A CBP/p300 homolog specifies multiple differentiation pathways in Caenorhabditis elegans

Genes and Development

Volumn 12, Issue 7, 1998, Pages 943-955

  Shi, Yang ^a   Mello, Craig ^b  

^a HARVARD MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

Author keywords

C. elegans; CBP 1; Differentiation; HDA 1; HDAC1; Histone acetyltransferase; Histone diacetylase; p300

Indexed keywords

HISTONE ACETYLTRANSFERASE; TRANSCRIPTION FACTOR;

ARTICLE; CAENORHABDITIS ELEGANS; CELL DIFFERENTIATION; CELL GROWTH; EMBRYO DEVELOPMENT; ENZYME ACTIVITY; GROWTH REGULATION; NONHUMAN; PRIORITY JOURNAL;

ADENOVIRIDAE; CAENORHABDITIS ELEGANS; INVERTEBRATA; MAMMALIA;

EID: 0032053770     PISSN: 08909369     EISSN: None     Source Type: Journal    
DOI: 10.1101/gad.12.7.943     Document Type: Article

References (88)

1. Akimaru, H., Y. Chen, P. Dai, D.-X. Hou, M. Nonaka, S.M. Smolik, S. Armstrong, R.H. Goodman, and I. Shunsuke. 1997. Drosophila CBP is a co-activator of cubitus interruptus in hedgehog signalling. Nature 386: 735-738.
2. Alland, L, R. Muhle, H.J. Hou, J. Potes, L. Chin, N. Schreiberagus, and R.A. DePinho. 1997. Role for N-CoR and histone deacetylase in Sin3-mediated transcriptional repression. Nature 387: 49-55.
3. Arany, Z., W.R. Sellers, D.M. Livingston, and R. Eckner. 1994. E1A-associated p300 and CREB-associated CBP belong to a conserved family of coactivators. Cell 77: 799-800.
4. Arias, J., A.S. Alberts, P. Brindle, F.X. Claret, T. Smeal, M. Karin, J. Feramisco, and M. Montminy. 1994. Activation of cAMP and mitogen responsive genes relies on a common nuclear factor. Nature 370: 226-229.
5. Bannister, A.J. and T. Kouzarides. 1996. The CBP co-activator is a histone acetyltransferase. Nature 384: 641-643.
6. Blackwell, T.K., B. Bowerman, J.R. Priess, and H. Weintraub. 1994. Formation of a monomeric DNA binding domain by Skn-1 hZIP and homeodomain elements. Science 266: 621-628.
7. Bowerman, B., B.A. Eaton, and J.R. Priess. 1992a. skn-1, a maternally expressed gene required to specify the fate of ventral blastomeres in the early C. elegans embryo. Cell 68: 1061-1075.
8. Bowerman, B., F.E. Tax, J.H. Thomas, and J.R. Priess. 1992b. Cell interactions involved in development of the bilaterally symmetrical intestinal valve cells during embryogenesis in Caenorhabditls elegans. Development 116: 1113-1122.
9. Bowerman, B., B.W. Draper, C.C. Mello, and J.R. Priess. 1993. The maternal gene skn-1 encodes a protein that is distributed unequally in early c. elegans embryos. Cell 74: 443-452.
10. Brownell, J.E. and C.D. Allis. 1996. Special HATs for special occasions: linking histone acetylation to chromatin assembly and gene activation. Curr. Opin. Genet. &. Dev. 6: 176-184.
11. Chen, H., R.J. Lin, R.L. Schiltz, D. Chakravarti, A. Nash, L. Nagy, M.L. Privalsky, Y. Nakatani, and R.M. Evans. 1997. Nuclear receptor coactivator ACTR is a novel histone acetyltransferase and forms a multimeric activation complex with P/CAF and CBP/p300. Cell 90: 569-580.
12. Chrivia, J.C., R.P.S. Kwok, N. Lamb, M. Hagiwara, M.R. Montimy, and R.H. Goodman. 1993. Phosphorylated CREB binds specifically to the nuclear protein CBP. Nature 265: 855-859.
13. Eckner, R. 1996. p300 and CBP as transcriptional regulators and targets of oncogenic events. Biol. Chem. 377: 685-688.
14. Eckner, R., M.E. Ewen, D. Newsome, M. Gerdes, J.A. DeCaprio, J.B. Lawrence, and D.M. Livingston. 1994. Molecular cloning and functional analysis of the adenovirus E1A-associated 300-kD protein (p300) reveals a protein with properties of a transcriptional adaptor. Genes & Dev. 8: 869-884.
