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Volumn 19, Issue 10, 2013, Pages 2041-2050

Colitis and colon cancer in WASP-deficient mice require helicobacter species

Author keywords

Animal models; Colitis; Helicobacter species; Inflammatory bowel disease; Wiskott Aldrich syndrome protein

Indexed keywords

WISKOTT ALDRICH SYNDROME PROTEIN;

EID: 84884541412     PISSN: 10780998     EISSN: 15364844     Source Type: Journal    
DOI: 10.1097/MIB.0b013e318295fd8f     Document Type: Article
Times cited : (31)

References (49)
  • 1
    • 0027937223 scopus 로고
    • Isolation of a novel gene mutated in Wiskott-Aldrich syndrome
    • Derry JM, Ochs HD, Francke U. Isolation of a novel gene mutated in Wiskott-Aldrich syndrome. Cell. 1994;78:635-644.
    • (1994) Cell. , vol.78 , pp. 635-644
    • Derry, J.M.1    Ochs, H.D.2    Francke, U.3
  • 2
    • 0037736679 scopus 로고    scopus 로고
    • Autoimmunity in Wiskott-Aldrich syndrome: Risk factors, clinical features, and outcome in a singlecenter cohort of 55 patients
    • Dupuis-Girod S, Medioni J, Haddad E, et al. Autoimmunity in Wiskott-Aldrich syndrome: risk factors, clinical features, and outcome in a singlecenter cohort of 55 patients. Pediatrics. 2003;111:e622-e627.
    • (2003) Pediatrics. , vol.111
    • Dupuis-Girod, S.1    Medioni, J.2    Haddad, E.3
  • 3
    • 0032118427 scopus 로고    scopus 로고
    • Wiskott-Aldrich syndrome protein-deficient mice reveal a role for WASP in T but not B cell activation
    • Snapper SB, Rosen FS, Mizoguchi E, et al. Wiskott-Aldrich syndrome protein-deficient mice reveal a role for WASP in T but not B cell activation. Immunity. 1998;9:81-90.
    • (1998) Immunity. , vol.9 , pp. 81-90
    • Snapper, S.B.1    Rosen, F.S.2    Mizoguchi, E.3
  • 4
    • 34848841804 scopus 로고    scopus 로고
    • Lymphocyte-dependent and Th2 cytokine-associated colitis in mice deficient in Wiskott-Aldrich syndrome protein
    • Nguyen DD, Maillard MH, Cotta-de-Almeida V, et al. Lymphocyte-dependent and Th2 cytokine-associated colitis in mice deficient in Wiskott-Aldrich syndrome protein. Gastroenterology. 2007;133:1188-1197.
    • (2007) Gastroenterology. , vol.133 , pp. 1188-1197
    • Nguyen, D.D.1    Maillard, M.H.2    Cotta-De-Almeida, V.3
  • 5
    • 33847161301 scopus 로고    scopus 로고
    • The Wiskott-Aldrich syndrome protein is required for the function of CD4(+)CD25 (+)Foxp3(+) regulatory T cells
    • Maillard MH, Cotta-de-Almeida V, Takeshima F, et al. The Wiskott-Aldrich syndrome protein is required for the function of CD4(+)CD25 (+)Foxp3(+) regulatory T cells. J Exp Med. 2007;204:381-391.
    • (2007) J Exp Med. , vol.204 , pp. 381-391
    • Maillard, M.H.1    Cotta-De-Almeida, V.2    Takeshima, F.3
  • 6
    • 33847168188 scopus 로고    scopus 로고
    • WASP regulates suppressor activity of human and murine CD4(+)CD25(+)FOXP3(+) natural regulatory T cells
    • Marangoni F, Trifari S, Scaramuzza S, et al. WASP regulates suppressor activity of human and murine CD4(+)CD25(+)FOXP3(+) natural regulatory T cells. J Exp Med. 2007;204:369-380.
