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Volumn 105, Issue 8, 2008, Pages 2865-2870

Dysregulation of IL-32 in myelodysplastic syndrome and chronic myelomonocytic leukemia modulates apoptosis and impairs NK function

Author keywords

Marrow stroma; TNF

Indexed keywords

CYTOKINE; INTERLEUKIN 2; INTERLEUKIN 32; MESSENGER RNA; SMALL INTERFERING RNA; TUMOR NECROSIS FACTOR ALPHA; VASCULOTROPIN; CD56 ANTIGEN; IL32 PROTEIN, HUMAN; INTERLEUKIN DERIVATIVE;

EID: 42949095542     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0712391105     Document Type: Article
Times cited : (121)

References (35)
  • 1
    • 44249106051 scopus 로고    scopus 로고
    • eds Appelbaum FR, Forman SJ, Negrin RS, Blume KG Blackwell, Oxford, 4th Ed
    • Deeg HJ (2007) in Thomas' Hematopoietic Cell Transplantation, eds Appelbaum FR, Forman SJ, Negrin RS, Blume KG (Blackwell, Oxford), 4th Ed.
    • (2007) Thomas' Hematopoietic Cell Transplantation
    • Deeg, H.J.1
  • 2
    • 33646196925 scopus 로고    scopus 로고
    • Allogeneic transplantation for the elderly patient with acute myelogenous leukemia or myelodysplastic syndrome
    • de Lima M, Giralt, S (2006) Allogeneic transplantation for the elderly patient with acute myelogenous leukemia or myelodysplastic syndrome. Semin Hematol 43:107-117.
    • (2006) Semin Hematol , vol.43 , pp. 107-117
    • de Lima, M.1    Giralt, S.2
  • 3
    • 10144232108 scopus 로고    scopus 로고
    • Indication of an involvement of interleukin-1 beta converting enzyme-like protease in intramedullary apoptotic cell death in the bone marrow of patients with myelodysplastic syndromes
    • Mundle SD, et al. (1996) Indication of an involvement of interleukin-1 beta converting enzyme-like protease in intramedullary apoptotic cell death in the bone marrow of patients with myelodysplastic syndromes. Blood 88:2640-2647.
    • (1996) Blood , vol.88 , pp. 2640-2647
    • Mundle, S.D.1
  • 4
    • 0031656518 scopus 로고    scopus 로고
    • A role for tumor necrosis factor-α, Fas and Fas-Ligand in marrow failure associated with myelodysplastic syndrome
    • Gersuk GM, et al. (1998) A role for tumor necrosis factor-α, Fas and Fas-Ligand in marrow failure associated with myelodysplastic syndrome. Br J Haematol 103:176-188.
    • (1998) Br J Haematol , vol.103 , pp. 176-188
    • Gersuk, G.M.1
  • 5
    • 0035892123 scopus 로고    scopus 로고
    • Expression of tumor necrosis factor-related apoptosis-inducing ligand, Apo2L, and its receptors in myelodysplastic syndrome: Effects on in vitro hemopoiesis
    • Zang DY, Goodwin RG, Loken MR, Bryant E, Deeg HJ (2001) Expression of tumor necrosis factor-related apoptosis-inducing ligand, Apo2L, and its receptors in myelodysplastic syndrome: effects on in vitro hemopoiesis. Blood 98:3058-3065.
    • (2001) Blood , vol.98 , pp. 3058-3065
    • Zang, D.Y.1    Goodwin, R.G.2    Loken, M.R.3    Bryant, E.4    Deeg, H.J.5
  • 6
    • 0035283119 scopus 로고    scopus 로고
    • Vascular endothelial cell growth factor is an autocrine promoter of abnormal localized immature myeloid precursors and leukemia progenitor formation in myelodysplastic syndromes
    • Bellamy WT, et al. (2001) Vascular endothelial cell growth factor is an autocrine promoter of abnormal localized immature myeloid precursors and leukemia progenitor formation in myelodysplastic syndromes. Blood 97:1427-1434.
    • (2001) Blood , vol.97 , pp. 1427-1434
    • Bellamy, W.T.1
  • 7
    • 4544319588 scopus 로고    scopus 로고
    • Hematologic responses of patients with MDS to antithymocyte globulin plus etanercept correlate with improved flow scores of marrow cells
    • Deeg HJ, et al. (2004) Hematologic responses of patients with MDS to antithymocyte globulin plus etanercept correlate with improved flow scores of marrow cells. Leuk Res 28:1177-1180.
    • (2004) Leuk Res , vol.28 , pp. 1177-1180
    • Deeg, H.J.1
  • 8
    • 4444324472 scopus 로고    scopus 로고
