메뉴 건너뛰기




Volumn 22, Issue 4, 2011, Pages 160-168

Cytokine network in psoriasis revisited

Author keywords

Cytokine; Interleukin; Psoriasis; Th1; Th17; Th2

Indexed keywords

CYTOKINE; GAMMA INTERFERON; INTERLEUKIN 12; INTERLEUKIN 13; INTERLEUKIN 15; INTERLEUKIN 17; INTERLEUKIN 17F; INTERLEUKIN 2; INTERLEUKIN 20; INTERLEUKIN 22; INTERLEUKIN 23; INTERLEUKIN 26; INTERLEUKIN 4; INTERLEUKIN 5; INTERLEUKIN 6; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA;

EID: 84857002192     PISSN: 11485493     EISSN: None     Source Type: Journal    
DOI: 10.1684/ecn.2011.0294     Document Type: Review
Times cited : (84)

References (136)
  • 1
    • 36549035222 scopus 로고    scopus 로고
    • Immune regulation in psoriasis and psori-atic arthritis-recent developments
    • Hueber AJ, McInnes IB. Immune regulation in psoriasis and psori-atic arthritis-recent developments. Immunol Lett 2007; 114: 59-65.
    • (2007) Immunol Lett , vol.114 , pp. 59-65
    • Hueber, A.J.1    McInnes, I.B.2
  • 2
    • 77956498691 scopus 로고    scopus 로고
    • From benchtobedside-translational researchinpsoriasis
    • Prinz JC. From benchtobedside-translational researchinpsoriasis. JEADV 2010; 24: 1-4.
    • (2010) JEADV , vol.24 , pp. 1-4
    • Prinz, J.C.1
  • 3
    • 37249004404 scopus 로고    scopus 로고
    • The risk of mortality in patients with psoriasis: Results from a population-based study
    • Gelfand JM, Troxel AB, Lewis JD et al. The risk of mortality in patients with psoriasis: results from a population-based study. Arch Dermatol 2007; 143: 1493-1499.
    • (2007) Arch Dermatol , vol.143 , pp. 1493-1499
    • Gelfand, J.M.1    Troxel, A.B.2    Lewis, J.D.3
  • 4
    • 76749141832 scopus 로고    scopus 로고
    • Progress in understanding the immunopathogenesis of psoriasis
    • Mak RKH, Hundhausen C, Nestle FO. Progress in understanding the immunopathogenesis of psoriasis. Actas Dermosifiliogr 2009; 100: 2-13.
    • (2009) Actas Dermosifiliogr , vol.100 , pp. 2-13
    • Mak, R.K.H.1    Hundhausen, C.2    Nestle, F.O.3
  • 5
    • 77951091571 scopus 로고    scopus 로고
    • Circulating Th17, Th22, and Th1 Cells Are Increased in Psoriasis
    • Kagami S, Rizzo HL, Lee JJ et al. Circulating Th17, Th22, and Th1 Cells Are Increased in Psoriasis. J Invest Dermatol 2010; 130: 1373-1383.
    • (2010) J Invest Dermatol , vol.130 , pp. 1373-1383
    • Kagami, S.1    Rizzo, H.L.2    Lee, J.J.3
  • 6
    • 67651154105 scopus 로고    scopus 로고
    • Production of interleukin 22 but not interleukin 17 by a subset of human skin-homing memory T cells
    • Duhen T, Geiger R, Jarrossay D et al. Production of interleukin 22 but not interleukin 17 by a subset of human skin-homing memory T cells. Nat Immunol 2009; 10: 857-863.
    • (2009) Nat Immunol , vol.10 , pp. 857-863
    • Duhen, T.1    Geiger, R.2    Jarrossay, D.3
  • 7
    • 67649562339 scopus 로고    scopus 로고
    • Memory IL-22-producing CD4(+) T cells specific for Candida albicans are present in humans
    • Liu Y, Yang B, Zhou M et al. Memory IL-22-producing CD4(+) T cells specific for Candida albicans are present in humans. Eur J Immunol 2009; 39: 1472-1479.
    • (2009) Eur J Immunol , vol.39 , pp. 1472-1479
    • Liu, Y.1    Yang, B.2    Zhou, M.3
  • 8
    • 67651171182 scopus 로고    scopus 로고
    • Identificationofahuman helper T cell population that has abundant productionof interleukin22 and is distinct fromT(H)-17, T(H)1 and T(H)2 cells
    • Trifari S, Kaplan CD, Tran EH, et-al. Identificationofahuman helper T cell population that has abundant productionof interleukin22 and is distinct fromT(H)-17, T(H)1 and T(H)2 cells.Nat Immunol2009; 10: 864-871.
    • (2009) Nat Immunol , vol.10 , pp. 864-871
    • Trifari, S.1    Kaplan, C.D.2    Tran, E.H.3
  • 9
    • 55149087226 scopus 로고    scopus 로고
    • From interleukin-23toT-helper17cells: Human T-helper cell differentiation revisited
    • Boniface K, Blom B, Liu YJ, de Waal Malefyt R. From interleukin-23toT-helper17cells: human T-helper cell differentiation revisited. Immunol Rev 2008; 226: 132-146.
    • (2008) Immunol Rev , vol.226 , pp. 132-146
    • Boniface, K.1    Blom, B.2    Liu, Y.J.3    de Waal Malefyt, R.4
  • 10
    • 67349230808 scopus 로고    scopus 로고
    • The IL-23/Th17 Axis in the Immunopathogenesis of Psoriasis
    • Di Cesare A, Di Meglio P and Nestle FO. The IL-23/Th17 Axis in the Immunopathogenesis of Psoriasis. J Invest Dermatol 2009; 129: 1339-1350.
    • (2009) J Invest Dermatol , vol.129 , pp. 1339-1350
    • di Cesare, A.1    di Meglio, P.2    Nestle, F.O.3
  • 11
    • 38949155203 scopus 로고    scopus 로고
    • Regulation of IL-17 production in human lymphocytes
    • Chen Z, O'Shea JJ. Regulation of IL-17 production in human lymphocytes. Cytokine 2008; 41: 71-78.
    • (2008) Cytokine , vol.41 , pp. 71-78
    • Chen, Z.1    O'Shea, J.J.2
  • 12
    • 56549092012 scopus 로고    scopus 로고
    • Th17 cells: A new therapeutic targetininflammatory dermatoses
    • Asarch A, Barak O, Loo DS, Gottlieb AB. Th17 cells: A new therapeutic targetininflammatory dermatoses.J Dermatolog Treat2008; 19: 318-326.
    • (2008) J Dermatolog Treat , vol.19 , pp. 318-326
    • Asarch, A.1    Barak, O.2    Loo, D.S.3    Gottlieb, A.B.4
  • 13
    • 34250870891 scopus 로고    scopus 로고
    • TGF-beta(1) gene polymorphism in psoriasis vulgaris
    • Baran W, Szepietowski JC, Mazur G, Baran E. TGF-beta(1) gene polymorphism in psoriasis vulgaris. Cytokine 2007; 38: 8-11.
    • (2007) Cytokine , vol.38 , pp. 8-11
    • Baran, W.1    Szepietowski, J.C.2    Mazur, G.3    Baran, E.4
  • 14
    • 1942488905 scopus 로고    scopus 로고
    • Serum concentrations of transforming growth factor beta 1 in patients with psoriasis vulgaris
    • Nockowski P, Szepietowski JC, Ziarkiewicz M, Baran E. Serum concentrations of transforming growth factor beta 1 in patients with psoriasis vulgaris. Acta Dermatovenerol Croat 2004; 12: 2-6.
    • (2004) Acta Dermatovenerol Croat , vol.12 , pp. 2-6
    • Nockowski, P.1    Szepietowski, J.C.2    Ziarkiewicz, M.3    Baran, E.4
  • 15
    • 34248595506 scopus 로고    scopus 로고
    • T cells doing it for themselves: TGFbeta regulation of Th1 and Th17 cells
    • McGeachy MJ, Cua DJ. T cells doing it for themselves: TGFbeta regulation of Th1 and Th17 cells. Immunity 2007; 26: 547-549.
