Resolution of liver fibrosis by isoquinoline alkaloid berberine in CCl 4-intoxicated mice is mediated by suppression of oxidative stress and upregulation of MMP-2 expression

Journal of Medicinal Food

Volumn 16, Issue 6, 2013, Pages 518-528

  Domitrović, Robert ^a   Jakovac, Hrvoje ^a   Marchesi, Vanja Vasiljev ^a   Blažeković, Biljana ^b  

^a UNIVERSITY OF RIJEKA   (Croatia)

^b UNIVERSITY OF ZAGREB   (Croatia)

Author keywords

smooth muscle actin; Berberine; Factor 1; Liver fibrosis; Matrix metalloproteinases; Transforming growth; Tumor necrosis factor

Indexed keywords

ANTIFIBROTIC AGENT; BERBERINE; CARBON TETRACHLORIDE; COLLAGEN; GELATINASE A; ISOQUINOLINE ALKALOID; REACTIVE NITROGEN SPECIES; REACTIVE OXYGEN METABOLITE; SILYMARIN; TRANSFORMING GROWTH FACTOR BETA1; TUMOR NECROSIS FACTOR ALPHA;

AMINOTRANSFERASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; BIOACCUMULATION; CELL ACTIVATION; COLLAGEN DEGRADATION; CONTROLLED STUDY; DRUG EFFICACY; DRUG MECHANISM; DRUG MEGADOSE; ENZYME ACTIVATION; ENZYME ACTIVITY; IMMUNOHISTOCHEMISTRY; LIVER FIBROSIS; MALE; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; STELLATE CELL;

ANIMALS; BERBERINE; CARBON TETRACHLORIDE; HEPATIC STELLATE CELLS; HUMANS; ISOQUINOLINES; LIVER CIRRHOSIS; MALE; MATRIX METALLOPROTEINASE 2; MICE; MICE, INBRED BALB C; OXIDATIVE STRESS; TRANSFORMING GROWTH FACTOR BETA1; TUMOR NECROSIS FACTOR-ALPHA; UP-REGULATION;

MUS;

EID: 84879331156     PISSN: 1096620X     EISSN: 15577600     Source Type: Journal    
DOI: 10.1089/jmf.2012.0175     Document Type: Article

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