    • Simultaneous demonstration of clonal chromosome abnormalities and apoptosis in individual marrow cells in myelodysplastic syndrome
    • Li X, Bryant E, Deeg HJ (2004) Simultaneous demonstration of clonal chromosome abnormalities and apoptosis in individual marrow cells in myelodysplastic syndrome. Int J Hematol 80:140-145.
    • (2004) Int J Hematol , vol.80 , pp. 140-145
    • Li, X.1    Bryant, E.2    Deeg, H.J.3
  • 9
    • 28444479122 scopus 로고    scopus 로고
    • NF-κB and FLIP in arsenic trioxide (ATO)-induced apoptosis in myelodysplastic syndromes (MDSs)
    • Kerbauy DMB, et al. (2005)NF-κB and FLIP in arsenic trioxide (ATO)-induced apoptosis in myelodysplastic syndromes (MDSs). Blood 106:3917-3925.
    • (2005) Blood , vol.106 , pp. 3917-3925
    • Kerbauy, D.M.B.1
  • 10
    • 7344223859 scopus 로고    scopus 로고
    • Haematological response of patients with myelodysplastic syndrome to antithymocyte globulin is associated with a loss of lymphocyte-mediated inhibition of CFU-GM and alterations in T-cell receptor Vbeta profiles
    • Molldrem JJ, et al. (1998) Haematological response of patients with myelodysplastic syndrome to antithymocyte globulin is associated with a loss of lymphocyte-mediated inhibition of CFU-GM and alterations in T-cell receptor Vbeta profiles. Br J Haematol 102:1314-1322.
    • (1998) Br J Haematol , vol.102 , pp. 1314-1322
    • Molldrem, J.J.1
  • 11
    • 0034022396 scopus 로고    scopus 로고
    • Negative regulators of hemopoiesis and stroma function in patients with myelodysplastic syndrome
    • Deeg HJ, et al. (2000) Negative regulators of hemopoiesis and stroma function in patients with myelodysplastic syndrome. Leuk Lymphoma 37:405-414.
    • (2000) Leuk Lymphoma , vol.37 , pp. 405-414
    • Deeg, H.J.1
  • 12
    • 38349113450 scopus 로고    scopus 로고
    • TNF induced gene expression in human marrow stroma: Clues to the pathophysiology of MDS
    • Stirewalt DL, et al. (2008) TNF induced gene expression in human marrow stroma: Clues to the pathophysiology of MDS. Br J Haematol 140:444-453.
    • (2008) Br J Haematol , vol.140 , pp. 444-453
    • Stirewalt, D.L.1
  • 13
    • 34547887644 scopus 로고    scopus 로고
    • Epithelial overexpression of interleukin-32alpha in inflammatory bowel disease
    • Shioya M, et al. (2007) Epithelial overexpression of interleukin-32alpha in inflammatory bowel disease. Clin Exp Immunol 149:480-486.
    • (2007) Clin Exp Immunol , vol.149 , pp. 480-486
    • Shioya, M.1
  • 14
    • 33750299010 scopus 로고    scopus 로고
    • IL-32, a novel cytokine with a possible role in disease
    • Dinarello CA, Kim SH (2006) IL-32, a novel cytokine with a possible role in disease. Ann Rheum Dis 65(Suppl 3):iii61-iii64.
    • (2006) Ann Rheum Dis , vol.65 , Issue.SUPPL. 3
    • Dinarello, C.A.1    Kim, S.H.2
  • 15
    • 33644765841 scopus 로고    scopus 로고
    • IL-32, a proinflammatory cytokine in rheumatoid arthritis
    • Joosten LA, et al. (2006) IL-32, a proinflammatory cytokine in rheumatoid arthritis. Proc Natl Acad Sci USA 103:3298-3303.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 3298-3303
    • Joosten, L.A.1
  • 16
    • 28044453314 scopus 로고    scopus 로고
    • IL-32 synergizes with nucleotide oligomerization domain (NOD) 1 and NOD2 ligands for IL-1beta and IL-6 production through a caspase 1-dependent mechanism
    • Netea MG, et al. (2005) IL-32 synergizes with nucleotide oligomerization domain (NOD) 1 and NOD2 ligands for IL-1beta and IL-6 production through a caspase 1-dependent mechanism. Proc Natl Acad Sci USA 102:16309-16314.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 16309-16314
    • Netea, M.G.1
  • 17
    • 12444304581 scopus 로고    scopus 로고
    • Interleukin-32: A cytokine and inducer of TNFalpha
    • Kim SH, et al. (2005) Interleukin-32: A cytokine and inducer of TNFalpha. Immunity 22:131-142.
    • (2005) Immunity , vol.22 , pp. 131-142
    • Kim, S.H.1
  • 18
