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Volumn 18, Issue 9, 2011, Pages 850-857

CDB-4124 does not cause apoptosis in cultured fibroid cells

Author keywords

apoptosis; cleaved caspase 3; selective progesterone receptor modulators; TUNEL; uterine fibroids

Indexed keywords

CASPASE 3; DACTINOMYCIN; STAUROSPORINE; TELAPRISTONE ACETATE;

EID: 80051988006     PISSN: 19337191     EISSN: 19337205     Source Type: Journal    
DOI: 10.1177/1933719111399929     Document Type: Article
Times cited : (14)

References (32)
  • 1
    • 5044236959 scopus 로고    scopus 로고
    • Comparative ultrastructure of collagen fibrils in uterine leiomyomas and normal myometrium
    • DOI 10.1016/j.fertnstert.2004.04.030, PII S0015028204011355
    • Leppert PC, Baginski T, Prupas C, Catherino WH, Pletcher S, Segars JH. Comparative ultrastructure of collagen fibrils in uterine leiomyomas and normal myometrium. Fertil Steril. 2004 ; 82 (3). 1182-1187 (Pubitemid 39335936)
    • (2004) Fertility and Sterility , vol.82 , Issue.SUPPL. 3 , pp. 1182-1187
    • Leppert, P.C.1    Baginski, T.2    Prupas, C.3    Catherino, W.H.4    Pletcher, S.5    Segars, J.H.6
  • 3
    • 0024529534 scopus 로고
    • A randomized, placebo-controlled, double-blind study evaluating the efficacy of leuprolide acetate depot in the treatment of uterine leiomyomata
    • Friedman AJ, Harrison-Atlas D, Barbieri RL, Benacerraf B, Gleason R, Schiff I. A randomized, placebo-controlled, double-blind study evaluating the efficacy of leuprolide acetate depot in the treatment of uterine leiomyomata. Fertil Steril. 1989 ; 51 (2). 251-256 (Pubitemid 19050523)
    • (1989) Fertility and Sterility , vol.51 , Issue.2 , pp. 251-256
    • Friedman, A.J.1    Harrison-Atlas, D.2    Barbieri, R.L.3    Benacerraf, B.4    Gleason, R.5    Schiff, I.6
  • 4
    • 0033664553 scopus 로고    scopus 로고
    • Advances in uterine leiomyoma research: The progesterone hypothesis
    • Rein MS. Advances in uterine leiomyoma research: the progesterone hypothesis. Environ Health Perspect. 2000 ; 108 (suppl 5). 791-793
    • (2000) Environ Health Perspect , vol.108 , Issue.SUPPL. 5 , pp. 791-793
    • Rein, M.S.1
  • 5
    • 0027278471 scopus 로고
    • An evaluation of the effect of gonadotropin-releasing hormone analogs and medroxyprogesterone acetate on uterine leiomyomata volume by magnetic resonance imaging: A prospective, randomized, double blind, placebo- controlled, crossover trial
    • DOI 10.1210/jc.76.5.1217
    • Carr BR, Marshburn PB, Weatherall PT, et al. An evaluation of the effect of gonadotropin-releasing hormone analogs and medroxyprogesterone acetate on uterine leiomyomata volume by magnetic resonance imaging: a prospective, randomized, double blind, placebo-controlled, crossover trial. J Clin Endocrinol Metab. 1993 ; 76 (5). 1217-1223 (Pubitemid 23155439)
    • (1993) Journal of Clinical Endocrinology and Metabolism , vol.76 , Issue.5 , pp. 1217-1223
    • Carr, B.R.1    Marshburn, P.B.2    Weatherall, P.T.3    Bradshaw, K.D.4    Breslau, N.A.5    Byrd, W.6    Roark, M.7    Steinkampf, M.P.8
  • 6
    • 67249100911 scopus 로고    scopus 로고
    • Gynaecological uses of a new class of steroids: The selective progesterone receptor modulators
