Toward the design of new DNA G-quadruplex ligands through rational analysis of polymorphism and binding data

European Journal of Medicinal Chemistry

Volumn 68, Issue , 2013, Pages 139-149

  Artese, Anna ^a   Costa, Giosuè ^a   Distinto, Simona ^b   Moraca, Federica ^a   Ortuso, Francesco ^a   Parrotta, Lucia ^a   Alcaro, Stefano ^a  

^a UNIVERSITY MAGNA GRAECIA OF CATANZARO   (Italy)

^b UNIVERSITY OF CAGLIARI   (Italy)

Author keywords

Cancer; DNA; Docking; G quadruplex; Linear correlation; PDB; Polymorphism; Telomere; TRAP assays

Indexed keywords

ACRIDINE; DIBENZOPHENANTHROLINE; GUANINE; GUANINE QUADRUPLEX; RNA DIRECTED DNA POLYMERASE; UNCLASSIFIED DRUG;

ARTICLE; DNA CONFORMATION; DNA STRAND; GENETIC POLYMORPHISM; HUMAN; PROTEIN DATA BANK; PROTEIN STRUCTURE; TELOMERE; TELOMERE HOMEOSTASIS;

CANCER; DNA; DOCKING; G-QUADRUPLEX; LINEAR CORRELATION; PDB; POLYMORPHISM; TELOMERE; TRAP ASSAYS;

G-QUADRUPLEXES; HUMANS; HYDROGEN BONDING; LIGANDS; MODELS, MOLECULAR; NUCLEIC ACID CONFORMATION; POLYMORPHISM, GENETIC;

EID: 84884493796     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2013.07.022     Document Type: Article

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