    • 0019952276 scopus 로고
    • Proposals for the classification of the myelodysplastic syndromes
    • Bennett JM, et al. (1982) Proposals for the classification of the myelodysplastic syndromes. Br J Haematol 51:189-199.
    • (1982) Br J Haematol , vol.51 , pp. 189-199
    • Bennett, J.M.1
  • 19
    • 0036786901 scopus 로고    scopus 로고
    • The World Health Organization (WHO) classification of the myeloid neoplasm
    • Vardiman JW, Harris NL, Brunning RD (2002) The World Health Organization (WHO) classification of the myeloid neoplasm. Blood 100:2292-2302.
    • (2002) Blood , vol.100 , pp. 2292-2302
    • Vardiman, J.W.1    Harris, N.L.2    Brunning, R.D.3
  • 20
    • 17544385520 scopus 로고    scopus 로고
    • Biological significance of proliferation, apoptosis, cytokines, and monocyte/macrophage cells in bone marrow biopsies of 145 patients with myelodysplastic syndrome
    • Allampallam K, et al. (2002) Biological significance of proliferation, apoptosis, cytokines, and monocyte/macrophage cells in bone marrow biopsies of 145 patients with myelodysplastic syndrome. Int J Hematol 75:289-297.
    • (2002) Int J Hematol , vol.75 , pp. 289-297
    • Allampallam, K.1
  • 21
    • 0033624913 scopus 로고    scopus 로고
    • Detection of TNFalpha expression in the bone marrow and determination of TNFalpha production of peripheral blood mononuclear cells in myelodysplastic syndrome
    • Molnar L, Berki T, Hussain A, Nemeth P, Losonczy H. (2000) Detection of TNFalpha expression in the bone marrow and determination of TNFalpha production of peripheral blood mononuclear cells in myelodysplastic syndrome. Pathol Oncol Res 6:18-23.
    • (2000) Pathol Oncol Res , vol.6 , pp. 18-23
    • Molnar, L.1    Berki, T.2    Hussain, A.3    Nemeth, P.4    Losonczy, H.5
  • 22
    • 15844405224 scopus 로고    scopus 로고
    • Novel insights into the biology of myelodysplastic syndromes: Excessive apoptosis and the role of cytokines
    • Raza A, et al. (1996) Novel insights into the biology of myelodysplastic syndromes: Excessive apoptosis and the role of cytokines. Int J Hematol 63:265-278.
    • (1996) Int J Hematol , vol.63 , pp. 265-278
    • Raza, A.1
  • 23
    • 31544432072 scopus 로고    scopus 로고
    • Involvement of IL-32 in activation-induced cell death in T cells
    • Goda C, et al. (2006) Involvement of IL-32 in activation-induced cell death in T cells. Int Immunol 18:233-240.
    • (2006) Int Immunol , vol.18 , pp. 233-240
    • Goda, C.1
  • 24
    • 0031464758 scopus 로고    scopus 로고
    • Overexpression of tumor necrosis factor (TNF)-alpha and interferon (IFN)-gamma by bone marrow cells from patients with myelodysplastic syndromes
    • Kitagawa M, et al. (1997) Overexpression of tumor necrosis factor (TNF)-alpha and interferon (IFN)-gamma by bone marrow cells from patients with myelodysplastic syndromes. Leukemia 11:2049-2054.
    • (1997) Leukemia , vol.11 , pp. 2049-2054
    • Kitagawa, M.1
  • 25
    • 34547412408 scopus 로고    scopus 로고
    • Differential effects of bexatrone on intrinsic and extrinsic pathways in TRAIL-induced apoptosis in two myeloid leukemia cell lines
    • Ying SX, et al. (2007) Differential effects of bexatrone on intrinsic and extrinsic pathways in TRAIL-induced apoptosis in two myeloid leukemia cell lines. Leuk Lymphoma 48:1003-1014.
    • (2007) Leuk Lymphoma , vol.48 , pp. 1003-1014
    • Ying, S.X.1
  • 26
    • 0029583080 scopus 로고
    • Myeloid progenitor cell regulatory effects of vascular endothelial cell growth factor
    • Broxmeyer HE, et al. (1995) Myeloid progenitor cell regulatory effects of vascular endothelial cell growth factor. Int J Hematol 62:203-215.
    • (1995) Int J Hematol , vol.62 , pp. 203-215
    • Broxmeyer, H.E.1
  • 27
    • 0026503847 scopus 로고
    • Identification of a novel gene expressed in activated natural killer cells and T cells