    • (2007) Immunity , vol.26 , pp. 547-549
    • McGeachy, M.J.1    Cua, D.J.2
  • 17
    • 0343019918 scopus 로고
    • Interleukin6isexpressed in high levels in psoriatic skin and stimulates proliferation of cultured human keratinocytes
    • Grossman RM, Krueger J, Yourish D et al. Interleukin6isexpressed in high levels in psoriatic skin and stimulates proliferation of cultured human keratinocytes. Proc Natl Acad Sci U S A 1989; 86: 6367-6371.
    • (1989) Proc Natl Acad Sci U S A , vol.86 , pp. 6367-6371
    • Grossman, R.M.1    Krueger, J.2    Yourish, D.3
  • 18
    • 24744454147 scopus 로고    scopus 로고
    • Human T cellsconstitutively express IL-15 that promotesexvivoTcell home-ostatic proliferation through autocrine/juxtacrine loops
    • Miranda-Carus ME, Benito-Miguel M, Llamas MA et al. Human T cellsconstitutively express IL-15 that promotesexvivoTcell home-ostatic proliferation through autocrine/juxtacrine loops. J Immunol 2005; 175: 3656-3662.
    • (2005) J Immunol , vol.175 , pp. 3656-3662
    • Miranda-Carus, M.E.1    Benito-Miguel, M.2    Llamas, M.A.3
  • 20
    • 3342897676 scopus 로고    scopus 로고
    • Interleukin-15: A new cytokine target for the treatment of inflammatory diseases
    • McInnes IB, Gracie JA. Interleukin-15: A new cytokine target for the treatment of inflammatory diseases. Curr Opin Pharmacol 2004; 4: 392-397.
    • (2004) Curr Opin Pharmacol , vol.4 , pp. 392-397
    • McInnes, I.B.1    Gracie, J.A.2
  • 21
    • 0346096722 scopus 로고    scopus 로고
    • Resolution of psoriasis upon blockade of IL-15 biological activity in a xenograft mouse model
    • Villadsen LS, Schuurman J, Beurskens F et al. Resolution of psoriasis upon blockade of IL-15 biological activity in a xenograft mouse model. J Clin Invest 2003; 112: 1571-1580.
    • (2003) J Clin Invest , vol.112 , pp. 1571-1580
    • Villadsen, L.S.1    Schuurman, J.2    Beurskens, F.3
  • 22
    • 79959255489 scopus 로고    scopus 로고
    • Th22 in inflammatory and autoimmune disease: Prospects for therapeutic intervention
    • Zhang N, Pan HF, Ye DQ. Th22 in inflammatory and autoimmune disease: prospects for therapeutic intervention. Mol Cell Biochem 2011; 353: 41-46.
    • (2011) Mol Cell Biochem , vol.353 , pp. 41-46
    • Zhang, N.1    Pan, H.F.2    Ye, D.Q.3
  • 23
    • 41649091472 scopus 로고    scopus 로고
    • Genes and structure of selected cytokines involved in pathogenesis of psoriasis
    • Pietrzak A, Zalewska A, Chodorowska G et al. Genes and structure of selected cytokines involved in pathogenesis of psoriasis. Folia Histochem Cytobiol 2008; 46: 11-21.
    • (2008) Folia Histochem Cytobiol , vol.46 , pp. 11-21
    • Pietrzak, A.1    Zalewska, A.2    Chodorowska, G.3
  • 24
    • 0027405991 scopus 로고
    • The IL-2 receptor complex: Its structure, function, and target genes
    • Minami Y, Kono T, Miyazaki T, Taniguchi T. The IL-2 receptor complex: its structure, function, and target genes. Annu Rev Immunol 1993; 11: 245-267.
    • (1993) Annu Rev Immunol , vol.11 , pp. 245-267
    • Minami, Y.1    Kono, T.2    Miyazaki, T.3    Taniguchi, T.4
  • 27
    • 0242550855 scopus 로고    scopus 로고
    • Pruritogenicmediators in psoriasis vulgaris: Comparative evaluation of itch-associated cutaneous factors
    • Nakamura M, Toyoda M, Morohashi M. Pruritogenicmediators in psoriasis vulgaris: comparative evaluation of itch-associated cutaneous factors. Br J Dermatol 2003; 149: 718-730.
    • (2003) Br J Dermatol , vol.149 , pp. 718-730
    • Nakamura, M.1    Toyoda, M.2    Morohashi, M.3
  • 28
    • 8344269413 scopus 로고    scopus 로고
    • Association of cyclosporine and 311 nM UVB in the treatment of moderate to severe forms of psoriasis: A new strategic approach
    • Franchi C, Cainelli G et al. Association of cyclosporine and 311 nM UVB in the treatment of moderate to severe forms of psoriasis: a new strategic approach. Int JImmunopathol Pharmacol 2004; 17: 401-406.
    • (2004) Int JImmunopathol Pharmacol , vol.17 , pp. 401-406
    • Franchi, C.1    Cainelli, G.2
  • 30
    • 58149316658 scopus 로고    scopus 로고
    • Induction of IL-17+ T cell trafficking and development by IFN-gamma: Mechanism and pathological relevance in psoriasis
    • Kryczek I, Bruce AT, Gudjonsson JE, et al. Induction of IL-17+ T cell trafficking and development by IFN-gamma: mechanism and pathological relevance in psoriasis. J Immunol 2008; 181: 4733-4741.
    • (2008) J Immunol , vol.181 , pp. 4733-4741
    • Kryczek, I.1    Bruce, A.T.2    Gudjonsson, J.E.3
  • 31
    • 70349753261 scopus 로고    scopus 로고
    • Th17 Cytokines Stimulate CCL20 Expression in Keratinocytes In Vitro and In Vivo: Implications for Psoriasis Pathogenesis
    • Harper EG, Guo CH, Rizzo H et al. Th17 Cytokines Stimulate CCL20 Expression in Keratinocytes In Vitro and In Vivo: Implications for Psoriasis Pathogenesis. J Invest Dermatol 2009; 129: 2175-2183.
    • (2009) J Invest Dermatol , vol.129 , pp. 2175-2183
    • Harper, E.G.1    Guo, C.H.2    Rizzo, H.3
  • 32
    • 34547734621 scopus 로고    scopus 로고
    • Phenotypic and functional features of human Th17 cells
    • Annunziato F, Cosmi L, Santarlasci V et al. Phenotypic and functional features of human Th17 cells. JExpMed2007; 204:1849-61.
    • (2007) J. Exp. Med , vol.204 , pp. 1849-1861
    • Annunziato, F.1    Cosmi, L.2    Santarlasci, V.3
  • 33
    • 34548133583 scopus 로고    scopus 로고
    • Development, cytokine profile and function of human interleukin 17-producing helper T cells
    • Wilson NJ, Boniface K, Chan JR, et al. Development, cytokine profile and function of human interleukin 17-producing helper T cells. Nat Immunol 2007; 8: 950-957.
    • (2007) Nat Immunol , vol.8 , pp. 950-957
    • Wilson, N.J.1    Boniface, K.2    Chan, J.R.3
  • 34
    • 0029900486 scopus 로고    scopus 로고
    • Differentiation of human keratinocytes is associated with a progressive loss of interferon--y-induced intercellular adhesion molecule 1 expression
    • Little MC, Gawkrodger DJ, Mac Neil S. Differentiation of human keratinocytes is associated with a progressive loss of interferon--y-induced intercellular adhesion molecule 1 expression. Br J Dermatol 1996; 135: 24-31.
    • (1996) Br J Dermatol , vol.135 , pp. 24-31
    • Little, M.C.1    Gawkrodger, D.J.2    Mac Neil, S.3
  • 35
    • 0037403907 scopus 로고    scopus 로고
    • Elevated rate of Thelper1 (TH1) lymphocytes and serum IFN--y levels in psoriatic patients
    • Szegedi A, Aleksza M, Gonda A et al. Elevated rate of Thelper1 (TH1) lymphocytes and serum IFN--y levels in psoriatic patients. Immunol Lett 2003; 86: 277-280.
