Carnosic acid attenuates renal injury in an experimental model of rat cisplatin-induced nephrotoxicity

Food and Chemical Toxicology

Volumn 49, Issue 12, 2011, Pages 3090-3097

  Sahu, Bidya Dhar ^a   Rentam, Kiran Kumar Reddy ^b   Putcha, Uday Kumar ^c   Kuncha, Madhusudana ^b   Vegi, Ganga Modi Naidu ^d   Sistla, Ramakrishna ^b  

^a NATIONAL INSTITUTE OF PHARMACEUTICAL EDUCATION AND RESEARCH NIPER   (India)

^b INDIAN INSTITUTE OF CHEMICAL TECHNOLOGY   (India)

^c NATIONAL INSTITUTE OF NUTRITION   (India)

^d NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

Apoptosis; Carnosic acid; Cisplatin; Free radicals; Nephrotoxicity

Indexed keywords

CARNOSIC ACID; CASPASE 3; CATALASE; CREATININE; GLUTATHIONE; GLUTATHIONE PEROXIDASE; GLUTATHIONE REDUCTASE; GLUTATHIONE TRANSFERASE; MALONALDEHYDE; NITRITE; NITROGEN; REACTIVE OXYGEN METABOLITE; SUPEROXIDE DISMUTASE; UREA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; CONTROLLED STUDY; CREATININE BLOOD LEVEL; DRUG MECHANISM; ENZYME ACTIVITY; FEMALE; HISTOPATHOLOGY; KIDNEY DYSFUNCTION; KIDNEY MASS; LIPID PEROXIDATION; NEPHROTOXICITY; NONHUMAN; OXIDATIVE STRESS; RAT; RENAL PROTECTION; TISSUE LEVEL; UREA NITROGEN BLOOD LEVEL;

ACUTE KIDNEY INJURY; ANIMALS; ANTINEOPLASTIC AGENTS; ANTIOXIDANTS; APOPTOSIS; BLOOD UREA NITROGEN; CASPASE 3; CATALASE; CISPLATIN; CREATININE; DISEASE MODELS, ANIMAL; DITERPENES, ABIETANE; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; GLUTATHIONE; GLUTATHIONE PEROXIDASE; GLUTATHIONE REDUCTASE; GLUTATHIONE TRANSFERASE; KIDNEY; LIPID PEROXIDATION; MALONDIALDEHYDE; OXIDATIVE STRESS; PLANT EXTRACTS; RATS; RATS, WISTAR; REACTIVE OXYGEN SPECIES; SUPEROXIDE DISMUTASE;

RATTUS;

EID: 80054871000     PISSN: 02786915     EISSN: 18736351     Source Type: Journal    
DOI: 10.1016/j.fct.2011.08.018     Document Type: Article

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