    • Pintiaux A, Chabbert-Buffet N, Foidart JM. Gynaecological uses of a new class of steroids: the selective progesterone receptor modulators. Gynecol Endocrinol. 2009 ; 25 (2). 67-73
    • (2009) Gynecol Endocrinol , vol.25 , Issue.2 , pp. 67-73
    • Pintiaux, A.1    Chabbert-Buffet, N.2    Foidart, J.M.3
  • 7
    • 67651100786 scopus 로고    scopus 로고
    • Mifepristone for treatment of uterine leiomyoma. A prospective randomized placebo controlled trial
    • Engman M, Granberg S, Williams AR, Meng CX, Lalitkumar PG, Gemzell-Danielsson K. Mifepristone for treatment of uterine leiomyoma. A prospective randomized placebo controlled trial. Hum Reprod. 2009 ; 24 (8). 1870-1879
    • (2009) Hum Reprod , vol.24 , Issue.8 , pp. 1870-1879
    • Engman, M.1    Granberg, S.2    Williams, A.R.3    Meng, C.X.4    Lalitkumar, P.G.5    Gemzell-Danielsson, K.6
  • 8
    • 34249712002 scopus 로고    scopus 로고
    • A randomized, controlled trial of asoprisnil, a novel selective progesterone receptor modulator, in women with uterine leiomyomata
    • DOI 10.1016/j.fertnstert.2006.11.094, PII S001502820604533X
    • Chwalisz K, Larsen L, Mattia-Goldberg C, Edmonds A, Elger W, Winkel CA. A randomized, controlled trial of asoprisnil, a novel selective progesterone receptor modulator, in women with uterine leiomyomata. Fertil Steril. 2007 ; 87 (6). 1399-1412 (Pubitemid 46829155)
    • (2007) Fertility and Sterility , vol.87 , Issue.6 , pp. 1399-1412
    • Chwalisz, K.1    Larsen, L.2    Mattia-Goldberg, C.3    Edmonds, A.4    Elger, W.5    Winkel, C.A.6
  • 9
    • 33646067165 scopus 로고    scopus 로고
    • A novel selective progesterone receptor modulator asoprisnil (J867) inhibits proliferation and induces apoptosis in cultured human uterine leiomyoma cells in the absence of comparable effects on myometrial cells
    • Chen W, Ohara N, Wang J, et al. A novel selective progesterone receptor modulator asoprisnil (J867) inhibits proliferation and induces apoptosis in cultured human uterine leiomyoma cells in the absence of comparable effects on myometrial cells. J Clin Endocrinol Metab. 2006 ; 91 (4). 1296-304
    • (2006) J Clin Endocrinol Metab , vol.91 , Issue.4 , pp. 1296-304
    • Chen, W.1    Ohara, N.2    Wang, J.3
  • 10
    • 38749121786 scopus 로고    scopus 로고
    • Comparative effects of SPRM asoprisnil (J867) on proliferation, apoptosis, and the expression of growth factors in cultured uterine leiomyoma cells and normal myometrial cells
    • Ohara N, Morikawa A, Chen W, et al. Comparative effects of SPRM asoprisnil (J867) on proliferation, apoptosis, and the expression of growth factors in cultured uterine leiomyoma cells and normal myometrial cells. Reprod Sci. 2007 ; 14 (8 suppl). 20-27
    • (2007) Reprod Sci , vol.14 , Issue.8 SUPPL. , pp. 20-27
    • Ohara, N.1    Morikawa, A.2    Chen, W.3
  • 12
    • 14044251610 scopus 로고    scopus 로고
    • Progesterone receptor modulator CDB-2914 down-regulates proliferative cell nuclear antigen and Bcl-2 protein expression and up-regulates caspase-3 and poly(adenosine 5′-diphosphate-ribose) polymerase expression in cultured human uterine leiomyoma cells
    • DOI 10.1210/jc.2004-1569