    • (2003) Immunol Lett , vol.86 , pp. 277-280
    • Szegedi, A.1    Aleksza, M.2    Gonda, A.3
  • 36
    • 79955378160 scopus 로고    scopus 로고
    • Serum levels of interleukin-8, tumor necrosis factor-a and -y-interferon in Egyptian psoriatic patients and correlation with disease severity
    • Abdel-Hamid MF, Aly DG, Saad NE et al. Serum levels of interleukin-8, tumor necrosis factor-a and -y-interferon in Egyptian psoriatic patients and correlation with disease severity. J Dermatol 2011; 38: 442-446.
    • (2011) J Dermatol , vol.38 , pp. 442-446
    • Abdel-Hamid, M.F.1    Aly, D.G.2    Saad, N.E.3
  • 37
    • 0031883245 scopus 로고    scopus 로고
    • Plasma concentrations of IFN--y and TNF-a in psoriatic patients before and after local treatment with dithranol ointment
    • Chodorowska G. Plasma concentrations of IFN--y and TNF-a in psoriatic patients before and after local treatment with dithranol ointment. J Eur Acad Dermatol Venereol 1998; 10: 147-151.
    • (1998) J Eur Acad Dermatol Venereol , vol.10 , pp. 147-151
    • Chodorowska, G.1
  • 38
    • 0032729645 scopus 로고    scopus 로고
    • The majority of epidermal T cells in Psoriasis vulgaris lesions can produce type 1 cytokines, interferon-gamma, interleukin-2, and tumor necrosis factor-alpha, defining TC1 (cytotoxic T lymphocyte) and TH1 effector populations: A type 1 differentiation bias is also measured in circulating blood T cells in psoriatic patients
    • Austin LM, Ozawa M, Kikuchi T et al. The majority of epidermal T cells in Psoriasis vulgaris lesions can produce type 1 cytokines, interferon-gamma, interleukin-2, and tumor necrosis factor-alpha, defining TC1 (cytotoxic T lymphocyte) and TH1 effector populations: a type 1 differentiation bias is also measured in circulating blood T cells in psoriatic patients. J Invest Dermatol 1999; 113: 752-759.
    • (1999) J Invest Dermatol , vol.113 , pp. 752-759
    • Austin, L.M.1    Ozawa, M.2    Kikuchi, T.3
  • 39
    • 0037453146 scopus 로고    scopus 로고
    • Novel mechanisms of T-cell and dendritic cell activation revealed by profiling of psoriasis on the 63,100-element oligonucleotide array
    • Zhou X, Krueger JG, Kao MC et al. Novel mechanisms of T-cell and dendritic cell activation revealed by profiling of psoriasis on the 63,100-element oligonucleotide array. Physiol Genomics 2003; 13: 69-78.
    • (2003) Physiol Genomics , vol.13 , pp. 69-78
    • Zhou, X.1    Krueger, J.G.2    Kao, M.C.3
  • 40
    • 0027439191 scopus 로고
    • The cytokine network in lesional and lesion-free psoriatic skin is characterized by a T-helpertype 1 cell-mediated response
    • Uyemura K, Yamamura M, Fivenson DF et al. The cytokine network in lesional and lesion-free psoriatic skin is characterized by a T-helpertype 1 cell-mediated response. J Invest Dermatol 1993; 101: 701-705.
    • (1993) J Invest Dermatol , vol.101 , pp. 701-705
    • Uyemura, K.1    Yamamura, M.2    Fivenson, D.F.3
  • 42
    • 79957524037 scopus 로고    scopus 로고
    • Systemic pho-tochemotherapy decreases the expression of IFN--y, IL-12p40 and IL-23p19 in psoriatic plaques
    • Ravic-Nikolic A, Radosavljevic G, Jovanovic I et al. Systemic pho-tochemotherapy decreases the expression of IFN--y, IL-12p40 and IL-23p19 in psoriatic plaques. Eur J Dermatol 2011; 21: 53-57.
    • (2011) Eur J Dermatol , vol.21 , pp. 53-57
    • Ravic-Nikolic, A.1    Radosavljevic, G.2    Jovanovic, I.3
  • 44
    • 2442443310 scopus 로고    scopus 로고
    • Biology of tumor necrosis factor-a - implications for psoriasis
    • Schottelius AJG, Moldawer LL, Dinarello CA et al. Biology of tumor necrosis factor-a - implications for psoriasis. Exp Dermatol 2004; 13: 193-222.
    • (2004) Exp Dermatol , vol.13 , pp. 193-222
    • Schottelius, A.J.G.1    Moldawer, L.L.2    Dinarello, C.A.3
  • 46
    • 0031658289 scopus 로고    scopus 로고
    • Tumor necrosis factor locus: Genetic organisation and biological implications
    • Makhatadze NJ. Tumor necrosis factor locus: genetic organisation and biological implications. Human Immunol 1998; 59: 571-579.
    • (1998) Human Immunol , vol.59 , pp. 571-579
    • Makhatadze, N.J.1
  • 47
    • 0029928366 scopus 로고    scopus 로고
    • Tumor necrosis factors: Developments during the last decade
    • Aggarwal BB, Natarajan K. Tumor necrosis factors: developments during the last decade. Eur Cytokine Netw 1996; 7: 93-124.
    • (1996) Eur Cytokine Netw , vol.7 , pp. 93-124
    • Aggarwal, B.B.1    Natarajan, K.2
  • 48
    • 0028901436 scopus 로고
    • Tumor necrosis factor alpha is pro-inflammatory in normal human skin and modulates cutaneous adhesion molecule expression
    • Groves RW, Allen MH, Ross EL et al. Tumor necrosis factor alpha is pro-inflammatory in normal human skin and modulates cutaneous adhesion molecule expression. Br J Dermatol 1995; 132: 345-352.
    • (1995) Br J Dermatol , vol.132 , pp. 345-352
    • Groves, R.W.1    Allen, M.H.2    Ross, E.L.3
  • 49
    • 37549011317 scopus 로고    scopus 로고
    • Amelioration of epidermal hyperplasia by TNF inhibition is associated with reduced Th17 responses
    • Zaba LC, Cardinale I, Gilleaudeau P et al. Amelioration of epidermal hyperplasia by TNF inhibition is associated with reduced Th17 responses. J Exp Med. 2007; 204: 3183-3194.
    • (2007) J Exp Med , vol.204 , pp. 3183-3194
    • Zaba, L.C.1    Cardinale, I.2    Gilleaudeau, P.3
  • 50
    • 23444432216 scopus 로고    scopus 로고
    • TNF inhibition rapidly down-regulates multiple proinflammatory pathways in psoriasis plaques
    • Gottlieb AB, Chamian F, Masud S et al. TNF inhibition rapidly down-regulates multiple proinflammatory pathways in psoriasis plaques. J Immunol 2005; 175: 2721-2729.
    • (2005) J Immunol , vol.175 , pp. 2721-2729
    • Gottlieb, A.B.1    Chamian, F.2    Masud, S.3
  • 51
    • 34548618728 scopus 로고    scopus 로고
    • TNF-alpha drives human CD14+ monocytes to differentiate into CD70+ dendritic cells evoking Th1 and Th17 responses
    • Iwamoto S, Iwai S, Tsujiyama K et al. TNF-alpha drives human CD14+ monocytes to differentiate into CD70+ dendritic cells evoking Th1 and Th17 responses. J Immunol 2007; 179: 1449-1457.
    • (2007) J Immunol , vol.179 , pp. 1449-1457
    • Iwamoto, S.1    Iwai, S.2    Tsujiyama, K.3
  • 52
    • 0028001146 scopus 로고
    • Correlated increases of tumour necrosis factor-a, interleukin-6 and granulocyte monocyte - colony stimulating factor levels in suction blister fluids and sera of psoriatic patients - relationship with disease severity
    • Bonifati C, Carducci M, Cordiali Fei P et al. Correlated increases of tumour necrosis factor-a, interleukin-6 and granulocyte monocyte - colony stimulating factor levels in suction blister fluids and sera of psoriatic patients - relationship with disease severity. Clin Exp Dermatol 1994; 19: 383-387.
