The antiviral lectin cyanovirin-N: Probing multivalency and glycan recognition through experimental and computational approaches

Biochemical Society Transactions

Volumn 41, Issue 5, 2013, Pages 1170-1176

  Woodrum, Brian W ^a   Maxwell, Jason D ^a   Bolia, Ashini ^a   Banu Ozkan, S ^a   Ghirlanda, Giovanna ^a  

^a ARIZONA STATE UNIVERSITY   (United States)

Author keywords

Antiviral lectin; Cyanovirin; Glycoprotein 120 (gp120); Multivalency; Perturbation response scanning; Protein glycan interaction

Indexed keywords

ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT; ANTIVIRUS AGENT; CARBOHYDRATE BINDING PROTEIN; CYANOVIRIN N; DIMER; GLYCAN; GLYCOPROTEIN GP 120; GLYCOSYLATED PROTEIN; LECTIN; MANNOSE OLIGOSACCHARIDE; MANNOSIDE;

ANTIVIRAL ACTIVITY; ARTICLE; BINDING AFFINITY; CRYSTAL STRUCTURE; CYANOBACTERIUM; DRUG PROTEIN BINDING; DRUG STRUCTURE; ENZYME LINKED IMMUNOSORBENT ASSAY; LECTIN BINDING SITE; MUTAGENESIS; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN GLYCOSYLATION; PROTEIN PROTEIN INTERACTION; SEQUENCE ANALYSIS; VIRUS ENTRY; VIRUS INHIBITION;

AMINO ACID SEQUENCE; ANTI-HIV AGENTS; BACTERIAL PROTEINS; BINDING SITES; CARRIER PROTEINS; CYANOBACTERIA; HIV; HIV ENVELOPE PROTEIN GP120; HIV INFECTIONS; HUMANS; LECTINS; POLYSACCHARIDES; PROTEIN BINDING; PROTEIN CONFORMATION;

EID: 84884648529     PISSN: 03005127     EISSN: 14708752     Source Type: Journal    
DOI: 10.1042/BST20130154     Document Type: Article

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