    • Xu Q, Takekida S, Ohara N, et al. Progesterone receptor modulator CDB-2914 down-regulates proliferative cell nuclear antigen and Bcl-2 protein expression and up-regulates caspase-3 and poly(adenosine 5'-diphosphate-ribose) polymerase expression in cultured human uterine leiomyoma cells. J Clin Endocrinol Metab. 2005 ; 90 (2). 953-961 (Pubitemid 40279221)
    • (2005) Journal of Clinical Endocrinology and Metabolism , vol.90 , Issue.2 , pp. 953-961
    • Xu, Q.1    Takekida, S.2    Ohara, N.3    Chen, W.4    Sitruk-Ware, R.5    Johansson, E.D.B.6    Maruo, T.7
  • 13
    • 0037169814 scopus 로고    scopus 로고
    • CDB-4124 and its putative monodemethylated metabolite, CDB-4453, are potent antiprogestins with reduced antiglucocorticoid activity: In vitro comparison to mifepristone and CDB-2914
    • PII S0303720701007432
    • Attardi BJ, Burgenson J, Hild SA, Reel JR, Blye RP. CDB-4124 and its putative monodemethylated metabolite, CDB-4453, are potent antiprogestins with reduced antiglucocorticoid activity: in vitro comparison to mifepristone and CDB-2914. Mol Cell Endocrinol. 2002 ; 188 (1-2). 111-123 (Pubitemid 34242671)
    • (2002) Molecular and Cellular Endocrinology , vol.188 , Issue.1-2 , pp. 111-123
    • Attardi, B.J.1    Burgenson, J.2    Hild, S.A.3    Reel, J.R.4    Blye, R.P.5
  • 14
    • 68949190174 scopus 로고    scopus 로고
    • Effects of a new progesterone receptor modulator, CDB-4124, on fibroid size and uterine bleeding. (US obstetrics and Gynecology)
    • Wiehle RB, Goldberg J, Brodniewicz T, Dziedzic KJ, Jabiry-Zieniewicz Z. Effects of a new progesterone receptor modulator, CDB-4124, on fibroid size and uterine bleeding. (US obstetrics and Gynecology). Touch Briefings. 2008 ; 3 (1). 17-20
    • (2008) Touch Briefings , vol.3 , Issue.1 , pp. 17-20
    • Wiehle, R.B.1    Goldberg, J.2    Brodniewicz, T.3    Dziedzic, K.J.4    Jabiry-Zieniewicz, Z.5
  • 15
    • 61349195008 scopus 로고    scopus 로고
    • Endometrial changes from short-term therapy with CDB-4124, a selective progesterone receptor modulator
    • Ioffe OB, Zaino RJ, Mutter GL. Endometrial changes from short-term therapy with CDB-4124, a selective progesterone receptor modulator. Mod Pathol. 2009 ; 22 (3). 450-459
    • (2009) Mod Pathol , vol.22 , Issue.3 , pp. 450-459
    • Ioffe, O.B.1    Zaino, R.J.2    Mutter, G.L.3
  • 16
    • 49649086951 scopus 로고    scopus 로고
    • Retinoic acid treatment of human leiomyoma cells transformed the cell phenotype to one strongly resembling myometrial cells
    • Malik M, Webb J, Catherino WH. Retinoic acid treatment of human leiomyoma cells transformed the cell phenotype to one strongly resembling myometrial cells. Clin Endocrinol (Oxf). 2008 ; 69 (3). 462-470
    • (2008) Clin Endocrinol (Oxf) , vol.69 , Issue.3 , pp. 462-470
    • Malik, M.1    Webb, J.2    Catherino, W.H.3
  • 17
    • 65049088214 scopus 로고    scopus 로고
    • Curcumin, a nutritional supplement with antineoplastic activity, enhances leiomyoma cell apoptosis and decreases fibronectin expression
    • Malik M, Mendoza M, Payson M, Catherino W. Curcumin, a nutritional supplement with antineoplastic activity, enhances leiomyoma cell apoptosis and decreases fibronectin expression. Fertil Steril. 2009 ; 91 (5). 2177-2184