    • (1994) Clin Exp Dermatol , vol.19 , pp. 383-387
    • Bonifati, C.1    Carducci, M.2    Cordiali Fei, P.3
  • 53
    • 0028233818 scopus 로고
    • Elevated tumour necrosis factor-alpha (TNF) biological activity in psoriatic skin lesions
    • Ettehadi P, Greaves MW, Wallach D et al. Elevated tumour necrosis factor-alpha (TNF) biological activity in psoriatic skin lesions. Clin Exp Immunol 1994; 96: 146-151.
    • (1994) Clin Exp Immunol , vol.96 , pp. 146-151
    • Ettehadi, P.1    Greaves, M.W.2    Wallach, D.3
  • 54
    • 0027490541 scopus 로고
    • Localization of tumour necrosis factor-alpha (TNF-alpha) and its receptors in normal and psoriatic skin: Epidermal cells express the 55-kD but not the 75-kD TNF receptor
    • Kristensen M, Chu CQ, Eedy DJ et al. Localization of tumour necrosis factor-alpha (TNF-alpha) and its receptors in normal and psoriatic skin: epidermal cells express the 55-kD but not the 75-kD TNF receptor. Clin Exp Immunol 1993; 94: 354-362.
    • (1993) Clin Exp Immunol , vol.94 , pp. 354-362
    • Kristensen, M.1    Chu, C.Q.2    Eedy, D.J.3
  • 55
    • 0031469174 scopus 로고    scopus 로고
    • Serum TNF-alpha levels correlate with disease severity and are reduced by effective therapy in plaque-type psoriasis
    • Mussi A, Bonifati C, Carducci M et al. Serum TNF-alpha levels correlate with disease severity and are reduced by effective therapy in plaque-type psoriasis. J Biol Regul Homeost Agents 1997; 11: 115-118.
    • (1997) J Biol Regul Homeost Agents , vol.11 , pp. 115-118
    • Mussi, A.1    Bonifati, C.2    Carducci, M.3
  • 56
    • 0031080905 scopus 로고    scopus 로고
    • Role of increased production of monocytes TNF-a, IL-1 fj and IL-6 in psoriasis: Relation to focal infection, disease activity and responses to treatments
    • Mizutani H, Ohmoto Y, Mizutani T et al. Role of increased production of monocytes TNF-a, IL-1 fj and IL-6 in psoriasis: relation to focal infection, disease activity and responses to treatments. J Dermatol Sci 1997; 14: 145-153.
    • (1997) J Dermatol Sci , vol.14 , pp. 145-153
    • Mizutani, H.1    Ohmoto, Y.2    Mizutani, T.3
  • 57
    • 0028233818 scopus 로고
    • Elevated tumour necrosis factor-alpha (TNF) biological activity in psoriatic skin lesions
    • Ettehadi P, Greaves MW, Wallach D et al. Elevated tumour necrosis factor-alpha (TNF) biological activity in psoriatic skin lesions. Clin Exp Immunol 1994; 96: 146-151.
    • (1994) Clin Exp Immunol , vol.96 , pp. 146-151
    • Ettehadi, P.1    Greaves, M.W.2    Wallach, D.3
  • 58
    • 0029788122 scopus 로고    scopus 로고
    • Cytokine expression in psoriatic skin lesions during PUVA therapy
    • Olaniran AK, Baker BS, Paige DG et al. Cytokine expression in psoriatic skin lesions during PUVA therapy. Arch Dermatol Res 1996; 288: 421-425.
    • (1996) Arch Dermatol Res , vol.288 , pp. 421-425
    • Olaniran, A.K.1    Baker, B.S.2    Paige, D.G.3
  • 59
    • 0028310481 scopus 로고
    • Serum levels of interferons and TNF-a are not correlated to psoriasis activity and therapy
    • Tigalonova M, Bjerke JR, Gallati H et al. Serum levels of interferons and TNF-a are not correlated to psoriasis activity and therapy. Acta Derm Venereol 1994; 186: 25-27.
    • (1994) Acta Derm Venereol , vol.186 , pp. 25-27
    • Tigalonova, M.1    Bjerke, J.R.2    Gallati, H.3
  • 60
    • 37049004419 scopus 로고    scopus 로고
    • Recent advances in Psoriasis Therapy and the Work of the International Psoriasis Council
    • Menter A. Recent advances in Psoriasis Therapy and the Work of the International Psoriasis Council. US Derm Review 2006; 1: 23-27.
    • (2006) US Derm Review , vol.1 , pp. 23-27
    • Menter, A.1
  • 61
    • 33847206969 scopus 로고    scopus 로고
    • IL-17 family cytokines and the expanding diversity of effector T cell lineages
    • Weaver CT, Hatton RD, Mangan PR, Harrington LE. IL-17 family cytokines and the expanding diversity of effector T cell lineages. Annu Rev Immunol 2007; 25: 821-852.
    • (2007) Annu Rev Immunol , vol.25 , pp. 821-852
    • Weaver, C.T.1    Hatton, R.D.2    Mangan, P.R.3    Harrington, L.E.4
  • 62
    • 0028858556 scopus 로고
    • Human IL-17: A novel cytokine derived from T cells
    • Yao Z et al. Human IL-17: a novel cytokine derived from T cells. J Immunol 1995; 155: 5483-5486.
    • (1995) J Immunol , vol.155 , pp. 5483-5486
    • Yao, Z.1
  • 63
    • 67349234068 scopus 로고    scopus 로고
    • IL-17 and Th17 cells in human inflammatory diseases
    • Miossec P. IL-17 and Th17 cells in human inflammatory diseases. Microbes and Infection 2009; 11: 625-630.
    • (2009) Microbes and Infection , vol.11 , pp. 625-630
    • Miossec, P.1
  • 64
    • 0033119051 scopus 로고    scopus 로고
    • Expression of IL-17 in human memory CD45RO+ T lymphocytes and its regulation by protein kinase A pathway
    • Shin HC, Benbernou N, Esnault S, Guenounou M. Expression of IL-17 in human memory CD45RO+ T lymphocytes and its regulation by protein kinase A pathway. Cytokine 1999; 11: 257-266.
    • (1999) Cytokine , vol.11 , pp. 257-266
    • Shin, H.C.1    Benbernou, N.2    Esnault, S.3    Guenounou, M.4
  • 66
    • 42149161160 scopus 로고    scopus 로고
    • T-Helper 17 Cells in Psoriatic Plaques and Additional Genetic Links between IL-23 and Psoriasis
    • Blauvelt A. T-Helper 17 Cells in Psoriatic Plaques and Additional Genetic Links between IL-23 and Psoriasis. J Invest Dermatol 2008; 128: 1064-1067.
    • (2008) J Invest Dermatol , vol.128 , pp. 1064-1067
    • Blauvelt, A.1
  • 67
    • 33749138039 scopus 로고    scopus 로고
    • IL-17 production is dominated by gammadelta T cells rather than CD4 T cells during Mycobacterium tuberculosis infection
    • Lockhart E, Green AM, Flynn JL. IL-17 production is dominated by gammadelta T cells rather than CD4 T cells during Mycobacterium tuberculosis infection. J Immunol 2006; 177: 4662-4669.
    • (2006) J Immunol , vol.177 , pp. 4662-4669
    • Lockhart, E.1    Green, A.M.2    Flynn, J.L.3
  • 68
    • 38049072274 scopus 로고    scopus 로고
    • Langerhans cell histiocytosis reveals a new IL-17A-dependent pathway of dendritic cell fusion
    • Coury F, Annels N, Rivollier A et al. Langerhans cell histiocytosis reveals a new IL-17A-dependent pathway of dendritic cell fusion. Nat Med 2008; 4: 81-87.
    • (2008) Nat Med , vol.4 , pp. 81-87
    • Coury, F.1    Annels, N.2    Rivollier, A.3
  • 69
    • 34249059942 scopus 로고    scopus 로고
    • Identification of an IL-17-producing NK1.1(neg) iNKT cell population involved in airway neutrophilia
    • Michel ML, Keller AC, Paget C et al. Identification of an IL-17-producing NK1.1(neg) iNKT cell population involved in airway neutrophilia. J Exp Med 2007; 204: 995-1001.