15. Eckner, R., T.-P. Yao, E. Oldread, and D.M. Livingston. 1996. Interaction and functional collaboration of p300/CBP and bHLH proteins in muscle and B-cell differentiation. Genes & Dev. 10: 2478-2490.
16. Finney, M. and G. Ruvkun. 1990. The unc-86 gene product couples cell lineage and cell identity in C. elegans. Call 63: 895-905.
17. Fire, A., S. Xu, M.K. Montgomery, S. Kostas, S.E. Driver, and C.C. Mello. 1998. Potent and specific genetic interference in C. elegans mediated by double stranded RNA. Nature 391: 806-810.
18. Goldman, P.S., V.K. Tran, and R.H. Goodman. 1997. The multifunctional role of the co-activator CBP in transcriptional regulation. Recent Prog. Hormone Res. 52: 103-119.
19. Grunstein, M. 1997. Histone acetylation in chromatin structure and transcription. Nature 389: 349-352.
20. Gu, W. and R.G. Roeder. 1997. Activation of p53 sequence-specific DNA binding by acetylation of the p53 C-terminal domain. Cell 90: 595-606.
21. Guedes, S. and J.R. Priess. 1997. The C. elegans MEX-1 protein is present in germline blastomeres and is a P granule component. Development 124: 731-739.
22. Guo, S. and K.J. Kumphues. 1995. par-1, a gene required for establishing polarity in C. elegans embryos, encodes a putative Ser/Thr kinase that is asymmetrically distributed. Cell 81: 611-620.
23. _. 1996. A non-muscle myosin required for embryonic polarity in Caenorhabditis elegans. Nature 382: 455-458.
24. Hamelin, M., I.M. Scott, J.C. Way, and J.G. Culotti. 1992. The mec-7 beta-tubulin gene of Caenorhabditis elegans is expressed premarily in the touch receptor neurons. EMBO J. 11: 2885-2893.
25. Harlow, E., P. Whyte, B.R. Franza Jr., and C. Schely. 1986. Association of adenovirus early region 1A proteins with cellular polypeptides. Mol Cell. Biol. 6: 1579-1589.
26. Hassig, C.A., T.C. Fleischer, A.N. Billin, S.L. Schreiber, and D.E. Ayer. 1997. Histone deacetylase activity is required for full transcriptional repression by mSin3A. Cell 89: 341-347.
27. Heinzel, T., R.M. Lavinsky, T.M, Mullen, M. Soderstrom, C.D. Laherty, J. Torchia, W.M. Yang, G. Brard, S.D. Ngo, J.R. Davie, E. Seto, R.N. Eisenman, D.W. Rose, C.K. Glass, and M.G. Rosenfeld. 1997. A complex containing N-CoR, mSin3 and histone deacetylase mediates transcriptional repression. Nature 387: 43-48.
28. Hemmati-Brivanlou, A. and D. Melton. 1997. Vertebrate embryonic cells will become nerve cells unless told otherwise. Cell 88: 13-17.
29. Hunter, C.P. and C. Kenyon. 1996. Spatial and temporal controls target pal-1 blastomere-specification activity to a single blastomere lineage in C. elegans embryos. Cell 87: 217-226.
30. Imhof, A., X.-J. Yang, V.V. Ogryzko, Y. Nakatani, A.P. Wolffe, and H. Ge. 1997. Acetylation of general transcription factors by histone acetyltransferases. Curr. Biol. 7: 689-692.
31. Janknecht, R. and T. Hunter. 1996. Transcriptional control: Versatile molecular glue. Curr. Biol. 6: 951-954.
32. Kadosh, D. and K. Struhl. 1997. Repression by Ume6 involves recruitment of a complex containing Sin3 corepressor and Rpd3 histone deacetylase to target promoters. Cell 89: 365-371.
33. _. 1998. Histone deacetylase activity of Rpd3 is important for transcriptional repression in vivo. Genes & Dev. (in press).