    • (2009) Fertil Steril , vol.91 , Issue.5 , pp. 2177-2184
    • Malik, M.1    Mendoza, M.2    Payson, M.3    Catherino, W.4
  • 18
    • 0028242089 scopus 로고
    • Protein kinase C inhibitors induce apoptosis in human malignant glioma cell lines
    • DOI 10.1016/0014-5793(94)00415-3
    • Couldwell WT, Hinton DR, He S, et al. Protein kinase C inhibitors induce apoptosis in human malignant glioma cell lines. FEBS Lett. 1994 ; 345 (1). 43-46 (Pubitemid 24154662)
    • (1994) FEBS Letters , vol.345 , Issue.1 , pp. 43-46
    • Couldwell, W.T.1
  • 19
    • 65949093262 scopus 로고    scopus 로고
    • Progesterone-regulated caspase 3 action in the mouse may play a role in uterine quiescence during pregnancy through fragmentation of uterine myocyte contractile proteins
    • Jeyasuria P, Wetzel J, Bradley M, Subedi K, Condon J. Progesterone-regulated caspase 3 action in the mouse may play a role in uterine quiescence during pregnancy through fragmentation of uterine myocyte contractile proteins. Biol Reprod. 2009 ; 80 (5). 928-934
    • (2009) Biol Reprod , vol.80 , Issue.5 , pp. 928-934
    • Jeyasuria, P.1    Wetzel, J.2    Bradley, M.3    Subedi, K.4    Condon, J.5
  • 20
    • 77950640187 scopus 로고    scopus 로고
    • Multimodal regulation of E2F1 gene expression by progestins
    • Wade H, Kobayashi S, Eaton M, et al. Multimodal regulation of E2F1 gene expression by progestins. Mol Cell Biol. 2010 ; 30 (8). 1866-1877
    • (2010) Mol Cell Biol , vol.30 , Issue.8 , pp. 1866-1877
    • Wade, H.1    Kobayashi, S.2    Eaton, M.3
  • 21
    • 34247523721 scopus 로고    scopus 로고
    • Novel method to characterize primary cultures of leiomyoma and myometrium with the use of confirmatory biomarker gene arrays
    • Malik M, Catherino WH. Novel method to characterize primary cultures of leiomyoma and myometrium with the use of confirmatory biomarker gene arrays. Fertil Steril. 2007 ; 87 (5). 116-172
    • (2007) Fertil Steril , vol.87 , Issue.5 , pp. 116-172
    • Malik, M.1    Catherino, W.H.2
  • 22
    • 77957272596 scopus 로고    scopus 로고
    • Novel, orally active selective progesterone receptor modulator CP8947 inhibits leiomyoma cell proliferation without adversely affecting endometrium or myometrium
    • Catherino WH, Malik M, Driggers P, Chappel S, Segars J, Davis J. Novel, orally active selective progesterone receptor modulator CP8947 inhibits leiomyoma cell proliferation without adversely affecting endometrium or myometrium. J Steroid Biochem Mol Biol. 2010 ; 122 (4). 279-286
    • (2010) J Steroid Biochem Mol Biol , vol.122 , Issue.4 , pp. 279-286
    • Catherino, W.H.1    Malik, M.2    Driggers, P.3    Chappel, S.4    Segars, J.5    Davis, J.6
  • 23
    • 77952110601 scopus 로고    scopus 로고
    • The selective progesterone receptor modulator CDB4124 inhibits proliferation and induces apoptosis in uterine leiomyoma cells
    • Luo X, Yin P, Coon VJ, Cheng YH, Wiehle RD, Bulun SE. The selective progesterone receptor modulator CDB4124 inhibits proliferation and induces apoptosis in uterine leiomyoma cells. Fertil Steril. 2010 ; 93 (8). 2668-2673
    • (2010) Fertil Steril , vol.93 , Issue.8 , pp. 2668-2673
    • Luo, X.1    Yin, P.2    Coon, V.J.3    Cheng, Y.H.4    Wiehle, R.D.5    Bulun, S.E.6