    • (2007) J Exp Med. , vol.204 , pp. 369-380
    • Marangoni, F.1    Trifari, S.2    Scaramuzza, S.3
  • 7
    • 33846850600 scopus 로고    scopus 로고
    • Wiskott-Aldrich syndrome protein is required for regulatory T cell homeostasis
    • Humblet-Baron S, Sather B, Anover S, et al. Wiskott-Aldrich syndrome protein is required for regulatory T cell homeostasis. J Clin Invest. 2007; 117:407-418.
    • (2007) J Clin Invest. , vol.117 , pp. 407-418
    • Humblet-Baron, S.1    Sather, B.2    Anover, S.3
  • 8
    • 34250687456 scopus 로고    scopus 로고
    • Impaired in vitro regulatory T cell function associated with Wiskott-Aldrich syndrome
    • Adriani M, Aoki J, Horai R, et al. Impaired in vitro regulatory T cell function associated with Wiskott-Aldrich syndrome. Clin Immunol. 2007;124:41-48.
    • (2007) Clin Immunol. , vol.124 , pp. 41-48
    • Adriani, M.1    Aoki, J.2    Horai, R.3
  • 9
    • 68449092963 scopus 로고    scopus 로고
    • Wiskott-Aldrich syndrome: Immunodeficiency resulting from defective cell migration and impaired immunostimulatory activation
    • Bouma G, Burns SO, Thrasher AJ. Wiskott-Aldrich syndrome: immunodeficiency resulting from defective cell migration and impaired immunostimulatory activation. Immunobiology. 2009;214:778-790.
    • (2009) Immunobiology. , vol.214 , pp. 778-790
    • Bouma, G.1    Burns, S.O.2    Thrasher, A.J.3
  • 10
    • 55049111426 scopus 로고    scopus 로고
    • Sequence variants in IL10, ARPC2 and multiple other loci contribute to ulcerative colitis susceptibility
    • Franke A, Balschun T, Karlsen TH, et al. Sequence variants in IL10, ARPC2 and multiple other loci contribute to ulcerative colitis susceptibility. Nat Genet. 2008;40:1319-1323.
    • (2008) Nat Genet. , vol.40 , pp. 1319-1323
    • Franke, A.1    Balschun, T.2    Karlsen, T.H.3
  • 11
    • 77649153819 scopus 로고    scopus 로고
    • WASP: A key immunological multitasker
    • Thrasher AJ, Burns SO. WASP: a key immunological multitasker. Nat Rev Immunol. 2010;10:182-192.
    • (2010) Nat Rev Immunol. , vol.10 , pp. 182-192
    • Thrasher, A.J.1    Burns, S.O.2
  • 12
    • 61449190767 scopus 로고    scopus 로고
    • WASP confers selective advantage for specific hematopoietic cell populations and serves a unique role in marginal zone B-cell homeostasis and function
    • Westerberg LS, de la Fuente MA, Wermeling F, et al. WASP confers selective advantage for specific hematopoietic cell populations and serves a unique role in marginal zone B-cell homeostasis and function. Blood. 2008;112:4139-4147.
    • (2008) Blood. , vol.112 , pp. 4139-4147
    • Westerberg, L.S.1    De La Fuente, M.A.2    Wermeling, F.3
  • 13
    • 82655171771 scopus 로고    scopus 로고
    • Animal models of inflammatory bowel disease
    • Mizoguchi A. Animal models of inflammatory bowel disease. Prog Mol Biol Transl Sci. 2012;105:263-320.
    • (2012) Prog Mol Biol Transl Sci. , vol.105 , pp. 263-320
    • Mizoguchi, A.1
  • 14
    • 67649827195 scopus 로고    scopus 로고
    • Adaptive immunity in inflammatory bowel disease: State of the art
    • Kaser A, Blumberg RS. Adaptive immunity in inflammatory bowel disease: state of the art. Curr Opin Gastroenterol. 2008;24:455-461.