34. Kamakaka, R.T., P.D. Kaufman, B. Stillman, P.G. Mitsis, and J.T. Kadonaga. 1996. Postreplicative chromatin assembly by Drosophila and human chromatin assembly factor 1. Mol. Cell. Biol. 16: 810-817.
35. Kawasaki, H., J. Song, R. Eckner, H. Ugai, R. Chiu, K. Raira, Y. Shi, N. Jones, and K.K. Yokoyama. 1998. p300 and ATF-2 are components of the DRF complex that regulates the retinoic acid- and E1A-mediated transcription of the c-jun gene in F9 cells. Genes & Dev. 12: 233-245.
36. Kirshenbaum, L. and M.D. Schneider. 1995. Adenovirus E1A represses cardiac gene transcription and reactivates DNA synthesis in ventricular myocytes, via alternative pocket protein- and p300-binding domains. J. Biol. Chem. 270: 7791-7794.
37. Krause, M.W., A. Fire, S.W. Harrision, J. Priess, and H. Weintraub. 1990. CeMyoD accumulation defines the bodywall muscle cell fate during C. elegans embryogenesis. Cell 63: 907-922.
38. Krause, M., M. Park, J.-M. Zhang, J. Yuan, B. Harfe, S.-Q. Xu, I. Greenwald, M. Cole, B. Paterson, and A. Fire. 1997. A C. elegans E/Daughterliss bHLH protein is present during neuronal but not striated muscle development. Development 124: 2179-2189.
39. Kwok, R.P.S., J.R. Lundblad, J.C. Chrivia, J.P. Richards, H.P. Bachinger, R.G. Brennan, S.G.E. Roberts, M.R. Green, and R.H. Goodman. 1994. Nuclear protein CBP is a coactivator for the transcription factor CREB. Nature 370: 223-226.
40. Laherty, C.D., W.M. Yang, J.M. Sun, J.R. Davie, E. Seto, and R.N. Eisenman. 1997. Histone deacetylases associated with the mSIN3 corepressor mediate mad transcriptional repression. Cell 89: 349-356.
41. Lee, J.-S., X.-L. Zhang, and Y. Shi. 1996. Differential interactions of the CREB/ATF family of transcription factors with p300 and adenovirus E1A. J. Biol. Chem. 271: 17666-17674.
42. Lin, R., S. Thompson, and J.R. Priess. 1995. pop-1 encodes an HMG box protein required for the specification of a mesoderm precursor in early C. elegans embryos. Cell 83: 599-609.
43. Lundblad, J.R., R.P.S. Kwok, M.E. Laurance, M.L. Harter, and R.H. Goodman. 1995. Adenoviral E1A-associated protein p300 as a functional homologue of the transcriptional coactivator CBP. Nature 374: 85-88.
44. Martinez-Balbas, M.A., T. Tsukiyma, D. Gdula, and C. Wu. 1998. Drosophila NURF-55, a WD repeat protein involved in histone metabolism. Proc. Natl. Acad. Sci. 95: 132-137.
45. Mello, C.C., J.M. Kramer, D. Stinchcomb, and V. Ambros. 1991. Efficient gene transfer in C. elegans: Extrachromosomal maintenance and integration of transforming sequences. EMBO J. 10: 3959-3970.
46. Mello, C.C., C. Schubert, B. Draper, W. Zhang, B. Lobel, and J.R. Priess. 1992. The pie-1 and mex-1 genes and maternal control of blastomere identity in early C. elegans embryos. Cell 70: 163-176.
47. Mello, C.C., C. Schubert, B. Draper, W. Zhang, R. Lobel, and J.R. Priess. 1996. The PIE-1 protein and germline specification in C. elegans embryos. Nature 382: 710-712.
48. Miller, D.M., III, I. Oritz, G.C. Berliner, and H.F. Epstein. 1983. Differential localization of two myosins within nematode thick filaments. Cell 34: 477-490.
49. Muraoka, M., M. Konishi, R. Kikuchi-Yanoshita, K. Tanaka, N. Shitara, J.-M. Chong, T. Iwama, and M. Miyaki. 1996. p300 gene alterations in colorectal and gastric carcinoma. Oncogene 12: 1565-1569.
50. 3H1 myoblasts correlates with their binding to a 300 kDa cellular protein. Mol. Biol. Cell 3: 1107-1115.
