1,25-dihydroxyvitamin D3-3-bromoacetate, a novel vitamin D analog induces immunosuppression through PI3K/Akt/mTOR signaling cascade

International Immunopharmacology

Volumn 17, Issue 3, 2013, Pages 744-751

  Datta Mitra, Ananya ^a,b   Mitra, Anupam ^a,b   Ray, Rahul ^c   Raychaudhuri, Siba P ^a,b   Kundu Raychaudhuri, Smriti ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b VA Sacramento Medical Centre   (United States)

^c BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

1 ,25 dihydroxyvitamin D3 3 bromoacetate; Akt mTOR; Proliferation; T cells

Indexed keywords

1,25 DIHYDROXYVITAMIN D3 3 BROMOACETATE; 3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; CALCITRIOL; CARBOXYFLUORESCEIN DIACETATE SUCCINIMIDYL ESTER; CD3 ANTIGEN; CD4 ANTIGEN; CD8 ANTIGEN; LIPOCORTIN 5; MAMMALIAN TARGET OF RAPAMYCIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; UNCLASSIFIED DRUG; VITAMIN D DERIVATIVE;

ANTIPROLIFERATIVE ACTIVITY; APOPTOSIS; ARTICLE; CELL ACTIVATION; CELL PROLIFERATION; CELL STIMULATION; CONTROLLED STUDY; DILUTION; DRUG EFFECT; DRUG MECHANISM; DRUG POTENCY; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IMMUNOSUPPRESSIVE TREATMENT; INHIBITION KINETICS; INTRACELLULAR SIGNALING; LABORATORY; MEMORY T LYMPHOCYTE; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PSORIASIS; RHEUMATOID ARTHRITIS; T CELL CULTURE; T LYMPHOCYTE;

1Α,25-DIHYDROXYVITAMIN D3-3-BROMOACETATE; AKT/MTOR; PROLIFERATION; T CELLS;

ANTIGENS, CD3; APOPTOSIS; ARTHRITIS, RHEUMATOID; CALCITRIOL; CELL PROLIFERATION; CELLS, CULTURED; HUMANS; IMMUNOSUPPRESSION; IMMUNOSUPPRESSIVE AGENTS; LEUKOCYTES, MONONUCLEAR; PHOSPHATIDYLINOSITOL 3-KINASES; PROTO-ONCOGENE PROTEINS C-AKT; PSORIASIS; SIGNAL TRANSDUCTION; T-LYMPHOCYTES; TOR SERINE-THREONINE KINASES;

EID: 84884476877     PISSN: 15675769     EISSN: 18781705     Source Type: Journal    
DOI: 10.1016/j.intimp.2013.08.009     Document Type: Article

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