    • (2008) Curr Opin Gastroenterol. , vol.24 , pp. 455-461
    • Kaser, A.1    Blumberg, R.S.2
  • 15
    • 0032534043 scopus 로고    scopus 로고
    • A novel model of inflammatory bowel disease: Mice deficient for the multiple drug resistance gene, mdr1a, spontaneously develop colitis
    • Panwala CM, Jones JC, Viney JL. A novel model of inflammatory bowel disease: mice deficient for the multiple drug resistance gene, mdr1a, spontaneously develop colitis. J Immunol. 1998;161:5733-5744.
    • (1998) J Immunol. , vol.161 , pp. 5733-5744
    • Panwala, C.M.1    Jones, J.C.2    Viney, J.L.3
  • 16
    • 0033214528 scopus 로고    scopus 로고
    • Protection from radiation-induced colitis requires MHC class II antigen expression by cells of hemopoietic origin
    • Marguerat S, MacDonald HR, Kraehenbuhl JP, et al. Protection from radiation-induced colitis requires MHC class II antigen expression by cells of hemopoietic origin. J Immunol. 1999;163:4033-4040.
    • (1999) J Immunol. , vol.163 , pp. 4033-4040
    • Marguerat, S.1    MacDonald, H.R.2    Kraehenbuhl, J.P.3
  • 17
  • 18
    • 34848889673 scopus 로고    scopus 로고
    • Communicable ulcerative colitis induced by T-bet deficiency in the innate immune system
    • Garrett WS, Lord GM, Punit S, et al. Communicable ulcerative colitis induced by T-bet deficiency in the innate immune system. Cell. 2007;131:33-45.
    • (2007) Cell. , vol.131 , pp. 33-45
    • Garrett, W.S.1    Lord, G.M.2    Punit, S.3
  • 19
    • 77956569409 scopus 로고    scopus 로고
    • Enterobacteriaceae act in concert with the gut microbiota to induce spontaneous and maternally transmitted colitis
    • Garrett WS, Gallini CA, Yatsunenko T, et al. Enterobacteriaceae act in concert with the gut microbiota to induce spontaneous and maternally transmitted colitis. Cell Host Microbe. 2010;8:292-300.
    • (2010) Cell Host Microbe. , vol.8 , pp. 292-300
    • Garrett, W.S.1    Gallini, C.A.2    Yatsunenko, T.3
  • 20
    • 78149262230 scopus 로고    scopus 로고
    • Bifidobacterium animalis subsp. Lactis fermented milk product reduces inflammation by altering a niche for colitogenic microbes
    • Veiga P, Gallini CA, Beal C, et al. Bifidobacterium animalis subsp. lactis fermented milk product reduces inflammation by altering a niche for colitogenic microbes. Proc Natl Acad Sci U S A. 2010;107:18132-18137.
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 18132-18137
    • Veiga, P.1    Gallini, C.A.2    Beal, C.3
  • 21
    • 79956078164 scopus 로고    scopus 로고
    • Commensal bacteroides species induce colitis in host-genotype-specific fashion in a mouse model of inflammatory bowel disease
    • Bloom SM, Bijanki VN, Nava GM, et al. Commensal Bacteroides species induce colitis in host-genotype-specific fashion in a mouse model of inflammatory bowel disease. Cell Host Microbe 2011;9:390-403.
    • (2011) Cell Host Microbe , vol.9 , pp. 390-403
    • Bloom, S.M.1    Bijanki, V.N.2    Nava, G.M.3
  • 22
    • 34547645764 scopus 로고    scopus 로고
    • Enterohepatic helicobacter species are prevalent in mice from commercial and academic institutions in Asia, Europe, and North America
    • Taylor NS, Xu S, Nambiar P, et al. Enterohepatic Helicobacter species are prevalent in mice from commercial and academic institutions in Asia, Europe, and North America. J Clin Microbiol. 2007;45:2166-2172.
