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Volumn 18, Issue 14, 2012, Pages 1873-1879

The polymorphisms of DNA G-quadruplex investigated by docking experiments with telomestatin enantiomers

Author keywords

DNA; Docking; G quadruplex; Geometrical Descriptor; Polymorphism; Telomestatin

Indexed keywords

GUANINE QUADRUPLEX; TELOMESTATIN;

EID: 84860143899     PISSN: 13816128     EISSN: 18734286     Source Type: Journal    
DOI: 10.2174/138161212799958495     Document Type: Article
Times cited : (24)

References (68)
  • 1
    • 0030982721 scopus 로고    scopus 로고
    • The terminal DNA structure of mammalian chromosomes
    • McElligott R, Wellinger RJ. The terminal DNA structure of mammalian chromosomes. EMBO J 1997; 16: 3705-3714.
    • (1997) EMBO J , vol.16 , pp. 3705-3714
    • McElligott, R.1    Wellinger, R.J.2
  • 2
    • 0025279931 scopus 로고
    • Telomeres shorten during ageing of human fibroblasts
    • Harley CB, Futcher AB, Greider CW. Telomeres shorten during ageing of human fibroblasts. Nature 1990; 345: 458-460.
    • (1990) Nature , vol.345 , pp. 458-460
    • Harley, C.B.1    Futcher, A.B.2    Greider, C.W.3
  • 5
    • 33749631593 scopus 로고    scopus 로고
    • Telomeres: Prognostic markers for solid tumors
    • Bisoffi M, Heaphy CM, Griffith JK. Telomeres: Prognostic markers for solid tumors. Int J Cancer 2006; 119: 2255-2260.
    • (2006) Int J Cancer , vol.119 , pp. 2255-2260
    • Bisoffi, M.1    Heaphy, C.M.2    Griffith, J.K.3
  • 6
    • 18044391665 scopus 로고    scopus 로고
    • Overcoming the immortality of tumour cells by telomere and telomerase based cancer therapeutics - current status and future prospects
    • Kelland LR. Overcoming the immortality of tumour cells by telomere and telomerase based cancer therapeutics - current status and future prospects. Eur J Cancer 2005; 41: 971-979.
    • (2005) Eur J Cancer , vol.41 , pp. 971-979
    • Kelland, L.R.1
  • 8
    • 38049030699 scopus 로고    scopus 로고
    • Human telomere, oncogenic promoter and 5'-UTR G-quadruplexes: Diverse higher order DNA and RNA targets for cancer therapeutics
    • Patel DJ, Phan AT, Kuryavyi V. Human telomere, oncogenic promoter and 5'-UTR G-quadruplexes: diverse higher order DNA and RNA targets for cancer therapeutics. Nucleic Acids Res 2007; 35: 7429-7455.
    • (2007) Nucleic Acids Res , vol.35 , pp. 7429-7455
    • Patel, D.J.1    Phan, A.T.2    Kuryavyi, V.3
  • 9
    • 56249129385 scopus 로고    scopus 로고
    • Chapter 4 Metal ion interactions with G-quadruplex structures. In: Ed.eds., Nucleic Acid-Metal Ion Interactions
    • Engelhart AE, Plavec J, Persil O, Hud NV. Chapter 4 Metal ion interactions with G-quadruplex structures. In: ed.eds., Nucleic Acid-Metal Ion Interactions. The Royal Society of Chemistry 2009; pp. 118-153.
    • The Royal Society of Chemistry , vol.2009 , pp. 118-153
    • Engelhart, A.E.1    Plavec, J.2    Persil, O.3    Hud, N.V.4
  • 10
    • 66549124907 scopus 로고    scopus 로고
    • The structures of quadruplex nucleic acids and their drug complexes
    • Neidle S. The structures of quadruplex nucleic acids and their drug complexes. Curr Opin Struct Biol 2009; 19: 239-250.