    • (2007) J Exp Med , vol.204 , pp. 995-1001
    • Michel, M.L.1    Keller, A.C.2    Paget, C.3
  • 70
    • 42649110747 scopus 로고    scopus 로고
    • Cutting edge: NKT cells constitutively express IL-23 receptor and RORgammat and rapidly produce IL-17 upon receptor ligation in an IL-6-independent fashion
    • Rachitskaya AV, Hansen AM, Horai R et al. Cutting edge: NKT cells constitutively express IL-23 receptor and RORgammat and rapidly produce IL-17 upon receptor ligation in an IL-6-independent fashion. J Immunol 2008; 180: 5167-5171.
    • (2008) J Immunol , vol.180 , pp. 5167-5171
    • Rachitskaya, A.V.1    Hansen, A.M.2    Horai, R.3
  • 71
    • 79959525322 scopus 로고    scopus 로고
    • Rutledge. A tale of two plaques: Convergent mechanisms of T-cell-mediated inflammation in psoriasis and atherosclerosis
    • Armstrong AW, Voyles SV, Armstrong EJ et al. Rutledge. A tale of two plaques: convergent mechanisms of T-cell-mediated inflammation in psoriasis and atherosclerosis. Exp Dermatol 2011; 20: 544-549.
    • (2011) Exp Dermatol , vol.20 , pp. 544-549
    • Armstrong, A.W.1    Voyles, S.V.2    Armstrong, E.J.3
  • 72
    • 34249079176 scopus 로고    scopus 로고
    • Surface pheno-type and antigenic specificity of human interleukin 17-producing T helper memory cells
    • Acosta-Rodriguez EV, Rivino L, Geginat J et al. Surface pheno-type and antigenic specificity of human interleukin 17-producing T helper memory cells. Nat Immunol 2007; 8: 639-646.
    • (2007) Nat Immunol , vol.8 , pp. 639-646
    • Acosta-Rodriguez, E.V.1    Rivino, L.2    Geginat, J.3
  • 73
    • 46049099979 scopus 로고    scopus 로고
    • Human Th17 Cell Clones and Natural Immune Responses
    • Matsushita S, Higashi T. Human Th17 Cell Clones and Natural Immune Responses. Allergol Int 2008; 57: 135-140.
    • (2008) Allergol Int , vol.57 , pp. 135-140
    • Matsushita, S.1    Higashi, T.2
  • 74
    • 36549019912 scopus 로고    scopus 로고
    • Preferential recruitment of CCR6-expressing Th17 cells to inflamed joints via CCL20 in rheumatoid arthritis and its Animals model
    • Hirota K, Yoshitomi H, Hashimoto M et al. Preferential recruitment of CCR6-expressing Th17 cells to inflamed joints via CCL20 in rheumatoid arthritis and its Animals model. J Exp Med 2007; 204: 2803-2812.
    • (2007) J Exp Med , vol.204 , pp. 2803-2812
    • Hirota, K.1    Yoshitomi, H.2    Hashimoto, M.3
  • 76
    • 35348915412 scopus 로고    scopus 로고
    • IL-23 and the Th17 pathway promote inflammation and impair antifungal immune resistance
    • Zelante T et al. IL-23 and the Th17 pathway promote inflammation and impair antifungal immune resistance. Eur J Immunol 2007; 37: 2695-2706.
    • (2007) Eur J Immunol , vol.37 , pp. 2695-2706
    • Zelante, T.1
  • 77
    • 42149087160 scopus 로고    scopus 로고
    • Psoriasis vulgaris lesions contain discrete populations of Th1 and Th17 T Cells
    • Lowes MA, Kikuchi T, Fuentes-Duculan J et al. Psoriasis vulgaris lesions contain discrete populations of Th1 and Th17 T Cells. J Invest Dermatol 2008; 128: 1207-1211.
    • (2008) J Invest Dermatol , vol.128 , pp. 1207-1211
    • Lowes, M.A.1    Kikuchi, T.2    Fuentes-Duculan, J.3
  • 78
    • 33646552450 scopus 로고    scopus 로고
    • IL-22 regulates the expression of genes responsible for antimicrobial defense, cellular differentiation, and mobility in keratinocytes: A potential role in psoriasis
    • Wolk K, Witte E, Wallace E et al. IL-22 regulates the expression of genes responsible for antimicrobial defense, cellular differentiation, and mobility in keratinocytes: a potential role in psoriasis. Eur J Immunol 2006; 36: 1309-1323.
    • (2006) Eur J Immunol , vol.36 , pp. 1309-1323
    • Wolk, K.1    Witte, E.2    Wallace, E.3
  • 79
    • 49249135394 scopus 로고    scopus 로고
    • Human interleukin 17-producing cells originate from a CD161+CD4+ T cell precursor
    • Cosmi L, De Palma R, Santarlasci V et al. Human interleukin 17-producing cells originate from a CD161+CD4+ T cell precursor. J Exp Med 2008; 205: 1903-1916.
    • (2008) J Exp Med , vol.205 , pp. 1903-1916
    • Cosmi, L.1    de Palma, R.2    Santarlasci, V.3
  • 80
    • 33749318470 scopus 로고    scopus 로고
    • Interleukin (IL)-22 and IL-17 are coexpressed by Th17 cells and cooperatively enhance expression of antimicrobial peptides
    • Liang SC et al. Interleukin (IL)-22 and IL-17 are coexpressed by Th17 cells and cooperatively enhance expression of antimicrobial peptides. J Exp Med 2006; 203: 2271-2279.
    • (2006) J Exp Med , vol.203 , pp. 2271-2279
    • Liang, S.C.1
  • 81
    • 59649099774 scopus 로고    scopus 로고
    • A human natural killer cell subset provides an innate source of IL-22 for mucosal immunity
    • Cella X et al. A human natural killer cell subset provides an innate source of IL-22 for mucosal immunity. Nature 2009; 457:722-725.
    • (2009) Nature , vol.457 , pp. 722-725
    • Cella, X.1
  • 82
    • 67651154105 scopus 로고    scopus 로고
    • Production of interleukin 22 but not interleukin 17 by a subset of human skin-homing memory T cells
    • Duhen T, Geiger R, Jarrossay D et al. Production of interleukin 22 but not interleukin 17 by a subset of human skin-homing memory T cells. Nat Immunol 2009; 10: 857-863.
    • (2009) Nat Immunol , vol.10 , pp. 857-863
    • Duhen, T.1    Geiger, R.2    Jarrossay, D.3
  • 83
    • 67649562339 scopus 로고    scopus 로고
    • Memory IL-22-producing CD4(+) T cells specific for Candida albicans are present in humans
    • Liu Y, Yang B, Zhou M et al. Memory IL-22-producing CD4(+) T cells specific for Candida albicans are present in humans. Eur J Immunol 2009; 39: 1472-1479.
    • (2009) Eur J Immunol , vol.39 , pp. 1472-1479
    • Liu, Y.1    Yang, B.2    Zhou, M.3
  • 84
    • 79959700032 scopus 로고    scopus 로고
    • Research in practice: IL-22 and IL-20: Significance for epithelial homeostasis and psoriasis pathogenesis
    • 10.1111/j.1610-0387.2011.07611.x
    • Sabat R, Wolk K. Research in practice: IL-22 and IL-20: significance for epithelial homeostasis and psoriasis pathogenesis.J Dtsch Dermatol Ges 2011; doi: 10.1111/j.1610-0387.2011.07611.x.
    • (2011) J Dtsch Dermatol Ges
    • Sabat, R.1    Wolk, K.2
  • 85
    • 33749983749 scopus 로고    scopus 로고
    • Interleukin-22: A novel T and NK cell derived cytokine that regulates the biology of tissue cells
    • Wolk K, Sabat R. Interleukin-22: a novel T and NK cell derived cytokine that regulates the biology of tissue cells. Cytokine Growth Factor Rev 2006; 17: 367-380.