51. Nagy, L., H.Y. Kao, D. Chakravarti, R.J. Lin, C.A. Hassig, D.E. Ayer, S.L. Schreiber, and R.M. Evans. 1997. Nuclear receptor repression mediated by a complex containing SMRT, mSin3A, and histone deacetylase. Cell 89: 373-380.
52. Nakajima, T., C. Uchida, S.F. Adderson, J.D. Parvin, and M. Montminy. 1997a. Analysis of cAMP-responsive activator reveals a two-component mechanism for transcriptional induction via signal-dependent factors. Genes & Dev. 11: 738.
53. Nakajima, T., C. Uchida, S.F. Anderson, C.-G. Lee, J. Hurwitz, J.D. Parvin, and M. Montminy. 1997b. RNA helicase A mediates association of CBP with RNA polymerase II. Cell 90: 1107-1112.
54. Nasmyth, K., D. Stillman, and D. Kipling. 1987. Both positive and negative regulators of HO transcription are required for mother-cell-specific mating-type switch in yeast. Cell 48: 579-587.
55. Ogryzko, V., R.L. Schiltz, V. Russanova, B.H. Howard, and Y. Nakatani. 1996. The transcriptional coactivator p300 and CBP are histone acetyltransferases. Cell 87: 953-959.
56. Parker, D., K. Ferrei, T. Nakajima, V.J. LaMorte, R. Evans, S.C. Koerber, C. Hoeger, and M.R. Montiminy. 1996. Phosphorylation of CREB at Ser-133 induces complex formation with CREb-binding protein via a direct mechanism. Mol. Cell. Biol. 16: 694-703.
57. Pazin, M.J. and J.T. Kadonaga. 1997. What is up and down with histone deacetylation and transcription? Cell 89: 325-328.
58. Powell-Coffman, J.A., J. Knight, and W.B. Wood. 1996. Onset of C. elegans gastrulation is blocked by inhibition of embryonic transcription with an RNA polymerase antisense RNA. Dev. Biol. 178: 472-483.
59. Priess, J.R. and J.N. Thomson. 1987. Cellular interactions in early C. elegans embryos. Cell 48: 241-250.
60. Puri, P.L., M.L. Avantaggiati, C. Balsano, N. Sang, A. Graessmann, A. Giordano, and M. Levrero. 1997. p300 is required for MyoD-dependent cell cycle arrest and muscle-specific gene transcription. EMBO J. 16: 369-383.
61. Qian, Y.-W. and E.Y.-H.P. Lee. 1995. Dual retinoblastoma-binding proteins with properties related to a negative regulator of ras in yeast. J. Biol Chem. 270: 25507-25513.
62. Qian, Y.-W., Y.-C.J. Wang, R.E. Hollingsworth Jr., D. Jones, N. Ling, and E.Y.-H. Lee. 1993. A retinoblastoma-binding protein related to a negative regulator of Ras in yeast. Nature 364: 648-652.
63. Rocheleau, C., W.D. Downs, R.L. Lin, C. Wittman, Y.X. Bei, M. Ali, J.R. Priess, and C.C. Mello. 1997. Wnt signaling and an APC related gene specify endoderm in early C. elegans. Cell 90: 707-716.
64. Roth, S.Y. 1996. Something about silencing.Nature Genetics 14: 3-4.
65. Ruley, H.E. 1983. Adenovirus early region 1A enables viral and cellular transforming genes to transform primary cells in culture. Nature 304: 602-606.
66. Rundlett, S.E., A.A. Carmen, R. Kobayashi, S. Bavykin, B.M. Turner, and M. Grunstein. 1996. HDA1 and RPD3 are members of distinct yeast histone deacetylase complexes that regulate silencing and transcription. Proc. Natl. Acad. Sci. 93: 14503-14508.
67. Schnabel, R. and J.R. Priess, 1997. Specification of cell fates in the early embryo. In C. elegans (ed. D.L. Riddle, T. Blumenthal, B.J. Meyer, and J.R. Preiss), pp. 361-382. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
68. Seydoux, G., C.C. Mello, J. Pettitt, W.B. Wood, J.R. Priess, and A. Fire. 1996. Repression of gene expression in the embryonic germ lineage of C. elegans. Nature 382: 713-716.
69. Shikama, N., J. Lyon, and N.B. Lathangue. 1997. The p300/CBP family-integrating signals with transcription factors and chromatin. Trends Cell. Biol. 7: 230-236.