    • (2009) Curr Opin Struct Biol , vol.19 , pp. 239-250
    • Neidle, S.1
  • 11
    • 84860140562 scopus 로고    scopus 로고
    • http://www.rcsb.org/
  • 12
    • 0027918585 scopus 로고
    • Solution structure of the human telomeric repeat d[AG3(T2AG3)3] G-tetraplex
    • Wang Y, Patel DJ. Solution structure of the human telomeric repeat d[AG3(T2AG3)3] G-tetraplex. Structure 1993; 1: 263-282.
    • (1993) Structure , vol.1 , pp. 263-282
    • Wang, Y.1    Patel, D.J.2
  • 13
    • 0037142071 scopus 로고    scopus 로고
    • Crystal structure of parallel quadruplexes from human telomeric DNA
    • Parkinson GN, Lee MPH, Neidle S. Crystal structure of parallel quadruplexes from human telomeric DNA. Nature 2002; 417: 876-880.
    • (2002) Nature , vol.417 , pp. 876-880
    • Parkinson, G.N.1    Lee, M.P.H.2    Neidle, S.3
  • 14
    • 0345098322 scopus 로고    scopus 로고
    • Two-repeat human telomeric d(TAGGGTTAGGGT) sequence forms interconverting parallel and antiparallel G-quadruplexes in solution: Distinct topologies, thermodynamic properties, and folding/unfolding kinetics
    • Phan AT, Patel DJ. Two-repeat human telomeric d(TAGGGTTAGGGT) sequence forms interconverting parallel and antiparallel G-quadruplexes in solution: distinct topologies, thermodynamic properties, and folding/unfolding kinetics. J Am Chem Soc 2003; 125: 15021-15027.
    • (2003) J Am Chem Soc , vol.125 , pp. 15021-15027
    • Phan, A.T.1    Patel, D.J.2
  • 15
    • 0344304471 scopus 로고    scopus 로고
    • Studies on the structure and dynamics of the human telomeric G quadruplex by single-molecule fluorescence resonance energy transfer
    • Ying L, Green JJ, Li H, Klenerman D, Balasubramanian S. Studies on the structure and dynamics of the human telomeric G quadruplex by single-molecule fluorescence resonance energy transfer. Proc Natl Acad Sci USA 2003; 100: 14629-14634.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 14629-14634
    • Ying, L.1    Green, J.J.2    Li, H.3    Klenerman, D.4    Balasubramanian, S.5
  • 16
    • 2442676468 scopus 로고    scopus 로고
    • Highly efficient photochemical 2'-deoxyribonolactone formation at the diagonal loop of a 5-iodouracil-containing antiparallel G-quartet
    • Xu Y, Sugiyama H. Highly efficient photochemical 2'-deoxyribonolactone formation at the diagonal loop of a 5-iodouracil-containing antiparallel G-quartet. J Am Chem Soc 2004; 126: 6274-6279.
    • (2004) J Am Chem Soc , vol.126 , pp. 6274-6279
    • Xu, Y.1    Sugiyama, H.2
  • 18
    • 21644460419 scopus 로고    scopus 로고
    • Telomestatin and diseleno sapphyrin bind selectively to two different forms of the human telomeric G-quadruplex structure
    • Rezler EM, Seenisamy J, Bashyam S, Kim M-Y, White E, Wilson WD, Hurley LH. Telomestatin and diseleno sapphyrin bind selectively to two different forms of the human telomeric G-quadruplex structure. J Am Chem Soc 2005; 127: 9439-9447.
    • (2005) J Am Chem Soc , vol.127 , pp. 9439-9447
    • Rezler, E.M.1    Seenisamy, J.2    Bashyam, S.3    Kim, M.-Y.4    White, E.5    Wilson, W.D.6    Hurley, L.H.7
  • 19
    • 17144371894 scopus 로고    scopus 로고
    • Vertebrate telomere repeat DNAs favor external loop propeller quadruplex structures in the presence of high concentrations of potassium
    • Rujan IN, Meleney JC, Bolton PH. Vertebrate telomere repeat DNAs favor external loop propeller quadruplex structures in the presence of high concentrations of potassium. Nucleic Acids Res 2005; 33: 2022-2031.