    • (2007) J Clin Microbiol. , vol.45 , pp. 2166-2172
    • Taylor, N.S.1    Xu, S.2    Nambiar, P.3
  • 23
    • 78650828652 scopus 로고    scopus 로고
    • Helicobacter hepaticus infection in mice: Models for understanding lower bowel inflammation and cancer
    • Fox JG, Ge Z, Whary MT, et al. Helicobacter hepaticus infection in mice: models for understanding lower bowel inflammation and cancer. Mucosal Immunol. 2011;4:22-30.
    • (2011) Mucosal Immunol. , vol.4 , pp. 22-30
    • Fox, J.G.1    Ge, Z.2    Whary, M.T.3
  • 24
    • 0028325311 scopus 로고
    • Helicobacter hepaticus sp. Nov., a microaerophilic bacterium isolated from livers and intestinal mucosal scrapings from mice
    • Fox JG, Dewhirst FE, Tully JG, et al. Helicobacter hepaticus sp. nov., a microaerophilic bacterium isolated from livers and intestinal mucosal scrapings from mice. J Clin Microbiol. 1994;32:1238-1245.
    • (1994) J Clin Microbiol. , vol.32 , pp. 1238-1245
    • Fox, J.G.1    Dewhirst, F.E.2    Tully, J.G.3
  • 25
    • 0028821062 scopus 로고
    • Helicobacter bilis sp. Nov., a novel Helicobacter species isolated from bile, livers, and intestines of aged, inbred mice
    • Fox JG, Yan LL, Dewhirst FE, et al. Helicobacter bilis sp. nov., a novel Helicobacter species isolated from bile, livers, and intestines of aged, inbred mice. J Clin Microbiol. 1995;33:445-454.
    • (1995) J Clin Microbiol. , vol.33 , pp. 445-454
    • Fox, J.G.1    Yan, L.L.2    Dewhirst, F.E.3
  • 26
    • 0023840221 scopus 로고
    • Case report of an unclassified microaerophilic bacterium associated with gastroenteritis
    • Romero S, Archer JR, Hamacher ME, et al. Case report of an unclassified microaerophilic bacterium associated with gastroenteritis. J Clin Microbiol. 1988;26:142-143.
    • (1988) J Clin Microbiol. , vol.26 , pp. 142-143
    • Romero, S.1    Archer, J.R.2    Hamacher, M.E.3
  • 27
    • 0023830143 scopus 로고
    • Characterization of an unclassified microaerophilic bacterium associated with gastroenteritis
    • Archer JR, Romero S, Ritchie AE, et al. Characterization of an unclassified microaerophilic bacterium associated with gastroenteritis. J Clin Microbiol. 1988;26:101-105.
    • (1988) J Clin Microbiol. , vol.26 , pp. 101-105
    • Archer, J.R.1    Romero, S.2    Ritchie, A.E.3
  • 28
    • 17044425824 scopus 로고    scopus 로고
    • Extension of the species Helicobacter bilis to include the reference strains of Helicobacter sp. Flexispira taxa 2, 3 and 8 and Finnish canine and feline flexispira strains
    • Hanninen ML, Karenlampi RI, Koort JM, et al. Extension of the species Helicobacter bilis to include the reference strains of Helicobacter sp. flexispira taxa 2, 3 and 8 and Finnish canine and feline flexispira strains. Int J Syst Evol Microbiol. 2005;55:891-898.
    • (2005) Int J Syst Evol Microbiol. , vol.55 , pp. 891-898
    • Hanninen, M.L.1    Karenlampi, R.I.2    Koort, J.M.3
  • 29
    • 0032425062 scopus 로고    scopus 로고
    • Helicobacter hepaticus triggers colitis in specific-pathogen-free interleukin-10 (IL-10)-deficient mice through an IL-12- and gamma interferon-dependent mechanism
    • Kullberg MC, Ward JM, Gorelick PL, et al. Helicobacter hepaticus triggers colitis in specific-pathogen-free interleukin-10 (IL-10)-deficient mice through an IL-12- and gamma interferon-dependent mechanism. Infect Immun. 1998;66:5157-5166.
