Shen H., Cheng T., Olszak I. CXCR-4 desensitization is associated with tissue localization of hemopoietic progenitor cells. J Immunol 2001, 166:5027-5033.
    • (2001) J Immunol , vol.166 , pp. 5027-5033
    • Shen, H.1    Cheng, T.2    Olszak, I.3
  • 55
    • 0031440743 scopus 로고    scopus 로고
    • Antibodies to VLA4 integrin mobilize long-term repopulating cells and augment cytokine-induced mobilization in primates and mice
    • Craddock C.F., Nakamoto B., Andrews R.G., Priestley G.V., Papayannopoulou T. Antibodies to VLA4 integrin mobilize long-term repopulating cells and augment cytokine-induced mobilization in primates and mice. Blood 1997, 90:4779-4788.
    • (1997) Blood , vol.90 , pp. 4779-4788
    • Craddock, C.F.1    Nakamoto, B.2    Andrews, R.G.3    Priestley, G.V.4    Papayannopoulou, T.5
  • 56
    • 34250883337 scopus 로고    scopus 로고
    • Prostaglandin E2 regulates vertebrate haematopoietic stem cell homeostasis
    • North T.E., Goessling W., Walkley C.R. Prostaglandin E2 regulates vertebrate haematopoietic stem cell homeostasis. Nature 2007, 447:1007-1011.
    • (2007) Nature , vol.447 , pp. 1007-1011
    • North, T.E.1    Goessling, W.2    Walkley, C.R.3
  • 57
    • 65549159488 scopus 로고    scopus 로고
    • Haematopoietic stem cells depend on Galpha(s)-mediated signalling to engraft bone marrow
    • Adams G.B., Alley I.R., Chung U.I. Haematopoietic stem cells depend on Galpha(s)-mediated signalling to engraft bone marrow. Nature 2009, 459:103-107.
    • (2009) Nature , vol.459 , pp. 103-107
    • Adams, G.B.1    Alley, I.R.2    Chung, U.I.3
  • 58
    • 33846869023 scopus 로고    scopus 로고
    • Therapeutic targeting of a stem cell niche
    • Adams G.B., Martin R.P., Alley I.R. Therapeutic targeting of a stem cell niche. Nat Biotechnol 2007, 25:238-243.
    • (2007) Nat Biotechnol , vol.25 , pp. 238-243
    • Adams, G.B.1    Martin, R.P.2    Alley, I.R.3
  • 59
    • 84873575928 scopus 로고    scopus 로고
    • Myelopoiesis is regulated by osteocytes through Gsalpha-dependent signaling
    • Fulzele K., Krause D.S., Panaroni C. Myelopoiesis is regulated by osteocytes through Gsalpha-dependent signaling. Blood 2013, 121:930-939.
    • (2013) Blood , vol.121 , pp. 930-939
    • Fulzele, K.1    Krause, D.S.2    Panaroni, C.3
  • 60
    • 34250331610 scopus 로고    scopus 로고
    • A microenvironment-induced myeloproliferative syndrome caused by retinoic acid receptor gamma deficiency
    • Walkley C.R., Olsen G.H., Dworkin S. A microenvironment-induced myeloproliferative syndrome caused by retinoic acid receptor gamma deficiency. Cell 2007, 129:1097-1110.
    • (2007) Cell , vol.129 , pp. 1097-1110
    • Walkley, C.R.1    Olsen, G.H.2    Dworkin, S.3
  • 61
    • 79960139808 scopus 로고    scopus 로고
    • Crebbp haploinsufficiency in mice alters the bone marrow microenvironment, leading to loss of stem cells and excessive myelopoiesis
    • Zimmer S.N., Zhou Q., Zhou T. Crebbp haploinsufficiency in mice alters the bone marrow microenvironment, leading to loss of stem cells and excessive myelopoiesis. Blood 2011, 118:69-79.
    • (2011) Blood , vol.118 , pp. 69-79
    • Zimmer, S.N.1    Zhou, Q.2    Zhou, T.3
  • 62
    • 77950862042 scopus 로고    scopus 로고
    • Bone progenitor dysfunction induces myelodysplasia and secondary leukaemia
    • Raaijmakers M.H., Mukherjee S., Guo S. Bone progenitor dysfunction induces myelodysplasia and secondary leukaemia. Nature 2010, 464:852-857.