    • (2005) Nucleic Acids Res , vol.33 , pp. 2022-2031
    • Rujan, I.N.1    Meleney, J.C.2    Bolton, P.H.3
  • 20
    • 20144365697 scopus 로고    scopus 로고
    • Covalent ligation studies on the human telomere quadruplex
    • Qi J, Shafer RH. Covalent ligation studies on the human telomere quadruplex. Nucleic Acids Res 2005; 33: 3185-3192.
    • (2005) Nucleic Acids Res , vol.33 , pp. 3185-3192
    • Qi, J.1    Shafer, R.H.2
  • 21
    • 23244433818 scopus 로고    scopus 로고
    • Cross-links of quadruplex structures from human telomeric DNA by dinuclear platinum complexes show the flexibility of both structures
    • Ourliac-Garnier I, Elizondo-Riojas M-A, Redon S, Farrell NP, Bombard S. Cross-links of quadruplex structures from human telomeric DNA by dinuclear platinum complexes show the flexibility of both structures. Biochemistry 2005; 44: 10620-10634.
    • (2005) Biochemistry , vol.44 , pp. 10620-10634
    • Ourliac-Garnier, I.1    Elizondo-Riojas, M.-A.2    Redon, S.3    Farrell, N.P.4    Bombard, S.5
  • 22
    • 30044448463 scopus 로고    scopus 로고
    • Extreme conformational diversity in human telomeric DNA
    • Lee JY, Okumus B, Kim DS, Ha T. Extreme conformational diversity in human telomeric DNA. Proc Natl Acad Sci USA 2005; 102: 18938-18943.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 18938-18943
    • Lee, J.Y.1    Okumus, B.2    Kim, D.S.3    Ha, T.4
  • 23
    • 33845294453 scopus 로고    scopus 로고
    • Characterization of structure and stability of long telomeric DNA G-quadruplexes
    • Yu H-Q, Miyoshi D, Sugimoto N. Characterization of structure and stability of long telomeric DNA G-quadruplexes. J Am Chem Soc 2006; 128: 15461-15468.
    • (2006) J Am Chem Soc , vol.128 , pp. 15461-15468
    • Yu, H.-Q.1    Miyoshi, D.2    Sugimoto, N.3
  • 24
    • 34249846802 scopus 로고    scopus 로고
    • Structure of the intramolecular human telomeric G-quadruplex in potassium solution: A novel adenine triple formation
    • Dai J, Punchihewa C, Ambrus A, Chen D, Jones RA, Yang D. Structure of the intramolecular human telomeric G-quadruplex in potassium solution: a novel adenine triple formation. Nucleic Acids Res 2007; 35: 2440-2450.
    • (2007) Nucleic Acids Res , vol.35 , pp. 2440-2450
    • Dai, J.1    Punchihewa, C.2    Ambrus, A.3    Chen, D.4    Jones, R.A.5    Yang, D.6
  • 25
    • 34548550548 scopus 로고    scopus 로고
    • Structure of the Hybrid-2 type intramolecular human telomeric G-quadruplex in K+ solution: Insights into structure polymorphism of the human telomeric sequence
    • Dai J, Carver M, Punchihewa C, Jones RA, Yang D. Structure of the Hybrid-2 type intramolecular human telomeric G-quadruplex in K+ solution: insights into structure polymorphism of the human telomeric sequence. Nucleic Acids Res 2007; 35: 4927-4940.
    • (2007) Nucleic Acids Res , vol.35 , pp. 4927-4940
    • Dai, J.1    Carver, M.2    Punchihewa, C.3    Jones, R.A.4    Yang, D.5
  • 26
    • 36148991081 scopus 로고    scopus 로고
    • Structure of two intramolecular G-quadruplexes formed by natural human telomere sequences in K+ solution
    • Phan AT, Kuryavyi V, Luu KN, Patel DJ. Structure of two intramolecular G-quadruplexes formed by natural human telomere sequences in K+ solution. Nucleic Acids Res 2007; 35: 6517-6525.