    • (1998) Infect Immun. , vol.66 , pp. 5157-5166
    • Kullberg, M.C.1    Ward, J.M.2    Gorelick, P.L.3
  • 30
    • 0033041980 scopus 로고    scopus 로고
    • A novel urease-negative Helicobacter species associated with colitis and typhlitis in IL-10-deficient mice
    • Fox JG, Gorelick PL, Kullberg MC, et al. A novel urease-negative Helicobacter species associated with colitis and typhlitis in IL-10-deficient mice. Infect Immun. 1999;67:1757-1762.
    • (1999) Infect Immun. , vol.67 , pp. 1757-1762
    • Fox, J.G.1    Gorelick, P.L.2    Kullberg, M.C.3
  • 31
    • 0031668308 scopus 로고    scopus 로고
    • Enterohepatic lesions in SCID mice infected with Helicobacter bilis
    • Franklin CL, Riley LK, Livingston RS, et al. Enterohepatic lesions in SCID mice infected with Helicobacter bilis. Lab Anim Sci. 1998;48: 334-339.
    • (1998) Lab Anim Sci. , vol.48 , pp. 334-339
    • Franklin, C.L.1    Riley, L.K.2    Livingston, R.S.3
  • 32
    • 0031772881 scopus 로고    scopus 로고
    • Helicobacter bilis/Helicobacter rodentium co-infection associated with diarrhea in a colony of scid mice
    • Shomer NH, Dangler CA, Marini RP, et al. Helicobacter bilis/Helicobacter rodentium co-infection associated with diarrhea in a colony of scid mice. Lab Anim Sci. 1998;48:455-459.
    • (1998) Lab Anim Sci. , vol.48 , pp. 455-459
    • Shomer, N.H.1    Dangler, C.A.2    Marini, R.P.3
  • 33
    • 0030735193 scopus 로고    scopus 로고
    • Helicobacter bilis-induced inflammatory bowel disease in scid mice with defined flora
    • Shomer NH, Dangler CA, Schrenzel MD, et al. Helicobacter bilis-induced inflammatory bowel disease in scid mice with defined flora. Infect Immun. 1997;65:4858-4864.
    • (1997) Infect Immun. , vol.65 , pp. 4858-4864
    • Shomer, N.H.1    Dangler, C.A.2    Schrenzel, M.D.3
  • 34
    • 0036169116 scopus 로고    scopus 로고
    • Helicobacter bilis infection accelerates and H. Hepaticus infection delays the development of colitis in multiple drug resistance-deficient (mdr1a-/-) mice
    • Maggio-Price L, Shows D, Waggie K, et al. Helicobacter bilis infection accelerates and H. hepaticus infection delays the development of colitis in multiple drug resistance-deficient (mdr1a-/-) mice. Am J Pathol. 2002; 160:739-751.
    • (2002) Am J Pathol. , vol.160 , pp. 739-751
    • Maggio-Price, L.1    Shows, D.2    Waggie, K.3
  • 35
    • 0037331279 scopus 로고    scopus 로고
    • CD4+ CD25+ regulatory T lymphocytes inhibit microbially induced colon cancer in Rag2-deficient mice
    • Erdman SE, Poutahidis T, Tomczak M, et al. CD4+ CD25+ regulatory T lymphocytes inhibit microbially induced colon cancer in Rag2-deficient mice. Am J Pathol. 2003;162:691-702.
    • (2003) Am J Pathol. , vol.162 , pp. 691-702
    • Erdman, S.E.1    Poutahidis, T.2    Tomczak, M.3
  • 36
    • 38349050145 scopus 로고    scopus 로고
    • Helicobacter hepaticus promotes azoxymethane-initiated colon tumorigenesis in BALB/c-IL10-deficient mice
    • Nagamine CM, Rogers AB, Fox JG, et al. Helicobacter hepaticus promotes azoxymethane-initiated colon tumorigenesis in BALB/c-IL10-deficient mice. Int J Cancer. 2008;122:832-838.
