Berberine exerts nephroprotective effect against cisplatin-induced kidney damage through inhibition of oxidative/nitrosative stress, inflammation, autophagy and apoptosis

Food and Chemical Toxicology

Volumn 62, Issue , 2013, Pages 397-406

  Domitrović, Robert ^a   Cvijanović, Olga ^a   Pernjak Pugel, Ester ^a   Škoda, Marko ^a   Mikelić, Lorena ^a   Crnčević Orlić, Željka ^b  

^a UNIVERSITY OF RIJEKA   (Croatia)

^b KBC RIJEKA   (Croatia)

Author keywords

Apoptosis; Autophagy; Berberine; Cisplatin nephrotoxicity; Inflammatory response; Oxidative stress

Indexed keywords

3 NITROTYROSINE; 4 HYDROXYNONENAL; BERBERINE; CASPASE 3; CISPLATIN; CYCLOOXYGENASE 2; CYTOCHROME P450 2E1; HEME OXYGENASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; NITRIC OXIDE SYNTHASE; PROTEIN P53; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; AUTOPHAGY; CONTROLLED STUDY; CREATININE BLOOD LEVEL; DRUG DOSE COMPARISON; DRUG EFFECT; ENZYME INHIBITION; ENZYME REPRESSION; INFLAMMATION; KIDNEY INJURY; MALE; MOUSE; NEPHROTOXICITY; NITROSATIVE STRESS; NONHUMAN; OXIDATIVE STRESS; PROTEIN SYNTHESIS INHIBITION; RENAL PROTECTION; UREA NITROGEN BLOOD LEVEL;

ANIMALIA; MUS;

3-NITROTYROSINE; 3-NT; 4-HNE; 4-HYDROXYNONENAL; APOPTOSIS; AUTOPHAGY; BERBERINE; BLOOD UREA NITROGEN; BUN; CIS-DIAMINEPLATINUM(II) DICHLORIDE; CISPLATIN NEPHROTOXICITY; COX-2; CP; CYCLOOXYGENASE-2; CYP2E1; CYTOCHROME P450 2E1; DIMETHYL SULFOXIDE; DMSO; FITC; FLUORESCEIN ISOTHIOCYANATE; HE; HEMATOXYLIN AND EOSIN; HEME OXYGENASE-1; HO-1; IL; INDUCIBLE NITRIC OXIDE SYNTHASE; INFLAMMATORY RESPONSE; INOS; INTERLEUKIN; LC3; LIGHT CHAIN 3B; NF-ΚB; NITRIC OXIDE; NO(); NUCLEAR FACTOR-KAPPAB; OXIDATIVE STRESS; PAS; PERIODIC ACID-SCHIFF; POLYVINYLIDENE DIFLUORIDE; PVDF; RADIOIMMUNOPRECIPITATION ASSAY; RIPA; TERMINAL DEOXYNUCLEOTIDYL TRANSFERASE DUTP NICK END LABELING; TNF-Α; TUMOR NECROSIS FACTOR-ALPHA; TUNEL;

ALDEHYDES; ANIMALS; APOPTOSIS; AUTOPHAGY; BERBERINE; BLOOD UREA NITROGEN; CISPLATIN; CREATININE; CYTOCHROME P-450 CYP2E1; KIDNEY; MALE; MICE; MICE, INBRED BALB C; NEPHRITIS; OXIDATIVE STRESS; PROTECTIVE AGENTS; TYROSINE;

EID: 84884554622     PISSN: 02786915     EISSN: 18736351     Source Type: Journal    
DOI: 10.1016/j.fct.2013.09.003     Document Type: Article

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