    • (2007) Nucleic Acids Res , vol.35 , pp. 6517-6525
    • Phan, A.T.1    Kuryavyi, V.2    Luu, K.N.3    Patel, D.J.4
  • 27
    • 33646943863 scopus 로고    scopus 로고
    • Human telomeric sequence forms a hybrid-type intramolecular G-quadruplex structure with mixed parallel/antiparallel strands in potassium solution
    • Ambrus A, Chen D, Dai J, Bialis T, Jones RA, Yang D. Human telomeric sequence forms a hybrid-type intramolecular G-quadruplex structure with mixed parallel/antiparallel strands in potassium solution. Nucleic Acids Res 2006; 34: 2723-2735.
    • (2006) Nucleic Acids Res , vol.34 , pp. 2723-2735
    • Ambrus, A.1    Chen, D.2    Dai, J.3    Bialis, T.4    Jones, R.A.5    Yang, D.6
  • 28
    • 33746600695 scopus 로고    scopus 로고
    • Structure of the human telomere in K+ solution: An Intramolecular (3 + 1) G-quadruplex scaffold
    • Luu KN, Phan AT, Kuryavyi V, Lacroix L, Patel DJ. Structure of the human telomere in K+ solution: an Intramolecular (3 + 1) G-quadruplex scaffold. J Am Chem Soc 2006; 128: 9963-9970.
    • (2006) J Am Chem Soc , vol.128 , pp. 9963-9970
    • Luu, K.N.1    Phan, A.T.2    Kuryavyi, V.3    Lacroix, L.4    Patel, D.J.5
  • 29
    • 33750970018 scopus 로고    scopus 로고
    • Different loop arrangements of intramolecular human telomeric (3+1) G-quadruplexes in K+ solution
    • Phan AT, Luu KN, Patel DJ. Different loop arrangements of intramolecular human telomeric (3+1) G-quadruplexes in K+ solution. Nucleic Acids Res 2006; 34: 5715-5719.
    • (2006) Nucleic Acids Res , vol.34 , pp. 5715-5719
    • Phan, A.T.1    Luu, K.N.2    Patel, D.J.3
  • 30
    • 0030786928 scopus 로고    scopus 로고
    • Inhibition of human telomerase by a G-quadruplex-interactive compound
    • Sun D, Thompson B, Cathers BE, et al. Inhibition of human telomerase by a G-quadruplex-interactive compound. J Med Chem 1997; 40: 2113-2116.
    • (1997) J Med Chem , vol.40 , pp. 2113-2116
    • Sun, D.1    Thompson, B.2    Cathers, B.E.3
  • 31
    • 33745679352 scopus 로고    scopus 로고
    • Telomerase therapeutics for cancer: Challenges and new directions
    • Shay JW, Wright WE. Telomerase therapeutics for cancer: challenges and new directions. Nat Rev Drug Discov 2006; 5: 577-584.
    • (2006) Nat Rev Drug Discov , vol.5 , pp. 577-584
    • Shay, J.W.1    Wright, W.E.2
  • 32
    • 33847372902 scopus 로고    scopus 로고
    • Physiological relevance of telomeric G-quadruplex formation: A potential drug target
    • Oganesian L, Bryan TM. Physiological relevance of telomeric G-quadruplex formation: a potential drug target. BioEssays 2007; 29: 155-165.
    • (2007) BioEssays , vol.29 , pp. 155-165
    • Oganesian, L.1    Bryan, T.M.2
  • 33
    • 37049004147 scopus 로고    scopus 로고
    • Targeting telomeres and telomerase
    • De Cian A, Lacroix L, Douarre C, et al. Targeting telomeres and telomerase. Biochimie 2008; 90: 131-155.
    • (2008) Biochimie , vol.90 , pp. 131-155
    • de Cian, A.1    Lacroix, L.2    Douarre, C.3
  • 34
    • 39049147645 scopus 로고    scopus 로고
    • A hitchhiker's guide to G-quadruplex ligands
    • Monchaud D, Teulade-Fichou MP. A hitchhiker's guide to G-quadruplex ligands. Org Biomol Chem 2008; 6: 627-636.