70. Smith, S. and B.W. Stillman. 1989. Purification and characterization of CAF-1, a human cell factor required for chromatin assembly during DNA replication in vitro. Cell 58: 15-25.
71. Smits, P.H.M., L. de Wit, A.J. vander Eb, and A. Zantema. 1996. The adenovirus E1A-associated p300 kDa adaptor protein counteracts the inhibition of the collagenase promoter by E1A and represses transformation. Oncogene 12: 1529-1535.
72. Stillman, D.J., S. Dorland, and Y. Yu. 1994. Epistasis analysis of suppressor mutations that allow HO expression in the absence of the yeast SW15 transcriptional activator. Genetics 136: 781-788.
73. Strome, S. and W.B. Wood. 1982. Immunofluorescence visualization of germ-line-specific cytoplasmic granules in embryos, larvae, and adults of C. elegans. Proc. Natl. Acad. Sci. 79: 15-29.
74. Swope, D.L, C.L. Mueller, and J.C. Chrivia. 1996. CREB-binding protein activates transcription through multiple domains. J. Biol. Chem. 271:28138-28145.
75. Taunton, J., C.A. Hassig, and S.L. Schreiber. 1996. A mammalian histone deacetylase related to the yeast transcriptional regulator Rpd3p. Science 272: 408-411.
76. Thorpe, C.J., A. Schlesinger, J.C. Carter, and B. Bowerman. 1997. Wnt signaling polarizes an eaerly C. elegans blastomere to distinguish endoderm and mesoderm. Cell 90: 695-705.
77. Tyler, J.K., M. Bulger, R.T. Kamakaka, R. Kobayashi, and J.T. Kadonaga. 1996. The p55 subunit of Drosophila chromatin assembly factor 1 is homologous to a histone deacetylase-associated protein. Mol. Cell. Biol. 16:6149-6159.
78. van der Elsen, P., S. de Parter, A. Houweling, J. van der Veer, and A.J. van der Eb. 1982. The relationship between regions E1a and E1b of human adenoviruses in cell transformation. Gene 18: 175-185.
79. van der Elsen, P.J., A. Houweling, and A.J. van der Eb. 1983. Morphological transformation of human adenoviruses is determined to a large extent by gene products of region E1a. Virology 131: 242-246.
80. Vidal, M. and R.F. Gaber. 1991. RPD3 encodes a second factor required to achieve maximun positive and negative transcriptional states in Saccharomyces cerevisiae. Mol. Cell. Biol 11: 6317-6327.
81. Vidal, M., A.M. Buckley, F. Hilger, and R.F. Gaber. 1990. Direct selection for mutants with increased K+ transport in Saccharomyces cerevisiae. Genetics 125: 313-320.
82. Wade, P.A. and A.P. Wolffe. 1997. Histone acetyltransferases in control. Curr. Biol. 7: R82-84.
83. Wang, H.G., E. Moran, and P. Yaciuk. 1995. E1A promotes association between p300 and pRB in multimeric complexes required for normal biological activity. J Virol. 69: 7917-7924.
84. Whyte, P., N.M. Williamson, and E. Harlow. 1989. Cellular targets for transformation by the adenovirus E1A proteins. Cell 56: 67-75.
85. Wolffe, A.P. 1996. Histone deacetylase: A regulator of transcription. Science 272: 371-372.
86. Yang, W.-M., C. Inouye, Y. Zeng, D. Bearss, and E. Seto. 1996. Transcriptional repression by YY1 is mediated by interaction with a mammalian homolog of the yeast global regulator RPD3. Proc. Natl. Acad. Sci. 93: 12845-12850.
87. Yang, X.-J., V.V. Ogryzko, J.-I. Nishikawa, B.H. Howard, and Y. Nakatani. 1996. A p300/CBP-associated factor that competes with the adenovirial oncoprotein E1A. Nature 382: 319-324.
88. Yee, S.P. and P.E. Branton. 1985. Detection of cellular proteins associated with human adenovirus type 5 early region 1A polypeptides. Virology 147: 142-153.