    • (2006) Cytokine Growth Factor Rev , vol.17 , pp. 367-380
    • Wolk, K.1    Sabat, R.2
  • 86
    • 67349275024 scopus 로고    scopus 로고
    • IL-22: A critical mediator in mucosal host defense
    • Aujla SJ, Kolls JK. IL-22: A critical mediator in mucosal host defense. J Mol Med 2009; 87: 451-454.
    • (2009) J Mol Med , vol.87 , pp. 451-454
    • Aujla, S.J.1    Kolls, J.K.2
  • 87
    • 14844342604 scopus 로고    scopus 로고
    • IL-22 inhibits epidermal differentiation and induces proinflammatory gene expression and migration of human keratinocytes
    • Boniface X et al. IL-22 inhibits epidermal differentiation and induces proinflammatory gene expression and migration of human keratinocytes. J Immunol 2005; 174: 3695-3702.
    • (2005) J Immunol , vol.174 , pp. 3695-3702
    • Boniface, X.1
  • 88
    • 40049083827 scopus 로고    scopus 로고
    • Interleukin 22 mediates early host defense against attaching and effacing bacterial pathogens
    • Zheng X et al. Interleukin 22 mediates early host defense against attaching and effacing bacterial pathogens. Nat Med 2008; 14: 282-289.
    • (2008) Nat Med , vol.14 , pp. 282-289
    • Zheng, X.1
  • 89
    • 24144477540 scopus 로고    scopus 로고
    • Interleukin-22, a member of the IL-10 subfamily, induces inflammatory responsesincolonic subepithelialmyofibrob-lasts
    • Andoh X et al. Interleukin-22, a member of the IL-10 subfamily, induces inflammatory responsesincolonic subepithelialmyofibrob-lasts. Gastroenterol 2005; 129: 969-984.
    • (2005) Gastroenterol , vol.129 , pp. 969-984
    • Andoh, X.1
  • 90
    • 36048953799 scopus 로고    scopus 로고
    • Arole forT cell-derived interleukin 22 in psoriatic skin inflammation
    • Boniface K, Guignouard E, Pedretti N, et al. Arole forT cell-derived interleukin 22 in psoriatic skin inflammation. Clin Exp Immunol 2007; 150: 407-415.
    • (2007) Clin Exp Immunol , vol.150 , pp. 407-415
    • Boniface, K.1    Guignouard, E.2    Pedretti, N.3
  • 91
    • 61849168497 scopus 로고    scopus 로고
    • Serum levels of IL-17 and IL-22 are reduced by Etanercept, but not by Acitretin, in patients with psoriasis: A randomized controlled trial
    • Caproni M, Antiga E, Melani L et al. Serum levels of IL-17 and IL-22 are reduced by Etanercept, but not by Acitretin, in patients with psoriasis: a randomized controlled trial. J Clin Immunol 2009; 29: 210-214.
    • (2009) J Clin Immunol , vol.29 , pp. 210-214
    • Caproni, M.1    Antiga, E.2    Melani, L.3
  • 92
    • 80052260255 scopus 로고    scopus 로고
    • Interleukin-22 downregulates filaggrin expression and affects expression of profilaggrin processing enzymes
    • Gutowska-Owsiak D, Schaupp AL, Salimi M et al. Interleukin-22 downregulates filaggrin expression and affects expression of profilaggrin processing enzymes. Br J Dermatol 2011; 165: 492-498.
    • (2011) Br J Dermatol , vol.165 , pp. 492-498
    • Gutowska-Owsiak, D.1    Schaupp, A.L.2    Salimi, M.3
  • 93
    • 79951587566 scopus 로고    scopus 로고
    • Psoriasis and other Th17-mediated skin diseases
    • Tokura Y, Mori T, Hino R. Psoriasis and other Th17-mediated skin diseases. J UOEH 2010; 32: 317-328.
    • (2010) J UOEH , vol.32 , pp. 317-328
    • Tokura, Y.1    Mori, T.2    Hino, R.3
  • 94
    • 72849131815 scopus 로고    scopus 로고
    • Th22 cells represent a distinct human T cell subset involved in epidermal immunity and remodeling
    • Eyerich S, Eyerich K, Pennino D et al. Th22 cells represent a distinct human T cell subset involved in epidermal immunity and remodeling. J Clin Invest 2009; 119: 3573-3585.
    • (2009) J Clin Invest , vol.119 , pp. 3573-3585
    • Eyerich, S.1    Eyerich, K.2    Pennino, D.3
  • 95
    • 70350547787 scopus 로고    scopus 로고
    • IL-17 and IL-22 mediate IL-20 subfamily cytokine production in cultured keratinocytes via increased IL-22 receptor expression
    • Tohyama M, Hanakawa Y, Shirakata Y et al. IL-17 and IL-22 mediate IL-20 subfamily cytokine production in cultured keratinocytes via increased IL-22 receptor expression. Eur J Immunol 2009; 39: 2779-2788.
    • (2009) Eur J Immunol , vol.39 , pp. 2779-2788
    • Tohyama, M.1    Hanakawa, Y.2    Shirakata, Y.3
  • 96
  • 97
    • 79953048089 scopus 로고    scopus 로고
    • Regulation and functions of the IL-10 family of cytokines in inflammation and disease
    • Ouyang W, Rutz S, Crellin NK et al. Regulation and functions of the IL-10 family of cytokines in inflammation and disease. Annu Rev Immunol 2011; 29: 71-109.
    • (2011) Annu Rev Immunol , vol.29 , pp. 71-109
    • Ouyang, W.1    Rutz, S.2    Crellin, N.K.3
  • 98
    • 0033638507 scopus 로고    scopus 로고
    • Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12
    • Oppmann B, Lesley R, Blom B et al. Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12. Immunity 2000; 13: 715-725.
    • (2000) Immunity , vol.13 , pp. 715-725
    • Oppmann, B.1    Lesley, R.2    Blom, B.3
  • 99
    • 79960776307 scopus 로고    scopus 로고
    • Interleukin-23: A key cytokine in inflammatory diseases
    • 10.3109/07853890.2011.577093
    • Duvallet E, Semerano L, Assier E et al. Interleukin-23: A key cytokine in inflammatory diseases. Ann Med 2011; doi: 10.3109/07853890.2011.577093.
    • (2011) Ann Med
    • Duvallet, E.1    Semerano, L.2    Assier, E.3
  • 100
    • 53149100445 scopus 로고    scopus 로고
    • Interleukin 23:Akey cytokinein chronic inflammatory disease
    • Wendling D. Interleukin 23:akey cytokinein chronic inflammatory disease. Joint Bone Spine 2008; 75: 517-9.
    • (2008) Joint Bone Spine , vol.75 , pp. 517-519
    • Wendling, D.1
  • 101
    • 37349131221 scopus 로고    scopus 로고
    • Pathophysiology of psoriasis: Recent advances on IL-23 and Th17 cytokines
    • Fitch E, Harper E, Skorcheva I, et al. Pathophysiology of psoriasis: recent advances on IL-23 and Th17 cytokines. Curr Rheumatol Rep 2007; 9: 461-467.
    • (2007) Curr Rheumatol Rep , vol.9 , pp. 461-467
    • Fitch, E.1    Harper, E.2    Skorcheva, I.3
  • 102
    • 0036604306 scopus 로고    scopus 로고
    • A receptor for the hetero- dimeric cytokine IL-23 is composed of IL-12Rbeta1 and a novel cytokine receptor subunit, IL-23R
    • Parham C et al. A receptor for the hetero- dimeric cytokine IL-23 is composed of IL-12Rbeta1 and a novel cytokine receptor subunit, IL-23R. J Immunol 2002; 168: 5699-5708.
    • (2002) J Immunol , vol.168 , pp. 5699-5708
    • Parham, C.1
  • 103
    • 34247523141 scopus 로고    scopus 로고
    • Discovery and biology of IL-23 and IL-27: Related but functionally distinct regulators of inflammation
    • Kastelein RA, Hunter CA, Cua DJ. Discovery and biology of IL-23 and IL-27: related but functionally distinct regulators of inflammation. Annu Rev Immunol 2007; 25: 221-242.