    • (2008) Org Biomol Chem , vol.6 , pp. 627-636
    • Monchaud, D.1    Teulade-Fichou, M.P.2
  • 35
    • 79960697965 scopus 로고    scopus 로고
    • Conformational studies and solvent-accessible surface area analysis of known selective DNA G-Quadruplex binders
    • In Press, Corrected Proof
    • Alcaro S, Artese A, Costa G, Distinto S, Ortuso F, Parrotta L. Conformational studies and solvent-accessible surface area analysis of known selective DNA G-Quadruplex binders. Biochimie 2011; In Press, Corrected Proof.
    • (2011) Biochimie
    • Alcaro, S.1    Artese, A.2    Costa, G.3    Distinto, S.4    Ortuso, F.5    Parrotta, L.6
  • 36
    • 0035857396 scopus 로고    scopus 로고
    • Telomestatin, a novel telomerase inhibitor from Streptomyces anulatus
    • Shin-ya K, Wierzba K, Matsuo K, et al. Telomestatin, a novel telomerase inhibitor from Streptomyces anulatus. J Am Chem Soc 2001; 123: 1262-1263.
    • (2001) J Am Chem Soc , vol.123 , pp. 1262-1263
    • Shin-Ya, K.1    Wierzba, K.2    Matsuo, K.3
  • 37
    • 0037070575 scopus 로고    scopus 로고
    • Telomestatin, a potent telomerase inhibitor that interacts quite specifically with the human telomeric intramolecular G-quadruplex
    • Kim MY, Vankayalapati H, Shin-ya K, Wierzba K, Hurley LH. Telomestatin, a potent telomerase inhibitor that interacts quite specifically with the human telomeric intramolecular G-quadruplex. J Am Chem Soc 2002; 124: 2098-2099.
    • (2002) J Am Chem Soc , vol.124 , pp. 2098-2099
    • Kim, M.Y.1    Vankayalapati, H.2    Shin-Ya, K.3    Wierzba, K.4    Hurley, L.H.5
  • 38
    • 0033566092 scopus 로고    scopus 로고
    • 2,7-Disubstituted amidofluorenone derivatives as inhibitors of human telomerase
    • Perry PJ, Read MA, Davies RT, et al. 2,7-Disubstituted amidofluorenone derivatives as inhibitors of human telomerase. J Med Chem 1999; 42: 2679-2684.
    • (1999) J Med Chem , vol.42 , pp. 2679-2684
    • Perry, P.J.1    Read, M.A.2    Davies, R.T.3
  • 39
    • 0035282707 scopus 로고    scopus 로고
    • Ethidium derivatives bind to G-quartets, inhibit telomerase and act as fluorescent probes for quadruplexes
    • Koeppel F, Riou JF, Laoui A, et al. Ethidium derivatives bind to G-quartets, inhibit telomerase and act as fluorescent probes for quadruplexes. Nucleic Acids Res 2001; 29: 1087-1096.
    • (2001) Nucleic Acids Res , vol.29 , pp. 1087-1096
    • Koeppel, F.1    Riou, J.F.2    Laoui, A.3
  • 40
    • 7044249456 scopus 로고    scopus 로고
    • Evaluation of by disubstituted acridone derivatives as telomerase inhibitors: The importance of G-quadruplex binding
    • Harrison RJ, Reszka AP, Haider SM, et al. Evaluation of by disubstituted acridone derivatives as telomerase inhibitors: the importance of G-quadruplex binding. Bioorg Med Chem Lett 2004; 14: 5845-5849.
    • (2004) Bioorg Med Chem Lett , vol.14 , pp. 5845-5849
    • Harrison, R.J.1    Reszka, A.P.2    Haider, S.M.3
  • 43
    • 0035553175 scopus 로고    scopus 로고
    • Design and synthesis of fluoroquinophenoxazines that interact with human telomeric G-quadruplexes and their biological effects
    • Duan W, Rangan A, Vankayalapati H, et al. Design and synthesis of fluoroquinophenoxazines that interact with human telomeric G-quadruplexes and their biological effects. Mol Cancer Ther 2001; 1: 103-120.
