Aldose reductase regulates acrolein-induced cytotoxicity in human small airway epithelial cells

Free Radical Biology and Medicine

Volumn 65, Issue , 2013, Pages 15-25

  Yadav, Umesh C S ^a   Ramana, K V ^a   Srivastava, Satish K ^a  

^a University of Texas Medical Branch School of Medicine   (United States)

Author keywords

Acrolein; Airway epithelial cells; Aldose reductase; Apoptosis; COPD; Cytotoxicity; Free radicals

Indexed keywords

ACROLEIN; ALDEHYDE REDUCTASE; CYTOCHROME C; FIDARESTAT; LIPOCORTIN 5; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN BAD; PROTEIN BAX; PROTEIN BCL 2; PROTEIN BCL XL; PROTEIN C JUN; REACTIVE OXYGEN METABOLITE; STRESS ACTIVATED PROTEIN KINASE; ENZYME INHIBITOR; IMIDAZOLIDINE DERIVATIVE; SMALL INTERFERING RNA;

APOPTOSIS; ARTICLE; CELL DEATH; CELL VIABILITY; CELLULAR DISTRIBUTION; CHROMATIN; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOSOL; CYTOTOXICITY; DNA DAMAGE; DNA FRAGMENTATION; DRUG EFFECT; ENZYME ACTIVATION; ENZYME INHIBITION; EPITHELIUM CELL; FLUORESCENCE; G2 PHASE CELL CYCLE CHECKPOINT; HUMAN; HUMAN CELL; MITOCHONDRION; POLYMERIZATION; PRIORITY JOURNAL; PROTEIN SECRETION; PROTEIN TRANSPORT; REGULATORY MECHANISM; RESPIRATORY EPITHELIUM; BRONCHUS; CELL CULTURE; COMET ASSAY; DRUG EFFECTS; ENZYMOLOGY; GENETIC TRANSFECTION; METABOLISM; RESPIRATORY TRACT MUCOSA; WESTERN BLOTTING;

ACROLEIN; ALDEHYDE REDUCTASE; APOPTOSIS; BLOTTING, WESTERN; BRONCHI; CELLS, CULTURED; COMET ASSAY; DNA DAMAGE; ENZYME INHIBITORS; HUMANS; IMIDAZOLIDINES; REACTIVE OXYGEN SPECIES; RESPIRATORY MUCOSA; RNA, SMALL INTERFERING; TRANSFECTION;

EID: 84884574846     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2013.06.008     Document Type: Article

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