    • (2007) Annu Rev Immunol , vol.25 , pp. 221-242
    • Kastelein, R.A.1    Hunter, C.A.2    Cua, D.J.3
  • 104
    • 34547774225 scopus 로고    scopus 로고
    • Sequence variants in the genes for the interleukin-23 receptor (IL23R) and its ligand (IL12B) confer protection against psoriasis
    • Capon F, Di Meglio P, Szaub J et al. Sequence variants in the genes for the interleukin-23 receptor (IL23R) and its ligand (IL12B) confer protection against psoriasis. Hum Genet 2007; 122: 201-206.
    • (2007) Hum Genet , vol.122 , pp. 201-206
    • Capon, F.1    di Meglio, P.2    Szaub, J.3
  • 105
    • 33846608131 scopus 로고    scopus 로고
    • A large-scale genetic association study confirms IL12B and leads to the identification of IL23R as psoriasis-risk genes
    • Cargill M, Schrodi SJ, Chang M et al. A large-scale genetic association study confirms IL12B and leads to the identification of IL23R as psoriasis-risk genes. Am J Hum Genet 2007; 80: 273-290.
    • (2007) Am J Hum Genet , vol.80 , pp. 273-290
    • Cargill, M.1    Schrodi, S.J.2    Chang, M.3
  • 108
    • 27544490377 scopus 로고    scopus 로고
    • Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from theThelper type1and2lineages
    • Harrington LE, Hatton RD, Mangan PR et al. Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from theThelper type1and2lineages.Nat Immunol 2005;6:1123-1132.
    • (2005) Nat Immunol , vol.6 , pp. 1123-1132
    • Harrington, L.E.1    Hatton, R.D.2    Mangan, P.R.3
  • 109
    • 13244283212 scopus 로고    scopus 로고
    • IL-23 drives a pathogenic T cell population that induces autoimmune inflammation
    • Langrish CL, Chen Y, Blumenschein WM et al. IL-23 drives a pathogenic T cell population that induces autoimmune inflammation. J Exp Med 2005; 201: 233-240.
    • (2005) J Exp Med , vol.201 , pp. 233-240
    • Langrish, C.L.1    Chen, Y.2    Blumenschein, W.M.3
  • 110
    • 55149090692 scopus 로고    scopus 로고
    • Th17 cytokines and mucosal immunity
    • Dubin PJ, Kolls JK. Th17 cytokines and mucosal immunity. Immunol Rev 2008; 226: 160-171.
    • (2008) Immunol Rev , vol.226 , pp. 160-171
    • Dubin, P.J.1    Kolls, J.K.2
  • 111
    • 78650706586 scopus 로고    scopus 로고
    • Cutting Edge: A Critical Functional Role for IL-23 in Psoriasis
    • Tonel G, Conrad C, Laggner U et al. Cutting Edge: A Critical Functional Role for IL-23 in Psoriasis. J Immunol 2010; 185: 5688-569.
    • (2010) J Immunol , vol.185 , pp. 5688-5689
    • Tonel, G.1    Conrad, C.2    Laggner, U.3
  • 112
    • 31144441631 scopus 로고    scopus 로고
    • In vitro and in situ expression of IL-23 by keratinocytes in healthy skin and psoriasis lesions: Enhanced expression in psoriatic skin
    • Piskin G, Sylva-Steenland RM, Bos JD, Teunissen MB. In vitro and in situ expression of IL-23 by keratinocytes in healthy skin and psoriasis lesions: enhanced expression in psoriatic skin. J Immunol 2006; 176: 1908-1915.
    • (2006) J Immunol , vol.176 , pp. 1908-1915
    • Piskin, G.1    Sylva-Steenland, R.M.2    Bos, J.D.3    Teunissen, M.B.4
  • 113
    • 33751546237 scopus 로고    scopus 로고
    • IL-23 stimulates epidermal hyperplasia via TNF and IL-20R2-dependent mechanisms with implications for psoriasis pathogenesis
    • Chan JR, Blumenschein W, Murphy E et al. IL-23 stimulates epidermal hyperplasia via TNF and IL-20R2-dependent mechanisms with implications for psoriasis pathogenesis. J Exp Med 2006; 203: 2577-2587.
    • (2006) J Exp Med , vol.203 , pp. 2577-2587
    • Chan, J.R.1    Blumenschein, W.2    Murphy, E.3
  • 114
    • 0347285359 scopus 로고    scopus 로고
    • Increased expression of interleukin 23 p19 and p40 in lesional skinof patients with psoriasis vulgaris
    • Lee E, Trepicchio WL, Oestreicher JL, etal. Increased expression of interleukin 23 p19 and p40 in lesional skinof patients with psoriasis vulgaris. J Exp Med 2004; 199: 125-130.
    • (2004) J Exp Med , vol.199 , pp. 125-130
    • Lee, E.1    Trepicchio, W.L.2    Oestreicher, J.L.3
  • 115
    • 77950182023 scopus 로고    scopus 로고
    • Genetic variations associated with psoriasis and psoriatic arthritis found by genome-wide association
    • Duffin KC, Woodcock J, Krueger GG. Genetic variations associated with psoriasis and psoriatic arthritis found by genome-wide association. Dermatol Ther 2010; 23: 101-111.
    • (2010) Dermatol Ther , vol.23 , pp. 101-111
    • Duffin, K.C.1    Woodcock, J.2    Krueger, G.G.3
  • 116
    • 77955058853 scopus 로고    scopus 로고
    • The role of IL-23 in the immunopathogen-esis of psoriasis
    • Di Meglio P, Nestle FO. The role of IL-23 in the immunopathogen-esis of psoriasis. F1000 Biol Rep 2010; 2: 40.
    • (2010) F1000 Biol Rep , vol.2 , pp. 40
    • di Meglio, P.1    Nestle, F.O.2
  • 117
    • 33846906224 scopus 로고    scopus 로고
    • Interleukin-22, a T(H)17 cytokine, mediates IL-23-induced dermal inflammation and acanthosis
    • Zheng Y et al. Interleukin-22, a T(H)17 cytokine, mediates IL-23-induced dermal inflammation and acanthosis. Nature 2007; 445: 648-651.
    • (2007) Nature , vol.445 , pp. 648-651
    • Zheng, Y.1
  • 118
    • 33749151636 scopus 로고    scopus 로고
    • An anti-IL-12p40 antibody down-regulates type 1 cytokines, chemokines, and IL-12/IL-23 in psoriasis
    • Toichi E et al. An anti-IL-12p40 antibody down-regulates type 1 cytokines, chemokines, and IL-12/IL-23 in psoriasis. J Immunol 2006; 177: 4917-4926.
    • (2006) J Immunol , vol.177 , pp. 4917-4926
    • Toichi, E.1
  • 119
    • 73249116548 scopus 로고    scopus 로고
    • The Th17 cytokine IL-22 induces IL-20 production in keratinocytes: Anovel immuno- logical cascade with potential relevance in psoriasis
    • Wolk K, Witte E, Warszawska K et al. The Th17 cytokine IL-22 induces IL-20 production in keratinocytes: anovel immuno- logical cascade with potential relevance in psoriasis. Eur J Immunol 2009; 39: 3570-3581.
    • (2009) Eur J Immunol , vol.39 , pp. 3570-3581
    • Wolk, K.1    Witte, E.2    Warszawska, K.3
  • 120
    • 0036604122 scopus 로고    scopus 로고
    • Cutting edge: Immune cells as sources and targets of the IL-10 family members?
    • Wolk K, Kunz S, Asadullah K, Sabat R. Cutting edge: immune cells as sources and targets of the IL-10 family members? J Immunol 2002; 168: 5397-5402.
    • (2002) J Immunol , vol.168 , pp. 5397-5402
    • Wolk, K.1    Kunz, S.2    Asadullah, K.3    Sabat, R.4
  • 121
    • 46949101054 scopus 로고    scopus 로고
    • Maturing dendritic cells are an important source of IL-29 and IL-20 that may cooperatively increase the innate immunity of keratinocytes
    • Wolk K, Witte K, Witte E et al. Maturing dendritic cells are an important source of IL-29 and IL-20 that may cooperatively increase the innate immunity of keratinocytes. J Leukoc Biol 2008; 83: 1181-1193.