    • (2008) Int J Cancer. , vol.122 , pp. 832-838
    • Nagamine, C.M.1    Rogers, A.B.2    Fox, J.G.3
  • 37
    • 46249085505 scopus 로고    scopus 로고
    • Helicobacter hepaticus infection promotes colon tumorigenesis in the BALB/c-Rag2(-/-) Apc (Min/+) mouse
    • Nagamine CM, Sohn JJ, Rickman BH, et al. Helicobacter hepaticus infection promotes colon tumorigenesis in the BALB/c-Rag2(-/-) Apc (Min/+) mouse. Infect Immun. 2008;76:2758-2766.
    • (2008) Infect Immun. , vol.76 , pp. 2758-2766
    • Nagamine, C.M.1    Sohn, J.J.2    Rickman, B.H.3
  • 38
    • 21144434501 scopus 로고    scopus 로고
    • Dual infection with Helicobacter bilis and Helicobacter hepaticus in p-glycoprotein-deficient mdr1a-/- mice results in colitis that progresses to dysplasia
    • Maggio-Price L, Bielefeldt-Ohmann H, Treuting P, et al. Dual infection with Helicobacter bilis and Helicobacter hepaticus in p-glycoprotein-deficient mdr1a-/- mice results in colitis that progresses to dysplasia. Am J Pathol. 2005;166:1793-1806.
    • (2005) Am J Pathol. , vol.166 , pp. 1793-1806
    • Maggio-Price, L.1    Bielefeldt-Ohmann, H.2    Treuting, P.3
  • 39
    • 31544465904 scopus 로고    scopus 로고
    • Helicobacter infection is required for inflammation and colon cancer in SMAD3-deficient mice
    • Maggio-Price L, Treuting P, Zeng W, et al. Helicobacter infection is required for inflammation and colon cancer in SMAD3-deficient mice. Cancer Res. 2006;66:828-838.
    • (2006) Cancer Res. , vol.66 , pp. 828-838
    • Maggio-Price, L.1    Treuting, P.2    Zeng, W.3
  • 40
    • 58249099947 scopus 로고    scopus 로고
    • Bacterial infection of Smad3/Rag2 double-null mice with transforming growth factorbeta dysregulation as a model for studying inflammation-associated colon cancer
    • Maggio-Price L, Treuting P, Bielefeldt-Ohmann H, et al. Bacterial infection of Smad3/Rag2 double-null mice with transforming growth factorbeta dysregulation as a model for studying inflammation-associated colon cancer. Am J Pathol. 2009;174:317-329.
    • (2009) Am J Pathol. , vol.174 , pp. 317-329
    • Maggio-Price, L.1    Treuting, P.2    Bielefeldt-Ohmann, H.3
  • 41
    • 0031899969 scopus 로고    scopus 로고
    • Hepatic helicobacter species identified in bile and gallbladder tissue from Chileans with chronic cholecystitis
    • Fox JG, Dewhirst FE, Shen Z, et al. Hepatic Helicobacter species identified in bile and gallbladder tissue from Chileans with chronic cholecystitis. Gastroenterology. 1998;114:755-763.
    • (1998) Gastroenterology. , vol.114 , pp. 755-763
    • Fox, J.G.1    Dewhirst, F.E.2    Shen, Z.3
  • 42
    • 65549144674 scopus 로고    scopus 로고
    • Helicobacter-based mouse models of digestive system carcinogenesis
    • Rogers AB, Houghton J. Helicobacter-based mouse models of digestive system carcinogenesis. Methods Mol Biol. 2009;511:267-295.