    • (2001) Mol Cancer Ther , vol.1 , pp. 103-120
    • Duan, W.1    Rangan, A.2    Vankayalapati, H.3
  • 45
    • 0037041260 scopus 로고    scopus 로고
    • Benzoindoloquinolines interact with DNA tetraplexes and inhibit telomerase
    • Alberti P, Schmitt P, Nguyen CH, et al. Benzoindoloquinolines interact with DNA tetraplexes and inhibit telomerase. Bioorg Med Chem Lett 2002; 12: 1071-1074.
    • (2002) Bioorg Med Chem Lett , vol.12 , pp. 1071-1074
    • Alberti, P.1    Schmitt, P.2    Nguyen, C.H.3
  • 46
    • 0033812999 scopus 로고    scopus 로고
    • A novel inhibitor of human telomerase derived from 10H-indolo[3,2-b]quinoline
    • Caprio V, Guyen B, Opoku-Boahen Y, et al. A novel inhibitor of human telomerase derived from 10H-indolo[3,2-b]quinoline. Bioorg Med Chem Lett 2000; 10: 2063-2066.
    • (2000) Bioorg Med Chem Lett , vol.10 , pp. 2063-2066
    • Caprio, V.1    Guyen, B.2    Opoku-Boahen, Y.3
  • 47
    • 2342568938 scopus 로고    scopus 로고
    • Synthesis and evaluation of analogues of 10H-indolo[3,2-b]quinoline as G-quadruplex stabilising ligands and potential inhibitors of the enzyme telomerase
    • Guyen B, Schultes CM, Hazel P, Mann J, Neidle S. Synthesis and evaluation of analogues of 10H-indolo[3,2-b]quinoline as G-quadruplex stabilising ligands and potential inhibitors of the enzyme telomerase. Org Biomol Chem 2004; 2: 981-988.
    • (2004) Org Biomol Chem , vol.2 , pp. 981-988
    • Guyen, B.1    Schultes, C.M.2    Hazel, P.3    Mann, J.4    Neidle, S.5
  • 48
    • 0037518359 scopus 로고    scopus 로고
    • Interactions of cryptolepine and neocryptolepine with unusual DNA structures
    • Guittat L, Alberti P, Rosu F, et al. Interactions of cryptolepine and neocryptolepine with unusual DNA structures. Biochimie 2003; 85: 535-547.
    • (2003) Biochimie , vol.85 , pp. 535-547
    • Guittat, L.1    Alberti, P.2    Rosu, F.3
  • 49
    • 28544447925 scopus 로고    scopus 로고
    • Synthesis and evaluation of quindoline derivatives as G-quadruplex inducing and stabilizing ligands and potential inhibitors of telomerase
    • Zhou JL, Lu YJ, Ou TM, et al. Synthesis and evaluation of quindoline derivatives as G-quadruplex inducing and stabilizing ligands and potential inhibitors of telomerase. J Med Chem 2005; 48: 7315-7321.
    • (2005) J Med Chem , vol.48 , pp. 7315-7321
    • Zhou, J.L.1    Lu, Y.J.2    Ou, T.M.3
  • 50
    • 0035924232 scopus 로고    scopus 로고
    • Quadruplex interactive agents as telomerase inhibitors: Synthesis of porphyrins and structure-activity relationship for the inhibition of telomerase
    • Shi DF, Wheelhouse RT, Sun D, Hurley LH. Quadruplex interactive agents as telomerase inhibitors: synthesis of porphyrins and structure-activity relationship for the inhibition of telomerase. J Med Chem 2001; 44: 4509-4523.