    • (2008) J Leukoc Biol , vol.83 , pp. 1181-1193
    • Wolk, K.1    Witte, K.2    Witte, E.3
  • 122
    • 33750628576 scopus 로고    scopus 로고
    • Interleukin (IL)-19, IL-20 and IL-24 are produced by and act on keratinocytes and are di- stinct from classical ILs
    • Kunz S, Wolk K, Witte E et al. Interleukin (IL)-19, IL-20 and IL-24 are produced by and act on keratinocytes and are di- stinct from classical ILs. Exp Dermatol 2006; 15: 991-1004.
    • (2006) Exp Dermatol , vol.15 , pp. 991-1004
    • Kunz, S.1    Wolk, K.2    Witte, E.3
  • 123
    • 34248370876 scopus 로고    scopus 로고
    • IL-19 and IL-20: Two novel cytokines with importance in inflam- matory diseases
    • Sabat R, Wallace E, Endesfelder S, Wolk K. IL-19 and IL-20: two novel cytokines with importance in inflam- matory diseases. Expert Opin Ther Targets 2007; 11: 601-612.
    • (2007) Expert Opin Ther Targets , vol.11 , pp. 601-612
    • Sabat, R.1    Wallace, E.2    Endesfelder, S.3    Wolk, K.4
  • 124
    • 67349195975 scopus 로고    scopus 로고
    • IL-22 and IL-20 are key mediators of the epidermal alterations in psoriasis while IL-17 and IFN-gamma are not
    • Wolk K, Haugen HS, Xu W et al. IL-22 and IL-20 are key mediators of the epidermal alterations in psoriasis while IL-17 and IFN-gamma are not. J Mol Med 2009; 87: 523-536.
    • (2009) J Mol Med , vol.87 , pp. 523-536
    • Wolk, K.1    Haugen, H.S.2    Xu, W.3
  • 125
    • 0038665233 scopus 로고    scopus 로고
    • IL-15 promotes the survival of naïve and memory phenotype CD8+ T cells
    • Berard M, Brandt K, Bulfone-Paus S, Tough DF. IL-15 promotes the survival of naïve and memory phenotype CD8+ T cells. J Immunol 2003; 170: 5018-5026.
    • (2003) J Immunol , vol.170 , pp. 5018-5026
    • Berard, M.1    Brandt, K.2    Bulfone-Paus, S.3    Tough, D.F.4
  • 126
    • 0346363236 scopus 로고    scopus 로고
    • IL-15 in the life and death of lymphocytes: Immunotherapeutic implications
    • Waldmann TA. IL-15 in the life and death of lymphocytes: immunotherapeutic implications. Trends Mol Med 2003; 9: 517-521.
    • (2003) Trends Mol Med , vol.9 , pp. 517-521
    • Waldmann, T.A.1
  • 127
    • 35348876050 scopus 로고    scopus 로고
    • IL-15 and psoriasis: Another genetic link to Th17?
    • Elder JT. IL-15 and psoriasis: another genetic link to Th17? J Invest Dermatol 2007; 127: 2495-2497.
    • (2007) J Invest Dermatol , vol.127 , pp. 2495-2497
    • Elder, J.T.1
  • 128
    • 0034663951 scopus 로고    scopus 로고
    • Inhibition of keratinocyte apoptosis by IL- 15: A new parameter in the pathogenesis of psoriasis
    • Rückert R, Asadullah K, Seifert M et al. Inhibition of keratinocyte apoptosis by IL- 15: a new parameter in the pathogenesis of psoriasis. J Immunol 2000; 165: 2240-2250.
    • (2000) J Immunol , vol.165 , pp. 2240-2250
    • Rückert, R.1    Asadullah, K.2    Seifert, M.3
  • 129
    • 0034086893 scopus 로고    scopus 로고
    • Macrophage-derived cytokine and nuclear factorkBp65 expressionn synovial membrane and skinof patients with psoriatic arthritis
    • Danning CL, Illei GG, Hitchon C et al. Macrophage-derived cytokine and nuclear factorkBp65 expressionn synovial membrane and skinof patients with psoriatic arthritis. Arthritis Rheumat 2000; 43: 1244-1256.
    • (2000) Arthritis Rheumat , vol.43 , pp. 1244-1256
    • Danning, C.L.1    Illei, G.G.2    Hitchon, C.3
  • 130
    • 5644304287 scopus 로고    scopus 로고
    • Reduction of synovial sublin-ing layer inflammation and proinflamma- tory cytokine expression in psoriatic arthritis treated with methotrexate
    • Kane D, Gogarty M, O'Leary J et al. Reduction of synovial sublin-ing layer inflammation and proinflamma- tory cytokine expression in psoriatic arthritis treated with methotrexate. Arthritis Rheumat 2004; 50: 3286-3295.
    • (2004) Arthritis Rheumat , vol.50 , pp. 3286-3295
    • Kane, D.1    Gogarty, M.2    O'Leary, J.3
  • 131
    • 0037459033 scopus 로고    scopus 로고
    • Interleukin 15 induces the signals of epiderma proliferation through ERK and PI 3-kinase In a human epiderma keratinocyte cell line, HaCaT
    • Yano S, Komine M, Fujimoto M et al. Interleukin 15 induces the signals of epiderma proliferation through ERK and PI 3-kinase In a human epiderma keratinocyte cell line, HaCaT. Biochem Biophys Res Commun 2003; 301: 841-847.
    • (2003) Biochem Biophys Res Commun , vol.301 , pp. 841-847
    • Yano, S.1    Komine, M.2    Fujimoto, M.3
  • 132
    • 0035169507 scopus 로고    scopus 로고
    • Interleukin 15: Biology and relevance to human disease
    • Fehniger TA, Caligiuri MA. Interleukin 15: biology and relevance to human disease. Blood 2001; 97: 14-32.
    • (2001) Blood , vol.97 , pp. 14-32
    • Fehniger, T.A.1    Caligiuri, M.A.2
  • 133
    • 3342897676 scopus 로고    scopus 로고
    • Interleukin-15:Anew cytokine target for the treatment of inflammatory diseases
    • McInnes IB, Gracie JA. Interleukin-15:anew cytokine target for the treatment of inflammatory diseases. Curr Opin Pharmacol 2004; 4: 392-397.
    • (2004) Curr Opin Pharmacol , vol.4 , pp. 392-397
    • McInnes, I.B.1    Gracie, J.A.2
  • 134
    • 0346096722 scopus 로고    scopus 로고
    • Resolution of psoriasis upon blockade of IL- 15 biological activity in a xenograft mouse model
    • Villadsen LS, Schuurman J, Beurskens F et al. Resolution of psoriasis upon blockade of IL- 15 biological activity in a xenograft mouse model. J Clin Invest 2003; 112:1571-1580.
    • (2003) J Clin Invest , vol.112 , pp. 1571-1580
    • Villadsen, L.S.1    Schuurman, J.2    Beurskens, F.3
  • 135
    • 33846195438 scopus 로고    scopus 로고
    • Follow-up analysis of PSORS9 in 151 Chinese families confirmed the linkage to 4q31-32 and refined the evidence to the families of early-onset psoriasis
    • Yan KL, Huang W, Zhang XJ et al. Follow-up analysis of PSORS9 in 151 Chinese families confirmed the linkage to 4q31-32 and refined the evidence to the families of early-onset psoriasis. J Invest Dermatol 2007; 127: 312-318.
    • (2007) J Invest Dermatol , vol.127 , pp. 312-318
    • Yan, K.L.1    Huang, W.2    Zhang, X.J.3
  • 136
    • 35348829138 scopus 로고    scopus 로고
    • Polymorphisms in interleukin-15 gene on chromosome 4q31.2 are associated with psoriasis vulgaris in Chinese population
    • Zhang XJ, Yan KL, Wang ZM et al. Polymorphisms in interleukin-15 gene on chromosome 4q31.2 are associated with psoriasis vulgaris in Chinese population. J Invest Dermatol 2007; 127: 2544-2551.
    • (2007) J Invest Dermatol , vol.127 , pp. 2544-2551
    • Zhang, X.J.1    Yan, K.L.2    Wang, Z.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.