    • (2009) Methods Mol Biol. , vol.511 , pp. 267-295
    • Rogers, A.B.1    Houghton, J.2
  • 43
    • 84865461925 scopus 로고    scopus 로고
    • Wiskott-Aldrich syndrome protein deficiency in innate immune cells leads to mucosal immune dysregulation and colitis in mice
    • Nguyen DD, Wurbel MA, Goettel JA, et al. Wiskott-Aldrich syndrome protein deficiency in innate immune cells leads to mucosal immune dysregulation and colitis in mice. Gastroenterology. 2012;143:719-729.
    • (2012) Gastroenterology. , vol.143 , pp. 719-729
    • Nguyen, D.D.1    Wurbel, M.A.2    Goettel, J.A.3
  • 44
    • 0037443395 scopus 로고    scopus 로고
    • Gene therapy for Wiskott-Aldrich syndrome: Rescue of T-cell signaling and amelioration of colitis upon transplantation of retrovirally transduced hematopoietic stem cells in mice
    • Klein C, Nguyen D, Liu CH, et al. Gene therapy for Wiskott-Aldrich syndrome: rescue of T-cell signaling and amelioration of colitis upon transplantation of retrovirally transduced hematopoietic stem cells in mice. Blood. 2003;101:2159-2166.
    • (2003) Blood. , vol.101 , pp. 2159-2166
    • Klein, C.1    Nguyen, D.2    Liu, C.H.3
  • 45
    • 0035260357 scopus 로고    scopus 로고
    • Typhlocolitis in NF-kappa B-deficient mice
    • Erdman S, Fox JG, Dangler CA, et al. Typhlocolitis in NF-kappa B-deficient mice. J Immunol. 2001;166:1443-1447.
    • (2001) J Immunol. , vol.166 , pp. 1443-1447
    • Erdman, S.1    Fox, J.G.2    Dangler, C.A.3
  • 46
    • 0034503471 scopus 로고    scopus 로고
    • Helicobacter hepaticus infection triggers inflammatory bowel disease in T cell receptor alphabeta mutant mice
    • Chin EY, Dangler CA, Fox JG, et al. Helicobacter hepaticus infection triggers inflammatory bowel disease in T cell receptor alphabeta mutant mice. Comp Med. 2000;50:586-594.
    • (2000) Comp Med. , vol.50 , pp. 586-594
    • Chin, E.Y.1    Dangler, C.A.2    Fox, J.G.3
  • 47
    • 56549121232 scopus 로고    scopus 로고
    • Helicobacter typhlonius and Helicobacter rodentium differentially affect the severity of colon inflammation and inflammation-associated neoplasia in IL10-deficient mice
    • Chichlowski M, Sharp JM, Vanderford DA, et al. Helicobacter typhlonius and Helicobacter rodentium differentially affect the severity of colon inflammation and inflammation-associated neoplasia in IL10-deficient mice. Comp Med. 2008;58:534-541.
    • (2008) Comp Med. , vol.58 , pp. 534-541
    • Chichlowski, M.1    Sharp, J.M.2    Vanderford, D.A.3
  • 48
    • 36248936620 scopus 로고    scopus 로고
    • Neonatal co-infection with helicobacter species markedly accelerates the development of inflammationassociated colonic neoplasia in IL-10(-/-) mice
    • Hale LP, Perera D, Gottfried MR, et al. Neonatal co-infection with helicobacter species markedly accelerates the development of inflammationassociated colonic neoplasia in IL-10(-/-) mice. Helicobacter. 2007;12: 598-604.
    • (2007) Helicobacter , vol.12 , pp. 598-604
    • Hale, L.P.1    Perera, D.2    Gottfried, M.R.3
  • 49
    • 78650113104 scopus 로고    scopus 로고
    • Rho kinase signalling mediates radiation-induced inflammation and intestinal barrier dysfunction
    • Mihaescu A, Santen S, Jeppsson B, et al. Rho kinase signalling mediates radiation-induced inflammation and intestinal barrier dysfunction. Br J Surg. 2011;98:124-131.
    • (2011) Br J Surg. , vol.98 , pp. 124-131
    • Mihaescu, A.1    Santen, S.2    Jeppsson, B.3


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