    • (2001) J Med Chem , vol.44 , pp. 4509-4523
    • Shi, D.F.1    Wheelhouse, R.T.2    Sun, D.3    Hurley, L.H.4
  • 51
    • 0035853164 scopus 로고    scopus 로고
    • Telomerase inhibitors based on quadruplex ligands selected by a fluorescence assay
    • Mergny JL, Lacroix L, Teulade-Fichou MP, et al. Telomerase inhibitors based on quadruplex ligands selected by a fluorescence assay. Proc Natl Acad Sci USA 2001; 98: 3062-3067.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 3062-3067
    • Mergny, J.L.1    Lacroix, L.2    Teulade-Fichou, M.P.3
  • 52
    • 0037022658 scopus 로고    scopus 로고
    • Cell senescence and telomere shortening induced by a new series of specific G-quadruplex DNA ligands
    • Riou JF, Guittat L, Mailliet P, et al. Cell senescence and telomere shortening induced by a new series of specific G-quadruplex DNA ligands. Proc Natl Acad Sci USA 2002; 99: 2672-2677.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 2672-2677
    • Riou, J.F.1    Guittat, L.2    Mailliet, P.3
  • 53
    • 3543039438 scopus 로고    scopus 로고
    • Detection of quadruplex DNA structures in human telomeres by a fluorescent carbazole derivative
    • Chang CC, Kuo IC, Ling IF, et al. Detection of quadruplex DNA structures in human telomeres by a fluorescent carbazole derivative. Anal Chem 2004; 76: 4490-4494.
    • (2004) Anal Chem , vol.76 , pp. 4490-4494
    • Chang, C.C.1    Kuo, I.C.2    Ling, I.F.3
  • 54
    • 33947732873 scopus 로고    scopus 로고
    • Tetraplex DNA specific ligands based on the fluorenone-carboxamide scaffold
    • Alcaro S, Artese A, Iley JN, et al. Tetraplex DNA specific ligands based on the fluorenone-carboxamide scaffold. Bioorg Med Chem Lett 2007; 17: 2509-2514.
    • (2007) Bioorg Med Chem Lett , vol.17 , pp. 2509-2514
    • Alcaro, S.1    Artese, A.2    Iley, J.N.3
  • 55
    • 77950638598 scopus 로고    scopus 로고
    • Rational design, synthesis, biophysical and antiproliferative evaluation of fluorenone derivatives with DNA G-quadruplex binding properties
    • Alcaro S, Artese A, Iley JN, et al. Rational design, synthesis, biophysical and antiproliferative evaluation of fluorenone derivatives with DNA G-quadruplex binding properties. ChemMedChem 2010; 5: 575-583.
    • (2010) ChemMedChem , vol.5 , pp. 575-583
    • Alcaro, S.1    Artese, A.2    Iley, J.N.3
  • 56
    • 78650758700 scopus 로고    scopus 로고
    • S-Stereoisomer of telomestatin as a potent G-quadruplex binder and telomerase inhibitor
    • Doi T, Shibata K, Yoshida M, et al. S-Stereoisomer of telomestatin as a potent G-quadruplex binder and telomerase inhibitor. Org Biomol Chem 2011; 9: 387-393.
    • (2011) Org Biomol Chem , vol.9 , pp. 387-393
    • Doi, T.1    Shibata, K.2    Yoshida, M.3
  • 57
    • 0000159701 scopus 로고    scopus 로고
    • A quasi-flexible automatic docking processing for studying stereoselective recognition mechanisms. Part I. Protocol validation
    • Alcaro S, Gasparrini F, Incani O, Mecucci S, Misiti D, Pierini M, Villani C. A quasi-flexible automatic docking processing for studying stereoselective recognition mechanisms. Part I. Protocol validation. J Comput Chem 2000; 21: 515-530.
    • (2000) J Comput Chem , vol.21 , pp. 515-530
    • Alcaro, S.1    Gasparrini, F.2    Incani, O.3    Mecucci, S.4    Misiti, D.5    Pierini, M.6    Villani, C.7
  • 58
    • 33947721572 scopus 로고    scopus 로고
    • Quasi flexible automatic docking processing for studying stereoselective recognition mechanisms, part 2: Prediction of Delta Delta G of complexation and H1-NMR NOE correlation
    • Alcaro S, Gasparrini F, Incani O, Caglioti L, Pierini M, Villani C. Quasi flexible automatic docking processing for studying stereoselective recognition mechanisms, part 2: Prediction of Delta Delta G of complexation and H1-NMR NOE correlation. J Comput Chem 2007; 28: 1119-1128.