    • Dahl CA, Schall RP, He HL, Cairns JS (1992) Identification of a novel gene expressed in activated natural killer cells and T cells. J Immunol 148:597-603.
    • (1992) J Immunol , vol.148 , pp. 597-603
    • Dahl, C.A.1    Schall, R.P.2    He, H.L.3    Cairns, J.S.4
  • 28
    • 33644538600 scopus 로고    scopus 로고
    • Cytolytic function and survival of natural killer cells are severely altered in myelodysplastic syndromes
    • Kiladjian JJ, et al. (2006) Cytolytic function and survival of natural killer cells are severely altered in myelodysplastic syndromes. Leukemia 20:463-470.
    • (2006) Leukemia , vol.20 , pp. 463-470
    • Kiladjian, J.J.1
  • 29
    • 0031740061 scopus 로고    scopus 로고
    • Tumor necrosis factor-alpha levels decrease with anticytokine therapy in patients with myelodysplastic syndromes
    • Reza S, Shetty V, Dar S, Qawi H, Raza A (1998) Tumor necrosis factor-alpha levels decrease with anticytokine therapy in patients with myelodysplastic syndromes. J Interferon Cytokine Res 18:871-877.
    • (1998) J Interferon Cytokine Res , vol.18 , pp. 871-877
    • Reza, S.1    Shetty, V.2    Dar, S.3    Qawi, H.4    Raza, A.5
  • 30
    • 0036738149 scopus 로고    scopus 로고
    • Stromal cells prevent apoptosis of AML cells by upregulation of anti-apoptotic proteins
    • Konopleva M, et al. (2002) Stromal cells prevent apoptosis of AML cells by upregulation of anti-apoptotic proteins. Leukemia 16:1713-1724.
    • (2002) Leukemia , vol.16 , pp. 1713-1724
    • Konopleva, M.1
  • 31
    • 0035066012 scopus 로고    scopus 로고
    • Acute myeloid leukemia cells are protected from spontaneous and drug-induced apoptosis by direct contact with a human bone marrow stromal cell line (HS-5)
    • Garrido SM, Appelbaum FR, Willman CL, Banker DE (2001) Acute myeloid leukemia cells are protected from spontaneous and drug-induced apoptosis by direct contact with a human bone marrow stromal cell line (HS-5). Exp Hematol 29:448-457.
    • (2001) Exp Hematol , vol.29 , pp. 448-457
    • Garrido, S.M.1    Appelbaum, F.R.2    Willman, C.L.3    Banker, D.E.4
  • 32
    • 34748926429 scopus 로고    scopus 로고
    • Stromal-cell regulation of natural killer cell differentiation
    • DOI:10.1007/s00109-007-0195-0
    • Roth C, Rothlin C, Riou S, Raulet DH, Lemke G. (2007) Stromal-cell regulation of natural killer cell differentiation. J Mol Med DOI:10.1007/s00109-007-0195-0.
    • (2007) J Mol Med
    • Roth, C.1    Rothlin, C.2    Riou, S.3    Raulet, D.H.4    Lemke, G.5
  • 33
    • 0028963195 scopus 로고
    • Functionally distinct human marrow stromal cell lines immortalized by transduction with the human papilloma virus E6/E7 genes
    • Roecklein BA, Torok-Storb B (1995) Functionally distinct human marrow stromal cell lines immortalized by transduction with the human papilloma virus E6/E7 genes. Blood 85:997-1005.
    • (1995) Blood , vol.85 , pp. 997-1005
    • Roecklein, B.A.1    Torok-Storb, B.2
  • 34
    • 0018940849 scopus 로고
    • An undifferentiated variant derived from the human acute myelogenous leukemia cell line (KG-1)
    • Koeffler HP, Billing R, Lusis AJ, Sparkes R, Golde DW (1980) An undifferentiated variant derived from the human acute myelogenous leukemia cell line (KG-1). Blood 56:265-273.
    • (1980) Blood , vol.56 , pp. 265-273
    • Koeffler, H.P.1    Billing, R.2    Lusis, A.J.3    Sparkes, R.4    Golde, D.W.5
  • 35
    • 0034769641 scopus 로고    scopus 로고
    • Comparison of gene expression in CD34+ cells from bone marrow and G-CSF mobilized peripheral blood by high-density oligonucleotide array analysis
    • Graf L, Heimfeld S, Torok-Storb B (2001) Comparison of gene expression in CD34+ cells from bone marrow and G-CSF mobilized peripheral blood by high-density oligonucleotide array analysis. Biol Blood Marrow Transplant 7:486-494.
    • (2001) Biol Blood Marrow Transplant , vol.7 , pp. 486-494
    • Graf, L.1    Heimfeld, S.2    Torok-Storb, B.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.