    • (2010) Nature , vol.464 , pp. 852-857
    • Raaijmakers, M.H.1    Mukherjee, S.2    Guo, S.3
  • 63
    • 67651098996 scopus 로고    scopus 로고
    • Altered cellular dynamics and endosteal location of aged early hematopoietic progenitor cells revealed by time-lapse intravital imaging in long bones
    • Köhler A., Schmithorst V., Filippi M.D. Altered cellular dynamics and endosteal location of aged early hematopoietic progenitor cells revealed by time-lapse intravital imaging in long bones. Blood 2009, 114:290-298.
    • (2009) Blood , vol.114 , pp. 290-298
    • Köhler, A.1    Schmithorst, V.2    Filippi, M.D.3
  • 64
    • 84864648787 scopus 로고    scopus 로고
    • Aging of the microenvironment influences clonality in hematopoiesis
    • Vas V., Senger K., Dorr K., Niebel A., Geiger H. Aging of the microenvironment influences clonality in hematopoiesis. PloS One 2012, 7:e42080.
    • (2012) PloS One , vol.7
    • Vas, V.1    Senger, K.2    Dorr, K.3    Niebel, A.4    Geiger, H.5
  • 65
    • 42949095542 scopus 로고    scopus 로고
    • Dysregulation of IL-32 in myelodysplastic syndrome and chronic myelomonocytic leukemia modulates apoptosis and impairs NK function
    • Marcondes A.M., Mhyre A.J. Dysregulation of IL-32 in myelodysplastic syndrome and chronic myelomonocytic leukemia modulates apoptosis and impairs NK function. Proc Natl Acad Sci U S A 2008, 105:2865-2870.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 2865-2870
    • Marcondes, A.M.1    Mhyre, A.J.2
  • 66
    • 81555196340 scopus 로고    scopus 로고
    • Mesenchymal stromal cells of myelodysplastic syndrome and acute myeloid leukemia patients have distinct genetic abnormalities compared with leukemic blasts
    • Blau O., Baldus C.D., Hofmann W.K. Mesenchymal stromal cells of myelodysplastic syndrome and acute myeloid leukemia patients have distinct genetic abnormalities compared with leukemic blasts. Blood 2011, 118:5583-5592.
    • (2011) Blood , vol.118 , pp. 5583-5592
    • Blau, O.1    Baldus, C.D.2    Hofmann, W.K.3
  • 67
    • 84055200841 scopus 로고    scopus 로고
    • Human bone marrow hematopoietic stem cells are increased in frequency and myeloid-biased with age
    • Pang W.W., Price E.A., Sahoo D. Human bone marrow hematopoietic stem cells are increased in frequency and myeloid-biased with age. Proc Natl Acad Sci U S A 2011, 108:20012-20017.
    • (2011) Proc Natl Acad Sci U S A , vol.108 , pp. 20012-20017
    • Pang, W.W.1    Price, E.A.2    Sahoo, D.3
  • 68
    • 79955951566 scopus 로고    scopus 로고
    • Age-related changes in human hematopoietic stem/progenitor cells
    • Kuranda K., Vargaftig J., de la Rochere P. Age-related changes in human hematopoietic stem/progenitor cells. Aging Cell 2011, 10:542-546.
    • (2011) Aging Cell , vol.10 , pp. 542-546
    • Kuranda, K.1    Vargaftig, J.2    de la Rochere, P.3
  • 69
    • 23744439044 scopus 로고    scopus 로고
    • Effects of aging on the homing and engraftment of murine hematopoietic stem and progenitor cells
    • Liang Y., Van Zant G., Szilvassy S.J. Effects of aging on the homing and engraftment of murine hematopoietic stem and progenitor cells. Blood 2005, 106:1479-1487.
    • (2005) Blood , vol.106 , pp. 1479-1487
    • Liang, Y.1    Van Zant, G.2    Szilvassy, S.J.3
  • 70
    • 0035496909 scopus 로고    scopus 로고
    • Donor characteristics as risk factors in recipients after transplantation of bone marrow from unrelated donors: the effect of donor age
    • Kollman C., Howe C.W., Anasetti C. Donor characteristics as risk factors in recipients after transplantation of bone marrow from unrelated donors: the effect of donor age. Blood 2001, 98:2043-2051.
