Deletion of microRNA-80 Activates Dietary Restriction to Extend C. elegans Healthspan and Lifespan

PLoS Genetics

Volumn 9, Issue 8, 2013, Pages

  Vora, Mehul ^a   Shah, Mitalie ^a   Ostafi, Silvana ^a   Onken, Brian ^a   Xue, Jian ^a   Ni, Julie Zhouli ^a   Gu, Sam ^a   Driscoll, Monica ^a  

^a RUTGERS UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN BINDING PROTEIN; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN BINDING PROTEIN 1; HEAT SHOCK TRANSCRIPTION FACTOR 1; LIPOFUSCIN; METFORMIN; MICRORNA; MICRORNA 80; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR DAF 16; TRANSCRIPTION FACTOR FOXO; TRANSCRIPTION FACTOR SKN 1; UNCLASSIFIED DRUG;

5' UNTRANSLATED REGION; AGING; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BINDING SITE; BIOACCUMULATION; CAENORHABDITIS ELEGANS; CBP 1 GENE; COMPUTER MODEL; CONTROLLED STUDY; DAF 16 GENE; DIET RESTRICTION; DOWN REGULATION; DRUG SENSITIVITY; FERTILITY; FOXO GENE; GENE; GENE DELETION; GENE EXPRESSION REGULATION; GENE IDENTIFICATION; GENE INACTIVATION; GENE TARGETING; GENETIC CONSERVATION; HEART FUNCTION; HSF 1 GENE; LIFE EXTENSION; LONGEVITY; METABOLIC ACTIVATION; MUSCLE FUNCTION; NONHUMAN; PHENOTYPE; PROTEIN EXPRESSION; RNA INTERFERENCE; SURVIVAL RATE; TRANSCRIPTION REGULATION;

ANIMALS; CAENORHABDITIS ELEGANS; CAENORHABDITIS ELEGANS PROTEINS; CALORIC RESTRICTION; GENE EXPRESSION REGULATION; HISTONE ACETYLTRANSFERASES; LONGEVITY; MICRORNAS; SEQUENCE DELETION; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS;

EID: 84884661996     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1003737     Document Type: Article

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