    • (2007) J Comput Chem , vol.28 , pp. 1119-1128
    • Alcaro, S.1    Gasparrini, F.2    Incani, O.3    Caglioti, L.4    Pierini, M.5    Villani, C.6
  • 59
    • 11644261806 scopus 로고    scopus 로고
    • Automated docking using a Lamarckian genetic algorithm and an empirical binding free energy function
    • Morris GM, Goodsell DS, Halliday RS, et al. Automated docking using a Lamarckian genetic algorithm and an empirical binding free energy function. J Comput Chem 1998; 19: 1639-1662.
    • (1998) J Comput Chem , vol.19 , pp. 1639-1662
    • Morris, G.M.1    Goodsell, D.S.2    Halliday, R.S.3
  • 60
    • 0037427245 scopus 로고    scopus 로고
    • Structure of the first parallel DNA quadruplex-drug complex
    • Clark GR, Pytel PD, Squire CJ, Neidle S. Structure of the first parallel DNA quadruplex-drug complex. J Am Chem Soc 2003; 125: 4066-4067.
    • (2003) J Am Chem Soc , vol.125 , pp. 4066-4067
    • Clark, G.R.1    Pytel, P.D.2    Squire, C.J.3    Neidle, S.4
  • 63
    • 84986437005 scopus 로고
    • Macromodel-an integrated software system for modeling organic and bioorganic molecules using molecular mechanics
    • Mohamadi F, Richards NGJ, Guida WC, et al. Macromodel-an integrated software system for modeling organic and bioorganic molecules using molecular mechanics. J Comput Chem 1990; 11: 440-467.
    • (1990) J Comput Chem , vol.11 , pp. 440-467
    • Mohamadi, F.1    Richards, N.G.J.2    Guida, W.C.3
  • 64
    • 0026620007 scopus 로고
    • AMBER torsional parameters for the peptide backbone
    • McDonald DQ, Still WC. AMBER torsional parameters for the peptide backbone. Tetrahedron Lett 1992; 33: 7743-7746.
    • (1992) Tetrahedron Lett , vol.33 , pp. 7743-7746
    • McDonald, D.Q.1    Still, W.C.2
  • 65
    • 0344778061 scopus 로고
    • Semianalytical treatment of solvation for molecular mechanics and dynamics
    • Still C, Tempczyk A, Hawley R, Hendrickson T. Semianalytical treatment of solvation for molecular mechanics and dynamics. J Am Chem Soc 1990; 112: 6127-6129.
    • (1990) J Am Chem Soc , vol.112 , pp. 6127-6129
    • Still, C.1    Tempczyk, A.2    Hawley, R.3    Hendrickson, T.4
  • 67
    • 44349142304 scopus 로고    scopus 로고
    • Structural basis of DNA quadruplex recognition by an acridine drug
    • Campbell NH, Parkinson GN, Reszka AP, Neidle S. Structural basis of DNA quadruplex recognition by an acridine drug. J Am Chem Soc 2008; 130: 6722-6724.
    • (2008) J Am Chem Soc , vol.130 , pp. 6722-6724
    • Campbell, N.H.1    Parkinson, G.N.2    Reszka, A.P.3    Neidle, S.4
  • 68
    • 34547562328 scopus 로고    scopus 로고
    • G-Quadruplex recognition by quinacridines: A SAR, NMR, and biological study
    • Hounsou C, Guittat L, Monchaud D, et al. G-Quadruplex recognition by quinacridines: a SAR, NMR, and biological study. ChemMedChem 2007; 2: 655-666.
    • (2007) ChemMedChem , vol.2 , pp. 655-666
    • Hounsou, C.1    Guittat, L.2    Monchaud, D.3


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