    • (2001) Blood , vol.98 , pp. 2043-2051
    • Kollman, C.1    Howe, C.W.2    Anasetti, C.3
  • 72
    • 47049099198 scopus 로고    scopus 로고
    • A new mechanism for the aging of hematopoietic stem cells: aging changes the clonal composition of the stem cell compartment but not individual stem cells
    • Cho R.H., Sieburg H.B., Muller-Sieburg C.E. A new mechanism for the aging of hematopoietic stem cells: aging changes the clonal composition of the stem cell compartment but not individual stem cells. Blood 2008, 111:5553-5561.
    • (2008) Blood , vol.111 , pp. 5553-5561
    • Cho, R.H.1    Sieburg, H.B.2    Muller-Sieburg, C.E.3
  • 73
    • 77950418688 scopus 로고    scopus 로고
    • Functionally distinct hematopoietic stem cells modulate hematopoietic lineage potential during aging by a mechanism of clonal expansion
    • Beerman I., Bhattacharya D., Zandi S. Functionally distinct hematopoietic stem cells modulate hematopoietic lineage potential during aging by a mechanism of clonal expansion. Proc Natl Acad Sci U S A 2010, 107:5465-5470.
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 5465-5470
    • Beerman, I.1    Bhattacharya, D.2    Zandi, S.3
  • 74
    • 79960106880 scopus 로고    scopus 로고
    • Isolation of single human hematopoietic stem cells capable of long-term multilineage engraftment
    • Notta F., Doulatov S., Laurenti E. Isolation of single human hematopoietic stem cells capable of long-term multilineage engraftment. Science 2011, 333:218-221.
    • (2011) Science , vol.333 , pp. 218-221
    • Notta, F.1    Doulatov, S.2    Laurenti, E.3
  • 75
    • 34548208677 scopus 로고    scopus 로고
    • Aging hematopoietic stem cells decline in function and exhibit epigenetic dysregulation
    • Chambers S.M., Shaw C.A., Gatza C. Aging hematopoietic stem cells decline in function and exhibit epigenetic dysregulation. PLoS Biol 2007, 5:e201.
    • (2007) PLoS Biol , vol.5
    • Chambers, S.M.1    Shaw, C.A.2    Gatza, C.3
  • 76
    • 34250007142 scopus 로고    scopus 로고
    • Deficiencies in DNA damage repair limit the function of haematopoietic stem cells with age
    • Rossi D.J., Bryder D., Seita J. Deficiencies in DNA damage repair limit the function of haematopoietic stem cells with age. Nature 2007, 447:725-729.
    • (2007) Nature , vol.447 , pp. 725-729
    • Rossi, D.J.1    Bryder, D.2    Seita, J.3
  • 77
    • 79952338609 scopus 로고    scopus 로고
    • Accumulation of DNA damage in hematopoietic stem and progenitor cells during human aging
    • Schanz S., Schuler N., Lorat Y. Accumulation of DNA damage in hematopoietic stem and progenitor cells during human aging. PloS One 2011, 6:e17487.
    • (2011) PloS One , vol.6
    • Schanz, S.1    Schuler, N.2    Lorat, Y.3
  • 78
    • 0033518188 scopus 로고    scopus 로고
    • A telomerase component is defective in the human disease dyskeratosis congenita
    • Mitchell J.R., Wood E., Collins K. A telomerase component is defective in the human disease dyskeratosis congenita. Nature 1999, 402:551-555.
    • (1999) Nature , vol.402 , pp. 551-555
    • Mitchell, J.R.1    Wood, E.2    Collins, K.3
  • 79
    • 84867878909 scopus 로고    scopus 로고
    • Conditional TRF1 knockout in the hematopoietic compartment leads to bone marrow failure and recapitulates clinical features of dyskeratosis congenita
    • Beier F., Foronda M., Martinez P., Blasco M.A. Conditional TRF1 knockout in the hematopoietic compartment leads to bone marrow failure and recapitulates clinical features of dyskeratosis congenita. Blood 2012, 120:2990-3000.
    • (2012) Blood , vol.120 , pp. 2990-3000
    • Beier, F.1    Foronda, M.2    Martinez, P.3    Blasco, M.A.4
  • 80
    • 0033525558 scopus 로고    scopus 로고
    • Longevity, stress response, and cancer in aging telomerase-deficient mice
    • Rudolph K.L., Chang S., Lee H.W. Longevity, stress response, and cancer in aging telomerase-deficient mice. Cell 1999, 96:701-712.
    • (1999) Cell , vol.96 , pp. 701-712
    • Rudolph, K.L.1    Chang, S.2    Lee, H.W.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.