  • 24
    • 78349261571 scopus 로고    scopus 로고
    • Effects of GnRH agonist treatment on steroidogenesis and folliculogenesis in the ovary of cyclic mice
    • Singh P, Krishna A. Effects of GnRH agonist treatment on steroidogenesis and folliculogenesis in the ovary of cyclic mice. J Ovarian Res. 2010 ; 3: 26
    • (2010) J Ovarian Res , vol.3 , pp. 26
    • Singh, P.1    Krishna, A.2
  • 28
    • 43449112674 scopus 로고    scopus 로고
    • Molecular and cytogenetic characterization of plexiform leiomyomata provide further evidence for genetic heterogeneity underlying uterine fibroids
    • DOI 10.2353/ajpath.2008.071102
    • Hodge J, Quade B, Rubin M. Molecular and cytogenetic characterization of plexiform leiomyomata provide further evidence for genetic heterogeneity underlying uterine fibroids. Am J Pathol. 2008 ; 172 (5). 1403-1410 (Pubitemid 351671552)
    • (2008) American Journal of Pathology , vol.172 , Issue.5 , pp. 1403-1410
    • Hodge, J.C.1    Quade, B.J.2    Rubin, M.A.3    Stewart, E.A.4    Cin, P.D.5    Morton, C.C.6
  • 30
    • 44249127287 scopus 로고    scopus 로고
    • Selective progesterone receptor modulator asoprisnil down-regulates collagen synthesis in cultured human uterine leiomyoma cells through up-regulating extracellular matrix metalloproteinase inducer
    • Morikawa A, Ohara N, Xu Q, et al. Selective progesterone receptor modulator asoprisnil down-regulates collagen synthesis in cultured human uterine leiomyoma cells through up-regulating extracellular matrix metalloproteinase inducer. Hum Reprod. 2008 ; 23 (4). 944-951
    • (2008) Hum Reprod , vol.23 , Issue.4 , pp. 944-951
    • Morikawa, A.1    Ohara, N.2    Xu, Q.3
  • 31
    • 40949109661 scopus 로고    scopus 로고
    • Progesterone receptor modulator CDB-2914 induces extracellular matrix metalloproteinase inducer in cultured human uterine leiomyoma cells
    • DOI 10.1093/molehr/gan004
    • Xu Q, Ohara N, Liu J, et al. Progesterone receptor modulator CDB-2914 induces extracellular matrix metalloproteinase inducer in cultured human uterine leiomyoma cells. Mol Hum Reprod. 2008 ; 14 (3). 181-191 (Pubitemid 351404891)
    • (2008) Molecular Human Reproduction , vol.14 , Issue.3 , pp. 181-191
    • Xu, Q.1    Ohara, N.2    Liu, J.3    Amano, M.4    Sitruk-Ware, R.5    Yoshida, S.6    Maruo, T.7
  • 32
    • 33749545197 scopus 로고    scopus 로고
    • Progesterone receptor modulator CDB-2914 down-regulates vascular endothelial growth factor, adrenomedullin and their receptors and modulates progesterone receptor content in cultured human uterine leiomyoma cells
    • DOI 10.1093/humrep/del159
    • Xu Q, Ohara N, Chen W, et al. Progesterone receptor modulator CDB-2914 down-regulates vascular endothelial growth factor, adrenomedullin and their receptors and modulates progesterone receptor content in cultured human uterine leiomyoma cells. Hum Reprod. 2006 ; 21 (9). 2408-2416 (Pubitemid 44530620)
    • (2006) Human Reproduction , vol.21 , Issue.9 , pp. 2408-2416
    • Xu, Q.1    Ohara, N.2    Chen, W.3    Liu, J.4    Sasaki, H.5    Morikawa, A.6    Sitruk-Ware, R.7    Johansson, E.D.B.8    Maruo, T.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.